Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86249226 | . | G | A | CCDS6237.1:NM_001128829.2:c.302aCa>aTa_NP_001122301.1:p.101T>I | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | THR | A:101 | A:100 | 63.0 | 0.45 | B | -112.2 | 162.3 | 63.0 | 0.45 | 0.0 |
HOH |
2.673 |
O |
O |
||
THR | B:101 | B:100 | 71.0 | 0.507 | S | -112.7 | 154.1 | NA | NA | NA | |||||||||||||
6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | THR | A:101 | A:100 | 75.0 | 0.536 | S | -138.7 | 173.1 | 75.0 | 0.536 | 0.0 |
ACT HOH |
7.510 3.030 |
O O |
O O |
||
THR | B:101 | B:100 | 69.0 | 0.493 | S | -124.2 | 170.7 | NA | NA | NA | |||||||||||||
6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | THR | A:101 | A:100 | 55.0 | 0.393 | S | -128.1 | 164.9 | 55.0 | 0.393 | 0.0 |
ACT HOH |
7.415 2.945 |
O O |
O O |
||
THR | B:101 | B:100 | 70.0 | 0.5 | S | -134.2 | 172.8 | NA | NA | NA | |||||||||||||
6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | THR | A:101 | A:100 | 72.0 | 0.514 | S | -136.5 | 172.1 | 72.0 | 0.514 | 0.0 |
ACT HOH |
7.597 2.919 |
O O |
CH3 O |
||
THR | B:101 | B:100 | 53.0 | 0.379 | S | -130.4 | 169.6 | NA | NA | NA | |||||||||||||
6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | THR | A:101 | A:100 | 66.0 | 0.471 | S | -129.1 | 170.2 | 66.0 | 0.471 | 0.0 |
GOL HOH |
5.254 2.911 |
N O |
O2 O |
||
THR | B:101 | B:100 | 66.0 | 0.471 | S | -115.0 | 174.4 | NA | NA | NA | |||||||||||||
6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | THR | A:101 | A:100 | 62.0 | 0.443 | S | -127.9 | 164.7 | 62.0 | 0.443 | 0.0 |
HOH |
2.982 |
O |
O |
||
THR | B:101 | B:100 | 68.0 | 0.486 | S | -122.0 | 172.5 | NA | NA | NA | |||||||||||||
6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | THR | A:101 | A:100 | 68.0 | 0.486 | S | -131.1 | 171.4 | 68.0 | 0.486 | 0.0 |
HOH |
3.071 |
O |
O |
||
THR | B:101 | B:100 | 70.0 | 0.5 | S | -114.5 | 173.3 | NA | NA | NA | |||||||||||||
6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | THR | A:101 | A:101 | 59.0 | 0.421 | S | -120.5 | 157.8 | 59.0 | 0.421 | 0.0 |
HOH |
2.971 |
O |
O |
||
THR | B:101 | B:101 | 66.0 | 0.471 | S | -127.7 | 166.8 | NA | NA | NA | |||||||||||||
6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | THR | A:101 | A:100 | 60.0 | 0.429 | S | -139.6 | 170.6 | 60.0 | 0.429 | 0.0 |
ACT HOH |
7.415 2.953 |
O O |
O O |
||
THR | B:101 | B:100 | 60.0 | 0.429 | S | -128.2 | 162.6 | NA | NA | NA | |||||||||||||
6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | THR | A:101 | A:100 | 62.0 | 0.443 | S | -135.1 | 167.8 | 62.0 | 0.443 | 0.0 |
ACT HOH |
7.439 3.003 |
O O |
CH3 O |
||
THR | B:101 | B:100 | 62.0 | 0.443 | S | -123.9 | 164.0 | NA | NA | NA | |||||||||||||
6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | THR | A:101 | A:100 | 70.0 | 0.5 | S | -126.3 | 167.7 | 70.0 | 0.5 | 0.0 | ||||||
THR | B:101 | B:100 | 79.0 | 0.564 | S | -121.2 | 163.2 | NA | NA | NA | |||||||||||||
6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 75.0 | 0.536 | S | -132.4 | 171.4 | 75.0 | 0.536 | 0.0 |
HOH |
2.873 |
O |
O |
||
THR | B:101 | B:100 | 68.0 | 0.486 | S | -123.1 | 172.2 | NA | NA | NA | |||||||||||||
6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 61.0 | 0.436 | S | -136.5 | 178.8 | 61.0 | 0.436 | 0.0 |
HOH |
2.861 |
O |
O |
||
THR | B:101 | B:100 | 64.0 | 0.457 | S | -126.7 | 166.0 | NA | NA | NA | |||||||||||||
6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 68.0 | 0.486 | S | -137.9 | 177.5 | 68.0 | 0.486 | 0.0 |
