Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86240835 | . | C | A | CCDS6237.1:NM_001128829.2:c.740cGc>cTc_NP_001122301.1:p.247R>L | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | ARG | A:247 | A:246 | 5.0 | 0.022 | -89.7 | 141.3 | 5.0 | 0.022 | 0.0 |
ZN 949 HOH |
8.437 8.098 2.730 |
N CB O |
ZN N22 O |
|||
| ARG | B:247 | B:246 | 4.0 | 0.018 | -86.3 | 145.4 | NA | NA | NA | ||||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ARG | A:247 | A:246 | 5.0 | 0.022 | -86.0 | 142.1 | 5.0 | 0.022 | 0.0 |
ZN BZW ACT HOH |
8.334 8.083 5.056 2.816 |
N CB O O |
ZN N27 OXT O |
|||
| ARG | B:247 | B:246 | 5.0 | 0.022 | -85.5 | 141.0 | NA | NA | NA | ||||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:247 | A:246 | 7.0 | 0.031 | -83.5 | 141.8 | 7.0 | 0.031 | 0.0 |
ZN N19 ACT HOH |
8.346 8.139 5.172 2.759 |
N CB O O |
ZN N28 OXT O |
|||
| ARG | B:247 | B:246 | 5.0 | 0.022 | -80.2 | 139.8 | NA | NA | NA | ||||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:247 | A:246 | 5.0 | 0.022 | -87.1 | 141.7 | 5.0 | 0.022 | 0.0 |
ZN CJK ACT HOH |
8.399 8.009 5.019 2.668 |
N CB O O |
ZN N23 OXT O |
|||
| ARG | B:247 | B:246 | 4.0 | 0.018 | -84.6 | 140.7 | NA | NA | NA | ||||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:247 | A:246 | 8.0 | 0.036 | -85.6 | 141.6 | 8.0 | 0.036 | 0.0 |
ZN D3B HOH |
8.340 8.014 3.074 |
N CB O |
ZN N5 O |
|||
| ARG | B:247 | B:246 | 3.0 | 0.013 | -86.3 | 139.1 | NA | NA | NA | ||||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:247 | A:246 | 7.0 | 0.031 | -87.6 | 141.1 | 7.0 | 0.031 | 0.0 |
ZN EON HOH |
8.369 8.086 2.799 |
N CB O |
ZN N22 O |
|||
| ARG | B:247 | B:246 | 4.0 | 0.018 | -81.8 | 141.1 | NA | NA | NA | ||||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | ARG | A:247 | A:246 | 7.0 | 0.031 | -85.4 | 142.4 | 7.0 | 0.031 | 0.0 |
ZN FO9 HOH |
8.410 8.263 2.729 |
N CB NE |
ZN N6 O |
|||
| ARG | B:247 | B:246 | 5.0 | 0.022 | -78.0 | 137.5 | NA | NA | NA | ||||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | ARG | A:247 | A:247 | 6.0 | 0.027 | -92.9 | 143.2 | 6.0 | 0.027 | 0.0 |
ZN GXE HOH |
8.505 8.272 2.781 |
N CB O |
ZN SE O |
|||
| ARG | B:247 | B:247 | 4.0 | 0.018 | -88.4 | 140.4 | NA | NA | NA | ||||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:247 | A:246 | 6.0 | 0.027 | -83.9 | 141.2 | 6.0 | 0.027 | 0.0 |
ZN ACT GZE HOH |
8.449 5.037 8.097 2.809 |
N O CB O |
ZN OXT N6 O |
|||
| ARG | B:247 | B:246 | 5.0 | 0.022 | -82.2 | 140.1 | NA | NA | NA | ||||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:247 | A:246 | 5.0 | 0.022 | -83.9 | 141.4 | 5.0 | 0.022 | 0.0 |
ZN GZH ACT HOH |
8.410 8.152 5.064 2.830 |
N CB O O |
ZN N15 OXT O |
|||
| ARG | B:247 | B:246 | 4.0 | 0.018 | -86.4 | 141.0 | NA | NA | NA | ||||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | ARG | A:247 | A:246 | 7.0 | 0.031 | -96.8 | 145.5 | 7.0 | 0.031 | 0.0 |
ZN LVW HOH |
8.537 8.352 4.254 |
N CB C |
ZN SE O |
|||
| ARG | B:247 | B:246 | 6.0 | 0.027 | -91.9 | 133.0 | NA | NA | NA | ||||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 4.0 | 0.018 | -82.7 | 142.2 | 4.0 | 0.018 | 0.0 |
ZN O4Z HOH |
8.374 8.059 2.854 |
N CB O |
ZN N01 O |
|||
| ARG | B:247 | B:246 | 4.0 | 0.018 | -80.8 | 141.8 | NA | NA | NA | ||||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 6.0 | 0.027 | -86.3 | 145.2 | 6.0 | 0.027 | 0.0 |
ZN O55 HOH |
8.400 8.114 2.734 |
N CB O |
ZN N01 O |
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| ARG | B:247 | B:246 | 4.0 | 0.018 | -83.2 | 143.6 | NA | NA | NA | ||||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 5.0 | 0.022 | -80.4 | 142.7 | 5.0 | 0.022 | 0.0 |
ZN O5K HOH |
8.338 8.054 2.819 |
N CB O |
ZN N01 O |
