Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86240851 | . | T | A | CCDS6237.1:NM_001128829.2:c.724Atg>Ttg_NP_001122301.1:p.242M>L | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | MET | A:242 | A:241 | 6.0 | 0.032 | -81.4 | 71.0 | 6.0 | 0.032 | 0.0 |
949 HOH |
8.615 3.767 |
CE CG |
F25 O |
|||
| MET | B:242 | B:241 | 6.0 | 0.032 | -88.9 | 69.9 | NA | NA | NA | ||||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | MET | A:242 | A:241 | 7.0 | 0.038 | -79.0 | 78.9 | 7.0 | 0.038 | 0.0 |
HOH |
3.457 |
CG |
O |
|||
| MET | B:242 | B:241 | 7.0 | 0.038 | -81.9 | 83.1 | NA | NA | NA | ||||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | MET | A:242 | A:241 | 10.0 | 0.054 | -79.8 | 86.2 | 10.0 | 0.054 | 0.0 |
HOH |
3.834 |
CG |
O |
|||
| MET | B:242 | B:241 | 9.0 | 0.049 | -77.8 | 86.9 | NA | NA | NA | ||||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | MET | A:242 | A:241 | 7.0 | 0.038 | -76.9 | 80.1 | 7.0 | 0.038 | 0.0 |
HOH |
3.916 |
CG |
O |
|||
| MET | B:242 | B:241 | 7.0 | 0.038 | -77.2 | 84.6 | NA | NA | NA | ||||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | MET | A:242 | A:241 | 10.0 | 0.054 | -78.6 | 80.4 | 10.0 | 0.054 | 0.0 |
GOL HOH |
6.211 4.716 |
O N |
C1 O |
|||
| MET | B:242 | B:241 | 9.0 | 0.049 | -71.8 | 81.2 | NA | NA | NA | ||||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | MET | A:242 | A:241 | 9.0 | 0.049 | -78.2 | 78.4 | 9.0 | 0.049 | 0.0 |
HOH |
3.773 |
CG |
O |
|||
| MET | B:242 | B:241 | 8.0 | 0.043 | -74.4 | 85.9 | NA | NA | NA | ||||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | MET | A:242 | A:241 | 7.0 | 0.038 | -80.0 | 79.6 | 7.0 | 0.038 | 0.0 |
HOH |
6.325 |
N |
O |
|||
| MET | B:242 | B:241 | 7.0 | 0.038 | -77.3 | 80.3 | NA | NA | NA | ||||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | MET | A:242 | A:242 | 7.0 | 0.038 | -84.3 | 81.2 | 7.0 | 0.038 | 0.0 |
HOH |
6.949 |
SD |
O |
|||
| MET | B:242 | B:242 | 6.0 | 0.032 | -75.8 | 83.7 | NA | NA | NA | ||||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | MET | A:242 | A:241 | 8.0 | 0.043 | -81.5 | 81.0 | 8.0 | 0.043 | 0.0 |
HOH |
3.941 |
CA |
O |
|||
| MET | B:242 | B:241 | 9.0 | 0.049 | -82.4 | 81.9 | NA | NA | NA | ||||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | MET | A:242 | A:241 | 8.0 | 0.043 | -83.3 | 78.8 | 8.0 | 0.043 | 0.0 |
HOH |
3.498 |
CG |
O |
|||
| MET | B:242 | B:241 | 7.0 | 0.038 | -81.2 | 81.9 | NA | NA | NA | ||||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | MET | A:242 | A:241 | 7.0 | 0.038 | -104.0 | 80.4 | 7.0 | 0.038 | 0.0 |
HOH |
7.782 |
CG |
O |
|||
| MET | B:242 | B:241 | 7.0 | 0.038 | -96.2 | 82.4 | NA | NA | NA | ||||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 8.0 | 0.043 | -76.9 | 84.1 | 8.0 | 0.043 | 0.0 |
HOH |
4.093 |
CA |
O |
|||
| MET | B:242 | B:241 | 9.0 | 0.049 | -79.3 | 88.3 | NA | NA | NA | ||||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 8.0 | 0.043 | -79.6 | 80.8 | 8.0 | 0.043 | 0.0 |
HOH |
4.061 |
CG |
O |
|||
| MET | B:242 | B:241 | 8.0 | 0.043 | -81.5 | 86.3 | NA | NA | NA | ||||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 8.0 | 0.043 | -78.9 | 85.9 | 8.0 | 0.043 | 0.0 |
