Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86249260 | . | T | A | CCDS6237.1:NM_001128829.2:c.268Agg>Tgg_NP_001122301.1:p.90R>W | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -93.0 | 127.7 | 33.0 | 0.147 | 0.0 |
949 949 HOH |
9.916 9.970 3.330 |
O O NH2 |
C23 O20 O |
||
| ARG | B:90 | B:89 | 37.0 | 0.164 | E | -86.7 | 126.0 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -96.2 | 129.1 | 33.0 | 0.147 | 0.0 |
HOH |
2.992 |
NH1 |
O |
||
| ARG | B:90 | B:89 | 35.0 | 0.156 | E | -95.3 | 126.8 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:90 | A:89 | 30.0 | 0.133 | E | -96.3 | 125.3 | 30.0 | 0.133 | 0.0 |
N19 HOH |
9.991 3.144 |
O NH1 |
O11 O |
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| ARG | B:90 | B:89 | 26.0 | 0.116 | E | -94.2 | 124.6 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:90 | A:89 | 30.0 | 0.133 | E | -96.5 | 128.0 | 30.0 | 0.133 | 0.0 |
HOH |
3.079 |
NH1 |
O |
||
| ARG | B:90 | B:89 | 26.0 | 0.116 | E | -95.7 | 124.7 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:90 | A:89 | 34.0 | 0.151 | E | -101.0 | 124.9 | 34.0 | 0.151 | 0.0 |
D3B HOH |
9.705 3.374 |
O N |
C3 O |
||
| ARG | B:90 | B:89 | 28.0 | 0.124 | E | -100.7 | 124.5 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -96.2 | 128.3 | 33.0 | 0.147 | 0.0 |
EON HOH |
9.724 4.030 |
O CG |
C16 O |
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| ARG | B:90 | B:89 | 31.0 | 0.138 | E | -96.6 | 124.5 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | ARG | A:90 | A:89 | 31.0 | 0.138 | E | -100.1 | 130.4 | 31.0 | 0.138 | 0.0 |
HOH |
4.031 |
CG |
O |
||
| ARG | B:90 | B:89 | 33.0 | 0.147 | E | -91.7 | 126.4 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | ARG | A:90 | A:90 | 31.0 | 0.138 | E | -101.1 | 127.5 | 31.0 | 0.138 | 0.0 |
HOH |
4.176 |
CG |
O |
||
| ARG | B:90 | B:90 | 32.0 | 0.142 | E | -99.1 | 127.6 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:90 | A:89 | 34.0 | 0.151 | E | -97.0 | 125.9 | 34.0 | 0.151 | 0.0 |
GZE HOH |
9.504 3.431 |
O N |
F12 O |
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| ARG | B:90 | B:89 | 32.0 | 0.142 | E | -89.3 | 124.1 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -97.6 | 125.3 | 33.0 | 0.147 | 0.0 |
HOH |
3.343 |
NH2 |
O |
||
| ARG | B:90 | B:89 | 27.0 | 0.12 | E | -95.2 | 124.9 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | ARG | A:90 | A:89 | 30.0 | 0.133 | E | -102.2 | 136.9 | 30.0 | 0.133 | 0.0 |
LVW HOH |
9.520 4.510 |
O NH2 |
C3 O |
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| ARG | B:90 | B:89 | 32.0 | 0.142 | E | -107.8 | 129.2 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 32.0 | 0.142 | E | -97.0 | 126.0 | 32.0 | 0.142 | 0.0 |
HOH |
2.802 |
NH1 |
O |
||
| ARG | B:90 | B:89 | 34.0 | 0.151 | E | -93.8 | 127.1 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -98.1 | 126.8 | 33.0 | 0.147 | 0.0 |
O55 HOH |
9.725 3.461 |
O N |
O13 O |
||
| ARG | B:90 | B:89 | 28.0 | 0.124 | E | -89.5 | 125.5 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 34.0 | 0.151 | E | -95.5 | 126.8 | 34.0 | 0.151 | 0.0 |
HOH |
3.523 |
N |
O |
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| ARG | B:90 | B:89 | 31.0 | 0.138 | E | -92.9 | 128.7 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 32.0 | 0.142 | E | -97.2 | 126.3 | 32.0 | 0.142 | 0.0 |
O5H HOH |
9.627 3.096 |
O NH1 |
C09 O |
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| ARG | B:90 | B:89 | 32.0 | 0.142 | E | -88.7 | 123.5 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 31.0 | 0.138 | E | -99.8 | 125.6 | 31.0 | 0.138 | 0.0 |
O5N HOH |
9.610 3.469 |
O N |
C09 O |
||
| ARG | B:90 | B:89 | 32.0 | 0.142 | E | -91.7 | 123.6 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ARG | A:90 | A:89 | 33.0 | 0.147 | E | -96.8 | 126.2 | 33.0 | 0.147 | 0.0 |
HOH |
3.565 |
N |
O |
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| ARG | B:90 | B:89 | 27.0 | 0.12 | E | -92.6 | 125.9 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ARG | A:90 | A:89 | 32.0 | 0.142 | E | -89.9 | 117.7 | 32.0 | 0.142 | 0.0 |
HOH |
2.619 |
NH2 |
O |
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| ARG | B:90 | B:89 | 33.0 | 0.147 | E | -93.0 | 130.7 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 38.0 | 0.169 | E | -81.5 | 122.6 | 38.0 | 0.169 | 0.0 |
AZM HOH |
9.481 3.881 |
O CG |
O3 O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 36.0 | 0.16 | E | -87.5 | 130.6 | 36.0 | 0.16 | 0.0 |
MZM HOH |
9.633 3.389 |
O NH2 |
O3 O |
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| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 33.0 | 0.147 | E | -89.7 | 125.3 | 33.0 | 0.147 | 0.0 |
HOH |
3.211 |
NH1 |
O |
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| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 38.0 | 0.169 | E | -94.7 | 121.2 | 38.0 | 0.169 | 0.0 |
