Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 130914545 . G A CCDS6892.1:NM_005564.3:c.559Gtc>Atc_NP_005555.2:p.187V>I Homo sapiens lipocalin 2 (LCN2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3hwe 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 VAL A:187 A:167 17.0 0.11 E -130.0 154.4 17.0 0.11 0.0 RKS
HOH
 6.889
6.249
 CG2
O
 O8
O
VAL B:187 B:167 20.0 0.129 E -127.5 154.4 NA NA NA
VAL C:187 C:167 12.0 0.077 E -125.0 149.2 NA NA NA
3hwf 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 VAL A:187 A:167 15.0 0.097 E -121.2 158.9 15.0 0.097 0.0 CL
 8.639
 CG2
 CL
VAL B:187 B:167 21.0 0.135 E -143.3 144.0 NA NA NA
VAL C:187 C:167 13.0 0.084 E -139.4 144.7 NA NA NA
3hwg 1 P80188 99.49 4e-148 X-RAY
 2010-06-02 VAL A:187 A:167 14.0 0.09 E -124.8 153.4 14.0 0.09 0.0 QED
SO4
SO4
HOH
 9.862
7.380
9.898
3.625
 CG2
CG2
CG2
CA
 O19
O4
O4
O
VAL B:187 B:167 20.0 0.129 E -129.7 147.4 NA NA NA
VAL C:187 C:167 14.0 0.09 E -124.6 144.7 NA NA NA
3u0d 1 P80188 99.49 4e-148 X-RAY
 2011-10-12 VAL A:187 A:167 22.0 0.142 E -129.3 161.4 22.0 0.142 0.0 HOH
 3.971
 CG1
 O
VAL B:187 B:167 17.0 0.11 E -122.0 160.0 NA NA NA
VAL C:187 C:167 23.0 0.148 E -124.2 155.7 NA NA NA
VAL D:187 D:167 19.0 0.123 E -129.7 151.7 NA NA NA
3cbc 1 P80188 98.99 1e-147 X-RAY
 2008-09-09 VAL A:187 A:167 16.0 0.103 E -121.1 154.4 NA NA NA
VAL B:187 B:167 11.0 0.071 E -124.5 155.2 11.0 0.071 0.0 DBS
HOH
 7.704
6.188
 CG2
O
 O15
O
VAL C:187 C:167 15.0 0.097 E -123.0 153.6 NA NA NA
3cmp 1 P80188 98.99 3e-147 X-RAY
 2009-05-12 VAL A:187 A:167 14.0 0.09 E -117.2 153.3 14.0 0.09 0.0 NA
HOH
 8.340
7.091
 CG2
C
 NA
O
VAL B:187 B:167 21.0 0.135 E -98.9 140.0 NA NA NA
VAL C:187 C:167 13.0 0.084 E -124.2 147.1 NA NA NA
3i0a 1 P80188 98.99 3e-147 X-RAY
 2010-06-09 VAL A:187 A:167 14.0 0.09 E -113.8 150.0 14.0 0.09 0.0 3ET
HOH
 8.076
3.946
 CG2
CG1
 O33
O
VAL B:187 B:167 48.0 0.31 E -117.7 148.0 NA NA NA
VAL C:187 C:167 11.0 0.071 E -124.6 155.1 NA NA NA
3hwd 1 P80188 98.48 1e-146 X-RAY
 2010-06-02 VAL A:187 A:167 10.0 0.065 E -126.7 152.6 10.0 0.065 0.0 HOH
 3.621
 CA
 O
VAL B:187 B:167 24.0 0.155 E -108.1 152.5 NA NA NA
VAL C:187 C:167 14.0 0.09 E -126.5 150.5 NA NA NA
3by0 1 P80188 98.48 9e-146 X-RAY
 2008-09-09 VAL A:187 A:167 15.0 0.097 E -117.6 153.9 15.0 0.097 0.0 DBS
HOH
 9.299
3.580
 CG2
CA
 O10
O
VAL B:187 B:167 20.0 0.129 E -122.3 151.7 NA NA NA
VAL C:187 C:167 10.0 0.065 E -119.3 154.5 NA NA NA
1dfv 1 P80188 100.0 2e-132 X-RAY
 2000-03-06 VAL A:167 A:167 11.0 0.071 E -136.2 155.2 11.0 0.071 0.0 HOH
 4.482
 CG2
 O
VAL B:167 B:167 13.0 0.084 E -130.8 162.5 NA NA NA
