Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86240861 | . | G | A | CCDS6237.1:NM_001128829.2:c.714aaC>aaT_NP_001122301.1:p.238N>N | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | ASN | A:238 | A:237 | 147.0 | 0.919 | -66.3 | 140.9 | 147.0 | 0.919 | 0.0 |
HOH |
2.641 |
N |
O |
|||
ASN | B:238 | B:237 | 133.0 | 0.831 | -59.3 | 135.8 | NA | NA | NA | ||||||||||||||
6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ASN | A:238 | A:237 | 148.0 | 0.925 | -59.7 | 131.0 | 148.0 | 0.925 | 0.0 |
HOH |
2.472 |
O |
O |
|||
ASN | B:238 | B:237 | 141.0 | 0.881 | -64.1 | 136.7 | NA | NA | NA | ||||||||||||||
6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ASN | A:238 | A:237 | 149.0 | 0.931 | -65.4 | 137.9 | 149.0 | 0.931 | 0.0 |
HOH |
2.631 |
O |
O |
|||
ASN | B:238 | B:237 | 149.0 | 0.931 | -63.0 | 131.8 | NA | NA | NA | ||||||||||||||
6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ASN | A:238 | A:237 | 148.0 | 0.925 | -56.5 | 131.0 | 148.0 | 0.925 | 0.0 |
HOH |
2.640 |
OD1 |
O |
|||
ASN | B:238 | B:237 | 141.0 | 0.881 | -62.3 | 135.5 | NA | NA | NA | ||||||||||||||
6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ASN | A:238 | A:237 | 138.0 | 0.863 | -70.5 | 144.8 | 138.0 | 0.863 | 0.0 |
HOH |
2.573 |
O |
O |
|||
ASN | B:238 | B:237 | 149.0 | 0.931 | -62.1 | 132.7 | NA | NA | NA | ||||||||||||||
6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ASN | A:238 | A:237 | 150.0 | 0.938 | -50.6 | 126.7 | 150.0 | 0.938 | 0.0 |
HOH |
2.517 |
OD1 |
O |
|||
ASN | B:238 | B:237 | 148.0 | 0.925 | -67.0 | 135.6 | NA | NA | NA | ||||||||||||||
6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | ASN | A:238 | A:237 | 147.0 | 0.919 | -63.0 | 140.3 | 147.0 | 0.919 | 0.0 |
HOH |
4.538 |
O |
O |
|||
ASN | B:238 | B:237 | 143.0 | 0.894 | -66.8 | 131.2 | NA | NA | NA | ||||||||||||||
6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | ASN | A:238 | A:238 | 148.0 | 0.925 | -54.5 | 135.0 | 148.0 | 0.925 | 0.0 |
HOH |
5.780 |
O |
O |
|||
ASN | B:238 | B:238 | 140.0 | 0.875 | -67.6 | 134.9 | NA | NA | NA | ||||||||||||||
6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ASN | A:238 | A:237 | 148.0 | 0.925 | -57.4 | 135.5 | 148.0 | 0.925 | 0.0 |
HOH |
2.702 |
O |
O |
|||
ASN | B:238 | B:237 | 143.0 | 0.894 | -56.6 | 136.7 | NA | NA | NA | ||||||||||||||
6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ASN | A:238 | A:237 | 150.0 | 0.938 | -57.3 | 135.4 | 150.0 | 0.938 | 0.0 |
HOH |
2.678 |
O |
O |
|||
ASN | B:238 | B:237 | 143.0 | 0.894 | -63.8 | 132.2 | NA | NA | NA | ||||||||||||||
6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | ASN | A:238 | A:237 | 142.0 | 0.887 | -69.9 | 132.9 | 142.0 | 0.887 | 0.0 |
HOH |
4.639 |
ND2 |
O |
|||
ASN | B:238 | B:237 | 153.0 | 0.956 | -65.5 | 117.8 | NA | NA | NA | ||||||||||||||
6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 147.0 | 0.919 | -58.8 | 134.5 | 147.0 | 0.919 | 0.0 |
HOH |
2.497 |
O |
O |
|||
ASN | B:238 | B:237 | 142.0 | 0.887 | -62.2 | 136.5 | NA | NA | NA | ||||||||||||||
