Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86244732 | . | G | A | CCDS6237.1:NM_001128829.2:c.500gCa>gTa_NP_001122301.1:p.167A>V | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | ALA | A:167 | A:166 | 40.0 | 0.348 | G | -88.6 | -7.1 | 40.0 | 0.348 | 0.0 |
HOH |
2.893 |
O |
O |
||
| ALA | B:167 | B:166 | 68.0 | 0.591 | T | -96.0 | -4.2 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ALA | A:167 | A:166 | 32.0 | 0.278 | G | -89.9 | -3.9 | 32.0 | 0.278 | 0.0 |
HOH |
2.729 |
O |
O |
||
| ALA | B:167 | B:166 | 29.0 | 0.252 | G | -85.5 | -5.7 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:167 | A:166 | 31.0 | 0.27 | G | -92.8 | -7.8 | 31.0 | 0.27 | 0.0 |
GOL HOH |
7.132 2.740 |
O O |
O3 O |
||
| ALA | B:167 | B:166 | 30.0 | 0.261 | G | -90.0 | -7.9 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:167 | A:166 | 32.0 | 0.278 | G | -96.7 | -6.7 | 32.0 | 0.278 | 0.0 |
HOH |
2.642 |
O |
O |
||
| ALA | B:167 | B:166 | 29.0 | 0.252 | G | -90.0 | -6.3 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:167 | A:166 | 37.0 | 0.322 | G | -83.1 | -14.7 | 37.0 | 0.322 | 0.0 |
HOH |
3.128 |
C |
O |
||
| ALA | B:167 | B:166 | 33.0 | 0.287 | G | -87.9 | -8.3 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:167 | A:166 | 31.0 | 0.27 | G | -85.8 | -5.6 | 31.0 | 0.27 | 0.0 |
HOH |
3.256 |
CB |
O |
||
| ALA | B:167 | B:166 | 29.0 | 0.252 | G | -85.4 | -7.8 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | ALA | A:167 | A:166 | 31.0 | 0.27 | G | -93.4 | -0.8 | 31.0 | 0.27 | 0.0 |
HOH |
3.126 |
C |
O |
||
| ALA | B:167 | B:166 | 31.0 | 0.27 | G | -86.4 | -8.6 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | ALA | A:167 | A:167 | 31.0 | 0.27 | G | -86.4 | -8.2 | 31.0 | 0.27 | 0.0 |
HOH |
3.214 |
C |
O |
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| ALA | B:167 | B:167 | 29.0 | 0.252 | G | -95.8 | -4.2 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ALA | A:167 | A:166 | 33.0 | 0.287 | G | -92.2 | -5.9 | 33.0 | 0.287 | 0.0 |
HOH |
2.736 |
O |
O |
||
| ALA | B:167 | B:166 | 29.0 | 0.252 | G | -95.8 | -5.1 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ALA | A:167 | A:166 | 33.0 | 0.287 | G | -89.0 | -6.5 | 33.0 | 0.287 | 0.0 |
HOH |
2.699 |
O |
O |
||
| ALA | B:167 | B:166 | 28.0 | 0.243 | G | -87.6 | -7.7 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -100.4 | -2.8 | 30.0 | 0.261 | 0.0 |
HOH |
9.379 |
O |
O |
||
| ALA | B:167 | B:166 | 29.0 | 0.252 | G | -76.2 | -16.6 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -91.8 | -7.1 | 30.0 | 0.261 | 0.0 |
HOH |
2.940 |
O |
O |
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| ALA | B:167 | B:166 | 30.0 | 0.261 | G | -91.2 | -6.5 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -95.2 | -5.3 | 30.0 | 0.261 | 0.0 |
HOH |
2.702 |
O |
O |
||
| ALA | B:167 | B:166 | 30.0 | 0.261 | G | -87.8 | -8.6 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 32.0 | 0.278 | G | -92.1 | -6.1 | 32.0 | 0.278 | 0.0 |
HOH |
3.146 |
C |
O |
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| ALA | B:167 | B:166 | 31.0 | 0.27 | G | -91.5 | -7.6 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -89.8 | -8.5 | 30.0 | 0.261 | 0.0 |
HOH |
2.846 |
O |
O |
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| ALA | B:167 | B:166 | 31.0 | 0.27 | G | -91.6 | -5.7 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -93.9 | -7.9 | 30.0 | 0.261 | 0.0 |
HOH |
2.737 |
O |
O |
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| ALA | B:167 | B:166 | 30.0 | 0.261 | G | -90.7 | -5.5 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:167 | A:166 | 32.0 | 0.278 | G | -92.9 | -6.2 | 32.0 | 0.278 | 0.0 |
HOH |
2.714 |
O |
O |
||
| ALA | B:167 | B:166 | 31.0 | 0.27 | G | -92.4 | -4.8 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ALA | A:167 | A:166 | 30.0 | 0.261 | G | -91.8 | -3.6 | 30.0 | 0.261 | 0.0 |
HOH |
2.727 |
O |
O |
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| ALA | B:167 | B:166 | 31.0 | 0.27 | G | -89.1 | -8.0 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 61.0 | 0.53 | G | -82.5 | -6.2 | 61.0 | 0.53 | 0.0 |
HOH |
5.972 |
O |
O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 60.0 | 0.522 | G | -79.5 | -10.0 | 60.0 | 0.522 | 0.0 |
HOH |
2.805 |
O |
O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 62.0 | 0.539 | G | -93.3 | -5.6 | 62.0 | 0.539 | 0.0 |
HOH |
5.572 |
N |
O |
||
| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 59.0 | 0.513 | G | -88.4 | -1.9 | 59.0 | 0.513 | 0.0 |
