Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 130914190 . C A CCDS6892.1:NM_005564.3:c.361Cct>Act_NP_005555.2:p.121P>T Homo sapiens lipocalin 2 (LCN2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3hwe 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 PRO A:121 A:101 115.0 0.793 T -59.6 135.6 115.0 0.793 0.0 RKS
RKS
 8.079
5.256
 O
O
 O9
O8
PRO B:121 B:101 126.0 0.869 T -53.1 122.8 NA NA NA
PRO C:121 C:101 119.0 0.821 T -61.1 136.8 NA NA NA
3hwf 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 PRO A:121 A:101 123.0 0.848 T -62.3 131.3 123.0 0.848 0.0 TC2
 6.182
 O
 O22
PRO B:121 B:101 128.0 0.883 T -48.0 131.4 NA NA NA
PRO C:121 C:101 118.0 0.814 T -72.5 142.5 NA NA NA
3hwg 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 PRO A:121 A:101 117.0 0.807 T -64.5 129.6 117.0 0.807 0.0 QED
HOH
 6.444
8.223
 O
O
 O10
O
PRO B:121 B:101 134.0 0.924 T -58.1 121.8 NA NA NA
PRO C:121 C:101 123.0 0.848 T -66.1 127.9 NA NA NA
3u0d 1 P80188 99.49 4e-148 X-RAY
 2011-10-12 PRO A:121 A:101 124.0 0.855 T -62.8 137.3 124.0 0.855 0.0 DBH
HOH
 7.316
3.920
 O
CB
 O17
O
PRO B:121 B:101 125.0 0.862 T -73.5 137.6 NA NA NA
PRO C:121 C:101 127.0 0.876 T -68.9 132.7 NA NA NA
PRO D:121 D:101 122.0 0.841 T -46.4 130.6 NA NA NA
3cbc 1 P80188 98.99 1e-147 X-RAY
 2008-09-09 PRO A:121 A:101 125.0 0.862 T -60.6 126.5 NA NA NA
PRO B:121 B:101 124.0 0.855 T -72.9 129.8 124.0 0.855 0.0 HOH
 7.278
 N
 O
PRO C:121 C:101 127.0 0.876 T -75.3 128.4 NA NA NA
3cmp 1 P80188 98.99 3e-147 X-RAY
 2009-05-12 PRO A:121 A:101 122.0 0.841 T -52.0 115.3 122.0 0.841 0.0 EB4
HOH
 6.681
7.313
 O
C
 C14
O
PRO B:121 B:101 129.0 0.89 T -72.6 129.7 NA NA NA
PRO C:121 C:101 126.0 0.869 T -50.6 126.3 NA NA NA
3i0a 1 P80188 98.99 3e-147 X-RAY
 2010-06-09 PRO A:121 A:101 124.0 0.855 T -59.4 124.6 124.0 0.855 0.0 2DS
 5.041
 O
 O7
PRO B:121 B:101 129.0 0.89 S -77.0 127.7 NA NA NA
PRO C:121 C:101 127.0 0.876 T -61.5 129.4 NA NA NA
3hwd 1 P80188 98.48 1e-146 X-RAY
 2010-06-02 PRO A:121 A:101 121.0 0.834 T -67.4 128.7 121.0 0.834 0.0 HOH
 4.236
 C
 O
PRO B:121 B:101 134.0 0.924 T -52.2 124.7 NA NA NA
PRO C:121 C:101 120.0 0.828 T -68.3 129.5 NA NA NA
3by0 1 P80188 98.48 9e-146 X-RAY
 2008-09-09 PRO A:121 A:101 123.0 0.848 T -64.8 125.8 123.0 0.848 0.0 DBH
HOH
 7.403
7.128
 N
O
 C12
O
PRO B:121 B:101 128.0 0.883 T -73.1 129.1 NA NA NA
PRO C:121 C:101 117.0 0.807 T -62.4 132.2 NA NA NA
1dfv 1 P80188 100.0 2e-132 X-RAY
 2000-03-06 PRO A:101 A:101 125.0 0.862 T -56.0 115.4 125.0 0.862 0.0 HOH
 4.341
 N
 O
PRO B:101 B:101 123.0 0.848 T -57.0 122.4 NA NA NA
1l6m 1 P80188 98.88 3e-132 X-RAY