HOH |
2.737 |
O |
O |
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THR | B:101 | B:100 | 61.0 | 0.436 | S | -126.3 | 170.7 | NA | NA | NA | |||||||||||||
6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 69.0 | 0.493 | S | -131.9 | 174.8 | 69.0 | 0.493 | 0.0 |
HOH |
2.815 |
O |
O |
||
THR | B:101 | B:100 | 72.0 | 0.514 | S | -120.7 | 172.1 | NA | NA | NA | |||||||||||||
6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 68.0 | 0.486 | S | -136.2 | 177.3 | 68.0 | 0.486 | 0.0 |
HOH |
2.772 |
O |
O |
||
THR | B:101 | B:100 | 69.0 | 0.493 | S | -123.8 | 171.1 | NA | NA | NA | |||||||||||||
6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | THR | A:101 | A:100 | 70.0 | 0.5 | S | -136.8 | 177.0 | 70.0 | 0.5 | 0.0 |
HOH |
2.823 |
O |
O |
||
THR | B:101 | B:100 | 65.0 | 0.464 | S | -127.6 | 170.1 | NA | NA | NA | |||||||||||||
7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | THR | A:101 | A:100 | 65.0 | 0.464 | S | -119.8 | 159.8 | 65.0 | 0.464 | 0.0 |
HOH |
2.734 |
O |
O |
||
THR | B:101 | B:100 | 63.0 | 0.45 | B | -148.9 | 172.6 | NA | NA | NA | |||||||||||||
1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 62.0 | 0.443 | S | -115.7 | 150.3 | 62.0 | 0.443 | 0.0 |
HOH |
2.785 |
O |
O |
||
1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 72.0 | 0.514 | S | -114.8 | 153.3 | 72.0 | 0.514 | 0.0 |
HOH |
2.776 |
O |
O |
||
1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 62.0 | 0.443 | S | -111.6 | 154.7 | 62.0 | 0.443 | 0.0 |
HOH |
2.588 |
OG1 |
O |
||
1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 61.0 | 0.436 | S | -110.1 | 161.1 | 61.0 | 0.436 | 0.0 |
HOH |
2.796 |
O |
O |
||
1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 60.0 | 0.429 | S | -115.4 | 151.5 | 60.0 | 0.429 | 0.0 |
HOH |
2.529 |
OG1 |
O |
||
1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | THR | A:100 | A:100 | 59.0 | 0.421 | S | -118.4 | 149.9 | 59.0 | 0.421 | 0.0 |
IOD HOH |
9.924 2.707 |
OG1 OG1 |
I O |
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2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | THR | A:100 | A:100 | 64.0 | 0.457 | S | -141.9 | 170.3 | 64.0 | 0.457 | 0.0 |
B30 B30 HOH |
6.907 4.877 2.950 |
N N O |
OXA O2 O |
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THR | B:100 | B:100 | 65.0 | 0.464 | S | -141.1 | 171.8 | NA | NA | NA | |||||||||||||
2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | THR | A:100 | A:100 | 69.0 | 0.493 | S | -123.1 | 155.8 | 69.0 | 0.493 | 0.0 |
HOH |
3.209 |
O |
O |
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THR | B:100 | B:100 | 68.0 | 0.486 | S | -117.0 | 155.0 | NA | NA | NA | |||||||||||||
2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | THR | A:100 | A:100 | 72.0 | 0.514 | S | -138.3 | 169.5 | 72.0 | 0.514 | 0.0 |
HOH |
2.848 |
O |
O |
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THR | B:100 | B:100 | 49.0 | 0.35 | S | -135.0 | 172.9 | NA | NA | NA | |||||||||||||
2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | THR | A:100 | A:100 | 66.0 | 0.471 | S | -139.7 | 171.2 | 66.0 | 0.471 | 0.0 |
HOH |
2.861 |
O |
O |
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THR | B:100 | B:100 | 53.0 | 0.379 | S | -128.2 | 174.8 | NA | NA | NA | |||||||||||||
2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | THR | A:100 | A:100 | 70.0 | 0.5 | S | -135.9 | 170.9 | 70.0 | 0.5 | 0.0 |
HOH |
2.980 |
O |
O |
