Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 130914304 . G A CCDS6892.1:NM_005564.3:c.475Ggg>Agg_NP_005555.2:p.159G>R Homo sapiens lipocalin 2 (LCN2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3hwe 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLY A:159 A:139 0.0 0.0 E -125.3 136.6 0.0 0.0 0.0 HOH
 8.060
 N
 O
GLY B:159 B:139 0.0 0.0 E -130.7 143.8 NA NA NA
GLY C:159 C:139 0.0 0.0 E -125.9 134.6 NA NA NA
3hwf 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLY A:159 A:139 0.0 0.0 E -114.6 134.8 0.0 0.0 0.0 SO4
HOH
 8.679
9.158
 N
O
 O1
O
GLY B:159 B:139 2.0 0.027 E -125.9 137.4 NA NA NA
GLY C:159 C:139 3.0 0.04 E -124.7 134.9 NA NA NA
3hwg 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 GLY A:159 A:139 0.0 0.0 E -122.6 138.3 0.0 0.0 0.0 GOL
SO4
HOH
 8.933
9.084
6.582
 O
N
C
 O3
O1
O
GLY B:159 B:139 0.0 0.0 E -140.4 140.0 NA NA NA
GLY C:159 C:139 0.0 0.0 E -129.1 143.5 NA NA NA
3u0d 1 P80188 99.49 4e-148 X-RAY
 2011-10-12 GLY A:159 A:139 0.0 0.0 E -141.4 156.8 0.0 0.0 0.0 HOH
 3.820
 CA
 O
GLY B:159 B:139 0.0 0.0 E -119.9 149.2 NA NA NA
GLY C:159 C:139 0.0 0.0 E -115.2 136.6 NA NA NA
GLY D:159 D:139 0.0 0.0 E -131.3 155.9 NA NA NA
3cbc 1 P80188 98.99 1e-147 X-RAY
 2008-09-09 GLY A:159 A:139 0.0 0.0 E -131.7 139.0 NA NA NA
GLY B:159 B:139 0.0 0.0 E -141.5 137.6 0.0 0.0 0.0 HOH
 3.417
 C
 O
GLY C:159 C:139 0.0 0.0 E -129.4 146.1 NA NA NA
3cmp 1 P80188 98.99 3e-147 X-RAY
 2009-05-12 GLY A:159 A:139 0.0 0.0 E -127.9 140.8 0.0 0.0 0.0 SO4
HOH
 8.744
6.826
 N
C
 O1
O
GLY B:159 B:139 5.0 0.067 E -143.3 139.9 NA NA NA
GLY C:159 C:139 0.0 0.0 E -129.6 137.1 NA NA NA
3i0a 1 P80188 98.99 3e-147 X-RAY
 2010-06-09 GLY A:159 A:139 0.0 0.0 E -129.1 142.3 0.0 0.0 0.0 HOH
 8.011
 O
 O
GLY B:159 B:139 1.0 0.013 E -156.9 137.7 NA NA NA
GLY C:159 C:139 0.0 0.0 E -133.3 143.6 NA NA NA
3hwd 1 P80188 98.48 1e-146 X-RAY
 2010-06-02 GLY A:159 A:139 0.0 0.0 E -127.8 140.0 0.0 0.0 0.0 HOH
 9.311
 N
 O
GLY B:159 B:139 10.0 0.133 E -134.3 141.0 NA NA NA
GLY C:159 C:139 0.0 0.0 E -127.9 139.7 NA NA NA
3by0 1 P80188 98.48 9e-146 X-RAY
 2008-09-09 GLY A:159 A:139 0.0 0.0 E -126.5 140.1 0.0 0.0 0.0 HOH
 6.680
 C
 O
GLY B:159 B:139 0.0 0.0 E -129.3 140.8 NA NA NA
GLY C:159 C:139 0.0 0.0 E -131.3 145.4 NA NA NA
1dfv 1 P80188 100.0 2e-132 X-RAY
 2000-03-06 GLY A:139 A:139 0.0 0.0 E -130.5 138.1 0.0 0.0 0.0 HOH
 7.038
 C
 O
GLY B:139 B:139 0.0 0.0 E -133.8 145.2 NA NA NA
1l6m 1 P80188 98.88 3e-132 X-RAY
 2003-03-11 GLY A:141 A:139 0.0 0.0 E -120.4 139.1 0.0 0.0 0.0 HOH
