Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 86245776 . G A CCDS6237.1:NM_001128829.2:c.428gCa>gTa_NP_001122301.1:p.143A>V Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5gmm 1 P00915 100.0 0.0 X-RAY
 2017-05-24 ALA A:143 A:142 0.0 0.0 E -128.3 125.0 0.0 0.0 0.0 ZN
949
HOH
 9.966
7.402
4.956
 O
O
N
 ZN
O20
O
ALA B:143 B:142 0.0 0.0 E -134.9 123.1 NA NA NA
6evr 1 P00915 100.0 0.0 X-RAY
 2018-06-06 ALA A:143 A:142 0.0 0.0 E -134.4 122.8 0.0 0.0 0.0 ZN
BZW
HOH
 9.979
7.210
4.862
 O
O
N
 ZN
O25
O
ALA B:143 B:142 0.0 0.0 E -134.6 123.1 NA NA NA
6ex1 1 P00915 100.0 0.0 X-RAY
 2018-10-10 ALA A:143 A:142 0.0 0.0 E -134.9 127.6 0.0 0.0 0.0 N19
HOH
 7.299
4.902
 O
N
 O25
O
ALA B:143 B:142 0.0 0.0 E -135.3 126.3 NA NA NA
6f3b 1 P00915 100.0 0.0 X-RAY
 2018-10-10 ALA A:143 A:142 0.0 0.0 E -133.4 125.6 0.0 0.0 0.0 ZN
CJK
HOH
 9.990
7.599
4.840
 O
O
N
 ZN
O21
O
ALA B:143 B:142 0.0 0.0 E -130.8 125.0 NA NA NA
6faf 1 P00915 100.0 0.0 X-RAY
 2018-10-10 ALA A:143 A:142 0.0 0.0 E -124.9 119.4 0.0 0.0 0.0 D3B
HOH
 7.183
5.055
 O
N
 C4
O
ALA B:143 B:142 0.0 0.0 E -127.3 117.5 NA NA NA
6fag 1 P00915 100.0 0.0 X-RAY
 2018-10-10 ALA A:143 A:142 0.0 0.0 E -126.0 124.8 0.0 0.0 0.0 EON
HOH
 7.121
4.678
 O
N
 C15
O
ALA B:143 B:142 0.0 0.0 E -131.2 118.8 NA NA NA
6g3v 1 P00915 100.0 0.0 X-RAY
 2018-11-28 ALA A:143 A:142 0.0 0.0 E -127.1 117.7 0.0 0.0 0.0 FO9
HOH
 7.465
4.673
 O
N
 O
O
ALA B:143 B:142 0.0 0.0 E -130.2 119.8 NA NA NA
6hwz 1 P00915 100.0 0.0 X-RAY
 2018-12-26 ALA A:143 A:143 0.0 0.0 E -126.0 122.6 0.0 0.0 0.0 GXE
HOH
 6.616
4.943
 O
N
 C2
O
ALA B:143 B:143 0.0 0.0 E -133.9 121.7 NA NA NA
6i0j 1 P00915 100.0 0.0 X-RAY
 2019-11-20 ALA A:143 A:142 0.0 0.0 E -128.3 125.0 0.0 0.0 0.0 GZE
HOH
 7.393
4.810
 O
N
 O3
O
ALA B:143 B:142 0.0 0.0 E -129.6 129.9 NA NA NA
6i0l 1 P00915 100.0 0.0 X-RAY
 2019-11-20 ALA A:143 A:142 0.0 0.0 E -131.2 122.9 0.0 0.0 0.0 GZH
HOH
 7.418
4.855
 O
N
 O13
O
ALA B:143 B:142 0.0 0.0 E -133.5 127.5 NA NA NA
6swm 1 P00915 100.0 0.0 X-RAY
 2020-10-07 ALA A:143 A:142 0.0 0.0 E -118.6 112.9 0.0 0.0 0.0 LVW
 6.324
 C
 O
ALA B:143 B:142 0.0 0.0 E -166.1 111.4 NA NA NA
6xze 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -135.7 123.6 0.0 0.0 0.0 O4Z
HOH
 7.222
4.883
 O
N
 O04
O
ALA B:143 B:142 0.0 0.0 E -136.9 125.1 NA NA NA
6xzo 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -135.0 123.9 0.0 0.0 0.0 O55