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| ARG | B:247 | B:246 | 4.0 | 0.018 | -78.7 | 141.6 | NA | NA | NA | ||||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 4.0 | 0.018 | -84.4 | 141.1 | 4.0 | 0.018 | 0.0 |
ZN O5H HOH |
8.334 8.044 2.781 |
N CB NE |
ZN N01 O |
|||
| ARG | B:247 | B:246 | 3.0 | 0.013 | -84.6 | 141.6 | NA | NA | NA | ||||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 5.0 | 0.022 | -84.5 | 142.6 | 5.0 | 0.022 | 0.0 |
ZN O5N HOH |
8.388 8.035 2.687 |
N CB NE |
ZN N01 O |
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| ARG | B:247 | B:246 | 3.0 | 0.013 | -86.5 | 139.5 | NA | NA | NA | ||||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:247 | A:246 | 4.0 | 0.018 | -82.0 | 142.4 | 4.0 | 0.018 | 0.0 |
ZN O5T HOH |
8.360 8.134 2.797 |
N CB O |
ZN O03 O |
|||
| ARG | B:247 | B:246 | 3.0 | 0.013 | -81.0 | 141.5 | NA | NA | NA | ||||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ARG | A:247 | A:246 | 4.0 | 0.018 | -82.6 | 143.3 | 4.0 | 0.018 | 0.0 |
ZN 84Z EDO HOH |
8.385 8.181 4.728 2.812 |
N CD O O |
ZN CL1 O1 O |
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| ARG | B:247 | B:246 | 6.0 | 0.027 | -86.0 | 143.8 | NA | NA | NA | ||||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 4.0 | 0.018 | -96.7 | 142.1 | 4.0 | 0.018 | 0.0 |
ZN AZM HOH |
8.590 8.344 2.894 |
N CB NE |
ZN N1 O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 4.0 | 0.018 | -99.2 | 147.4 | 4.0 | 0.018 | 0.0 |
ZN MZM HOH |
8.621 8.371 2.818 |
N CB O |
ZN N1 O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 3.0 | 0.013 | -90.9 | 153.3 | 3.0 | 0.013 | 0.0 |
ZN AAS HOH |
8.556 8.333 2.916 |
N NH1 NE |
ZN O2 O |
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| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 5.0 | 0.022 | -82.8 | 142.7 | 5.0 | 0.022 | 0.0 |
ZN BCT HOH |
8.479 8.158 2.737 |
N CB O |
ZN O1 O |
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| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 4.0 | 0.018 | -106.4 | 144.4 | 4.0 | 0.018 | 0.0 |
ZN HOH |
8.552 2.647 |
N O |
ZN O |
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| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:246 | A:246 | 4.0 | 0.018 | -96.6 | 142.9 | 4.0 | 0.018 | 0.0 |
ZN IOD IOD IOD HOH |
8.494 8.972 5.040 5.966 2.502 |
N CB NE O NE |
ZN I I I O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | ARG | A:246 | A:246 | 5.0 | 0.022 | -90.6 | 142.3 | 5.0 | 0.022 | 0.0 |
ZN B30 B30 B30 HOH |
8.362 8.031 9.256 6.967 2.791 |
N CB N N O |
ZN N1 N1 O1 O |
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| ARG | B:246 | B:246 | 3.0 | 0.013 | -88.4 | 142.6 | NA | NA | NA | ||||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | ARG | A:246 | A:246 | 5.0 | 0.022 | -106.0 | 140.7 | 5.0 | 0.022 | 0.0 |
ZN HIS HOH |
8.558 9.677 2.778 |
N CD O |
ZN O O |
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| ARG | B:246 | B:246 | 4.0 | 0.018 | -98.3 | 143.9 | NA | NA | NA | ||||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ARG | A:246 | A:246 | 5.0 | 0.022 | -88.1 | 144.3 | 5.0 | 0.022 | 0.0 |
ZN M25 HOH |
8.432 7.991 2.793 |
N CB NE |
ZN N1 O |
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| ARG | B:246 | B:246 | 3.0 | 0.013 | -89.1 | 142.5 | NA | NA | NA | ||||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ARG | A:246 | A:246 | 6.0 | 0.027 | -89.4 | 145.8 | 6.0 | 0.027 | 0.0 |
ZN M28 HOH |
8.379 7.988 2.793 |
N CB O |
ZN N3 O |
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| ARG | B:246 | B:246 | 3.0 | 0.013 | -87.0 | 145.4 | NA | NA | NA | ||||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | ARG | A:246 | A:246 | 6.0 | 0.027 | -95.1 | 145.6 | 6.0 | 0.027 | 0.0 |
