Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86249176 | . | C | A | CCDS6237.1:NM_001128829.2:c.352Gag>Tag_NP_001122301.1:p.118E>* | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -152.5 | 133.4 | 0.0 | 0.0 | 0.0 |
ZN 949 HOH |
6.338 7.532 6.646 |
O OE2 O |
ZN O20 O |
||
| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -147.9 | 140.2 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -148.5 | 138.5 | 0.0 | 0.0 | 0.0 |
ZN BZW ACT HOH |
6.349 7.463 7.351 6.688 |
O OE2 OE1 O |
ZN N27 O O |
||
| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -147.6 | 133.9 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -149.9 | 135.4 | 0.0 | 0.0 | 0.0 |
ZN N19 ACT HOH |
6.383 7.537 7.766 6.741 |
O OE2 OE1 O |
ZN O25 O O |
||
| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -144.6 | 135.9 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -152.1 | 134.9 | 0.0 | 0.0 | 0.0 |
ZN CJK ACT HOH |
6.395 7.643 7.379 6.676 |
O OE2 OE1 O |
ZN N23 CH3 O |
||
| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -149.5 | 135.8 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -147.6 | 128.4 | 0.0 | 0.0 | 0.0 |
ZN D3B HOH |
6.224 7.062 6.403 |
O OE2 OE1 |
ZN O3 O |
||
| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -148.2 | 132.3 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -142.0 | 128.4 | 0.0 | 0.0 | 0.0 |
ZN EON HOH |
6.274 7.192 6.672 |
O OE2 OE1 |
ZN O20 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -144.1 | 136.4 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -150.2 | 136.6 | 0.0 | 0.0 | 0.0 |
ZN FO9 HOH |
6.382 7.645 6.721 |
O OE1 O |
ZN O O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -147.1 | 139.8 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | GLU | A:118 | A:118 | 0.0 | 0.0 | E | -143.6 | 133.3 | 0.0 | 0.0 | 0.0 |
ZN GXE HOH |
6.493 7.873 6.628 |
O OE1 O |
ZN SE O |
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| GLU | B:118 | B:118 | 0.0 | 0.0 | E | -147.9 | 132.0 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -149.2 | 135.8 | 0.0 | 0.0 | 0.0 |
ZN ACT GZE HOH |
6.363 7.617 7.413 6.679 |
O OE1 OE2 O |
ZN O O5 O |
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| GLU | B:118 | B:117 | 1.0 | 0.005 | E | -149.9 | 138.7 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -149.7 | 131.8 | 0.0 | 0.0 | 0.0 |
ZN GZH ACT HOH |
6.366 7.417 7.457 6.691 |
O OE2 OE1 O |
ZN O13 CH3 O |
||
| GLU | B:118 | B:117 | 1.0 | 0.005 | E | -149.7 | 136.2 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -143.7 | 134.8 | 0.0 | 0.0 | 0.0 |
ZN LVW HOH |
6.363 7.964 7.178 |
O OE1 CG |
ZN SE O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -149.1 | 137.8 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -154.4 | 134.2 | 0.0 | 0.0 | 0.0 |
ZN O4Z HOH |
6.356 7.578 6.718 |
O OE1 O |
ZN N01 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -152.0 | 136.1 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -151.6 | 134.4 | 0.0 | 0.0 | 0.0 |
ZN O55 HOH |
6.313 7.534 6.694 |
O OE1 O |
ZN O04 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -148.5 | 138.2 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -154.0 | 133.7 | 0.0 | 0.0 | 0.0 |
ZN O5K HOH |
6.327 7.537 6.682 |
O OE1 O |
ZN N01 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -152.2 | 135.8 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -151.6 | 134.6 | 0.0 | 0.0 | 0.0 |
ZN O5H HOH |
6.288 7.037 6.714 |
O OE1 O |
ZN O04 O |
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| GLU | B:118 | B:117 | 1.0 | 0.005 | E | -151.9 | 135.8 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -153.0 | 136.6 | 0.0 | 0.0 | 0.0 |
ZN O5N HOH |
6.387 7.093 6.732 |
O OE1 OE2 |
ZN O04 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -152.3 | 136.0 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -152.1 | 135.0 | 0.0 | 0.0 | 0.0 |
ZN O5T HOH |
6.336 7.484 6.647 |
O OE1 O |
ZN N01 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -150.5 | 136.4 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | GLU | A:118 | A:117 | 0.0 | 0.0 | E | -149.8 | 137.1 | 0.0 | 0.0 | 0.0 |
ZN 84Z EDO ACT HOH |
6.380 7.513 9.248 9.015 6.662 |
O OE1 OE2 OE2 O |
ZN O8 O1 CH3 O |
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| GLU | B:118 | B:117 | 0.0 | 0.0 | E | -149.2 | 136.3 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 1.0 | 0.005 | E | -152.4 | 135.5 | 1.0 | 0.005 | 0.0 |
ZN AZM HOH |
6.392 7.528 6.873 |
O OE2 O |
ZN N1 O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 1.0 | 0.005 | E | -153.3 | 135.2 | 1.0 | 0.005 | 0.0 |
ZN MZM HOH |
6.361 7.337 6.673 |
O OE2 O |