 2003-03-11 PRO A:103 A:101 119.0 0.821 T -51.0 131.7 119.0 0.821 0.0 DBH
 5.856
 O
 C12
PRO B:103 B:101 127.0 0.876 T -60.6 136.9 NA NA NA
PRO C:103 C:101 121.0 0.834 T -54.0 120.4 NA NA NA
4k19 1 P80188 98.88 3e-132 X-RAY
 2013-07-31 PRO A:103 A:101 122.0 0.841 T -59.9 123.6 122.0 0.841 0.0 1OD
 5.176
 O
 O20
PRO B:103 B:101 123.0 0.848 T -62.4 130.7 NA NA NA
PRO C:103 C:101 128.0 0.883 T -59.7 136.7 NA NA NA
4zfx 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 124.0 0.855 T -68.6 135.2 124.0 0.855 0.0 EB4
 9.802
 O
 C30
PRO B:103 B:101 121.0 0.834 T -67.1 136.0 121.0 0.834 0.0
PRO C:103 C:101 123.0 0.848 T -66.2 135.7 123.0 0.848 0.0
4zhc 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 117.0 0.807 T -60.8 129.7 117.0 0.807 0.0 HOH
 7.169
 C
 O
PRO B:103 B:101 123.0 0.848 T -59.7 130.9 NA NA NA
PRO C:103 C:101 123.0 0.848 T -58.6 129.8 NA NA NA
4zhd 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 115.0 0.793 T -59.5 129.4 115.0 0.793 0.0
PRO B:103 B:101 131.0 0.903 T -55.9 128.7 NA NA NA
PRO C:103 C:101 122.0 0.841 T -56.8 129.0 NA NA NA
4zhf 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 125.0 0.862 T -64.2 137.6 125.0 0.862 0.0 4OL
 7.163
 CD
 C42
PRO B:103 B:101 121.0 0.834 T -65.7 137.0 NA NA NA
PRO C:103 C:101 123.0 0.848 T -64.1 136.3 NA NA NA
PRO D:103 D:101 121.0 0.834 T -65.7 138.4 NA NA NA
PRO E:103 E:101 126.0 0.869 T -66.1 138.2 NA NA NA
PRO F:103 F:101 127.0 0.876 T -64.6 138.4 NA NA NA
4zhg 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 122.0 0.841 T -61.6 139.0 122.0 0.841 0.0 4OL
 7.254
 O
 C42
PRO B:103 B:101 119.0 0.821 T -63.2 139.4 NA NA NA
PRO C:103 C:101 123.0 0.848 T -65.0 139.8 NA NA NA
PRO D:103 D:101 122.0 0.841 T -62.2 138.3 NA NA NA
PRO E:103 E:101 128.0 0.883 T -66.6 141.8 NA NA NA
PRO F:103 F:101 129.0 0.89 T -63.7 139.7 NA NA NA
4zhh 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 PRO A:103 A:101 119.0 0.821 T -61.3 133.8 119.0 0.821 0.0 4OL
HOH
 7.428
3.072
 N
O
 C42
O
PRO B:103 B:101 120.0 0.828 T -60.3 131.9 NA NA NA
PRO C:103 C:101 119.0 0.821 T -59.3 132.5 NA NA NA
PRO D:103 D:101 122.0 0.841 T -59.0 133.2 NA NA NA
PRO E:103 E:101 127.0 0.876 T -61.3 135.8 NA NA NA
PRO F:103 F:101 128.0 0.883 T -62.1 135.5 NA NA NA
5khp 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 PRO A:103 A:101 121.0 0.834 T -71.6 133.2 121.0 0.834 0.0 SO4
SO4
HOH
 3.425
9.924
8.509
 CA
CD
CD
 O1
O4
O
PRO B:103 B:101 124.0 0.855 T -68.3 133.0 NA NA NA
PRO C:103 C:101 127.0 0.876 T -67.1 134.3 NA NA NA
5kic 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 PRO A:103 A:101 126.0 0.869 T -68.3 142.2 126.0 0.869 0.0 4OL
 5.845
 O
 C42