HOH |
2.973 |
NH2 |
O |
||
| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 41.0 | 0.182 | E | -83.3 | 121.9 | 41.0 | 0.182 | 0.0 |
AUC AUC HOH |
9.434 9.872 4.070 |
O O CG |
C2 AU O |
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| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ARG | A:89 | A:89 | 39.0 | 0.173 | E | -93.1 | 127.3 | 39.0 | 0.173 | 0.0 |
IOD HOH |
6.759 3.192 |
NH2 NH2 |
I O |
||
| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | ARG | A:89 | A:89 | 30.0 | 0.133 | E | -95.8 | 126.6 | 30.0 | 0.133 | 0.0 |
HOH |
3.971 |
CG |
O |
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| ARG | B:89 | B:89 | 27.0 | 0.12 | E | -87.7 | 125.1 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | ARG | A:89 | A:89 | 33.0 | 0.147 | E | -107.5 | 120.4 | 33.0 | 0.147 | 0.0 |
HIS HOH |
9.955 3.510 |
O N |
CD2 O |
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| ARG | B:89 | B:89 | 34.0 | 0.151 | E | -89.2 | 128.5 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ARG | A:89 | A:89 | 31.0 | 0.138 | E | -93.6 | 127.5 | 31.0 | 0.138 | 0.0 |
HOH |
3.275 |
N |
O |
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| ARG | B:89 | B:89 | 25.0 | 0.111 | E | -91.2 | 125.5 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ARG | A:89 | A:89 | 32.0 | 0.142 | E | -93.0 | 126.2 | 32.0 | 0.142 | 0.0 |
HOH |
3.414 |
N |
O |
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| ARG | B:89 | B:89 | 24.0 | 0.107 | E | -89.4 | 126.8 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | ARG | A:89 | A:89 | 30.0 | 0.133 | E | -93.7 | 126.3 | 30.0 | 0.133 | 0.0 |
HOH |
3.305 |
N |
O |
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| ARG | B:89 | B:89 | 33.0 | 0.147 | E | -90.2 | 127.3 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | ARG | A:89 | A:89 | 30.0 | 0.133 | E | -89.9 | 126.5 | 30.0 | 0.133 | 0.0 |
TOR HOH |
9.726 3.342 |
O N |
CAV O |
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| ARG | B:89 | B:89 | 28.0 | 0.124 | E | -87.0 | 124.8 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ARG | A:89 | A:89 | 26.0 | 0.116 | E | -102.9 | 124.1 | 26.0 | 0.116 | 0.0 |
FLB |
9.804 |
O |
O2 |
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| ARG | B:89 | B:89 | 27.0 | 0.12 | E | -103.1 | 126.6 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ARG | A:89 | A:89 | 32.0 | 0.142 | E | -96.9 | 120.5 | 32.0 | 0.142 | 0.0 |
FLB HOH |
9.400 3.960 |
O CG |
F2 O |
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| ARG | B:89 | E:89 | 34.0 | 0.151 | E | -96.8 | 120.3 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:89 | A:89 | 32.0 | 0.142 | E | -97.9 | 128.2 | 32.0 | 0.142 | 0.0 |
3TV HOH |
9.738 3.570 |
O N |
F15 O |
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| ARG | B:89 | B:89 | 27.0 | 0.12 | E | -88.3 | 121.1 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:89 | A:89 | 38.0 | 0.169 | E | -93.8 | 132.4 | 38.0 | 0.169 | 0.0 |
HOH |
3.858 |
CG |
O |
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| ARG | B:89 | B:89 | 27.0 | 0.12 | E | -93.2 | 125.9 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ARG | A:89 | A:89 | 32.0 | 0.142 | E | -98.4 | 128.3 | 32.0 | 0.142 | 0.0 |
3UG HOH |
9.473 3.859 |
O CG |
F14 O |
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| ARG | B:89 | B:89 | 32.0 | 0.142 | E | -92.5 | 124.1 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ARG | A:89 | A:89 | 30.0 | 0.133 | E | -95.5 | 129.2 | 30.0 | 0.133 | 0.0 |
V14 HOH |
9.953 3.955 |
O CG |
C14 O |
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| ARG | B:89 | B:89 | 30.0 | 0.133 | E | -91.6 | 127.8 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | ARG | A:89 | A:89 | 31.0 | 0.138 | E | -101.3 | 130.8 | 31.0 | 0.138 | 0.0 |
HOH |
4.067 |
NH2 |
O |
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| ARG | B:89 | B:89 | 31.0 | 0.138 | E | -97.4 | 121.6 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | ARG | A:89 | A:89 | 32.0 | 0.142 | E | -97.8 | 124.5 | 32.0 | 0.142 | 0.0 |
HOH |
4.050 |
CG |
O |
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| ARG | B:89 | B:89 | 31.0 | 0.138 | E | -101.7 | 130.1 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | ARG | A:89 | A:89 | 40.0 | 0.178 | E | -88.5 | 132.1 | 40.0 | 0.178 | 0.0 |
HOH |
2.973 |
NH1 |
O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | ARG | A:89 | A:89 | 39.0 | 0.173 | E | -88.1 | 126.9 | 39.0 | 0.173 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | ARG | A:85 | A:89 | 33.0 | 0.147 | E | -95.5 | 124.3 | 33.0 | 0.147 | 0.0 |
HOH |
4.083 |
CG |
O |
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| ARG | B:85 | B:89 | 37.0 | 0.164 | E | -88.5 | 123.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | ARG | A:90 | A:90 | 43.0 | 0.191 | E | -84.8 | 133.7 | |