1l6m 1 P80188 98.88 3e-132 X-RAY
 2003-03-11 VAL A:169 A:167 15.0 0.097 E -125.9 166.5 15.0 0.097 0.0 DBS
HOH
 9.674
5.860
 CG2
O
 O10
O
VAL B:169 B:167 17.0 0.11 E -130.4 147.4 NA NA NA
VAL C:169 C:167 18.0 0.116 E -133.3 157.4 NA NA NA
4k19 1 P80188 98.88 3e-132 X-RAY
 2013-07-31 VAL A:169 A:167 18.0 0.116 E -131.1 138.8 18.0 0.116 0.0 SO4
HOH
 7.931
3.971
 CG1
CG2
 O1
O
VAL B:169 B:167 35.0 0.226 B -112.9 149.8 NA NA NA
VAL C:169 C:167 13.0 0.084 E -122.2 147.2 NA NA NA
4zfx 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 11.0 0.071 E -126.3 155.8 11.0 0.071 0.0 HOH
 9.957
 CG2
 O
VAL B:169 B:167 14.0 0.09 E -125.3 150.1 14.0 0.09 0.0
VAL C:169 C:167 13.0 0.084 E -126.5 151.4 13.0 0.084 0.0 HOH
 9.864
 O
 O
4zhc 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 15.0 0.097 E -130.6 145.5 15.0 0.097 0.0 TC2
HOH
 8.023
3.645
 CG1
CA
 C37
O
VAL B:169 B:167 17.0 0.11 E -131.3 144.7 NA NA NA
VAL C:169 C:167 15.0 0.097 E -131.4 146.5 NA NA NA
4zhd 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 17.0 0.11 E -130.5 150.6 17.0 0.11 0.0 4OZ
HOH
 8.586
3.558
 CG2
CA
 O26
O
VAL B:169 B:167 17.0 0.11 E -128.7 147.4 NA NA NA
VAL C:169 C:167 12.0 0.077 E -130.1 149.5 NA NA NA
4zhf 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 18.0 0.116 E -131.2 156.2 18.0 0.116 0.0 4OL
HOH
 8.671
3.449
 CG2
CA
 C12
O
VAL B:169 B:167 16.0 0.103 E -132.3 155.7 NA NA NA
VAL C:169 C:167 15.0 0.097 E -130.7 156.2 NA NA NA
VAL D:169 D:167 16.0 0.103 E -130.9 157.1 NA NA NA
VAL E:169 E:167 20.0 0.129 E -130.1 148.6 NA NA NA
VAL F:169 F:167 15.0 0.097 E -129.3 155.1 NA NA NA
4zhg 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 18.0 0.116 E -132.7 150.7 18.0 0.116 0.0 4OL
HOH
 8.538
3.497
 CG2
CA
 C12
O
VAL B:169 B:167 17.0 0.11 E -130.9 150.9 NA NA NA
VAL C:169 C:167 15.0 0.097 E -130.9 152.4 NA NA NA
VAL D:169 D:167 11.0 0.071 E -130.9 153.2 NA NA NA
VAL E:169 E:167 16.0 0.103 E -130.2 144.0 NA NA NA
VAL F:169 F:167 16.0 0.103 E -130.3 150.0 NA NA NA
4zhh 1 P80188 98.88 3e-132 X-RAY
 2015-08-05 VAL A:169 A:167 18.0 0.116 E -131.8 154.1 18.0 0.116 0.0 4OL
HOH
 8.477
3.600
 CG2
CA
 C12
O
VAL B:169 B:167 18.0 0.116 E -130.7 153.4 NA NA NA
VAL C:169 C:167 14.0 0.09 E -130.2 154.2 NA NA NA
VAL D:169 D:167 12.0 0.077 E -129.4 153.1 NA NA NA
VAL E:169 E:167 21.0 0.135 E -128.7 148.3 NA NA NA
VAL F:169 F:167 16.0 0.103 E -129.2 154.3 NA NA NA
5khp 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 VAL A:169 A:167 12.0 0.077 E -132.9 146.2 12.0 0.077 0.0 HOH
 4.275
 CA
 O
VAL B:169 B:167 19.0 0.123 E -132.4 145.1 NA NA NA
VAL C:169 C:167 10.0 0.065 E -133.8 144.8 NA NA NA