HOH
 7.239
4.907
 O
N
 O04
O
ALA B:143 B:142 0.0 0.0 E -135.5 126.9 NA NA NA
6xzs 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -135.4 123.2 0.0 0.0 0.0 O5K
HOH
 7.260
4.897
 O
N
 O04
O
ALA B:143 B:142 0.0 0.0 E -137.2 123.9 NA NA NA
6xzx 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -135.1 126.6 0.0 0.0 0.0 O5H
HOH
 6.933
4.944
 O
N
 C10
O
ALA B:143 B:142 0.0 0.0 E -135.3 127.1 NA NA NA
6xzy 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -134.0 124.4 0.0 0.0 0.0 O5N
HOH
 7.062
4.806
 O
N
 C10
O
ALA B:143 B:142 0.0 0.0 E -136.9 126.5 NA NA NA
6y00 1 P00915 100.0 0.0 X-RAY
 2020-09-23 ALA A:143 A:142 0.0 0.0 E -133.9 124.2 0.0 0.0 0.0 O5T
HOH
 7.262
4.874
 O
N
 N01
O
ALA B:143 B:142 0.0 0.0 E -135.3 124.1 NA NA NA
7q0d 1 P00915 100.0 0.0 X-RAY
 2022-01-12 ALA A:143 A:142 0.0 0.0 E -137.4 131.5 0.0 0.0 0.0 ZN
84Z
HOH
 9.911
6.177
4.928
 O
C
N
 ZN
CL1
O
ALA B:143 B:142 0.0 0.0 E -134.6 130.2 NA NA NA
1azm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -124.8 123.2 0.0 0.0 0.0 AZM
HOH
 7.474
4.871
 O
N
 O1
O
1bzm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -134.1 122.0 0.0 0.0 0.0 MZM
HOH
 7.485
4.984
 O
N
 O1
O
1czm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -135.0 125.6 0.0 0.0 0.0 AAS
HOH
 7.343
4.804
 O
N
 O1
O
1hcb 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -127.5 123.2 0.0 0.0 0.0 BCT
HOH
 8.024
5.084
 O
N
 O3
O
1hug 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -125.7 126.7 0.0 0.0 0.0 AUC
AUC
HOH
 6.846
8.212
5.010
 O
O
N
 C1
AU
O
1huh 1 P00915 100.0 0.0 X-RAY
 1994-04-30 ALA A:142 A:142 0.0 0.0 E -153.4 129.5 0.0 0.0 0.0 IOD
HOH
 8.981
5.037
 C
N
 I
O
2foy 1 P00915 100.0 0.0 X-RAY
 2006-04-04 ALA A:142 A:142 0.0 0.0 E -139.0 123.2 0.0 0.0 0.0 B30
HOH
 7.642
4.978
 O
N
 O2
O
ALA B:142 B:142 0.0 0.0 E -139.8 122.6 NA NA NA
2fw4 1 P00915 100.0 0.0 X-RAY
 2006-08-08 ALA A:142 A:142 0.0 0.0 E -123.4 132.5 0.0 0.0 0.0 ZN
HIS
HOH
 9.938
8.782
5.061
 O
O
N
 ZN
OXT
O
ALA B:142 B:142 0.0 0.0 E -137.4 125.2 NA NA NA
2nmx 1 P00915 100.0 0.0 X-RAY
 2007-04-24 ALA A:142 A:142 0.0 0.0 E -139.4 124.3 0.0 0.0 0.0 M25
HOH
 7.371
4.926
 O
N
 O1
O
ALA B:142 B:142 0.0 0.0 E -143.2 122.2 NA NA NA
2nn1 1 P00915 100.0 0.0 X-RAY
 2007-04-24 ALA A:142 A:142 0.0 0.0 E -136.7 122.6 0.0 0.0 0.0 M28
HOH
 7.301
4.836
 O
N
 C2
O