HOH |
2.632 |
O |
O |
||
| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 62.0 | 0.539 | G | -84.1 | -9.4 | 62.0 | 0.539 | 0.0 |
HOH |
3.245 |
O |
O |
||
| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:166 | A:166 | 61.0 | 0.53 | G | -85.6 | -7.2 | 61.0 | 0.53 | 0.0 |
HOH |
3.793 |
N |
O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | ALA | A:166 | A:166 | 31.0 | 0.27 | G | -94.6 | -8.5 | 31.0 | 0.27 | 0.0 |
HOH |
2.867 |
O |
O |
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| ALA | B:166 | B:166 | 33.0 | 0.287 | G | -96.3 | -5.6 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | ALA | A:166 | A:166 | 28.0 | 0.243 | G | -79.9 | -12.7 | 28.0 | 0.243 | 0.0 |
HOH |
2.885 |
O |
O |
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| ALA | B:166 | B:166 | 29.0 | 0.252 | G | -91.4 | -6.8 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ALA | A:166 | A:166 | 30.0 | 0.261 | G | -95.3 | -9.2 | 30.0 | 0.261 | 0.0 |
HOH |
2.831 |
O |
O |
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| ALA | B:166 | B:166 | 31.0 | 0.27 | G | -94.4 | -9.2 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ALA | A:166 | A:166 | 32.0 | 0.278 | G | -99.1 | -6.7 | 32.0 | 0.278 | 0.0 |
HOH |
2.693 |
O |
O |
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| ALA | B:166 | B:166 | 30.0 | 0.261 | G | -92.4 | -6.9 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | ALA | A:166 | A:166 | 31.0 | 0.27 | G | -96.7 | -16.6 | 31.0 | 0.27 | 0.0 |
HOH |
2.953 |
O |
O |
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| ALA | B:166 | B:166 | 30.0 | 0.261 | G | -95.8 | -11.6 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | ALA | A:166 | A:166 | 30.0 | 0.261 | G | -102.1 | -7.3 | 30.0 | 0.261 | 0.0 |
HOH |
2.892 |
O |
O |
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| ALA | B:166 | B:166 | 30.0 | 0.261 | G | -95.1 | -8.4 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ALA | A:166 | A:166 | 27.0 | 0.235 | G | -102.3 | 0.3 | 27.0 | 0.235 | 0.0 | ||||||
| ALA | B:166 | B:166 | 28.0 | 0.243 | G | -98.9 | 0.5 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ALA | A:166 | A:166 | 41.0 | 0.357 | G | -97.3 | -8.7 | 41.0 | 0.357 | 0.0 | ||||||
| ALA | B:166 | E:166 | 41.0 | 0.357 | G | -97.8 | -8.5 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:166 | A:166 | 31.0 | 0.27 | G | -88.2 | -7.1 | 31.0 | 0.27 | 0.0 |
PEG HOH |
2.868 3.186 |
O CB |
C3 O |
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| ALA | B:166 | B:166 | 34.0 | 0.296 | G | -90.3 | -3.2 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:166 | A:166 | 29.0 | 0.252 | G | -89.8 | -6.7 | 29.0 | 0.252 | 0.0 |
HOH |
2.951 |
O |
O |
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| ALA | B:166 | B:166 | 31.0 | 0.27 | G | -88.8 | -4.4 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:166 | A:166 | 30.0 | 0.261 | G | -88.1 | -10.2 | 30.0 | 0.261 | 0.0 |
HOH |
2.773 |
O |
O |
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| ALA | B:166 | B:166 | 29.0 | 0.252 | G | -85.9 | -7.3 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ALA | A:166 | A:166 | 27.0 | 0.235 | G | -89.2 | -10.4 | 27.0 | 0.235 | 0.0 |
HOH |
2.754 |
O |
O |
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| ALA | B:166 | B:166 | 30.0 | 0.261 | G | -84.9 | -5.3 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | ALA | A:166 | A:166 | 49.0 | 0.426 | G | -92.9 | -16.1 | 49.0 | 0.426 | 0.0 |
HOH |
3.018 |
N |
O |
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| ALA | B:166 | B:166 | 30.0 | 0.261 | G | -90.0 | -12.8 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | ALA | A:166 | A:166 | 32.0 | 0.278 | G | -85.5 | -7.7 | 32.0 | 0.278 | 0.0 |
HOH |
2.700 |
O |
O |
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| ALA | B:166 | B:166 | 29.0 | 0.252 | G | -79.5 | -9.8 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | ALA | A:166 | A:166 | 62.0 | 0.539 | G | -82.5 | -8.0 | 62.0 | 0.539 | 0.0 |
HOH |
3.378 |
CB |
O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | ALA | A:166 | A:166 | 62.0 | 0.539 | G | -92.9 | -7.2 | 62.0 | 0.539 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | ALA | A:162 | A:166 | 27.0 | 0.235 | G | -90.1 | -4.5 | 27.0 | 0.235 | 0.0 |
HOH |
3.220 |
C |
O |
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| ALA | B:162 | B:166 | 31.0 | 0.27 | G | -84.1 | -3.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | ALA | A:167 | A:167 | 52.0 | 0.452 | G | -72.6 | -20.0 | |