Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr8 | 86250646 | . | C | A | CCDS6237.1:NM_001128829.2:c.70Gcc>Tcc_NP_001122301.1:p.24A>S | Homo sapiens carbonic anhydrase 1 (CA1), transcript variant 5, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5gmm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2017-05-24 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.3 | -27.8 | 3.0 | 0.026 | 0.0 |
HOH |
2.929 |
O |
O |
||
| ALA | B:24 | B:23 | 5.0 | 0.043 | G | -54.4 | -21.8 | NA | NA | NA | |||||||||||||
| 6evr | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-06-06 | ALA | A:24 | A:23 | 4.0 | 0.035 | G | -55.0 | -26.7 | 4.0 | 0.035 | 0.0 |
HOH |
2.876 |
O |
O |
||
| ALA | B:24 | B:23 | 5.0 | 0.043 | G | -53.1 | -27.5 | NA | NA | NA | |||||||||||||
| 6ex1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:24 | A:23 | 4.0 | 0.035 | G | -55.6 | -31.5 | 4.0 | 0.035 | 0.0 |
HOH |
2.795 |
O |
O |
||
| ALA | B:24 | B:23 | 5.0 | 0.043 | G | -55.6 | -26.1 | NA | NA | NA | |||||||||||||
| 6f3b | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.3 | -28.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.699 |
O |
O |
||
| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -55.6 | -31.3 | NA | NA | NA | |||||||||||||
| 6faf | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:24 | A:23 | 4.0 | 0.035 | G | -54.2 | -34.6 | 4.0 | 0.035 | 0.0 |
HOH |
5.089 |
N |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -49.1 | -31.1 | NA | NA | NA | |||||||||||||
| 6fag | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-10-10 | ALA | A:24 | A:23 | 2.0 | 0.017 | G | -57.7 | -36.4 | 2.0 | 0.017 | 0.0 |
HOH |
7.556 |
N |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -56.6 | -28.7 | NA | NA | NA | |||||||||||||
| 6g3v | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-11-28 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -62.7 | -26.1 | 3.0 | 0.026 | 0.0 |
HOH |
5.120 |
N |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -60.1 | -28.2 | NA | NA | NA | |||||||||||||
| 6hwz | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2018-12-26 | ALA | A:24 | A:24 | 3.0 | 0.026 | G | -52.2 | -37.7 | 3.0 | 0.026 | 0.0 |
HOH |
5.035 |
N |
O |
||
| ALA | B:24 | B:24 | 4.0 | 0.035 | G | -51.8 | -37.6 | NA | NA | NA | |||||||||||||
| 6i0j | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -55.8 | -29.6 | 3.0 | 0.026 | 0.0 |
HOH |
2.773 |
O |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -51.0 | -32.6 | NA | NA | NA | |||||||||||||
| 6i0l | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2019-11-20 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.7 | -30.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.793 |
O |
O |
||
| ALA | B:24 | B:23 | 5.0 | 0.043 | G | -55.5 | -28.6 | NA | NA | NA | |||||||||||||
| 6swm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-10-07 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -68.7 | -36.9 | 3.0 | 0.026 | 0.0 |
HOH |
9.091 |
C |
O |
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| ALA | B:24 | B:23 | 6.0 | 0.052 | G | -64.9 | -35.9 | NA | NA | NA | |||||||||||||
| 6xze | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -55.4 | -24.5 | 3.0 | 0.026 | 0.0 |
HOH |
2.772 |
O |
O |
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| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -57.2 | -24.3 | NA | NA | NA | |||||||||||||
| 6xzo | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 2.0 | 0.017 | G | -54.7 | -27.6 | 2.0 | 0.017 | 0.0 |
HOH |
2.712 |
O |
O |
||
| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -55.2 | -26.6 | NA | NA | NA | |||||||||||||
