Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 130914272 . A C CCDS6892.1:NM_005564.3:c.443cAa>cCa_NP_005555.2:p.148Q>P Homo sapiens lipocalin 2 (LCN2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3hwe 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLN A:148 A:128 125.0 0.694 T 49.0 42.2 125.0 0.694 0.0 RKS
RKS
HOH
 5.560
5.342
5.711
 OE1
NE2
C
 O9
O8
O
GLN B:148 B:128 130.0 0.722 S 71.3 34.8 NA NA NA
GLN C:148 C:128 139.0 0.772 T 52.2 46.9 NA NA NA
3hwf 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLN A:148 A:128 84.0 NA T 51.9 28.0 84.0 NA NA TC2
NA
 7.757
6.802
 CD
C
 O22
NA
GLN B:148 B:128 119.0 0.661 T 63.8 30.8 NA NA NA
GLN C:148 C:128 152.0 0.844 T 46.4 46.2 NA NA NA
3hwg 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLN A:148 A:128 129.0 0.717 T 50.7 45.3 129.0 0.717 0.0 QED
NA
HOH
 6.338
6.305
2.728
 OE1
NE2
NE2
 O10
NA
O
GLN B:148 B:128 103.0 NA T 59.2 37.4 NA NA NA
GLN C:148 C:128 103.0 NA T 50.4 43.7 NA NA NA
3u0d 1 P80188 99.49 4e-148 X-RAY
 2011-10-12 GLN A:148 A:128 142.0 0.789 T 45.3 50.0 142.0 0.789 0.0 DBH
HOH
 8.995
2.660
 N
NE2
 O17
O
GLN B:148 B:128 132.0 0.733 T 58.5 37.9 NA NA NA
GLN C:148 C:128 136.0 0.756 T 32.8 42.9 NA NA NA
GLN D:148 D:128 132.0 0.733 T 41.3 49.8 NA NA NA
3cbc 1 P80188 98.99 1e-147 X-RAY
 2008-09-09 GLN A:148 A:128 113.0 0.628 T 55.4 36.1 NA NA NA
GLN B:148 B:128 130.0 0.722 T 54.5 44.0 130.0 0.722 0.0 HOH
 3.223
 N
 O
GLN C:148 C:128 123.0 0.683 T 58.2 38.1 NA NA NA
3cmp 1 P80188 98.99 3e-147 X-RAY
 2009-05-12 GLN A:148 A:128 126.0 0.7 T 57.8 33.5 126.0 0.7 0.0 EB4
HOH
 6.677
3.168
 N
N
 O8
O
GLN B:148 B:128 57.0 NA T 53.0 47.1 NA NA NA
GLN C:148 C:128 144.0 0.8 S 53.8 52.0 NA NA NA
3i0a 1 P80188 98.99 3e-147 X-RAY
 2010-06-09 GLN A:148 A:128 81.0 NA T 47.8 41.9 81.0 NA NA 3ET
2DS
 9.054
7.647
 N
N
 O14
O7
GLN B:148 B:128 58.0 NA S -72.6 -54.6 NA NA NA
GLN C:148 C:128 128.0 0.711 T 48.7 42.9 NA NA NA
3hwd 1 P80188 98.48 1e-146 X-RAY
 2010-06-02 GLN A:148 A:128 106.0 0.589 T 54.6 44.0 106.0 0.589 0.0 HOH
 6.971
 NE2
 O
GLN B:148 B:128 79.0 NA T 58.5 37.5 NA NA NA
GLN C:148 C:128 145.0 0.806 T 55.9 44.3 NA NA NA
3by0 1 P80188 98.48 9e-146 X-RAY
 2008-09-09 GLN A:148 A:128 135.0 0.75 T 48.3 43.2 135.0 0.75 0.0 DBS
DBH
HOH
 8.351
9.100
2.945
 NE2
N
N
 O13
C9
O
GLN B:148 B:128 141.0 0.783 T 54.2 43.3 NA NA NA
GLN C:148 C:128 129.0 0.717 T 51.4 40.0 NA NA NA
1dfv 1 P80188 100.0 2e-132 X-RAY
 2000-03-06 GLN A:128 A:128 121.0 0.672 T 58.1 16.5 121.0 0.672 0.0 HOH
 5.931
 C
 O
GLN B:128 B:128 131.0 0.728 T 71.1 -5.0 NA NA NA
1l6m 1 P80188 98.88 3e-132 X-RAY