ALA B:142 B:142 0.0 0.0 E -140.6 121.3 NA NA NA
2nn7 1 P00915 100.0 0.0 X-RAY
 2007-05-08 ALA A:142 A:142 0.0 0.0 E -138.6 120.9 0.0 0.0 0.0 ZN
M29
HOH
 9.996
7.225
4.793
 O
O
N
 ZN
C2
O
ALA B:142 B:142 0.0 0.0 E -141.9 121.9 NA NA NA
3lxe 1 P00915 100.0 0.0 X-RAY
 2010-07-21 ALA A:142 A:142 0.0 0.0 E -132.5 123.6 0.0 0.0 0.0 TOR
HOH
 7.549
4.869
 O
N
 OAI
O
ALA B:142 B:142 0.0 0.0 E -137.7 118.5 NA NA NA
3w6h 1 P00915 100.0 0.0 X-RAY
 2013-03-13 ALA A:142 A:142 0.0 0.0 E -138.5 117.7 0.0 0.0 0.0 FLB
AZM
 9.248
7.536
 N
C
 F2
O1
ALA B:142 B:142 0.0 0.0 E -139.0 118.2 NA NA NA
3w6i 1 P00915 100.0 0.0 X-RAY
 2013-03-13 ALA A:142 A:142 0.0 0.0 E -128.5 120.5 0.0 0.0 0.0 FLB
HOH
 7.266
4.831
 O
N
 F2
O
ALA B:142 E:142 0.0 0.0 E -128.4 120.2 NA NA NA
4wr7 1 P00915 100.0 0.0 X-RAY
 2015-07-01 ALA A:142 A:142 0.0 0.0 E -130.6 125.1 0.0 0.0 0.0 3TV
HOH
 7.016
4.905
 O
N
 F16
O
ALA B:142 B:142 0.0 0.0 E -133.4 128.5 NA NA NA
4wup 1 P00915 100.0 0.0 X-RAY
 2015-07-01 ALA A:142 A:142 0.0 0.0 E -132.7 125.5 0.0 0.0 0.0 3UF
HOH
 7.258
4.933
 O
N
 O1
O
ALA B:142 B:142 0.0 0.0 E -136.9 126.9 NA NA NA
4wuq 1 P00915 100.0 0.0 X-RAY
 2015-07-01 ALA A:142 A:142 0.0 0.0 E -130.7 125.2 0.0 0.0 0.0 ZN
3UG
HOH
 9.996
6.735
4.864
 O
O
N
 ZN
F13
O
ALA B:142 B:142 0.0 0.0 E -135.5 125.3 NA NA NA
5e2m 1 P00915 100.0 0.0 X-RAY
 2016-10-05 ALA A:142 A:142 0.0 0.0 E -131.3 126.5 0.0 0.0 0.0 ZN
V14
HOH
 9.988
7.420
4.835
 O
O
N
 ZN
O9
O
ALA B:142 B:142 0.0 0.0 E -134.1 124.0 NA NA NA
1j9w 1 P00915 99.62 0.0 X-RAY
 2001-06-13 ALA A:142 A:142 0.0 0.0 E -130.7 126.6 0.0 0.0 0.0 ZN
EDO
HOH
 9.990
7.688
8.012
 O
O
CB
 ZN
O2
O
ALA B:142 B:142 0.0 0.0 E -141.3 120.7 NA NA NA
1jv0 1 P00915 99.62 0.0 X-RAY
 2001-09-19 ALA A:142 A:142 0.0 0.0 E -120.6 125.8 0.0 0.0 0.0 EDO
HOH
 7.585
4.888
 O
N
 O1
O
ALA B:142 B:142 0.0 0.0 E -145.1 127.0 NA NA NA
1crm 1 P00915 99.23 0.0 X-RAY
 1995-02-07 ALA A:142 A:142 0.0 0.0 E -127.5 126.3 0.0 0.0 0.0 HG
CL
HOH
 9.997
8.969
4.863
 O
C
N
 HG
CL
O
2cab 1 P00915 99.23 0.0 X-RAY
 1984-02-02 ALA A:142 A:142 0.0 0.0 E -129.4 123.1 0.0 0.0 0.0
2it4 1 P00915 100.0 0.0 X-RAY
 2007-09-11 ALA A:138 A:142 0.0 0.0 E -137.6 126.0 0.0 0.0 0.0 PPF
HOH
 6.792
4.754
 O
N
 O5
O
ALA B:138 B:142 0.0 0.0 E -131.5 122.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00915-f1 1 P00915 100.0 0.0 ALA A:143 A:143 0.0 0.0 E -128.9 128.4