 6.386
 C
 O
GLY B:141 B:139 4.0 0.053 E -118.5 142.0 NA NA NA
GLY C:141 C:139 7.0 0.093 E -126.4 139.3 NA NA NA
4k19 1 P80188 98.88 3e-132 X-RAY
 2013-07-31 GLY A:141 A:139 0.0 0.0 E -124.8 137.4 0.0 0.0 0.0 HOH
 8.346
 N
 O
GLY B:141 B:139 5.0 0.067 E -130.8 137.4 NA NA NA
GLY C:141 C:139 0.0 0.0 E -119.4 149.3 NA NA NA
4zfx 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -127.4 146.6 0.0 0.0 0.0 HOH
 7.639
 C
 O
GLY B:141 B:139 2.0 0.027 E -128.9 147.3 2.0 0.027 0.0
GLY C:141 C:139 0.0 0.0 E -130.6 147.6 0.0 0.0 0.0 HOH
 8.455
 N
 O
4zhc 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -124.8 148.7 0.0 0.0 0.0 ACT
HOH
 9.160
6.506
 O
C
 OXT
O
GLY B:141 B:139 0.0 0.0 E -125.4 148.7 NA NA NA
GLY C:141 C:139 0.0 0.0 E -125.5 149.6 NA NA NA
4zhd 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -127.1 147.3 0.0 0.0 0.0 HOH
 6.473
 C
 O
GLY B:141 B:139 0.0 0.0 E -128.5 146.7 NA NA NA
GLY C:141 C:139 0.0 0.0 E -128.3 149.6 NA NA NA
4zhf 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -121.5 147.6 0.0 0.0 0.0 SO4
HOH
 9.096
3.849
 N
CA
 O3
O
GLY B:141 B:139 0.0 0.0 E -122.0 146.7 NA NA NA
GLY C:141 C:139 0.0 0.0 E -121.5 147.7 NA NA NA
GLY D:141 D:139 0.0 0.0 E -121.8 146.6 NA NA NA
GLY E:141 E:139 0.0 0.0 E -120.7 147.6 NA NA NA
GLY F:141 F:139 0.0 0.0 E -119.9 149.6 NA NA NA
4zhg 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -127.5 144.8 0.0 0.0 0.0 CL
HOH
 9.776
3.542
 N
CA
 CL
O
GLY B:141 B:139 0.0 0.0 E -131.3 145.0 NA NA NA
GLY C:141 C:139 0.0 0.0 E -128.2 147.9 NA NA NA
GLY D:141 D:139 0.0 0.0 E -127.7 144.5 NA NA NA
GLY E:141 E:139 0.0 0.0 E -124.6 147.9 NA NA NA
GLY F:141 F:139 0.0 0.0 E -128.4 146.5 NA NA NA
4zhh 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 GLY A:141 A:139 0.0 0.0 E -128.7 144.6 0.0 0.0 0.0 CL
HOH
 9.816
3.707
 N
CA
 CL
O
GLY B:141 B:139 0.0 0.0 E -129.3 147.5 NA NA NA
GLY C:141 C:139 0.0 0.0 E -127.5 148.9 NA NA NA
GLY D:141 D:139 0.0 0.0 E -126.9 148.0 NA NA NA
GLY E:141 E:139 0.0 0.0 E -128.0 147.9 NA NA NA
GLY F:141 F:139 0.0 0.0 E -127.3 147.7 NA NA NA
5khp 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLY A:141 A:139 0.0 0.0 E -125.1 146.0 0.0 0.0 0.0 HOH
 8.205
 N
 O
GLY B:141 B:139 1.0 0.013 E -124.0 146.7 NA NA NA
GLY C:141 C:139 0.0 0.0 E -120.6 147.8 NA NA NA
5kic 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLY A:141 A:139 0.0 0.0 E -136.4 141.7 0.0 0.0 0.0
GLY B:141 B:139 0.0 0.0 E -136.0 144.8 NA NA NA
GLY C:141 C:139 0.0 0.0 E -138.4 142.5 NA NA NA