| 6xzs | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.5 | -25.3 | 3.0 | 0.026 | 0.0 |
HOH |
2.802 |
O |
O |
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| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -57.9 | -24.5 | NA | NA | NA | |||||||||||||
| 6xzx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.2 | -29.6 | 3.0 | 0.026 | 0.0 |
HOH |
2.680 |
O |
O |
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| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -57.3 | -24.2 | NA | NA | NA | |||||||||||||
| 6xzy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 2.0 | 0.017 | G | -58.3 | -27.5 | 2.0 | 0.017 | 0.0 |
HOH |
2.813 |
O |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -58.4 | -22.7 | NA | NA | NA | |||||||||||||
| 6y00 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2020-09-23 | ALA | A:24 | A:23 | 4.0 | 0.035 | G | -56.3 | -27.7 | 4.0 | 0.035 | 0.0 |
HOH |
2.746 |
O |
O |
||
| ALA | B:24 | B:23 | 3.0 | 0.026 | G | -54.5 | -25.2 | NA | NA | NA | |||||||||||||
| 7q0d | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ALA | A:24 | A:23 | 3.0 | 0.026 | G | -57.1 | -21.3 | 3.0 | 0.026 | 0.0 |
EDO HOH |
8.644 2.774 |
N O |
O1 O |
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| ALA | B:24 | B:23 | 4.0 | 0.035 | G | -55.3 | -25.5 | NA | NA | NA | |||||||||||||
| 1azm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -49.1 | -32.4 | 5.0 | 0.043 | 0.0 |
HOH |
3.071 |
O |
O |
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| 1bzm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -55.4 | -21.8 | 4.0 | 0.035 | 0.0 |
HOH |
2.718 |
O |
O |
||
| 1czm | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -52.3 | -25.2 | 5.0 | 0.043 | 0.0 |
HOH |
3.079 |
O |
O |
||
| 1hcb | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -55.5 | -31.8 | 4.0 | 0.035 | 0.0 |
HOH |
2.661 |
O |
O |
||
| 1hug | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -53.0 | -23.8 | 5.0 | 0.043 | 0.0 |
HOH |
3.962 |
CB |
O |
||
| 1huh | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
1994-04-30 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -50.5 | -28.7 | 4.0 | 0.035 | 0.0 |
IOD HOH |
6.945 4.220 |
O CB |
I O |
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| 2foy | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-04-04 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -58.2 | -21.8 | 5.0 | 0.043 | 0.0 |
HOH |
2.800 |
O |
O |
||
| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -59.6 | -25.6 | NA | NA | NA | |||||||||||||
| 2fw4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2006-08-08 | ALA | A:23 | A:23 | 2.0 | 0.017 | G | -49.1 | -32.0 | 2.0 | 0.017 | 0.0 |
HOH |
4.598 |
O |
O |
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| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -49.8 | -26.7 | NA | NA | NA | |||||||||||||
| 2nmx | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ALA | A:23 | A:23 | 2.0 | 0.017 | G | -57.1 | -23.5 | 2.0 | 0.017 | 0.0 |
HOH |
2.689 |
O |
O |
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| ALA | B:23 | B:23 | 2.0 | 0.017 | G | -59.6 | -25.0 | NA | NA | NA | |||||||||||||
| 2nn1 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-04-24 | ALA | A:23 | A:23 | 2.0 | 0.017 | G | -54.8 | -25.9 | 2.0 | 0.017 | 0.0 |
HOH |
2.799 |
O |
O |
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| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -57.0 | -25.7 | NA | NA | NA | |||||||||||||
| 2nn7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-05-08 | ALA | A:23 | A:23 | 2.0 | 0.017 | G | -56.1 | -26.4 | 2.0 | 0.017 | 0.0 |