PRO B:103 B:101 126.0 0.869 T -64.4 141.6 NA NA NA
PRO C:103 C:101 125.0 0.862 T -68.2 141.2 NA NA NA
5kid 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 PRO A:103 A:101 122.0 0.841 T -64.8 134.5 122.0 0.841 0.0 HOH
 9.925
 N
 O
PRO B:103 B:101 121.0 0.834 T -61.7 133.7 NA NA NA
PRO C:103 C:101 120.0 0.828 T -64.4 133.9 NA NA NA
3tzs 1 P80188 98.88 4e-132 X-RAY
 2011-10-12 PRO A:102 A:101 130.0 0.897 T -64.9 130.5 130.0 0.897 0.0 HOH
 4.771
 CA
 O
PRO B:102 B:101 124.0 0.855 T -62.3 136.7 NA NA NA
PRO C:102 C:101 129.0 0.89 T -58.2 130.1 NA NA NA
1x71 1 P80188 99.44 5e-132 X-RAY
 2005-01-18 PRO A:101 A:101 120.0 0.828 T -58.7 124.0 120.0 0.828 0.0 HOH
 6.820
 O
 O
PRO B:101 B:101 125.0 0.862 T -53.7 127.5 NA NA NA
PRO C:101 C:101 115.0 0.793 T -44.4 114.6 NA NA NA
1x89 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 PRO A:101 A:101 118.0 0.814 T -54.9 117.4 118.0 0.814 0.0 CM1
 8.296
 O
 C42
PRO B:101 B:101 123.0 0.848 T -61.4 128.5 NA NA NA
PRO C:101 C:101 123.0 0.848 T -54.7 126.1 NA NA NA
1x8u 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 PRO A:101 A:101 121.0 0.834 T -68.3 121.3 121.0 0.834 0.0 CM2
 8.615
 O
 C42
PRO B:101 B:101 123.0 0.848 T -61.1 126.7 NA NA NA
PRO C:101 C:101 119.0 0.821 T -51.2 131.6 NA NA NA
3fw4 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 PRO A:101 A:101 121.0 0.834 T -61.8 130.5 121.0 0.834 0.0 GOL
CL
CL
HOH
 7.955
8.955
5.335
3.515
 CD
CD
O
CA
 C1
CL
CL
O
PRO B:101 B:101 136.0 0.938 S -56.1 -26.5 NA NA NA
PRO C:101 C:101 116.0 0.8 T -58.5 126.7 NA NA NA
3fw5 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 PRO A:101 A:101 121.0 0.834 T -57.8 125.3 121.0 0.834 0.0 CL
HOH
 9.504
7.313
 CD
C
 CL
O
PRO B:101 B:101 132.0 0.91 T -62.8 124.5 NA NA NA
PRO C:101 C:101 115.0 0.793 T -61.7 125.6 NA NA NA
3k3l 1 P80188 99.44 5e-132 X-RAY
 2010-08-18 PRO A:101 A:101 118.0 0.814 T -59.7 125.3 118.0 0.814 0.0 DBS
DBH
HOH
 9.908
6.343
7.208
 O
O
C
 O13
C15
O
PRO B:101 B:101 133.0 0.917 T -65.8 118.0 NA NA NA
PRO C:101 C:101 116.0 0.8 T -69.6 129.6 NA NA NA
3pec 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 PRO A:101 A:101 112.0 0.772 T -69.4 130.2 112.0 0.772 0.0 HOH
 3.399
 C
 O
PRO B:101 B:101 126.0 0.869 T -69.2 130.3 NA NA NA
PRO C:101 C:101 116.0 0.8 T -68.7 130.2 NA NA NA
3ped 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 PRO A:101 A:101 123.0 0.848 T -68.4 131.0 123.0 0.848 0.0 ZYF
HOH
 8.073
4.522
 O
N
 C41
O
PRO B:101 B:101 124.0 0.855 T -77.8 142.0 NA NA NA
PRO C:101 C:101 125.0 0.862 T -58.0 134.6 NA NA NA
3tf6 1 P80188 98.88 5e-132 X-RAY
 2011-09-07 PRO A:102 A:101 117.0 0.807 T -66.0 131.9 117.0 0.807 0.0 HOH
 7.017
 C
