Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 130914277 . A C CCDS6892.1:NM_005564.3:c.448Agg>Cgg_NP_005555.2:p.150R>R Homo sapiens lipocalin 2 (LCN2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3hwe 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 ARG A:150 A:130 52.0 NA E -103.7 125.8 52.0 NA NA RKS
RKS
HOH
 5.487
9.060
4.293
 NE
NE
N
 C24
O8
O
ARG B:150 B:130 76.0 0.338 -135.2 108.8 NA NA NA
ARG C:150 C:130 61.0 0.271 E -121.2 131.1 NA NA NA
3hwf 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 ARG A:150 A:130 106.0 0.471 E -89.8 147.2 106.0 0.471 0.0 TC2
NA
HOH
 7.998
5.124
8.215
 NH2
N
CD
 C18
NA
O
ARG B:150 B:130 117.0 0.52 E -105.2 125.8 NA NA NA
ARG C:150 C:130 80.0 0.356 E -112.1 128.8 NA NA NA
3hwg 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 ARG A:150 A:130 39.0 NA E -96.9 134.8 39.0 NA NA QED
NA
HOH
 8.388
5.913
3.160
 O
CD
CD
 C28
NA
O
ARG B:150 B:130 86.0 0.382 E -107.1 131.1 NA NA NA
ARG C:150 C:130 46.0 0.204 E -112.6 131.3 NA NA NA
3u0d 1 P80188 99.49 4e-148 X-RAY
 2011-10-12 ARG A:150 A:130 61.0 0.271 E -101.4 143.4 61.0 0.271 0.0 DBH
DBH
HOH
 9.280
8.451
5.188
 O
O
N
 O17
C12
O
ARG B:150 B:130 53.0 0.236 E -101.4 142.0 NA NA NA
ARG C:150 C:130 79.0 0.351 E -86.1 147.6 NA NA NA
ARG D:150 D:130 19.0 NA E -107.0 132.0 NA NA NA
3cbc 1 P80188 98.99 1e-147 X-RAY
 2008-09-09 ARG A:150 A:130 87.0 0.387 E -101.4 131.9 NA NA NA
ARG B:150 B:130 40.0 NA E -100.0 130.2 40.0 NA NA DBS
HOH
 8.004
5.320
 O
C
 C10
O
ARG C:150 C:130 47.0 0.209 E -107.7 131.3 NA NA NA
3cmp 1 P80188 98.99 3e-147 X-RAY
 2009-05-12 ARG A:150 A:130 56.0 NA E -90.9 126.9 56.0 NA NA EB4
HOH
 6.412
5.047
 O
N
 O11
O
ARG B:150 B:130 92.0 NA E -120.5 122.6 NA NA NA
ARG C:150 C:130 54.0 0.24 -101.6 123.9 NA NA NA
3i0a 1 P80188 98.99 3e-147 X-RAY
 2010-06-09 ARG A:150 A:130 55.0 NA E -97.6 131.4 55.0 NA NA 3ET
2DS
HOH
 7.736
9.449
6.668
 NE
O
C
 O14
C22
O
ARG B:150 B:130 149.0 0.662 -100.8 130.8 NA NA NA
ARG C:150 C:130 41.0 0.182 E -102.4 127.7 NA NA NA
3hwd 1 P80188 98.48 1e-146 X-RAY
 2010-06-02 ARG A:150 A:130 84.0 0.373 E -113.7 121.7 84.0 0.373 0.0 NA
HOH
 8.785
6.648
 O
C
 NA
O
ARG B:150 B:130 23.0 NA E -115.6 123.5 NA NA NA
ARG C:150 C:130 70.0 0.311 E -115.2 119.7 NA NA NA
3by0 1 P80188 98.48 9e-146 X-RAY
 2008-09-09 ARG A:150 A:130 114.0 0.507 E -98.4 134.5 114.0 0.507 0.0 DBS
DBH
HOH
 7.563
9.844
2.828
 O
O
NH2
 O13
O6
O
ARG B:150 B:130 109.0 0.484 E -90.7 137.3 NA NA NA
ARG C:150 C:130 55.0 0.244 E -106.7 133.7 NA NA NA
1dfv 1 P80188 100.0 2e-132 X-RAY
 2000-03-06 ARG A:130 A:130 107.0 0.476 E -88.9 133.0 107.0 0.476 0.0 HOH
 5.094
 N
 O
ARG B:130 B:130 82.0 0.364 E -98.5 127.1 NA NA NA
1l6m 1 P80188 98.88 3e-132 X-RAY
 2003-03-11 ARG A:132 A:130 93.0 0.413 E -89.7 136.0 93.0 0.413 0.0 DBH