 2003-03-11 GLN A:130 A:128 99.0 0.55 T 46.7 41.2 99.0 0.55 0.0 DBH
DBS
HOH
 7.693
8.728
9.815
 OE1
OE1
O
 C12
O13
O
GLN B:130 B:128 122.0 0.678 T 55.0 47.3 NA NA NA
GLN C:130 C:128 126.0 0.7 T 47.2 46.1 NA NA NA
4k19 1 P80188 98.88 3e-132 X-RAY
 2013-07-31 GLN A:130 A:128 113.0 0.628 T 56.9 31.4 113.0 0.628 0.0 CL
1OD
 8.165
6.807
 CB
OE1
 CL
O20
GLN B:130 B:128 70.0 NA T 50.5 45.7 NA NA NA
GLN C:130 C:128 157.0 0.872 T 47.4 47.0 NA NA NA
4zfx 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 106.0 0.589 T 57.1 36.8 106.0 0.589 0.0 EB4
 7.640
 OE1
 C30
GLN B:130 B:128 117.0 0.65 T 59.8 35.5 117.0 0.65 0.0
GLN C:130 C:128 128.0 0.711 T 59.3 35.3 128.0 0.711 0.0 EB4
 8.460
 CG
 C29
4zhc 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 100.0 0.556 T 51.2 37.0 100.0 0.556 0.0 TC2
HOH
 9.438
3.204
 CG
N
 C10
O
GLN B:130 B:128 121.0 0.672 T 52.3 38.4 NA NA NA
GLN C:130 C:128 124.0 0.689 T 52.4 37.7 NA NA NA
4zhd 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 104.0 0.578 T 45.7 44.3 104.0 0.578 0.0 4OZ
HOH
 7.989
9.823
 OE1
O
 C15
O
GLN B:130 B:128 149.0 0.828 T 48.9 44.1 NA NA NA
GLN C:130 C:128 128.0 0.711 T 49.3 43.1 NA NA NA
4zhf 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 108.0 0.6 T 50.3 36.5 108.0 0.6 0.0 4OL
 7.852
 OE1
 C25
GLN B:130 B:128 125.0 0.694 T 49.9 38.3 NA NA NA
GLN C:130 C:128 126.0 0.7 T 49.7 39.8 NA NA NA
GLN D:130 D:128 122.0 0.678 T 50.3 39.1 NA NA NA
GLN E:130 E:128 107.0 0.594 T 51.0 37.9 NA NA NA
GLN F:130 F:128 109.0 0.606 T 50.6 37.8 NA NA NA
4zhg 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 103.0 0.572 T 53.4 34.9 103.0 0.572 0.0 4OL
HOH
 8.214
9.809
 OE1
O
 C25
O
GLN B:130 B:128 123.0 0.683 T 52.0 37.0 NA NA NA
GLN C:130 C:128 124.0 0.689 T 51.7 39.1 NA NA NA
GLN D:130 D:128 122.0 0.678 T 52.5 37.2 NA NA NA
GLN E:130 E:128 107.0 0.594 T 57.5 35.1 NA NA NA
GLN F:130 F:128 109.0 0.606 T 57.2 36.3 NA NA NA
4zhh 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLN A:130 A:128 101.0 0.561 T 49.1 34.3 101.0 0.561 0.0 4OL
HOH
 7.772
3.055
 OE1
N
 C24
O
GLN B:130 B:128 120.0 0.667 T 47.0 40.2 NA NA NA
GLN C:130 C:128 119.0 0.661 T 47.6 39.6 NA NA NA
GLN D:130 D:128 119.0 0.661 T 46.2 39.2 NA NA NA
GLN E:130 E:128 105.0 0.583 T 48.9 35.9 NA NA NA
GLN F:130 F:128 106.0 0.589 T 52.3 37.4 NA NA NA
5khp 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLN A:130 A:128 109.0 0.606 T 44.1 44.9 109.0 0.606 0.0 7K9
SO4
 8.942
6.624
 OE1
NE2
 N32
O1
GLN B:130 B:128 106.0 0.589 T 47.3 42.0 NA NA NA
GLN C:130 C:128 135.0 0.75 T 56.6 37.7 NA NA NA
5kic 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLN A:130 A:128 49.0 NA T 51.3 39.0 49.0 NA NA 4OL