HOH |
3.851 |
CA |
O |
|||
| MET | B:242 | B:241 | 8.0 | 0.043 | -79.6 | 86.9 | NA | NA | NA | ||||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 9.0 | 0.049 | -76.9 | 86.2 | 9.0 | 0.049 | 0.0 |
HOH |
3.989 |
CG |
O |
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| MET | B:242 | B:241 | 8.0 | 0.043 | -78.1 | 89.4 | NA | NA | NA | ||||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 8.0 | 0.043 | -77.1 | 78.7 | 8.0 | 0.043 | 0.0 |
HOH |
3.560 |
CG |
O |
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| MET | B:242 | B:241 | 8.0 | 0.043 | -78.3 | 86.3 | NA | NA | NA | ||||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | MET | A:242 | A:241 | 8.0 | 0.043 | -80.6 | 85.6 | 8.0 | 0.043 | 0.0 |
HOH |
4.090 |
CA |
O |
|||
| MET | B:242 | B:241 | 8.0 | 0.043 | -82.5 | 85.9 | NA | NA | NA | ||||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | MET | A:242 | A:241 | 8.0 | 0.043 | -84.4 | 83.5 | 8.0 | 0.043 | 0.0 |
EDO EDO HOH |
3.991 9.881 4.010 |
C CE CG |
O2 C1 O |
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| MET | B:242 | B:241 | 8.0 | 0.043 | -85.2 | 83.7 | NA | NA | NA | ||||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 4.0 | 0.022 | -86.8 | 71.3 | 4.0 | 0.022 | 0.0 |
HOH |
3.840 |
CG |
O |
|||
| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 8.0 | 0.043 | -80.7 | 80.5 | 8.0 | 0.043 | 0.0 |
HOH |
2.699 |
CE |
O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 8.0 | 0.043 | -81.5 | 82.6 | 8.0 | 0.043 | 0.0 |
HOH |
3.617 |
CA |
O |
|||
| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 4.0 | 0.022 | -83.8 | 80.0 | 4.0 | 0.022 | 0.0 |
HOH |
3.720 |
CG |
O |
|||
| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 5.0 | 0.027 | -85.0 | 70.4 | 5.0 | 0.027 | 0.0 |
HOH |
3.914 |
CA |
O |
|||
| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | MET | A:241 | A:241 | 5.0 | 0.027 | -85.9 | 67.4 | 5.0 | 0.027 | 0.0 |
HOH |
6.080 |
N |
O |
|||
| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | MET | A:241 | A:241 | 9.0 | 0.049 | -83.9 | 85.9 | 9.0 | 0.049 | 0.0 |
B30 B30 HOH |
3.107 8.587 4.834 |
CA O N |
O2 O2 O |
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| MET | B:241 | B:241 | 11.0 | 0.059 | -80.6 | 82.5 | NA | NA | NA | ||||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | MET | A:241 | A:241 | 8.0 | 0.043 | -88.8 | 80.7 | 8.0 | 0.043 | 0.0 |
HOH |
4.081 |
CG |
O |
|||
| MET | B:241 | B:241 | 8.0 | 0.043 | -80.4 | 83.0 | NA | NA | NA | ||||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | MET | A:241 | A:241 | 8.0 | 0.043 | -83.3 | 77.2 | 8.0 | 0.043 | 0.0 |
HOH |
3.921 |
C |
O |
|||
| MET | B:241 | B:241 | 9.0 | 0.049 | -82.9 | 82.1 | NA | NA | NA | ||||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | MET | A:241 | A:241 | 8.0 | 0.043 | -81.3 | 78.9 | 8.0 | 0.043 | 0.0 |
HOH |
3.841 |
CG |
O |
|||
| MET | B:241 | B:241 | 7.0 | 0.038 | -83.5 | 77.4 | NA | NA | NA | ||||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | MET | A:241 | A:241 | 9.0 | 0.049 | -85.4 | 71.6 | 9.0 | 0.049 | 0.0 |
HOH |
3.695 |
CG |
O |
|||