DBS
HOH
 8.881
7.145
5.264
 NH2
NH2
C
 C9
O13
O
ARG B:132 B:130 117.0 0.52 E -105.2 135.1 NA NA NA
ARG C:132 C:130 66.0 0.293 E -108.5 139.1 NA NA NA
4k19 1 P80188 98.88 3e-132 X-RAY
 2013-07-31 ARG A:132 A:130 114.0 0.507 E -84.4 139.6 114.0 0.507 0.0 CL
1OD
HOH
 2.715
8.442
7.875
 NH1
NH2
O
 CL
C17
O
ARG B:132 B:130 118.0 0.524 E -94.9 134.0 NA NA NA
ARG C:132 C:130 46.0 0.204 E -122.5 129.3 NA NA NA
4zfx 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 88.0 0.391 E -103.4 134.5 88.0 0.391 0.0 EB4
HOH
 6.938
9.563
 NH2
O
 C30
O
ARG B:132 B:130 147.0 0.653 E -103.8 135.2 147.0 0.653 0.0
ARG C:132 C:130 77.0 0.342 E -105.9 136.0 77.0 0.342 0.0 EB4
HOH
 7.846
7.216
 NE
NH2
 C29
O
4zhc 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 101.0 0.449 E -103.4 137.0 101.0 0.449 0.0 TC2
HOH
 7.491
5.013
 NH2
N
 C10
O
ARG B:132 B:130 109.0 0.484 E -104.6 137.2 NA NA NA
ARG C:132 C:130 63.0 0.28 E -105.6 136.8 NA NA NA
4zhd 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 96.0 0.427 E -101.3 139.0 96.0 0.427 0.0 4OZ
HOH
 6.064
5.198
 NH2
C
 C15
O
ARG B:132 B:130 112.0 0.498 E -104.3 137.7 NA NA NA
ARG C:132 C:130 47.0 0.209 E -103.6 137.0 NA NA NA
4zhf 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 73.0 0.324 E -98.3 137.5 73.0 0.324 0.0 4OL
HOH
 7.073
6.650
 NH2
C
 C24
O
ARG B:132 B:130 47.0 0.209 E -97.3 136.5 NA NA NA
ARG C:132 C:130 48.0 0.213 E -96.0 136.1 NA NA NA
ARG D:132 D:130 69.0 0.307 E -97.3 136.6 NA NA NA
ARG E:132 E:130 66.0 0.293 E -95.5 137.7 NA NA NA
ARG F:132 F:130 73.0 0.324 E -95.5 137.4 NA NA NA
4zhg 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 72.0 0.32 E -97.4 136.6 72.0 0.32 0.0 4OL
HOH
 7.380
5.175
 NH2
C
 C24
O
ARG B:132 B:130 46.0 0.204 E -94.3 133.2 NA NA NA
ARG C:132 C:130 48.0 0.213 E -94.6 132.0 NA NA NA
ARG D:132 D:130 67.0 0.298 E -96.1 134.1 NA NA NA
ARG E:132 E:130 68.0 0.302 E -91.7 134.9 NA NA NA
ARG F:132 F:130 73.0 0.324 E -92.5 134.2 NA NA NA
4zhh 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 ARG A:132 A:130 71.0 0.316 E -95.8 136.6 71.0 0.316 0.0 4OL
HOH
 6.856
4.955
 NH2
N
 C24
O
ARG B:132 B:130 42.0 0.187 E -95.2 135.9 NA NA NA
ARG C:132 C:130 43.0 0.191 E -94.4 134.1 NA NA NA
ARG D:132 D:130 65.0 0.289 E -98.8 135.9 NA NA NA
ARG E:132 E:130 60.0 0.267 E -91.9 138.4 NA NA NA
ARG F:132 F:130 69.0 0.307 E -93.8 134.2 NA NA NA
5khp 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 ARG A:132 A:130 118.0 0.524 E -108.3 136.8 118.0 0.524 0.0 7K9
HOH
 8.376
7.926
 O
O
 C42
O
ARG B:132 B:130 145.0 0.644 E -106.8 137.7 NA NA NA
ARG C:132 C:130 76.0 0.338 E -100.7 138.0 NA NA NA
5kic 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 ARG A:132 A:130 114.0 0.507 E -100.7 136.8 114.0 0.507 0.0 4OL
HOH