5kid 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 GLY A:141 A:139 0.0 0.0 E -123.9 145.8 0.0 0.0 0.0 CL
HOH
 9.833
5.308
 N
C
 CL
O
GLY B:141 B:139 0.0 0.0 E -123.3 146.8 NA NA NA
GLY C:141 C:139 0.0 0.0 E -123.8 147.3 NA NA NA
3tzs 1 P80188 98.88 4e-132 X-RAY
 2011-10-12 GLY A:140 A:139 0.0 0.0 E -128.7 147.4 0.0 0.0 0.0 CL
HOH
 9.806
5.190
 N
C
 CL
O
GLY B:140 B:139 0.0 0.0 E -131.7 144.1 NA NA NA
GLY C:140 C:139 7.0 0.093 E -132.3 140.3 NA NA NA
1x71 1 P80188 99.44 5e-132 X-RAY
 2005-01-18 GLY A:139 A:139 0.0 0.0 E -125.4 142.1 0.0 0.0 0.0 HOH
 6.599
 C
 O
GLY B:139 B:139 0.0 0.0 E -130.6 135.7 NA NA NA
GLY C:139 C:139 0.0 0.0 E -125.4 147.5 NA NA NA
1x89 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 GLY A:139 A:139 0.0 0.0 E -128.6 143.9 0.0 0.0 0.0 CM1
HOH
 9.402
6.480
 N
C
 O57
O
GLY B:139 B:139 0.0 0.0 E -135.5 144.4 NA NA NA
GLY C:139 C:139 0.0 0.0 E -128.1 141.7 NA NA NA
1x8u 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 GLY A:139 A:139 0.0 0.0 E -128.7 140.8 0.0 0.0 0.0 CM2
HOH
 9.211
6.623
 N
C
 O57
O
GLY B:139 B:139 0.0 0.0 E -124.3 142.5 NA NA NA
GLY C:139 C:139 0.0 0.0 E -128.0 141.2 NA NA NA
3fw4 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 GLY A:139 A:139 0.0 0.0 E -127.0 138.1 0.0 0.0 0.0 CL
HOH
 9.616
5.468
 N
C
 CL
O
GLY B:139 B:139 26.0 0.347 -74.3 -128.9 NA NA NA
GLY C:139 C:139 4.0 0.053 E -128.0 144.1 NA NA NA
3fw5 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 GLY A:139 A:139 0.0 0.0 E -125.2 134.8 0.0 0.0 0.0 NA
HOH
 9.138
6.580
 O
C
 NA
O
GLY B:139 B:139 6.0 0.08 E -140.1 140.3 NA NA NA
GLY C:139 C:139 0.0 0.0 E -129.1 139.4 NA NA NA
3k3l 1 P80188 99.44 5e-132 X-RAY
 2010-08-18 GLY A:139 A:139 0.0 0.0 E -120.3 133.9 0.0 0.0 0.0 GOL
NA
HOH
 9.421
9.651
8.000
 O
N
N
 O2
NA
O
GLY B:139 B:139 20.0 0.267 E -105.7 137.0 NA NA NA
GLY C:139 C:139 0.0 0.0 E -127.6 137.7 NA NA NA
3pec 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 GLY A:139 A:139 0.0 0.0 E -120.9 138.1 0.0 0.0 0.0 HOH
 5.450
 C
 O
GLY B:139 B:139 8.0 0.107 E -136.6 140.2 NA NA NA
GLY C:139 C:139 0.0 0.0 E -124.7 143.0 NA NA NA
3ped 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 GLY A:139 A:139 0.0 0.0 E -126.5 135.5 0.0 0.0 0.0 ZYF
HOH
 9.335
6.472
 N
C
 O54
O
GLY B:139 B:139 0.0 0.0 E -127.3 135.3 NA NA NA
GLY C:139 C:139 0.0 0.0 E -126.6 142.2 NA NA NA
3tf6 1 P80188 98.88 5e-132 X-RAY
 2011-09-07 GLY A:140 A:139 0.0 0.0 E -125.3 142.9 0.0 0.0 0.0 SO4
HOH
 9.180
8.068
 N
N
 O3
O
GLY B:140 B:139 0.0 0.0 E -126.8 143.6 NA NA NA
