Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr8 86245843 . C A CCDS6237.1:NM_001128829.2:c.361Gta>Tta_NP_001122301.1:p.121V>L Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5gmm 1 P00915 100.0 0.0 X-RAY
 2017-05-24 VAL A:121 A:120 0.0 0.0 E -117.8 113.0 0.0 0.0 0.0 ZN
949
949
HOH
 6.854
6.082
9.523
9.218
 N
N
C
CG1
 ZN
O20
O21
O
VAL B:121 B:120 1.0 0.006 E -115.1 114.4 NA NA NA
6evr 1 P00915 100.0 0.0 X-RAY
 2018-06-06 VAL A:121 A:120 0.0 0.0 E -116.6 114.9 0.0 0.0 0.0 ZN
BZW
HOH
 6.879
6.085
9.234
 N
N
CG2
 ZN
O25
O
VAL B:121 B:120 0.0 0.0 E -115.3 113.5 NA NA NA
6ex1 1 P00915 100.0 0.0 X-RAY
 2018-10-10 VAL A:121 A:120 1.0 0.006 E -115.9 112.9 1.0 0.006 0.0 ZN
N19
HOH
 6.888
6.113
9.267
 N
N
CG2
 ZN
O25
O
VAL B:121 B:120 0.0 0.0 E -111.7 111.6 NA NA NA
6f3b 1 P00915 100.0 0.0 X-RAY
 2018-10-10 VAL A:121 A:120 0.0 0.0 E -113.4 113.1 0.0 0.0 0.0 ZN
CJK
HOH
 6.934
6.564
9.148
 N
N
C
 ZN
O21
O
VAL B:121 B:120 0.0 0.0 E -114.9 111.9 NA NA NA
6faf 1 P00915 100.0 0.0 X-RAY
 2018-10-10 VAL A:121 A:120 0.0 0.0 E -112.7 109.5 0.0 0.0 0.0 ZN
D3B
HOH
 6.949
6.394
9.512
 N
N
CG1
 ZN
O3
O
VAL B:121 B:120 0.0 0.0 E -112.0 114.4 NA NA NA
6fag 1 P00915 100.0 0.0 X-RAY
 2018-10-10 VAL A:121 A:120 0.0 0.0 E -116.9 111.2 0.0 0.0 0.0 ZN
EON
HOH
 6.897
6.303
9.188
 N
N
CG1
 ZN
O20
O
VAL B:121 B:120 0.0 0.0 E -112.1 110.5 NA NA NA
6g3v 1 P00915 100.0 0.0 X-RAY
 2018-11-28 VAL A:121 A:120 0.0 0.0 E -115.4 114.3 0.0 0.0 0.0 ZN
FO9
HOH
 6.936
6.198
9.279
 N
N
CG1
 ZN
O
O
VAL B:121 B:120 0.0 0.0 E -117.0 110.9 NA NA NA
6hwz 1 P00915 100.0 0.0 X-RAY
 2018-12-26 VAL A:121 A:121 0.0 0.0 E -111.6 108.7 0.0 0.0 0.0 ZN
GXE
HOH
 7.042
6.416
9.331
 N
C
CG1
 ZN
C2
O
VAL B:121 B:121 0.0 0.0 E -110.5 111.1 NA NA NA
6i0j 1 P00915 100.0 0.0 X-RAY
 2019-11-20 VAL A:121 A:120 0.0 0.0 E -109.9 112.0 0.0 0.0 0.0 ZN
GZE
HOH
 6.983
6.341
9.145
 N
N
CG2
 ZN
O3
O
VAL B:121 B:120 1.0 0.006 E -115.7 113.3 NA NA NA
6i0l 1 P00915 100.0 0.0 X-RAY
 2019-11-20 VAL A:121 A:120 0.0 0.0 E -114.8 112.6 0.0 0.0 0.0 ZN
GZH
HOH
 6.932
6.141
9.290
 N
N
CG1
 ZN
O13
O
VAL B:121 B:120 1.0 0.006 E -117.2 112.9 NA NA NA
6swm 1 P00915 100.0 0.0 X-RAY
 2020-10-07 VAL A:121 A:120 0.0 0.0 E -109.9 107.0 0.0 0.0 0.0 ZN
LVW
 7.094
6.326
 N
C
 ZN
O
VAL B:121 B:120 0.0 0.0 E -109.0 117.8 NA NA NA
6xze 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -116.9 113.4 0.0 0.0 0.0 ZN
O4Z
HOH
 6.915
5.941
9.172
 N
N
CG2
 ZN
O04
O
VAL B:121 B:120 0.0 0.0 E -116.6 113.0 NA NA NA
6xzo 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -113.4 113.5 0.0 0.0 0.0 ZN
O55
HOH
 6.927
5.977