 6.815
9.687
 NE
O
 C25
O
ARG B:132 B:130 89.0 0.396 E -99.7 137.1 NA NA NA
ARG C:132 C:130 49.0 0.218 E -99.5 135.4 NA NA NA
5kid 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 ARG A:132 A:130 77.0 0.342 E -108.8 134.9 77.0 0.342 0.0 7K9
HOH
 8.168
8.135
 O
NH1
 C24
O
ARG B:132 B:130 76.0 0.338 E -108.7 135.2 NA NA NA
ARG C:132 C:130 59.0 0.262 E -108.6 134.2 NA NA NA
3tzs 1 P80188 98.88 4e-132 X-RAY
 2011-10-12 ARG A:131 A:130 97.0 0.431 E -105.9 143.5 97.0 0.431 0.0 PHU
HOH
 8.269
4.936
 O
N
 C3
O
ARG B:131 B:130 23.0 NA E -95.8 139.6 NA NA NA
ARG C:131 C:130 75.0 0.333 E -103.9 141.2 NA NA NA
1x71 1 P80188 99.44 5e-132 X-RAY
 2005-01-18 ARG A:130 A:130 85.0 0.378 E -103.2 139.2 85.0 0.378 0.0 DB1
HOH
 8.159
4.909
 O
N
 C13
O
ARG B:130 B:130 90.0 0.4 E -104.2 142.5 NA NA NA
ARG C:130 C:130 89.0 0.396 E -107.4 143.6 NA NA NA
1x89 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 ARG A:130 A:130 101.0 0.449 E -95.4 141.6 101.0 0.449 0.0 CM1
HOH
 8.167
6.516
 O
C
 C6
O
ARG B:130 B:130 95.0 0.422 E -98.6 142.7 NA NA NA
ARG C:130 C:130 77.0 0.342 E -101.5 135.4 NA NA NA
1x8u 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 ARG A:130 A:130 93.0 0.413 E -100.2 138.6 93.0 0.413 0.0 CM2
HOH
 8.155
6.693
 O
C
 C6
O
ARG B:130 B:130 116.0 0.516 E -96.8 147.2 NA NA NA
ARG C:130 C:130 82.0 0.364 E -98.7 134.8 NA NA NA
3fw4 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 ARG A:130 A:130 60.0 NA E -108.5 133.0 60.0 NA NA CAQ
CL
CL
HOH
 8.138
8.941
7.284
4.755
 O
O
NE
N
 C6
CL
CL
O
ARG B:130 B:130 121.0 NA -161.1 134.3 NA NA NA
ARG C:130 C:130 78.0 0.347 E -112.1 133.9 NA NA NA
3fw5 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 ARG A:130 A:130 56.0 NA E -105.7 131.2 56.0 NA NA MCT
HOH
 8.203
4.821
 O
N
 C5
O
ARG B:130 B:130 123.0 NA E -120.4 119.7 NA NA NA
ARG C:130 C:130 53.0 0.236 E -110.2 131.2 NA NA NA
3k3l 1 P80188 99.44 5e-132 X-RAY
 2010-08-18 ARG A:130 A:130 96.0 0.427 E -95.7 127.3 96.0 0.427 0.0 DBS
DBH
HOH
 6.702
8.782
4.870
 NH2
NH2
NE
 O13
O17
O
ARG B:130 B:130 55.0 NA S -156.0 133.6 NA NA NA
ARG C:130 C:130 48.0 0.213 E -109.4 130.0 NA NA NA
3pec 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 ARG A:130 A:130 87.0 0.387 E -105.6 131.5 87.0 0.387 0.0 HOH
 4.586
 N
 O
ARG B:130 B:130 127.0 0.564 E -88.8 136.1 NA NA NA
ARG C:130 C:130 51.0 0.227 E -108.7 132.0 NA NA NA
3ped 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 ARG A:130 A:130 56.0 NA E -103.1 137.8 56.0 NA NA ZYF
HOH
 8.149
4.696
 O
N
 C6
O
ARG B:130 B:130 80.0 0.356 E -102.0 141.4 NA NA NA
ARG C:130 C:130 141.0 0.627 E -98.8 138.4 NA NA NA
3tf6 1 P80188 98.88 5e-132 X-RAY
 2011-09-07 ARG A:131 A:130 77.0 0.342 E -103.6 141.1 77.0 0.342 0.0 DBH
HOH
 8.162
4.887
 O
N
 C15
O
