Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 123725926 . T A CCDS6826.1:NM_001735.2:c.4311gaA>gaT_NP_001726.2:p.1437E>D Homo sapiens complement C5 (C5), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3prx 1 P01031 100.0 0.0 X-RAY
 2011-01-19 GLU A:1437 A:1437 65.0 0.342 H -60.4 -42.6 65.0 0.342 0.0
GLU C:1437 C:1437 61.0 0.321 H -61.8 -43.4 NA NA NA
3pvm 1 P01031 100.0 0.0 X-RAY
 2011-01-19 GLU A:1437 A:1437 62.0 0.326 H -52.1 -45.1 62.0 0.326 0.0
GLU C:1437 C:1437 59.0 0.311 H -50.9 -46.5 NA NA NA
5i5k 1 P01031 100.0 0.0 X-RAY
 2016-03-16 GLU A:1437 B:1437 57.0 0.3 H -62.4 -34.9 57.0 0.3 0.0
GLU D:1437 A:1437 58.0 0.305 H -61.7 -33.6 NA NA NA
7ad6 1 P01031 100.0 0.0 X-RAY
 2021-03-10 GLU A:1437 A:1437 143.0 0.753 H -69.6 -34.9 92.0 0.484 0.269 B:P01031:0.242
 CYS
 5.781
 O
 CA
GLU B:1437 NA:NA DO NA DO DO DO NA NA NA
7ad7 1 P01031 100.0 0.0 X-RAY
 2021-03-10 GLU A:1437 NA:NA DO NA DO DO DO NA NA NA
GLU B:1437 A:1437 128.0 0.674 H -68.8 -37.9 122.0 0.642 0.032 CYS
HOH
 4.658
4.991
 OE2
O
 O
O
3cu7 1 P01031 99.94 0.0 X-RAY
 2008-06-10 GLU A:1437 A:1437 51.0 0.268 H -63.0 -38.8 51.0 0.268 0.0 CD
 5.754
 OE1
 CD
GLU B:1437 B:1437 49.0 0.258 H -63.1 -38.6 NA NA NA
3kls 1 P01031 99.94 0.0 X-RAY
 2009-11-24 GLU A:1437 A:1437 48.0 0.253 H -67.5 -41.0 48.0 0.253 0.0 CD
 5.912
 OE1
 CD
GLU C:1437 B:1437 50.0 0.263 H -66.3 -41.0 NA NA NA
3km9 1 P01031 99.94 0.0 X-RAY
 2009-12-01 GLU A:1437 A:1437 57.0 0.3 H -74.8 -23.8 57.0 0.3 0.0
GLU C:1437 B:1437 59.0 0.311 H -63.5 -34.6 NA NA NA
4e0s 1 P01031 99.94 0.0 X-RAY
 2012-04-18 GLU A:1437 A:1437 123.0 0.647 H -54.5 -51.2 123.0 0.647 0.0
7nyc 6 P01031 100.0 0.0 EM
 2021-10-06 GLU G:1419 A:1419 149.0 0.784 H -68.0 -25.8 149.0 0.784 0.0
7nyd 7 P01031 100.0 0.0 EM
 2021-10-06 GLU H:1419 A:1419 149.0 0.784 H -69.9 -15.3 149.0 0.784 0.0
6i2x 2 P01031 100.0 0.0 ELECTRON CRYSTALLOGRAPHY
 2019-06-26 GLU B:760 A:1437 120.0 0.632 H -71.8 -17.6 84.0 0.442 0.19 A:P01031:0.189
 H1H
 8.374
 O
 O31
6rqj 1 P01031 100.0 0.0 EM
 2020-01-08 GLU A:760 A:1437 120.0 0.632 H -68.8 -33.5 69.0 0.363 0.269 D:P01031:0.268
5hcc 2 P01031 100.0 0.0 X-RAY
 2016-03-30 GLU B:759 A:1437 127.0 0.668 H -67.4 -42.0 112.0 0.589 0.079 A:P01031:0.074
 CYS
HOH
 5.118
8.815
 O
O
 N
O
5hcd 2 P01031 100.0 0.0 X-RAY
 2016-03-30 GLU B:759 A:1437 127.0 0.668 H -67.0 -42.1 116.0 0.611 0.057 A:P01031:0.053
 CYS
 5.241
 O
 N
5hce 2 P01031 100.0 0.0 X-RAY
 2016-03-30 GLU B:759 A:1437 128.0 0.674 H -66.6 -42.4 113.0 0.595 0.079 A:P01031:0.074
 CYS
 5.129
 O
 N
4a5w 1 P01031 100.0 0.0 X-RAY
 2012-03-14 GLU A:1341 A:1437 137.0 0.721 H -62.6 -29.9 137.0 0.721 0.0
6h03 1 P01031 100.0 0.0 EM
 2018-12-19 GLU A:1341 NA:NA DO NA DO DO DO NA NA NA
6h04 2 P01031 100.0 0.0 EM
 2018-12-19 GLU S:1341 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01031-f1 1 P01031 100.0 0.0 GLU A:1437 A:1437 43.0 0.226 H -59.1 -32.9