9.008
 N
N
C
 ZN
O04
O
VAL B:121 B:120 0.0 0.0 E -113.6 113.4 NA NA NA
6xzs 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -117.5 114.0 0.0 0.0 0.0 ZN
O5K
HOH
 6.905
5.912
9.162
 N
N
CG2
 ZN
O04
O
VAL B:121 B:120 0.0 0.0 E -115.9 113.8 NA NA NA
6xzx 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -115.7 112.7 0.0 0.0 0.0 ZN
O5H
HOH
 6.919
6.055
9.180
 N
N
CG2
 ZN
O04
O
VAL B:121 B:120 0.0 0.0 E -118.0 113.9 NA NA NA
6xzy 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -114.0 113.7 0.0 0.0 0.0 ZN
O5N
HOH
 6.925
6.011
9.244
 N
N
CG2
 ZN
O04
O
VAL B:121 B:120 0.0 0.0 E -116.2 114.7 NA NA NA
6y00 1 P00915 100.0 0.0 X-RAY
 2020-09-23 VAL A:121 A:120 0.0 0.0 E -115.8 113.3 0.0 0.0 0.0 ZN
O5T
HOH
 6.923
5.841
9.252
 N
N
CG2
 ZN
N01
O
VAL B:121 B:120 0.0 0.0 E -115.6 113.2 NA NA NA
7q0d 1 P00915 100.0 0.0 X-RAY
 2022-01-12 VAL A:121 A:120 0.0 0.0 E -113.2 111.0 0.0 0.0 0.0 ZN
84Z
HOH
 6.910
6.178
9.413
 N
N
CG1
 ZN
O8
O
VAL B:121 B:120 0.0 0.0 E -114.9 112.7 NA NA NA
1azm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 1.0 0.006 E -116.0 111.3 1.0 0.006 0.0 ZN
AZM
HOH
 6.850
6.418
9.343
 N
N
CG1
 ZN
O1
O
1bzm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 1.0 0.006 E -115.7 111.3 1.0 0.006 0.0 ZN
MZM
HOH
 6.892
6.333
9.220
 N
N
C
 ZN
O1
O
1czm 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 0.0 0.0 E -123.5 103.6 0.0 0.0 0.0 ZN
HG
AAS
HOH
 6.869
8.987
6.021
7.766
 N
CG2
N
CG2
 ZN
HG
O1
O
1hcb 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 0.0 0.0 E -116.4 110.4 0.0 0.0 0.0 ZN
BCT
HOH
 6.900
6.883
5.574
 N
N
N
 ZN
O3
O
1hug 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 1.0 0.006 E -116.2 110.9 1.0 0.006 0.0 ZN
AUC
AUC
HOH
 6.917
6.040
8.469
8.114
 N
N
C
O
 ZN
N1
AU
O
1huh 1 P00915 100.0 0.0 X-RAY
 1994-04-30 VAL A:120 A:120 1.0 0.006 E -118.4 110.1 1.0 0.006 0.0 ZN
IOD
IOD
HOH
 6.913
7.825
8.850
6.493
 N
N
CG2
C
 ZN
I
I
O
2foy 1 P00915 100.0 0.0 X-RAY
 2006-04-04 VAL A:120 A:120 1.0 0.006 E -118.6 110.8 1.0 0.006 0.0 ZN
B30
HOH
 6.913
6.315
8.976
 N
N
N
 ZN
O2
O
VAL B:120 B:120 2.0 0.013 E -117.6 111.7 NA NA NA
2fw4 1 P00915 100.0 0.0 X-RAY
 2006-08-08 VAL A:120 A:120 0.0 0.0 E -111.7 111.7 0.0 0.0 0.0 ZN
HIS
HOH
 6.927
8.883
6.707
 N
C
C
 ZN
N
O
VAL B:120 B:120 0.0 0.0 E -108.2 118.5 NA NA NA
2nmx 1 P00915 100.0 0.0 X-RAY
 2007-04-24 VAL A:120 A:120 0.0 0.0 E -114.2 108.7 0.0 0.0 0.0 ZN
M25
HOH
 6.855
6.097
9.109
 N
N
CG2
 ZN
O1
O
VAL B:120 B:120 0.0 0.0 E -115.2 107.8 NA NA NA
2nn1 1 P00915 100.0 0.0 X-RAY
 2007-04-24 VAL A:120 A:120 0.0 0.0 E -115.7 112.3 0.0 0.0 0.0 ZN
M28