ARG B:131 B:130 102.0 0.453 E -102.1 140.4 NA NA NA
ARG C:131 C:130 71.0 0.316 E -102.1 139.2 NA NA NA
6o5d 1 P80188 99.43 7e-129 X-RAY
 2019-09-11 ARG A:126 A:130 119.0 0.529 E -101.1 134.9 119.0 0.529 0.0 HOH
 4.896
 N
 O
ARG B:126 B:130 122.0 0.542 E -100.9 134.4 NA NA NA
ARG C:126 C:130 77.0 0.342 E -101.2 134.4 NA NA NA
5mhh 1 P80188 96.63 1e-127 X-RAY
 2017-10-11 ARG A:130 A:130 92.0 0.409 E -134.4 139.4 92.0 0.409 0.0 HOH
 8.069
 NH2
 O
6qmu 1 P80188 96.63 1e-127 X-RAY
 2019-08-28 ARG A:130 A:130 96.0 0.427 E -109.0 143.8 96.0 0.427 0.0 HOH
 7.516
 NH2
 O
ARG B:130 B:130 110.0 0.489 E -109.3 142.6 NA NA NA
3t1d 1 P80188 97.78 1e-120 X-RAY
 2011-08-17 ARG A:150 A:130 53.0 0.236 E -102.5 136.7 53.0 0.236 0.0 TD1
HOH
 6.792
2.926
 NE
CD
 N27
O
ARG B:150 B:130 99.0 0.44 E -103.6 140.6 NA NA NA
ARG C:150 C:130 81.0 0.36 E -98.3 138.8 NA NA NA
3dsz 1 ? 91.57 4e-120 X-RAY
 2009-05-19 ARG A:130 A:130 157.0 0.698 E -121.2 138.3 157.0 0.698 0.0 HOH
 2.949
 NE
 O
ARG B:130 B:130 164.0 0.729 E -115.8 142.0 NA NA NA
3dtq 1 P80188 91.57 4e-120 X-RAY
 2009-05-12 ARG A:130 A:130 71.0 0.316 E -101.7 130.4 71.0 0.316 0.0 HOH
 2.238
 O
 O
ARG B:130 B:130 104.0 0.462 E -95.7 134.3 NA NA NA
ARG C:130 C:130 60.0 0.267 E -112.3 137.9 NA NA NA
5n47 1 P80188 90.45 6e-118 X-RAY
 2018-02-14 ARG A:130 A:130 40.0 0.178 E -121.6 128.0 37.0 0.164 0.014 B:P02751:0.013
ARG C:130 C:130 37.0 0.164 E -120.5 134.8 NA NA NA
ARG E:130 E:130 115.0 0.511 E -135.7 116.2 NA NA NA
1qqs 1 P80188 97.7 4e-116 X-RAY
 2000-04-21 ARG A:127 A:130 102.0 0.453 B -114.6 137.3 73.0 0.324 0.129 A:P80188:0.129
 NAG
NAG
MAN
HOH
 6.550
3.135
4.524
3.959
 CG
CG
NH2
NH2
 O4
O3
O6
O
5jr8 1 P80188 94.38 3e-115 X-RAY
 2016-09-28 GLN A:130 A:130 94.0 0.522 E -126.0 143.7 94.0 0.522 0.0 HOH
 9.549
 O
 O
GLN B:130 B:130 72.0 0.4 E -131.1 146.7 NA NA NA
4mvl 1 P80188 89.33 1e-114 X-RAY
 2015-08-12 ARG A:130 A:130 164.0 0.729 S -93.8 126.0 164.0 0.729 0.0 HOH
 3.781
 CA
 O
ARG B:130 B:130 168.0 0.747 -93.4 117.7 NA NA NA
ARG C:130 C:130 144.0 0.64 -68.3 135.9 NA NA NA
ARG D:130 D:130 141.0 0.627 -79.2 143.3 NA NA NA
4mvi 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 ARG A:130 A:130 144.0 0.64 E -101.6 135.3 144.0 0.64 0.0 HOH
 2.894
 O
 O
4mvk 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 ARG A:130 A:130 173.0 0.769 E -95.4 132.6 173.0 0.769 0.0 HOH
 2.876
 O
 O
5n48 1 P80188 88.2 1e-113 X-RAY
 2018-02-14 ARG A:130 A:130 88.0 0.391 E -93.1 126.5 11.0 0.049 0.342 B:P02751:0.342
 HOH
 2.967
 NH2
 O
ARG C:130 C:130 92.0 0.409 E -111.9 117.9 NA NA NA
4gh7 1 P80188 88.2 1e-113 X-RAY
 2012-12-26 ARG A:130 A:130 106.0 0.471 E -111.9 127.1 87.0 0.387 0.084 B:P02751:0.084
 HOH
 3.664
 CA
 O
ARG C:130 C:130 110.0 0.489 E -108.9 124.3 NA NA NA