HOH |
2.728 |
O |
O |
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| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -55.8 | -30.8 | NA | NA | NA | |||||||||||||
| 3lxe | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2010-07-21 | ALA | A:23 | A:23 | 2.0 | 0.017 | G | -63.0 | -20.3 | 2.0 | 0.017 | 0.0 |
HOH |
2.817 |
O |
O |
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| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -59.7 | -17.4 | NA | NA | NA | |||||||||||||
| 3w6h | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ALA | A:23 | A:23 | 1.0 | 0.009 | G | -58.5 | -16.2 | 1.0 | 0.009 | 0.0 | ||||||
| ALA | B:23 | B:23 | 2.0 | 0.017 | G | -57.4 | -17.0 | NA | NA | NA | |||||||||||||
| 3w6i | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2013-03-13 | ALA | A:23 | A:23 | 3.0 | 0.026 | G | -56.9 | -33.0 | 3.0 | 0.026 | 0.0 |
HOH |
5.711 |
O |
O |
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| ALA | B:23 | E:23 | 3.0 | 0.026 | G | -57.1 | -32.9 | NA | NA | NA | |||||||||||||
| 4wr7 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:23 | A:23 | 3.0 | 0.026 | G | -55.7 | -20.5 | 3.0 | 0.026 | 0.0 |
HOH |
2.676 |
O |
O |
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| ALA | B:23 | B:23 | 4.0 | 0.035 | G | -50.7 | -31.2 | NA | NA | NA | |||||||||||||
| 4wup | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -54.2 | -30.0 | 4.0 | 0.035 | 0.0 |
HOH |
2.735 |
O |
O |
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| ALA | B:23 | B:23 | 5.0 | 0.043 | G | -57.2 | -24.0 | NA | NA | NA | |||||||||||||
| 4wuq | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -52.3 | -33.8 | 4.0 | 0.035 | 0.0 |
HOH |
2.772 |
O |
O |
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| ALA | B:23 | B:23 | 4.0 | 0.035 | G | -55.6 | -24.1 | NA | NA | NA | |||||||||||||
| 5e2m | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2016-10-05 | ALA | A:23 | A:23 | 3.0 | 0.026 | G | -52.8 | -31.0 | 3.0 | 0.026 | 0.0 |
HOH |
2.829 |
O |
O |
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| ALA | B:23 | B:23 | 3.0 | 0.026 | G | -49.5 | -27.5 | NA | NA | NA | |||||||||||||
| 1j9w | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-06-13 | ALA | A:23 | A:23 | 4.0 | 0.035 | G | -46.7 | -41.0 | 4.0 | 0.035 | 0.0 |
HOH |
2.912 |
O |
O |
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| ALA | B:23 | B:23 | 4.0 | 0.035 | G | -50.0 | -27.1 | NA | NA | NA | |||||||||||||
| 1jv0 | 1 | P00915 | 99.62 | 0.0 |
X-RAY |
2001-09-19 | ALA | A:23 | A:23 | 3.0 | 0.026 | G | -59.5 | -32.1 | 3.0 | 0.026 | 0.0 |
HOH |
3.234 |
O |
O |
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| ALA | B:23 | B:23 | 5.0 | 0.043 | G | -49.1 | -33.7 | NA | NA | NA | |||||||||||||
| 1crm | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1995-02-07 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -53.2 | -26.6 | 5.0 | 0.043 | 0.0 |
HOH |
3.394 |
O |
O |
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| 2cab | 1 | P00915 | 99.23 | 0.0 |
X-RAY |
1984-02-02 | ALA | A:23 | A:23 | 5.0 | 0.043 | G | -53.4 | -32.0 | 5.0 | 0.043 | 0.0 | ||||||
| 2it4 | 1 | P00915 | 100.0 | 0.0 |
X-RAY |
2007-09-11 | ALA | A:19 | A:23 | 3.0 | 0.026 | G | -58.1 | -29.9 | 3.0 | 0.026 | 0.0 |
HOH |
3.863 |
CB |
O |
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| ALA | B:19 | B:23 | 4.0 | 0.035 | G | -50.1 | -36.0 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00915-f1 | 1 | P00915 | 100.0 | 0.0 | ALA | A:24 | A:24 | 4.0 | 0.035 | G | -56.0 | -24.1 | |