ZN M29 HOH |
8.390 8.035 2.750 |
N CB O |
ZN N O |
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| ARG | B:246 | B:246 | 2.0 | 0.009 | -88.5 | 144.7 | NA | NA | NA | ||||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | ARG | A:246 | A:246 | 5.0 | 0.022 | -86.2 | 143.3 | 5.0 | 0.022 | 0.0 |
ZN TOR HOH |
8.189 7.784 2.726 |
N CB O |
ZN NAP O |
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| ARG | B:246 | B:246 | 5.0 | 0.022 | -81.2 | 144.2 | NA | NA | NA | ||||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ARG | A:246 | A:246 | 7.0 | 0.031 | -88.0 | 144.2 | 7.0 | 0.031 | 0.0 |
ZN AZM |
8.158 7.815 |
N CB |
ZN N1 |
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| ARG | B:246 | B:246 | 7.0 | 0.031 | -84.8 | 143.9 | NA | NA | NA | ||||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ARG | A:246 | A:246 | 4.0 | 0.018 | -102.2 | 140.2 | 4.0 | 0.018 | 0.0 |
ZN HOH |
8.430 2.671 |
N O |
ZN O |
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| ARG | B:246 | E:246 | 4.0 | 0.018 | -102.5 | 139.9 | NA | NA | NA | ||||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:246 | A:246 | 5.0 | 0.022 | -86.3 | 144.8 | 5.0 | 0.022 | 0.0 |
ZN 3TV HOH |
8.353 8.140 2.816 |
N CD O |
ZN F17 O |
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| ARG | B:246 | B:246 | 4.0 | 0.018 | -86.8 | 147.2 | NA | NA | NA | ||||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:246 | A:246 | 5.0 | 0.022 | -89.9 | 142.3 | 5.0 | 0.022 | 0.0 |
ZN 3UF HOH |
8.292 7.906 2.771 |
N CB O |
ZN N3 O |
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| ARG | B:246 | B:246 | 5.0 | 0.022 | -86.6 | 140.2 | NA | NA | NA | ||||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:246 | A:246 | 5.0 | 0.022 | -85.7 | 143.7 | 5.0 | 0.022 | 0.0 |
ZN 3UG HOH |
8.349 8.075 2.707 |
N CB O |
ZN N4 O |
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| ARG | B:246 | B:246 | 5.0 | 0.022 | -82.7 | 140.8 | NA | NA | NA | ||||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ARG | A:246 | A:246 | 6.0 | 0.027 | -87.2 | 143.3 | 6.0 | 0.027 | 0.0 |
ZN V14 HOH |
8.285 7.563 2.783 |
N CB O |
ZN F12 O |
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| ARG | B:246 | B:246 | 5.0 | 0.022 | -82.4 | 143.3 | NA | NA | NA | ||||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | ARG | A:246 | A:246 | 4.0 | 0.018 | -94.0 | 136.2 | 4.0 | 0.018 | 0.0 |
ZN EDO HOH |
8.441 8.200 2.890 |
N CB NE |
ZN C1 O |
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| ARG | B:246 | B:246 | 3.0 | 0.013 | -83.3 | 143.4 | NA | NA | NA | ||||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | ARG | A:246 | A:246 | 5.0 | 0.022 | -92.2 | 141.4 | 5.0 | 0.022 | 0.0 |
ZN EDO HOH |
8.477 7.975 2.810 |
N CB NE |
ZN O2 O |
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| ARG | B:246 | B:246 | 5.0 | 0.022 | -90.3 | 146.4 | NA | NA | NA | ||||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | ARG | A:246 | A:246 | 4.0 | 0.018 | -97.8 | 140.0 | 4.0 | 0.018 | 0.0 |
HG CL HG HOH |
8.514 9.076 8.079 2.750 |
N CB N O |
HG CL HG O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | ARG | A:246 | A:246 | 5.0 | 0.022 | -94.8 | 141.5 | 5.0 | 0.022 | 0.0 |
ZN |
8.297 |
N |
ZN |
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| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | ARG | A:242 | A:246 | 3.0 | 0.013 | -88.5 | 140.1 | 3.0 | 0.013 | 0.0 |
ZN PPF HOH |
8.467 8.253 2.761 |
N NH1 O |
ZN O1 O |
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| ARG | B:242 | B:246 | 3.0 | 0.013 | -89.2 | 143.4 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | ARG | A:247 | A:247 | 4.0 | 0.018 | -78.9 | 139.9 | ||