6s8v 1 P80188 88.2 9e-113 X-RAY
 2020-03-04 ARG A:130 A:130 141.0 0.627 E -99.9 131.1 128.0 0.569 0.058 B:P08195:0.058
 HOH
 2.902
 O
 O
ARG C:130 C:130 129.0 0.573 E -106.5 139.1 NA NA NA
6sua 1 P80188 88.76 2e-112 X-RAY
 2020-06-17 ARG A:130 A:130 78.0 0.347 -130.7 152.5 20.0 0.089 0.258 B:P10852:0.258
 SO4
SO4
HOH
 9.411
9.155
3.279
 C
N
NH1
 O4
O2
O
ARG C:130 C:130 82.0 0.364 -130.2 152.0 NA NA NA
4iaw 1 P80188 87.08 3e-112 X-RAY
 2013-06-19 ARG A:130 A:130 64.0 0.284 E -105.6 134.4 64.0 0.284 0.0 HOH
 5.079
 N
 O
ARG B:130 B:130 61.0 0.271 E -83.4 143.6 NA NA NA
ARG C:130 C:130 141.0 0.627 E -98.6 153.7 NA NA NA
6z2c 1 P80188 88.2 4e-111 X-RAY
 2021-05-26 ARG A:130 A:130 120.0 0.533 E -131.7 149.7 120.0 0.533 0.0 HOH
 3.202
 CG
 O
ARG B:130 B:130 132.0 0.587 E -131.9 146.4 NA NA NA
ARG C:130 C:130 116.0 0.516 E -131.6 145.6 NA NA NA
6z6z 1 P80188 86.52 3e-110 X-RAY
 2021-06-09 ARG A:131 A:130 78.0 0.347 -103.8 141.3 78.0 0.347 0.0 CA
HOH
 7.951
2.747
 NH1
O
 CA
O
4qae 2 P80188 85.39 3e-109 X-RAY
 2015-05-06 ARG G:130 A:130 88.0 0.391 E -145.5 163.0 78.0 0.347 0.044 A:P81172:0.044
 HOH
 3.067
 NH1
 O
ARG H:130 B:130 85.0 0.378 E -130.6 172.0 NA NA NA
ARG I:130 C:130 84.0 0.373 E -128.5 148.8 NA NA NA
ARG J:130 D:130 77.0 0.342 E -135.5 170.7 NA NA NA
ARG K:130 E:130 81.0 0.36 E -129.1 167.6 NA NA NA
ARG L:130 F:130 78.0 0.347 E -136.3 167.9 NA NA NA
3bx7 2 ? 83.15 4e-108 X-RAY
 2009-01-20 ALA B:130 A:130 37.0 0.322 E -169.9 155.4 36.0 0.313 0.009 A:P16410:0.009
 HOH
 3.643
 CB
 O
3bx8 1 ? 83.15 4e-108 X-RAY
 2009-01-20 ALA A:130 A:130 106.0 0.922 360.0 119.7 106.0 0.922 0.0 HOH
 7.091
 C
 O
ALA B:130 B:130 60.0 0.522 T -90.6 15.4 NA NA NA
ALA C:130 C:130 106.0 0.922 360.0 134.3 NA NA NA
ALA D:130 D:130 54.0 0.47 T -100.1 19.8 NA NA NA
ALA E:130 NA:NA DO NA DO DO DO NA NA NA
ALA F:130 NA:NA DO NA DO DO DO NA NA NA
ALA G:130 NA:NA DO NA DO DO DO NA NA NA
ALA H:130 NA:NA DO NA DO DO DO NA NA NA
5nkn 1 P80188 86.21 2e-106 X-RAY
 2018-04-04 ARG A:126 A:130 92.0 0.409 -131.9 119.2 92.0 0.409 0.0 LOC
HOH
 3.913
7.354
 NH2
NH2
 O5
O
6gqz 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 ARG A:126 A:130 146.0 0.649 E -139.9 150.6 146.0 0.649 0.0 HOH
 3.148
 NH2
 O
ARG B:126 B:130 184.0 0.818 E -118.7 129.9 NA NA NA
6gr0 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 ARG A:126 A:130 139.0 0.618 E -99.5 120.4 139.0 0.618 0.0 F8W
HOH
 8.240
2.831
 NH1
O
 OAX
O
ARG B:126 B:130 170.0 0.756 E -99.0 122.7 NA NA NA
ARG C:126 C:130 200.0 0.889 E -98.8 118.4 NA NA NA
4iax 1 P80188 81.46 3e-103 X-RAY
 2013-06-19 ARG A:130 A:130 130.0 0.578 E -104.3 140.0 130.0 0.578 0.0 HOH
 4.917
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p80188-f1 1 P80188 100.0 1e-149 ARG A:150 A:150 99.0 0.44 E -110.8 135.1