Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86242000 | . | G | A | CCDS6237.1:NM_001128829.2:c.587cCt>cTt_NP_001122301.1:p.196P>L | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | PRO | A:196 | A:195 | 66.0 | 0.455 | E | -85.8 | 125.5 | 66.0 | 0.455 | 0.0 |
HOH |
3.539 |
C |
O |
||
| PRO | B:196 | B:195 | 63.0 | 0.434 | E | -80.5 | 128.0 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | PRO | A:196 | A:195 | 64.0 | 0.441 | E | -83.3 | 125.1 | 64.0 | 0.441 | 0.0 |
HOH |
3.362 |
CA |
O |
||
| PRO | B:196 | B:195 | 58.0 | 0.4 | E | -89.7 | 129.8 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | PRO | A:196 | A:195 | 61.0 | 0.421 | E | -81.2 | 124.0 | 61.0 | 0.421 | 0.0 |
HOH |
3.369 |
CB |
O |
||
| PRO | B:196 | B:195 | 60.0 | 0.414 | E | -84.6 | 128.5 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | PRO | A:196 | A:195 | 64.0 | 0.441 | E | -80.5 | 126.6 | 64.0 | 0.441 | 0.0 |
HOH |
3.334 |
CA |
O |
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| PRO | B:196 | B:195 | 60.0 | 0.414 | E | -82.1 | 126.7 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | PRO | A:196 | A:195 | 61.0 | 0.421 | E | -74.3 | 125.3 | 61.0 | 0.421 | 0.0 |
HOH |
3.312 |
CD |
O |
||
| PRO | B:196 | B:195 | 59.0 | 0.407 | E | -82.2 | 129.3 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | PRO | A:196 | A:195 | 63.0 | 0.434 | E | -81.5 | 126.4 | 63.0 | 0.434 | 0.0 |
HOH |
3.464 |
CA |
O |
||
| PRO | B:196 | B:195 | 59.0 | 0.407 | E | -86.7 | 128.6 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | PRO | A:196 | A:195 | 66.0 | 0.455 | E | -84.2 | 124.1 | 66.0 | 0.455 | 0.0 |
HOH |
3.424 |
CB |
O |
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| PRO | B:196 | B:195 | 61.0 | 0.421 | E | -87.2 | 126.7 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | PRO | A:196 | A:196 | 60.0 | 0.414 | E | -86.2 | 127.8 | 60.0 | 0.414 | 0.0 |
HOH |
3.515 |
C |
O |
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| PRO | B:196 | B:196 | 55.0 | 0.379 | E | -87.7 | 129.5 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | PRO | A:196 | A:195 | 63.0 | 0.434 | E | -82.7 | 123.3 | 63.0 | 0.434 | 0.0 |
HOH |
3.381 |
CB |
O |
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| PRO | B:196 | B:195 | 61.0 | 0.421 | E | -82.4 | 125.6 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | PRO | A:196 | A:195 | 61.0 | 0.421 | E | -81.7 | 126.7 | 61.0 | 0.421 | 0.0 |
HOH |
3.516 |
CB |
O |
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| PRO | B:196 | B:195 | 59.0 | 0.407 | E | -81.4 | 124.9 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | PRO | A:196 | A:195 | 58.0 | 0.4 | E | -79.5 | 117.3 | 58.0 | 0.4 | 0.0 |
HOH |
7.772 |
CG |
O |
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| PRO | B:196 | B:195 | 57.0 | 0.393 | E | -67.5 | 126.0 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 65.0 | 0.448 | E | -83.4 | 128.8 | 65.0 | 0.448 | 0.0 |
HOH |
3.269 |
CB |
O |
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| PRO | B:196 | B:195 | 63.0 | 0.434 | E | -83.6 | 128.7 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 64.0 | 0.441 | E | -82.0 | 128.6 | 64.0 | 0.441 | 0.0 |
HOH |
3.342 |
CB |
O |
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| PRO | B:196 | B:195 | 62.0 | 0.428 | E | -82.8 | 129.9 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 64.0 | 0.441 | E | -83.8 | 126.9 | 64.0 | 0.441 | 0.0 |
HOH |
3.265 |
CB |
O |
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| PRO | B:196 | B:195 | 62.0 | 0.428 | E | -84.0 | 129.6 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 62.0 | 0.428 | E | -81.8 | 129.0 | 62.0 | 0.428 | 0.0 |
HOH |
3.315 |
CB |
O |
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| PRO | B:196 | B:195 | 63.0 | 0.434 | E | -84.6 | 129.4 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 60.0 | 0.414 | E | -84.1 | 128.2 | 60.0 | 0.414 | 0.0 |
HOH |
3.359 |
CB |
O |
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| PRO | B:196 | B:195 | 63.0 | 0.434 | E | -84.1 | 128.4 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | PRO | A:196 | A:195 | 61.0 | 0.421 | E | -82.6 | 127.8 | 61.0 | 0.421 | 0.0 |
HOH |
3.289 |
CB |
O |
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| PRO | B:196 | B:195 | 62.0 | 0.428 | E | -83.9 | 129.3 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | PRO | A:196 | A:195 | 57.0 | 0.393 | E | -84.9 | 125.6 | 57.0 | 0.393 | 0.0 |
EDO HOH |
7.477 3.428 |
O CB |
O2 O |
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| PRO | B:196 | B:195 | 65.0 | 0.448 | E | -83.5 | 128.2 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 63.0 | 0.434 | E | -81.7 | 127.0 | 63.0 | 0.434 | 0.0 |
HOH |
3.318 |
CD |
O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 64.0 | 0.441 | E | -82.5 | 134.6 | 64.0 | 0.441 | 0.0 |
HOH |
3.366 |
CB |
O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 62.0 | 0.428 | E | -81.3 | 131.6 | 62.0 | 0.428 | 0.0 |