ZN N1 O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 1.0 | 0.005 | E | -149.9 | 136.6 | 1.0 | 0.005 | 0.0 |
ZN HG AAS HOH |
6.508 7.125 7.414 6.780 |
OE2 CG OE2 O |
ZN HG N1 O |
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| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -150.8 | 135.4 | 0.0 | 0.0 | 0.0 |
ZN BCT HOH |
6.423 7.435 6.749 |
O OE2 O |
ZN O1 O |
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| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -151.1 | 134.0 | 0.0 | 0.0 | 0.0 |
ZN AUC HOH |
6.201 8.057 6.677 |
O OE2 O |
ZN N1 O |
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| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -143.2 | 129.0 | 0.0 | 0.0 | 0.0 |
ZN IOD HOH |
6.157 7.644 6.372 |
O OE2 O |
ZN I O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -148.5 | 137.5 | 0.0 | 0.0 | 0.0 |
ZN B30 HOH |
6.385 7.885 6.759 |
O OE2 O |
ZN N1 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -150.3 | 137.5 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -147.5 | 134.8 | 0.0 | 0.0 | 0.0 |
ZN HOH |
6.511 6.703 |
O O |
ZN O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -148.5 | 135.6 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -148.4 | 136.9 | 0.0 | 0.0 | 0.0 |
ZN M25 HOH |
6.196 7.306 6.717 |
O OE2 O |
ZN O1 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -149.4 | 139.3 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -147.1 | 139.2 | 0.0 | 0.0 | 0.0 |
ZN M28 HOH |
6.408 7.204 6.700 |
O OE2 O |
ZN O1 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -151.5 | 139.7 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -150.7 | 138.4 | 0.0 | 0.0 | 0.0 |
ZN M29 HOH |
6.341 7.153 6.741 |
O OE2 O |
ZN O1 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -150.6 | 140.6 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -153.7 | 133.5 | 0.0 | 0.0 | 0.0 |
ZN TOR HOH |
6.198 7.598 6.632 |
O OE1 OE2 |
ZN NAP O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -152.8 | 136.4 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -152.2 | 137.5 | 0.0 | 0.0 | 0.0 |
ZN AZM |
6.272 7.511 |
O OE2 |
ZN N1 |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -154.0 | 137.9 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -150.8 | 132.9 | 0.0 | 0.0 | 0.0 |
ZN HOH |
6.619 6.615 |
O O |
ZN O |
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| GLU | B:117 | E:117 | 0.0 | 0.0 | E | -151.1 | 132.7 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -152.3 | 135.2 | 0.0 | 0.0 | 0.0 |
ZN 3TV HOH |
6.368 7.670 6.686 |
O OE1 O |
ZN O3 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -148.6 | 136.9 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -152.6 | 136.7 | 0.0 | 0.0 | 0.0 |
ZN 3UF HOH |
6.316 7.382 6.660 |
O OE1 O |
ZN N3 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -150.7 | 136.4 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -146.6 | 136.1 | 0.0 | 0.0 | 0.0 |
ZN 3UG HOH |
6.378 7.591 6.646 |
O OE1 O |
ZN O3 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -147.5 | 136.3 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -146.6 | 137.7 | 0.0 | 0.0 | 0.0 |
ZN V14 HOH |
6.314 7.320 6.629 |
O OE1 O |
ZN N10 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -149.0 | 136.7 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -147.4 | 138.1 | 0.0 | 0.0 | 0.0 |
ZN EDO HOH |
6.244 7.879 6.453 |
O OE2 O |
ZN O1 O |
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| GLU | B:117 | B:117 | 1.0 | 0.005 | E | -144.5 | 147.0 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | GLU | A:117 | A:117 | 1.0 | 0.005 | E | -152.7 | 127.5 | 1.0 | 0.005 | 0.0 |
ZN CL EDO HOH |
6.311 9.105 7.535 6.641 |
O O OE2 O |
ZN CL O2 O |
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| GLU | B:117 | B:117 | 0.0 | 0.0 | E | -152.2 | 139.2 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | GLU | A:117 | A:117 | 1.0 | 0.005 | E | -154.2 | 136.0 | 1.0 | 0.005 | 0.0 |
HG CL HOH |
6.753 7.992 6.828 |
OE2 OE2 O |
HG CL O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | GLU | A:117 | A:117 | 0.0 | 0.0 | E | -141.4 | 132.9 | 0.0 | 0.0 | 0.0 |
ZN |
6.289 |
O |
ZN |
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| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | GLU | A:113 | A:117 | 0.0 | 0.0 | E | -145.7 | 139.4 | 0.0 | 0.0 | 0.0 |
ZN PPF HOH |
6.413 7.909 6.509 |
O OE2 O |
ZN O3 O |
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| GLU | B:113 | B:117 | 0.0 | 0.0 | E | -147.5 | 134.8 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | GLU | A:118 | A:118 | 0.0 | 0.0 | E | -141.6 | 128.3 | |