HOH
 6.931
6.158
9.234
 N
N
CG2
 ZN
O1
O
VAL B:120 B:120 0.0 0.0 E -117.4 108.5 NA NA NA
2nn7 1 P00915 100.0 0.0 X-RAY
 2007-05-08 VAL A:120 A:120 1.0 0.006 E -114.8 111.8 1.0 0.006 0.0 ZN
M29
HOH
 6.901
6.123
9.128
 N
N
CG2
 ZN
O1
O
VAL B:120 B:120 1.0 0.006 E -118.1 108.5 NA NA NA
3lxe 1 P00915 100.0 0.0 X-RAY
 2010-07-21 VAL A:120 A:120 0.0 0.0 E -115.2 109.0 0.0 0.0 0.0 ZN
TOR
HOH
 6.948
6.217
9.297
 N
N
CG1
 ZN
OAI
O
VAL B:120 B:120 0.0 0.0 E -113.7 110.9 NA NA NA
3w6h 1 P00915 100.0 0.0 X-RAY
 2013-03-13 VAL A:120 A:120 1.0 0.006 E -121.4 109.3 1.0 0.006 0.0 ZN
AZM
 6.851
6.429
 N
N
 ZN
O2
VAL B:120 B:120 1.0 0.006 E -118.3 112.0 NA NA NA
3w6i 1 P00915 100.0 0.0 X-RAY
 2013-03-13 VAL A:120 A:120 1.0 0.006 E -107.8 113.5 1.0 0.006 0.0 FLB
ZN
HOH
 6.849
7.100
8.080
 C
N
N
 F1
ZN
O
VAL B:120 E:120 0.0 0.0 E -107.7 113.2 NA NA NA
4wr7 1 P00915 100.0 0.0 X-RAY
 2015-07-01 VAL A:120 A:120 0.0 0.0 E -117.8 113.3 0.0 0.0 0.0 ZN
3TV
HOH
 6.860
6.094
9.018
 N
N
N
 ZN
O3
O
VAL B:120 B:120 0.0 0.0 E -122.9 112.4 NA NA NA
4wup 1 P00915 100.0 0.0 X-RAY
 2015-07-01 VAL A:120 A:120 0.0 0.0 E -120.0 109.9 0.0 0.0 0.0 ZN
3UF
HOH
 6.890
6.021
9.144
 N
N
CG2
 ZN
O1
O
VAL B:120 B:120 1.0 0.006 E -115.8 112.9 NA NA NA
4wuq 1 P00915 100.0 0.0 X-RAY
 2015-07-01 VAL A:120 A:120 0.0 0.0 E -118.5 115.1 0.0 0.0 0.0 ZN
3UG
HOH
 6.896
6.068
9.023
 N
N
CG2
 ZN
O3
O
VAL B:120 B:120 0.0 0.0 E -117.4 112.2 NA NA NA
5e2m 1 P00915 100.0 0.0 X-RAY
 2016-10-05 VAL A:120 A:120 0.0 0.0 E -116.9 113.7 0.0 0.0 0.0 ZN
V14
HOH
 6.895
6.343
9.099
 N
N
CG2
 ZN
O9
O
VAL B:120 B:120 0.0 0.0 E -118.3 112.4 NA NA NA
1j9w 1 P00915 99.62 0.0 X-RAY
 2001-06-13 VAL A:120 A:120 0.0 0.0 E -111.0 117.2 0.0 0.0 0.0 ZN
EDO
HOH
 6.841
6.778
9.150
 N
N
CG2
 ZN
O2
O
VAL B:120 B:120 1.0 0.006 E -125.7 114.7 NA NA NA
1jv0 1 P00915 99.62 0.0 X-RAY
 2001-09-19 VAL A:120 A:120 1.0 0.006 E -119.8 111.6 1.0 0.006 0.0 ZN
CL
EDO
HOH
 6.856
9.832
7.373
8.386
 N
N
N
C
 ZN
CL
O1
O
VAL B:120 B:120 0.0 0.0 E -118.3 108.8 NA NA NA
1crm 1 P00915 99.23 0.0 X-RAY
 1995-02-07 VAL A:120 A:120 1.0 0.006 E -113.0 111.2 1.0 0.006 0.0 HG
HG
CL
HOH
 7.196
9.027
7.953
8.960
 N
CG2
N
C
 HG
HG
CL
O
2cab 1 P00915 99.23 0.0 X-RAY
 1984-02-02 VAL A:120 A:120 0.0 0.0 E -113.1 112.2 0.0 0.0 0.0 ZN
 6.818
 N
 ZN
2it4 1 P00915 100.0 0.0 X-RAY
 2007-09-11 VAL A:116 A:120 0.0 0.0 E -112.2 111.6 0.0 0.0 0.0 ZN
PPF
HOH
 6.890
6.135
8.390
 N
C
C
 ZN
O4
O
VAL B:116 B:120 1.0 0.006 E -118.4 114.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00915-f1 1 P00915 100.0 0.0 VAL A:121 A:121 0.0 0.0 E -102.2 108.2