GLY C:140 C:139 0.0 0.0 E -126.9 144.0 NA NA NA
6o5d 1 P80188 99.43 7e-129 X-RAY
 2019-09-11 GLY A:135 A:139 0.0 0.0 E -122.2 141.0 0.0 0.0 0.0 HOH
 5.394
 C
 O
GLY B:135 B:139 2.0 0.027 E -122.8 141.2 NA NA NA
GLY C:135 C:139 0.0 0.0 E -122.4 142.3 NA NA NA
5mhh 1 P80188 96.63 1e-127 X-RAY
 2017-10-11 GLY A:139 A:139 0.0 0.0 E -129.6 148.2 0.0 0.0 0.0 HOH
 7.801
 O
 O
6qmu 1 P80188 96.63 1e-127 X-RAY
 2019-08-28 GLY A:139 A:139 0.0 0.0 E -125.3 150.9 0.0 0.0 0.0 HOH
 6.134
 C
 O
GLY B:139 B:139 0.0 0.0 E -124.0 151.4 NA NA NA
3t1d 1 P80188 97.78 1e-120 X-RAY
 2011-08-17 GLY A:159 A:139 0.0 0.0 E -128.9 147.8 0.0 0.0 0.0 HOH
 4.125
 CA
 O
GLY B:159 B:139 0.0 0.0 E -125.9 141.0 NA NA NA
GLY C:159 C:139 0.0 0.0 E -132.9 143.3 NA NA NA
3dsz 1 ? 91.57 4e-120 X-RAY
 2009-05-19 GLY A:139 A:139 0.0 0.0 E -130.5 147.3 0.0 0.0 0.0 LIZ
HOH
 9.467
4.849
 N
C
 O8
O
GLY B:139 B:139 0.0 0.0 E -137.1 146.4 NA NA NA
3dtq 1 P80188 91.57 4e-120 X-RAY
 2009-05-12 GLY A:139 A:139 0.0 0.0 E -126.5 146.2 0.0 0.0 0.0 HOH
 3.819
 O
 O
GLY B:139 B:139 0.0 0.0 E -139.9 148.2 NA NA NA
GLY C:139 C:139 0.0 0.0 E -132.1 146.7 NA NA NA
5n47 1 P80188 90.45 6e-118 X-RAY
 2018-02-14 GLY A:139 A:139 0.0 0.0 E -130.4 141.0 0.0 0.0 0.0
GLY C:139 C:139 6.0 0.08 E -137.7 140.6 NA NA NA
GLY E:139 E:139 3.0 0.04 E -134.9 143.1 NA NA NA
1qqs 1 P80188 97.7 4e-116 X-RAY
 2000-04-21 GLY A:136 A:139 5.0 0.067 E -130.4 144.2 5.0 0.067 0.0 DKA
HOH
 9.862
4.370
 N
O
 O2
O
5jr8 1 P80188 94.38 3e-115 X-RAY
 2016-09-28 GLY A:139 A:139 0.0 0.0 E -128.6 147.7 0.0 0.0 0.0 HOH
 4.615
 O
 O
GLY B:139 B:139 0.0 0.0 E -127.6 148.2 NA NA NA
4mvl 1 P80188 89.33 1e-114 X-RAY
 2015-08-12 GLY A:139 A:139 7.0 0.093 E -140.6 152.7 7.0 0.093 0.0 HOH
 9.475
 CA
 O
GLY B:139 B:139 2.0 0.027 E -131.9 141.7 NA NA NA
GLY C:139 C:139 5.0 0.067 E -136.1 140.5 NA NA NA
GLY D:139 D:139 4.0 0.053 E -134.4 137.4 NA NA NA
4mvi 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 GLY A:139 A:139 0.0 0.0 E -131.4 148.2 0.0 0.0 0.0 HOH
 3.633
 CA
 O
4mvk 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 GLY A:139 A:139 0.0 0.0 E -130.8 148.3 0.0 0.0 0.0 HOH
 3.611
 CA
 O
5n48 1 P80188 88.2 1e-113 X-RAY
 2018-02-14 GLY A:139 A:139 0.0 0.0 E -128.1 161.8 0.0 0.0 0.0 HOH
 4.887
 O
 O
GLY C:139 C:139 0.0 0.0 E -120.7 158.5 NA NA NA
4gh7 1 P80188 88.2 1e-113 X-RAY
 2012-12-26 GLY A:139 A:139 0.0 0.0 E -133.1 150.9 0.0 0.0 0.0 HOH
 4.878
 O
 O
GLY C:139 C:139 0.0 0.0 E -131.0 145.2 NA NA NA
6s8v 1 P80188 88.2 9e-113 X-RAY