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THR | B:100 | B:100 | 64.0 | 0.457 | S | -125.4 | 175.3 | NA | NA | NA | |||||||||||||
3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | THR | A:100 | A:100 | 68.0 | 0.486 | S | -137.7 | 168.9 | 68.0 | 0.486 | 0.0 |
HOH |
2.843 |
O |
O |
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THR | B:100 | B:100 | 58.0 | 0.414 | S | -130.0 | 177.5 | NA | NA | NA | |||||||||||||
3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | THR | A:100 | A:100 | 63.0 | 0.45 | S | -122.2 | -163.8 | 63.0 | 0.45 | 0.0 | ||||||
THR | B:100 | B:100 | 63.0 | 0.45 | S | -125.8 | -164.9 | NA | NA | NA | |||||||||||||
3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | THR | A:100 | A:100 | 68.0 | 0.486 | S | -133.1 | 159.6 | 68.0 | 0.486 | 0.0 |
HOH |
2.990 |
O |
O |
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THR | B:100 | E:100 | 67.0 | 0.479 | S | -133.4 | 159.2 | NA | NA | NA | |||||||||||||
4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | THR | A:100 | A:100 | 71.0 | 0.507 | S | -143.8 | 175.4 | 71.0 | 0.507 | 0.0 |
HOH |
2.944 |
O |
O |
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THR | B:100 | B:100 | 58.0 | 0.414 | B | -135.4 | 169.3 | NA | NA | NA | |||||||||||||
4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | THR | A:100 | A:100 | 66.0 | 0.471 | S | -131.4 | 171.0 | 66.0 | 0.471 | 0.0 |
HOH |
2.913 |
O |
O |
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THR | B:100 | B:100 | 58.0 | 0.414 | S | -118.3 | 170.4 | NA | NA | NA | |||||||||||||
4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | THR | A:100 | A:100 | 64.0 | 0.457 | S | -136.1 | 168.0 | 64.0 | 0.457 | 0.0 |
HOH |
3.002 |
O |
O |
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THR | B:100 | B:100 | 64.0 | 0.457 | S | -126.3 | 171.1 | NA | NA | NA | |||||||||||||
5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | THR | A:100 | A:100 | 61.0 | 0.436 | S | -138.2 | 172.9 | 61.0 | 0.436 | 0.0 |
HOH |
2.888 |
O |
O |
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THR | B:100 | B:100 | 59.0 | 0.421 | S | -136.4 | 174.0 | NA | NA | NA | |||||||||||||
1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | THR | A:100 | A:100 | 64.0 | 0.457 | S | -126.8 | 165.4 | 64.0 | 0.457 | 0.0 |
HOH |
2.979 |
O |
O |
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THR | B:100 | B:100 | 78.0 | 0.557 | S | -111.9 | 155.9 | NA | NA | NA | |||||||||||||
1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | THR | A:100 | A:100 | 75.0 | 0.536 | S | -123.9 | 175.8 | 75.0 | 0.536 | 0.0 |
ZN HOH |
9.422 2.917 |
N O |
ZN O |
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THR | B:100 | B:100 | 86.0 | 0.614 | S | -107.1 | 165.1 | NA | NA | NA | |||||||||||||
1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | THR | A:100 | A:100 | 62.0 | 0.443 | S | -114.4 | 153.7 | 62.0 | 0.443 | 0.0 |
HG HOH |
5.403 2.566 |
N OG1 |
HG O |
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2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | THR | A:100 | A:100 | 60.0 | 0.429 | S | -108.5 | 153.4 | 60.0 | 0.429 | 0.0 | ||||||
2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | THR | A:96 | A:100 | 70.0 | 0.5 | B | -134.6 | 162.1 | 70.0 | 0.5 | 0.0 |
HOH |
2.744 |
OG1 |
O |
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THR | B:96 | B:100 | 82.0 | 0.586 | S | -125.9 | 162.9 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | THR | A:101 | A:101 | 54.0 | 0.386 | S | -133.0 | 175.8 |