 8.659
 N
 O49
GLN B:130 B:128 52.0 NA T 51.1 39.9 NA NA NA
GLN C:130 C:128 66.0 NA T 48.3 41.1 NA NA NA
5kid 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLN A:130 A:128 122.0 0.678 T 51.6 37.0 122.0 0.678 0.0
GLN B:130 B:128 125.0 0.694 T 52.9 33.8 NA NA NA
GLN C:130 C:128 129.0 0.717 T 51.9 35.0 NA NA NA
3tzs 1 P80188 98.88 4e-132 X-RAY
 2011-10-12 GLN A:129 A:128 110.0 0.611 T 47.8 44.3 110.0 0.611 0.0 HOH
 3.150
 N
 O
GLN B:129 B:128 139.0 0.772 T 49.7 43.1 NA NA NA
GLN C:129 C:128 146.0 0.811 T 42.3 44.9 NA NA NA
1x71 1 P80188 99.44 5e-132 X-RAY
 2005-01-18 GLN A:128 A:128 108.0 0.6 T 46.3 43.7 108.0 0.6 0.0 HOH
 2.869
 N
 O
GLN B:128 B:128 109.0 0.606 T 62.8 36.3 NA NA NA
GLN C:128 C:128 105.0 0.583 T 50.9 44.8 NA NA NA
1x89 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 GLN A:128 A:128 97.0 0.539 T 49.3 45.6 97.0 0.539 0.0 CM1
 9.006
 NE2
 C42
GLN B:128 B:128 114.0 0.633 T 59.5 31.3 NA NA NA
GLN C:128 C:128 130.0 0.722 T 51.0 46.3 NA NA NA
1x8u 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 GLN A:128 A:128 92.0 0.511 T 47.8 45.2 92.0 0.511 0.0 CM2
 7.501
 NE2
 C39
GLN B:128 B:128 136.0 0.756 T 58.1 46.4 NA NA NA
GLN C:128 C:128 127.0 0.706 T 50.0 40.2 NA NA NA
3fw4 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 GLN A:128 A:128 116.0 0.644 T 53.7 43.1 116.0 0.644 0.0 CL
CL
HOH
 6.860
8.872
2.765
 OE1
OE1
NE2
 CL
CL
O
GLN B:128 B:128 76.0 NA S -91.4 105.5 NA NA NA
GLN C:128 C:128 118.0 0.656 T 51.0 40.2 NA NA NA
3fw5 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 GLN A:128 A:128 116.0 0.644 T 53.7 39.7 116.0 0.644 0.0 HOH
 3.289
 N
 O
GLN B:128 B:128 65.0 NA T 57.8 43.2 NA NA NA
GLN C:128 C:128 125.0 0.694 T 52.3 43.5 NA NA NA
3k3l 1 P80188 99.44 5e-132 X-RAY
 2010-08-18 GLN A:128 A:128 95.0 0.528 T 48.9 40.0 95.0 0.528 0.0 DBS
DBH
HOH
 8.330
8.046
3.297
 OE1
OE1
N
 O13
C15
O
GLN B:128 B:128 81.0 NA S 61.9 48.7 NA NA NA
GLN C:128 C:128 127.0 0.706 T 53.3 44.3 NA NA NA
3pec 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 GLN A:128 A:128 96.0 0.533 T 50.7 42.4 96.0 0.533 0.0 HOH
 3.135
 N
 O
GLN B:128 B:128 151.0 0.839 T 51.9 53.5 NA NA NA
GLN C:128 C:128 121.0 0.672 T 53.2 39.7 NA NA NA
3ped 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 GLN A:128 A:128 95.0 NA T 49.6 41.5 95.0 NA NA ZYF
HOH
 9.031
3.274
 CG
N
 C41
O
GLN B:128 B:128 111.0 NA T 46.1 52.0 NA NA NA
GLN C:128 C:128 101.0 NA T 45.6 45.6 NA NA NA
3tf6 1 P80188 98.88 5e-132 X-RAY
 2011-09-07 GLN A:129 A:128 102.0 0.567 T 53.5 39.5 102.0 0.567 0.0 HOH
 3.122
 N
 O
GLN B:129 B:128 116.0 0.644 T 54.1 39.5 NA NA NA