6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 147.0 | 0.919 | -57.9 | 136.9 | 147.0 | 0.919 | 0.0 |
HOH |
2.635 |
O |
O |
|||
ASN | B:238 | B:237 | 139.0 | 0.869 | -61.8 | 137.6 | NA | NA | NA | ||||||||||||||
6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 146.0 | 0.912 | -58.2 | 129.8 | 146.0 | 0.912 | 0.0 |
HOH |
2.583 |
O |
O |
|||
ASN | B:238 | B:237 | 141.0 | 0.881 | -63.5 | 139.3 | NA | NA | NA | ||||||||||||||
6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 148.0 | 0.925 | -57.7 | 136.8 | 148.0 | 0.925 | 0.0 |
HOH |
2.729 |
O |
O |
|||
ASN | B:238 | B:237 | 142.0 | 0.887 | -62.7 | 141.4 | NA | NA | NA | ||||||||||||||
6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 145.0 | 0.906 | -59.6 | 133.2 | 145.0 | 0.906 | 0.0 |
HOH |
2.624 |
O |
O |
|||
ASN | B:238 | B:237 | 140.0 | 0.875 | -63.6 | 142.6 | NA | NA | NA | ||||||||||||||
6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ASN | A:238 | A:237 | 146.0 | 0.912 | -56.8 | 132.4 | 146.0 | 0.912 | 0.0 |
HOH |
2.642 |
O |
O |
|||
ASN | B:238 | B:237 | 138.0 | 0.863 | -58.7 | 137.8 | NA | NA | NA | ||||||||||||||
7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ASN | A:238 | A:237 | 143.0 | 0.894 | -45.6 | 136.1 | 143.0 | 0.894 | 0.0 |
PEG HOH |
9.601 2.726 |
N O |
O2 O |
|||
ASN | B:238 | B:237 | 151.0 | 0.944 | -55.5 | 148.7 | NA | NA | NA | ||||||||||||||
1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 129.0 | 0.806 | -68.9 | 140.1 | 129.0 | 0.806 | 0.0 |
HOH |
3.279 |
OD1 |
O |
|||
1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 148.0 | 0.925 | -67.1 | 143.3 | 148.0 | 0.925 | 0.0 |
HOH |
3.028 |
O |
O |
|||
1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 128.0 | 0.8 | -68.7 | 142.9 | 128.0 | 0.8 | 0.0 |
HOH |
2.836 |
OD1 |
O |
|||
1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 127.0 | 0.794 | -62.7 | 144.8 | 127.0 | 0.794 | 0.0 |
HOH |
2.907 |
ND2 |
O |
|||
1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 125.0 | 0.781 | -64.7 | 147.3 | 125.0 | 0.781 | 0.0 |
HOH |
2.584 |
OD1 |
O |
|||
1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ASN | A:237 | A:237 | 126.0 | 0.787 | -73.8 | 136.4 | 126.0 | 0.787 | 0.0 |
HOH |
3.459 |
ND2 |
O |
|||
2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | ASN | A:237 | A:237 | 139.0 | 0.869 | -59.7 | 137.3 | 139.0 | 0.869 | 0.0 |
B30 HOH |
9.805 2.711 |
ND2 O |
O7 O |
|||
ASN | B:237 | B:237 | 139.0 | 0.869 | -58.0 | 136.8 | NA | NA | NA | ||||||||||||||
2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | ASN | A:237 | A:237 | 144.0 | 0.9 | -67.1 | 157.5 | 144.0 | 0.9 | 0.0 |
HOH |
2.393 |
CB |
O |
|||
ASN | B:237 | B:237 | 150.0 | 0.938 | -62.6 | 140.2 | NA | NA | NA | ||||||||||||||
2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ASN | A:237 | A:237 | 144.0 | 0.9 | -59.5 | 132.6 | 144.0 | 0.9 | 0.0 |
HOH |
2.669 |
O |
O |
|||
ASN | B:237 | B:237 | 141.0 | 0.881 | -57.4 | 139.9 | NA | NA | NA | ||||||||||||||
2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ASN | A:237 | A:237 | 148.0 | 0.925 | -60.8 | 134.3 | 148.0 | 0.925 | 0.0 |
HOH |
2.648 |
O |
O |
|||