 O
PRO B:102 B:101 126.0 0.869 T -63.1 133.1 NA NA NA
PRO C:102 C:101 120.0 0.828 T -64.4 133.1 NA NA NA
6o5d 1 P80188 99.43 7e-129 X-RAY
 2019-09-11 PRO A:97 A:101 120.0 0.828 T -55.9 128.6 120.0 0.828 0.0 SO4
HOH
 9.944
7.117
 O
C
 O4
O
PRO B:97 B:101 122.0 0.841 T -55.5 128.6 NA NA NA
PRO C:97 C:101 121.0 0.834 T -55.9 128.0 NA NA NA
5mhh 1 P80188 96.63 1e-127 X-RAY
 2017-10-11 PRO A:101 A:101 119.0 0.821 T -63.7 131.9 119.0 0.821 0.0 HOH
 5.051
 CD
 O
6qmu 1 P80188 96.63 1e-127 X-RAY
 2019-08-28 PRO A:101 A:101 123.0 0.848 T -61.1 135.5 123.0 0.848 0.0 HOH
 4.696
 CA
 O
PRO B:101 B:101 122.0 0.841 T -63.1 132.6 NA NA NA
3t1d 1 P80188 97.78 1e-120 X-RAY
 2011-08-17 PRO A:121 A:101 119.0 0.821 T -62.8 128.1 119.0 0.821 0.0 TD1
HOH
 8.874
4.620
 O
C
 N27
O
PRO B:121 B:101 119.0 0.821 T -58.0 119.9 NA NA NA
PRO C:121 C:101 123.0 0.848 T -63.1 139.6 NA NA NA
3dsz 1 ? 91.57 4e-120 X-RAY
 2009-05-19 PRO A:101 A:101 130.0 0.897 T -49.9 123.2 130.0 0.897 0.0 LIZ
HOH
 8.802
3.769
 CD
C
 C29
O
PRO B:101 B:101 119.0 0.821 T -54.5 128.6 NA NA NA
3dtq 1 P80188 91.57 4e-120 X-RAY
 2009-05-12 PRO A:101 A:101 120.0 0.828 T -49.7 122.6 120.0 0.828 0.0 HOH
 4.030
 CA
 O
PRO B:101 B:101 118.0 0.814 S -79.8 128.7 NA NA NA
PRO C:101 C:101 119.0 0.821 T -41.7 106.2 NA NA NA
5n47 1 P80188 90.45 6e-118 X-RAY
 2018-02-14 PRO A:101 A:101 121.0 0.834 T -67.3 139.0 121.0 0.834 0.0
PRO C:101 C:101 124.0 0.855 T -75.2 104.0 NA NA NA
PRO E:101 E:101 120.0 0.828 T -81.2 130.8 NA NA NA
1qqs 1 P80188 97.7 4e-116 X-RAY
 2000-04-21 PRO A:98 A:101 126.0 0.869 T -47.7 -19.6 126.0 0.869 0.0 DKA
NAG
MAN
HOH
 9.453
9.817
9.436
7.150
 N
C
C
N
 C10
O4
O2
O
5jr8 1 P80188 94.38 3e-115 X-RAY
 2016-09-28 PRO A:101 A:101 132.0 0.91 T -71.5 128.0 132.0 0.91 0.0 HOH
 4.796
 N
 O
PRO B:101 B:101 132.0 0.91 T -71.9 125.2 NA NA NA
4mvl 1 P80188 89.33 1e-114 X-RAY
 2015-08-12 PRO A:101 A:101 126.0 0.869 S -50.4 144.0 126.0 0.869 0.0
PRO B:101 B:101 119.0 0.821 S -68.1 132.4 NA NA NA
PRO C:101 C:101 117.0 0.807 T -66.5 143.7 NA NA NA
PRO D:101 D:101 125.0 0.862 S -57.5 144.7 NA NA NA
4mvi 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 PRO A:101 A:101 145.0 1.0 T -12.2 -75.6 145.0 1.0 0.0 HOH
 6.422
 O
 O
4mvk 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 PRO A:101 A:101 133.0 0.917 S -3.1 -80.5 133.0 0.917 0.0 HOH
 6.525
 O
 O
5n48 1 P80188 88.2 1e-113 X-RAY
 2018-02-14 PRO A:101 A:101 114.0 0.786 T -97.9 1.3 20.0 0.138 0.648 B:P02751:0.648
 HOH
 3.117
 CG
 O
PRO C:101 C:101 107.0 0.738 T -89.4 -7.6 NA NA NA
4gh7 1 P80188 88.2 1e-113 X-RAY
 2012-12-26 PRO A:101 A:101 109.0 0.752 T -54.3 131.5 20.0 0.138 0.614 B:P02751:0.614