GLN C:129 C:128 128.0 0.711 T 52.6 39.3 NA NA NA
6o5d 1 P80188 99.43 7e-129 X-RAY
 2019-09-11 GLN A:124 A:128 118.0 0.656 T 46.5 44.3 118.0 0.656 0.0 HOH
 3.225
 N
 O
GLN B:124 B:128 127.0 0.706 T 45.6 44.9 NA NA NA
GLN C:124 C:128 124.0 0.689 T 46.4 45.8 NA NA NA
5mhh 1 P80188 96.63 1e-127 X-RAY
 2017-10-11 GLN A:128 A:128 147.0 0.817 T 54.3 39.7 147.0 0.817 0.0
6qmu 1 P80188 96.63 1e-127 X-RAY
 2019-08-28 GLN A:128 A:128 150.0 0.833 T 41.0 48.6 150.0 0.833 0.0 HOH
 8.842
 N
 O
GLN B:128 B:128 150.0 0.833 T 40.0 51.5 NA NA NA
3t1d 1 P80188 97.78 1e-120 X-RAY
 2011-08-17 GLN A:148 A:128 122.0 0.678 T 42.2 48.0 122.0 0.678 0.0 TD1
HOH
 7.206
3.292
 CG
N
 N27
O
GLN B:148 B:128 119.0 0.661 T 49.1 41.5 NA NA NA
GLN C:148 C:128 145.0 0.806 T 51.7 45.5 NA NA NA
3dsz 1 ? 91.57 4e-120 X-RAY
 2009-05-19 GLN A:128 A:128 152.0 0.844 T 48.9 50.0 152.0 0.844 0.0 HOH
 2.974
 OE1
 O
GLN B:128 B:128 128.0 0.711 T 50.1 42.8 NA NA NA
3dtq 1 P80188 91.57 4e-120 X-RAY
 2009-05-12 GLN A:128 A:128 126.0 0.7 T 54.9 43.2 126.0 0.7 0.0 HOH
 2.603
 O
 O
GLN B:128 B:128 98.0 0.544 T 49.9 36.9 NA NA NA
GLN C:128 C:128 114.0 0.633 T 53.6 34.1 NA NA NA
5n47 1 P80188 90.45 6e-118 X-RAY
 2018-02-14 GLN A:128 A:128 135.0 0.75 T 48.6 34.9 50.0 0.278 0.472 B:P02751:0.472
GLN C:128 C:128 142.0 0.789 T 48.7 42.5 NA NA NA
GLN E:128 E:128 154.0 0.856 T 62.0 35.9 NA NA NA
1qqs 1 P80188 97.7 4e-116 X-RAY
 2000-04-21 GLN A:125 A:128 147.0 0.817 T 37.1 38.1 145.0 0.806 0.011 A:P80188:0.011
 NAG
NAG
MAN
HOH
 3.394
2.797
4.896
3.836
 O
O
CG
N
 C6
N2
O2
O
5jr8 1 P80188 94.38 3e-115 X-RAY
 2016-09-28 GLN A:128 A:128 162.0 0.9 T 50.8 40.2 162.0 0.9 0.0 HOH
 8.804
 N
 O
GLN B:128 B:128 162.0 0.9 T 57.7 24.5 NA NA NA
4mvl 1 P80188 89.33 1e-114 X-RAY
 2015-08-12 GLN A:128 A:128 179.0 0.994 S 66.1 71.2 179.0 0.994 0.0 HOH
 6.708
 O
 O
GLN B:128 B:128 201.0 1.0 S 61.2 -86.6 NA NA NA
GLN C:128 C:128 184.0 1.0 S -47.8 -72.5 NA NA NA
GLN D:128 D:128 164.0 0.911 S -68.9 -95.5 NA NA NA
4mvi 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 GLN A:128 A:128 126.0 0.7 T 54.5 43.1 124.0 0.689 0.011 B:P05067:0.011
 HOH
 5.781
 O
 O
4mvk 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 GLN A:128 A:128 146.0 0.811 T 45.2 45.6 146.0 0.811 0.0 HOH
 2.666
 O
 O
5n48 1 P80188 88.2 1e-113 X-RAY
 2018-02-14 GLN A:128 A:128 160.0 0.889 T 54.2 -105.1 149.0 0.828 0.061 B:P02751:0.061
 HOH
 3.144
 O
 O
GLN C:128 C:128 114.0 0.633 T 50.8 -92.1 NA NA NA
4gh7 1 P80188 88.2 1e-113 X-RAY
 2012-12-26 GLN A:128 A:128 129.0 0.717 T 48.5 43.3 103.0 0.572 0.145 B:P02751:0.144
 HOH
 4.848
 NE2
 O