ASN | B:237 | B:237 | 140.0 | 0.875 | -62.1 | 139.3 | NA | NA | NA | ||||||||||||||
2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | ASN | A:237 | A:237 | 147.0 | 0.919 | -67.1 | 137.8 | 147.0 | 0.919 | 0.0 |
HOH |
2.635 |
O |
O |
|||
ASN | B:237 | B:237 | 138.0 | 0.863 | -61.9 | 133.4 | NA | NA | NA | ||||||||||||||
3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | ASN | A:237 | A:237 | 141.0 | 0.881 | -64.2 | 131.8 | 141.0 | 0.881 | 0.0 |
HOH |
2.758 |
O |
O |
|||
ASN | B:237 | B:237 | 138.0 | 0.863 | -61.8 | 132.3 | NA | NA | NA | ||||||||||||||
3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ASN | A:237 | A:237 | 102.0 | 0.637 | -56.8 | -161.0 | 102.0 | 0.637 | 0.0 | |||||||
ASN | B:237 | B:237 | 101.0 | 0.631 | -55.3 | -160.4 | NA | NA | NA | ||||||||||||||
3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ASN | A:237 | A:237 | 152.0 | 0.95 | -58.4 | 133.1 | 152.0 | 0.95 | 0.0 |
HOH |
5.714 |
O |
O |
|||
ASN | B:237 | E:237 | 153.0 | 0.956 | -58.7 | 132.7 | NA | NA | NA | ||||||||||||||
4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ASN | A:237 | A:237 | 148.0 | 0.925 | -55.0 | 131.9 | 148.0 | 0.925 | 0.0 |
HOH |
2.651 |
O |
O |
|||
ASN | B:237 | B:237 | 141.0 | 0.881 | -65.1 | 142.1 | NA | NA | NA | ||||||||||||||
4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ASN | A:237 | A:237 | 152.0 | 0.95 | -67.6 | 141.6 | 152.0 | 0.95 | 0.0 |
HOH |
2.378 |
O |
O |
|||
ASN | B:237 | B:237 | 145.0 | 0.906 | -62.7 | 133.1 | NA | NA | NA | ||||||||||||||
4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ASN | A:237 | A:237 | 152.0 | 0.95 | -60.8 | 132.3 | 152.0 | 0.95 | 0.0 |
HOH |
2.545 |
O |
O |
|||
ASN | B:237 | B:237 | 139.0 | 0.869 | -59.4 | 139.9 | NA | NA | NA | ||||||||||||||
5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ASN | A:237 | A:237 | 145.0 | 0.906 | -62.6 | 141.2 | 145.0 | 0.906 | 0.0 |
HOH |
2.679 |
O |
O |
|||
ASN | B:237 | B:237 | 140.0 | 0.875 | -56.5 | 137.4 | NA | NA | NA | ||||||||||||||
1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | ASN | A:237 | A:237 | 79.0 | NA | -52.1 | 138.3 | 79.0 | NA | NA |
HOH |
6.405 |
O |
O |
|||
ASN | B:237 | B:237 | 148.0 | 0.925 | -68.9 | 141.3 | NA | NA | NA | ||||||||||||||
1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | ASN | A:237 | A:237 | 144.0 | 0.9 | -72.2 | 146.6 | 144.0 | 0.9 | 0.0 |
HOH |
2.681 |
O |
O |
|||
ASN | B:237 | B:237 | 149.0 | 0.931 | -56.9 | 139.1 | NA | NA | NA | ||||||||||||||
1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | ASN | A:237 | A:237 | 125.0 | 0.781 | -77.0 | 141.1 | 125.0 | 0.781 | 0.0 |
HOH |
2.663 |
OD1 |
O |
|||
2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | ASN | A:237 | A:237 | 124.0 | 0.775 | -65.0 | 149.7 | 124.0 | 0.775 | 0.0 | |||||||
2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | ASN | A:233 | A:237 | 150.0 | 0.938 | -61.8 | 145.9 | 150.0 | 0.938 | 0.0 |
HOH |
2.355 |
CB |
O |
|||
ASN | B:233 | B:237 | 154.0 | 0.963 | -58.1 | 129.7 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | ASN | A:238 | A:238 | 147.0 | 0.919 | -55.6 | 133.7 |