 2020-03-04 GLY A:139 A:139 0.0 0.0 E -129.2 143.4 0.0 0.0 0.0 EDO
HOH
 8.035
4.685
 N
C
 C2
O
GLY C:139 C:139 0.0 0.0 E -119.6 150.2 NA NA NA
6sua 1 P80188 88.76 2e-112 X-RAY
 2020-06-17 GLY A:139 A:139 0.0 0.0 E -136.5 147.5 0.0 0.0 0.0 HOH
 8.371
 O
 O
GLY C:139 C:139 0.0 0.0 E -136.3 147.5 NA NA NA
4iaw 1 P80188 87.08 3e-112 X-RAY
 2013-06-19 GLY A:139 A:139 0.0 0.0 E -122.6 147.3 0.0 0.0 0.0 LIZ
HOH
 9.545
7.419
 N
CA
 O7
O
GLY B:139 B:139 0.0 0.0 E -119.7 137.0 NA NA NA
GLY C:139 C:139 0.0 0.0 E -126.3 152.2 NA NA NA
6z2c 1 P80188 88.2 4e-111 X-RAY
 2021-05-26 GLY A:139 A:139 0.0 0.0 E -125.4 151.0 0.0 0.0 0.0 HOH
 3.530
 CA
 O
GLY B:139 B:139 0.0 0.0 E -125.9 150.8 NA NA NA
GLY C:139 C:139 0.0 0.0 E -125.1 150.7 NA NA NA
6z6z 1 P80188 86.52 3e-110 X-RAY
 2021-06-09 GLY A:140 A:139 0.0 0.0 E -124.1 142.2 0.0 0.0 0.0 HOH
 4.958
 O
 O
4qae 2 P80188 85.39 3e-109 X-RAY
 2015-05-06 GLY G:139 A:139 0.0 0.0 E -125.7 149.0 0.0 0.0 0.0 HOH
 4.780
 O
 O
GLY H:139 B:139 0.0 0.0 E -129.8 144.9 NA NA NA
GLY I:139 C:139 0.0 0.0 E -124.1 148.4 NA NA NA
GLY J:139 D:139 0.0 0.0 E -120.8 147.8 NA NA NA
GLY K:139 E:139 0.0 0.0 E -122.4 151.6 NA NA NA
GLY L:139 F:139 0.0 0.0 E -126.2 148.5 NA NA NA
3bx7 2 ? 83.15 4e-108 X-RAY
 2009-01-20 GLY B:139 A:139 0.0 0.0 E -131.8 148.2 0.0 0.0 0.0 HOH
 3.643
 C
 O
3bx8 1 ? 83.15 4e-108 X-RAY
 2009-01-20 GLY A:139 A:139 0.0 0.0 E -136.5 149.0 0.0 0.0 0.0 HOH
 3.743
 CA
 O
GLY B:139 B:139 0.0 0.0 E -122.4 145.8 NA NA NA
GLY C:139 C:139 0.0 0.0 E -132.5 149.1 NA NA NA
GLY D:139 D:139 0.0 0.0 E -127.7 146.7 NA NA NA
GLY E:139 E:139 0.0 0.0 E -125.9 129.0 NA NA NA
GLY F:139 F:139 0.0 0.0 E -139.1 130.8 NA NA NA
GLY G:139 G:139 0.0 0.0 E -137.7 129.1 NA NA NA
GLY H:139 H:139 0.0 0.0 E -128.4 140.7 NA NA NA
5nkn 1 P80188 86.21 2e-106 X-RAY
 2018-04-04 GLY A:135 A:139 0.0 0.0 E -131.7 147.2 0.0 0.0 0.0 HOH
 6.943
 O
 O
6gqz 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 GLY A:135 A:139 0.0 0.0 E -127.4 147.0 0.0 0.0 0.0 HOH
 4.894
 O
 O
GLY B:135 B:139 0.0 0.0 E -127.7 148.1 NA NA NA
6gr0 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 GLY A:135 A:139 0.0 0.0 E -129.4 141.9 0.0 0.0 0.0 HOH
 4.570
 O
 O
GLY B:135 B:139 0.0 0.0 E -127.9 143.1 NA NA NA
GLY C:135 C:139 0.0 0.0 E -128.2 143.6 NA NA NA
4iax 1 P80188 81.46 3e-103 X-RAY
 2013-06-19 GLY A:139 A:139 0.0 0.0 E -130.4 147.1 0.0 0.0 0.0 LIZ
HOH
 9.630
4.946
 N
O
 O7
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p80188-f1 1 P80188 100.0 1e-149 GLY A:159 A:159 0.0 0.0 E -124.3 146.1