Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86249290 | . | G | A | CCDS6237.1:NM_001128829.2:c.238Ctg>Ttg_NP_001122301.1:p.80L>L | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -112.9 | 132.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.664 |
CA |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -104.2 | 134.0 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -112.3 | 138.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.904 |
O |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -110.5 | 135.4 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -113.1 | 132.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.101 |
O |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -111.0 | 131.2 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -109.9 | 134.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.271 |
C |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -107.1 | 133.2 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -108.2 | 133.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.041 |
O |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -104.4 | 124.9 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -105.4 | 136.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.083 |
O |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -106.1 | 132.7 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -110.2 | 132.1 | 0.0 | 0.0 | 0.0 |
HOH |
8.268 |
N |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -106.2 | 134.1 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | LEU | A:80 | A:80 | 0.0 | 0.0 | E | -109.0 | 139.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.297 |
N |
O |
||
| LEU | B:80 | B:80 | 0.0 | 0.0 | E | -103.9 | 137.3 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -109.8 | 135.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.285 |
C |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -107.3 | 136.0 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -107.4 | 131.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.238 |
C |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -104.5 | 134.3 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -111.4 | 132.3 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:80 | B:79 | 1.0 | 0.006 | E | -120.5 | 136.4 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -112.8 | 133.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.511 |
C |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -106.9 | 130.8 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -114.1 | 132.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.265 |
C |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -102.7 | 132.7 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -112.5 | 134.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.482 |
CA |
O |
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| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -106.7 | 132.8 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -113.4 | 133.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.485 |
C |
O |
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| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -105.6 | 132.4 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -114.3 | 133.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.383 |
C |
O |
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| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -107.6 | 132.7 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -114.4 | 133.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.408 |
CA |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -107.1 | 132.6 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | LEU | A:80 | A:79 | 0.0 | 0.0 | E | -105.3 | 136.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.268 |
O |
O |
||
| LEU | B:80 | B:79 | 0.0 | 0.0 | E | -113.6 | 137.1 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 1.0 | 0.006 | E | -115.3 | 139.3 | 1.0 | 0.006 | 0.0 |
HOH |
5.458 |
O |
O |
||
| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 1.0 | 0.006 | E | -115.8 | 129.6 | 1.0 | 0.006 | 0.0 |
HOH |
5.141 |
O |
O |
||
| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -123.4 | 133.4 | 0.0 | 0.0 | 0.0 |
HG HG HG HOH |
7.267 8.235 9.408 7.535 |
CD1 CD1 CD1 N |
HG HG HG O |
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| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -104.2 | 130.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.298 |
C |
O |
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| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -113.0 | 132.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.857 |
O |
O |
||
| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | LEU | A:79 | A:79 | 1.0 | 0.006 | E | -126.1 | 132.4 | 1.0 | 0.006 | 0.0 |
IOD HOH |
8.003 3.772 |
CD1 N |
I O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -118.1 | 133.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.595 |
N |
O |
||
| LEU | B:79 | B:79 | 1.0 | 0.006 | E | -114.4 | 133.8 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -103.9 | 132.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.685 |
C |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -105.6 | 136.2 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -118.0 | 133.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.089 |
O |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -114.3 | 134.3 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -116.4 | 135.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.386 |
CA |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -112.5 | 136.7 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -122.3 | 135.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.533 |
CA |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -117.4 | 134.7 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -124.6 | 133.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.423 |
C |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -118.5 | 136.9 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -108.6 | 116.1 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -105.4 | 114.2 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -120.9 | 125.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.949 |
O |
O |
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| LEU | B:79 | E:79 | 0.0 | 0.0 | E | -121.1 | 125.7 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -110.4 | 135.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.321 |
C |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -105.4 | 133.3 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -111.8 | 137.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.327 |
CA |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -104.4 | 131.8 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -112.2 | 133.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.087 |
O |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -98.8 | 132.4 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -110.6 | 133.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.368 |
C |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -104.6 | 136.1 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -116.7 | 126.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.137 |
O |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -119.9 | 132.2 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -115.0 | 132.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.401 |
C |
O |
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| LEU | B:79 | B:79 | 0.0 | 0.0 | E | -111.4 | 138.0 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -119.5 | 132.1 | 0.0 | 0.0 | 0.0 |
HG HG CL HOH |
8.222 9.393 7.513 4.899 |
CD1 CD1 CD1 O |
HG HG CL O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | LEU | A:79 | A:79 | 0.0 | 0.0 | E | -116.6 | 132.4 | 0.0 | 0.0 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | LEU | A:75 | A:79 | 0.0 | 0.0 | E | -105.1 | 135.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.020 |
O |
O |
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| LEU | B:75 | B:79 | 0.0 | 0.0 | E | -111.0 | 139.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | LEU | A:80 | A:80 | 0.0 | 0.0 | E | -106.7 | 136.6 | |