| MET | B:241 | B:241 | 7.0 | 0.038 | -86.8 | 75.5 | NA | NA | NA | ||||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | MET | A:241 | A:241 | 8.0 | 0.043 | -85.9 | 91.2 | 8.0 | 0.043 | 0.0 |
TOR HOH |
8.191 4.325 |
SD CB |
CAD O |
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| MET | B:241 | B:241 | 7.0 | 0.038 | -83.4 | 89.3 | NA | NA | NA | ||||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | MET | A:241 | A:241 | 5.0 | 0.027 | -73.3 | 97.8 | 5.0 | 0.027 | 0.0 | |||||||
| MET | B:241 | B:241 | 5.0 | 0.027 | -74.0 | 99.2 | NA | NA | NA | ||||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | MET | A:241 | A:241 | 8.0 | 0.043 | -80.7 | 84.2 | 8.0 | 0.043 | 0.0 |
HOH |
6.872 |
CG |
O |
|||
| MET | B:241 | E:241 | 7.0 | 0.038 | -80.4 | 84.4 | NA | NA | NA | ||||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | MET | A:241 | A:241 | 7.0 | 0.038 | -78.5 | 79.5 | 7.0 | 0.038 | 0.0 |
HOH |
3.949 |
C |
O |
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| MET | B:241 | B:241 | 8.0 | 0.043 | -82.5 | 83.5 | NA | NA | NA | ||||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | MET | A:241 | A:241 | 8.0 | 0.043 | -81.4 | 85.0 | 8.0 | 0.043 | 0.0 |
HOH |
3.501 |
CG |
O |
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| MET | B:241 | B:241 | 8.0 | 0.043 | -86.1 | 91.8 | NA | NA | NA | ||||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | MET | A:241 | A:241 | 8.0 | 0.043 | -88.4 | 88.5 | 8.0 | 0.043 | 0.0 |
HOH |
4.050 |
CG |
O |
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| MET | B:241 | B:241 | 9.0 | 0.049 | -85.6 | 86.8 | NA | NA | NA | ||||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | MET | A:241 | A:241 | 8.0 | 0.043 | -88.6 | 88.3 | 8.0 | 0.043 | 0.0 |
V14 HOH |
9.876 3.895 |
SD C |
O17 O |
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| MET | B:241 | B:241 | 8.0 | 0.043 | -80.8 | 86.5 | NA | NA | NA | ||||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | MET | A:241 | A:241 | 9.0 | 0.049 | -82.1 | 75.4 | 9.0 | 0.049 | 0.0 |
HOH |
4.485 |
N |
O |
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| MET | B:241 | B:241 | 10.0 | 0.054 | -86.7 | 93.2 | NA | NA | NA | ||||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | MET | A:241 | A:241 | 9.0 | 0.049 | -81.2 | 78.0 | 9.0 | 0.049 | 0.0 |
ZN CL ZN HOH |
9.398 9.104 7.982 4.161 |
SD SD C C |
ZN CL ZN O |
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| MET | B:241 | B:241 | 9.0 | 0.049 | -88.2 | 90.7 | NA | NA | NA | ||||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | MET | A:241 | A:241 | 4.0 | 0.022 | -91.3 | 70.0 | 4.0 | 0.022 | 0.0 |
HG HOH |
9.595 2.373 |
O CG |
HG O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | MET | A:241 | A:241 | 6.0 | 0.032 | -82.0 | 74.6 | 6.0 | 0.032 | 0.0 | |||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | MET | A:237 | A:241 | 8.0 | 0.043 | -84.6 | 84.0 | 8.0 | 0.043 | 0.0 |
HOH |
4.031 |
CB |
O |
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| MET | B:237 | B:241 | 9.0 | 0.049 | -84.1 | 81.6 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | MET | A:242 | A:242 | 8.0 | 0.043 | -81.7 | 74.8 | ||