 HOH
 2.879
 O
 O
PRO C:101 C:101 110.0 0.759 T -60.8 124.8 NA NA NA
6s8v 1 P80188 88.2 9e-113 X-RAY
 2020-03-04 PRO A:101 A:101 140.0 0.966 T -61.2 -24.4 140.0 0.966 0.0 HOH
 3.364
 CD
 O
PRO C:101 C:101 122.0 0.841 S -84.0 -19.3 NA NA NA
6sua 1 P80188 88.76 2e-112 X-RAY
 2020-06-17 LEU A:101 A:101 163.0 0.959 S -69.7 -43.9 163.0 0.959 0.0 SO4
SO4
HOH
 6.435
7.874
9.452
 O
C
CD1
 O1
O3
O
LEU C:101 C:101 164.0 0.965 S -70.0 -43.9 NA NA NA
4iaw 1 P80188 87.08 3e-112 X-RAY
 2013-06-19 PRO A:101 A:101 121.0 0.834 T -66.9 135.8 121.0 0.834 0.0 HOH
 4.622
 N
 O
PRO B:101 B:101 127.0 0.876 T -73.8 129.2 NA NA NA
PRO C:101 C:101 109.0 0.752 T -67.5 100.8 NA NA NA
6z2c 1 P80188 88.2 4e-111 X-RAY
 2021-05-26 PRO A:101 A:101 130.0 0.897 -72.2 -15.4 130.0 0.897 0.0 Q5E
HOH
 5.876
4.466
 C
CD
 OAY
O
PRO B:101 B:101 120.0 0.828 T -72.0 -15.7 NA NA NA
PRO C:101 C:101 123.0 0.848 S -71.2 -16.9 NA NA NA
6z6z 1 P80188 86.52 3e-110 X-RAY
 2021-06-09 PRO A:102 A:101 139.0 0.959 -82.8 -6.7 139.0 0.959 0.0 CA
HOH
 6.563
3.573
 N
CD
 CA
O
4qae 2 P80188 85.39 3e-109 X-RAY
 2015-05-06 PRO G:101 A:101 142.0 0.979 T -67.7 2.6 142.0 0.979 0.0 HOH
 5.268
 N
 O
PRO H:101 B:101 135.0 0.931 S -55.9 -64.3 NA NA NA
PRO I:101 NA:NA DO NA DO DO DO NA NA NA
PRO J:101 NA:NA DO NA DO DO DO NA NA NA
PRO K:101 NA:NA DO NA DO DO DO NA NA NA
PRO L:101 NA:NA DO NA DO DO DO NA NA NA
3bx7 2 ? 83.15 4e-108 X-RAY
 2009-01-20 GLY B:101 A:101 37.0 0.493 116.9 160.2 37.0 0.493 0.0
3bx8 1 ? 83.15 4e-108 X-RAY
 2009-01-20 GLY A:101 NA:NA DO NA DO DO DO NA NA NA
GLY B:101 NA:NA DO NA DO DO DO NA NA NA
GLY C:101 NA:NA DO NA DO DO DO NA NA NA
GLY D:101 NA:NA DO NA DO DO DO NA NA NA
GLY E:101 NA:NA DO NA DO DO DO NA NA NA
GLY F:101 NA:NA DO NA DO DO DO NA NA NA
GLY G:101 NA:NA DO NA DO DO DO NA NA NA
GLY H:101 NA:NA DO NA DO DO DO NA NA NA
5nkn 1 P80188 86.21 2e-106 X-RAY
 2018-04-04 PRO A:97 A:101 130.0 0.897 S -33.8 -57.4 130.0 0.897 0.0 LOC
 9.060
 C
 C13
6gqz 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 PRO A:97 A:101 121.0 0.834 T -57.6 129.7 121.0 0.834 0.0 HOH
 2.526
 O
 O
PRO B:97 B:101 115.0 0.793 T -61.9 129.9 NA NA NA
6gr0 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 PRO A:97 A:101 120.0 0.828 T -57.6 129.5 120.0 0.828 0.0 F8W
HOH
 5.951
8.305
 CD
O
 OBD
O
PRO B:97 B:101 120.0 0.828 T -55.7 129.7 NA NA NA
PRO C:97 C:101 117.0 0.807 T -57.9 129.7 NA NA NA
4iax 1 P80188 81.46 3e-103 X-RAY
 2013-06-19 PRO A:101 A:101 128.0 0.883 T -65.8 123.1 128.0 0.883 0.0 HOH
 4.599
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p80188-f1 1 P80188 100.0 1e-149 PRO A:121 A:121 127.0 0.876 T -54.3 131.1