GLN C:128 C:128 114.0 0.633 T 52.9 51.8 NA NA NA
6s8v 1 P80188 88.2 9e-113 X-RAY
 2020-03-04 GLN A:128 A:128 129.0 0.717 T 48.9 -121.8 114.0 0.633 0.084 B:P08195:0.083
 HOH
 2.668
 NE2
 O
GLN C:128 C:128 127.0 0.706 T 51.9 -123.6 NA NA NA
6sua 1 P80188 88.76 2e-112 X-RAY
 2020-06-17 GLN A:128 A:128 158.0 0.878 S 57.1 66.7 25.0 0.139 0.739 B:P10852:0.739
 SO4
HOH
 6.667
2.655
 N
O
 O2
O
GLN C:128 C:128 156.0 0.867 S 57.5 67.9 NA NA NA
4iaw 1 P80188 87.08 3e-112 X-RAY
 2013-06-19 GLN A:128 A:128 113.0 0.628 T 37.3 56.2 113.0 0.628 0.0 HOH
 3.180
 N
 O
GLN B:128 B:128 117.0 0.65 T 55.2 40.9 NA NA NA
GLN C:128 C:128 115.0 0.639 T 49.3 55.6 NA NA NA
6z2c 1 P80188 88.2 4e-111 X-RAY
 2021-05-26 GLN A:128 A:128 167.0 0.928 T 50.8 48.1 167.0 0.928 0.0 HOH
 2.894
 N
 O
GLN B:128 B:128 168.0 0.933 T 49.7 47.4 NA NA NA
GLN C:128 C:128 174.0 0.967 T 50.4 47.9 NA NA NA
6z6z 1 P80188 86.52 3e-110 X-RAY
 2021-06-09 GLN A:129 A:128 190.0 1.0 T -54.8 -36.8 190.0 1.0 0.0 HOH
 4.329
 O
 O
4qae 2 P80188 85.39 3e-109 X-RAY
 2015-05-06 GLN G:128 A:128 143.0 0.794 T 49.6 47.3 63.0 0.35 0.444 A:P81172:0.444
 HOH
 2.709
 O
 O
GLN H:128 B:128 145.0 0.806 T 47.6 49.3 NA NA NA
GLN I:128 C:128 140.0 0.778 T 50.3 47.7 NA NA NA
GLN J:128 D:128 142.0 0.789 T 47.0 44.5 NA NA NA
GLN K:128 E:128 135.0 0.75 T 48.3 45.8 NA NA NA
GLN L:128 F:128 144.0 0.8 T 47.1 46.6 NA NA NA
3bx7 2 ? 83.15 4e-108 X-RAY
 2009-01-20 ASP B:128 A:128 87.0 0.58 T -47.0 -55.2 67.0 0.447 0.133 A:P16410:0.133
 HOH
 4.910
 N
 O
3bx8 1 ? 83.15 4e-108 X-RAY
 2009-01-20 ASP A:128 NA:NA DO NA DO DO DO NA NA NA
ASP B:128 B:128 84.0 0.56 360.0 151.2 NA NA NA
ASP C:128 NA:NA DO NA DO DO DO NA NA NA
ASP D:128 D:128 60.0 0.4 S -149.0 148.4 NA NA NA
ASP E:128 NA:NA DO NA DO DO DO NA NA NA
ASP F:128 NA:NA DO NA DO DO DO NA NA NA
ASP G:128 NA:NA DO NA DO DO DO NA NA NA
ASP H:128 NA:NA DO NA DO DO DO NA NA NA
5nkn 1 P80188 86.21 2e-106 X-RAY
 2018-04-04 GLN A:124 A:128 175.0 0.972 T -40.5 -54.3 175.0 0.972 0.0
6gqz 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 GLN A:124 A:128 161.0 0.894 T 47.6 39.1 161.0 0.894 0.0 HOH
 3.082
 NE2
 O
GLN B:124 B:128 147.0 0.817 T 48.7 37.9 NA NA NA
6gr0 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 GLN A:124 A:128 168.0 0.933 T 45.5 44.7 168.0 0.933 0.0 HOH
 6.323
 N
 O
GLN B:124 B:128 157.0 0.872 T 50.2 39.2 NA NA NA
GLN C:124 C:128 163.0 0.906 T 46.2 46.3 NA NA NA
4iax 1 P80188 81.46 3e-103 X-RAY
 2013-06-19 GLN A:128 A:128 108.0 0.6 T 53.2 30.8 108.0 0.6 0.0 HOH
 3.250
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p80188-f1 1 P80188 100.0 1e-149 GLN A:148 A:148 145.0 0.806 T 50.8 45.8