HOH |
3.432 |
CD |
O |
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| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 66.0 | 0.455 | E | -86.9 | 130.6 | 66.0 | 0.455 | 0.0 |
HOH |
3.413 |
C |
O |
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| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 62.0 | 0.428 | E | -79.5 | 128.4 | 62.0 | 0.428 | 0.0 |
AUC HOH |
9.167 3.296 |
CG CD |
C2 O |
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| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | PRO | A:195 | A:195 | 58.0 | 0.4 | E | -72.2 | 115.4 | 58.0 | 0.4 | 0.0 |
HOH |
2.774 |
CB |
O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | PRO | A:195 | A:195 | 64.0 | 0.441 | E | -82.0 | 118.8 | 64.0 | 0.441 | 0.0 |
HOH |
3.436 |
CB |
O |
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| PRO | B:195 | B:195 | 64.0 | 0.441 | E | -82.7 | 122.6 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | PRO | A:195 | A:195 | 60.0 | 0.414 | E | -76.8 | 129.8 | 60.0 | 0.414 | 0.0 |
HOH |
3.464 |
CD |
O |
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| PRO | B:195 | B:195 | 56.0 | 0.386 | E | -77.2 | 126.6 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | PRO | A:195 | A:195 | 62.0 | 0.428 | E | -79.1 | 121.7 | 62.0 | 0.428 | 0.0 |
HOH |
3.487 |
CB |
O |
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| PRO | B:195 | B:195 | 64.0 | 0.441 | E | -79.8 | 122.2 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | PRO | A:195 | A:195 | 63.0 | 0.434 | E | -80.6 | 125.7 | 63.0 | 0.434 | 0.0 |
HOH |
3.369 |
CB |
O |
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| PRO | B:195 | B:195 | 62.0 | 0.428 | E | -84.1 | 125.4 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | PRO | A:195 | A:195 | 63.0 | 0.434 | E | -77.8 | 120.0 | 63.0 | 0.434 | 0.0 |
HOH |
3.360 |
CB |
O |
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| PRO | B:195 | B:195 | 63.0 | 0.434 | E | -84.7 | 124.8 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | PRO | A:195 | A:195 | 62.0 | 0.428 | E | -80.1 | 122.6 | 62.0 | 0.428 | 0.0 |
HOH |
3.395 |
CB |
O |
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| PRO | B:195 | B:195 | 58.0 | 0.4 | E | -80.1 | 125.0 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | PRO | A:195 | A:195 | 54.0 | 0.372 | E | -75.3 | 130.6 | 54.0 | 0.372 | 0.0 | ||||||
| PRO | B:195 | B:195 | 56.0 | 0.386 | E | -75.2 | 133.7 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | PRO | A:195 | A:195 | 64.0 | 0.441 | E | -66.6 | 117.0 | 64.0 | 0.441 | 0.0 |
HOH |
3.687 |
CD |
O |
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| PRO | B:195 | E:195 | 63.0 | 0.434 | E | -66.5 | 117.1 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PRO | A:195 | A:195 | 58.0 | 0.4 | E | -85.9 | 127.4 | 58.0 | 0.4 | 0.0 |
HOH |
3.304 |
CB |
O |
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| PRO | B:195 | B:195 | 61.0 | 0.421 | E | -84.4 | 126.5 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PRO | A:195 | A:195 | 64.0 | 0.441 | E | -81.0 | 126.3 | 64.0 | 0.441 | 0.0 |
HOH |
3.380 |
CB |
O |
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| PRO | B:195 | B:195 | 57.0 | 0.393 | E | -86.8 | 129.1 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | PRO | A:195 | A:195 | 61.0 | 0.421 | E | -78.2 | 125.9 | 61.0 | 0.421 | 0.0 |
HOH |
3.490 |
CB |
O |
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| PRO | B:195 | B:195 | 56.0 | 0.386 | E | -90.7 | 131.6 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | PRO | A:195 | A:195 | 60.0 | 0.414 | E | -82.7 | 124.0 | 60.0 | 0.414 | 0.0 |
HOH |
3.304 |
CB |
O |
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| PRO | B:195 | B:195 | 58.0 | 0.4 | E | -81.8 | 128.0 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | PRO | A:195 | A:195 | 68.0 | 0.469 | E | -83.7 | 131.0 | 68.0 | 0.469 | 0.0 |
HOH |
3.485 |
CD |
O |
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| PRO | B:195 | B:195 | 56.0 | 0.386 | E | -79.6 | 140.4 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | PRO | A:195 | A:195 | 61.0 | 0.421 | E | -77.0 | 124.3 | 61.0 | 0.421 | 0.0 |
HOH |
3.389 |
C |
O |
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| PRO | B:195 | B:195 | 55.0 | 0.379 | E | -73.5 | 124.1 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | PRO | A:195 | A:195 | 63.0 | 0.434 | E | -80.4 | 130.0 | 63.0 | 0.434 | 0.0 |
HOH |
3.802 |
CD |
O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | PRO | A:195 | A:195 | 63.0 | 0.434 | E | -81.5 | 129.4 | 63.0 | 0.434 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | PRO | A:191 | A:195 | 60.0 | 0.414 | E | -80.4 | 124.2 | 60.0 | 0.414 | 0.0 |
HOH |
3.219 |
CB |
O |
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| PRO | B:191 | B:195 | 60.0 | 0.414 | E | -78.9 | 126.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | PRO | A:196 | A:196 | 69.0 | 0.476 | E | -76.6 | 132.1 | |