5kic 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 VAL A:169 A:167 15.0 0.097 E -134.6 144.2 15.0 0.097 0.0 4OL
HOH
 8.517
9.680
 CG2
CG2
 C12
O
VAL B:169 B:167 15.0 0.097 E -136.8 139.6 NA NA NA
VAL C:169 C:167 14.0 0.09 E -137.1 141.8 NA NA NA
5kid 1 P80188 98.88 3e-132 X-RAY
 2017-04-26 VAL A:169 A:167 18.0 0.116 E -128.3 151.6 18.0 0.116 0.0 HOH
 3.578
 CA
 O
VAL B:169 B:167 15.0 0.097 E -125.3 147.6 NA NA NA
VAL C:169 C:167 15.0 0.097 E -128.8 149.1 NA NA NA
3tzs 1 P80188 98.88 4e-132 X-RAY
 2011-10-12 VAL A:168 A:167 11.0 0.071 E -132.1 149.4 11.0 0.071 0.0 PHU
HOH
 9.517
3.445
 CG2
CA
 N2
O
VAL B:168 B:167 16.0 0.103 E -136.6 135.7 NA NA NA
VAL C:168 C:167 11.0 0.071 E -127.1 149.1 NA NA NA
1x71 1 P80188 99.44 5e-132 X-RAY
 2005-01-18 VAL A:167 A:167 15.0 0.097 E -132.7 156.7 15.0 0.097 0.0 HOH
 3.385
 CA
 O
VAL B:167 B:167 16.0 0.103 E -134.8 151.5 NA NA NA
VAL C:167 C:167 9.0 0.058 E -122.9 156.7 NA NA NA
1x89 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 VAL A:167 A:167 16.0 0.103 E -126.5 160.9 16.0 0.103 0.0 CM1
HOH
 9.809
6.101
 CG2
O
 C13
O
VAL B:167 B:167 25.0 0.161 E -137.2 153.2 NA NA NA
VAL C:167 C:167 7.0 0.045 E -127.6 154.1 NA NA NA
1x8u 1 P80188 99.44 5e-132 X-RAY
 2005-01-25 VAL A:167 A:167 18.0 0.116 E -126.3 165.8 18.0 0.116 0.0 CM2
HOH
 9.673
6.164
 CG2
O
 C13
O
VAL B:167 B:167 23.0 0.148 E -128.6 149.0 NA NA NA
VAL C:167 C:167 15.0 0.097 E -122.3 163.2 NA NA NA
3fw4 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 VAL A:167 A:167 17.0 0.11 E -125.4 150.8 17.0 0.11 0.0 HOH
 3.493
 CA
 O
VAL B:167 NA:NA DO NA DO DO DO NA NA NA
VAL C:167 C:167 12.0 0.077 E -121.0 150.4 NA NA NA
3fw5 1 P80188 99.44 5e-132 X-RAY
 2010-05-05 VAL A:167 A:167 19.0 0.123 E -124.4 149.4 19.0 0.123 0.0 HOH
 3.570
 CA
 O
VAL B:167 B:167 34.0 0.219 B -131.9 149.9 NA NA NA
VAL C:167 C:167 14.0 0.09 E -117.8 149.6 NA NA NA
3k3l 1 P80188 99.44 5e-132 X-RAY
 2010-08-18 VAL A:167 A:167 15.0 0.097 E -120.8 147.9 15.0 0.097 0.0 DBS
DBH
HOH
 9.058
9.744
6.031
 CG2
CG2
O
 O15
O9
O
VAL B:167 B:167 99.0 0.639 360.0 139.0 NA NA NA
VAL C:167 C:167 12.0 0.077 E -112.9 148.5 NA NA NA
3pec 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 VAL A:167 A:167 15.0 0.097 E -122.3 151.0 15.0 0.097 0.0 HOH
 3.425
 CA
 O
VAL B:167 B:167 26.0 0.168 E -107.7 152.1 NA NA NA
VAL C:167 C:167 14.0 0.09 E -125.0 148.9 NA NA NA
3ped 1 P80188 99.44 5e-132 X-RAY
 2011-10-05 VAL A:167 A:167 18.0 0.116 E -122.3 148.0 18.0 0.116 0.0 HOH
 3.552
 CA
 O
VAL B:167 B:167 20.0 0.129 E -128.1 149.6 NA NA NA
VAL C:167 C:167 16.0 0.103 E -124.0 152.4 NA NA NA
3tf6 1 P80188 98.88 5e-132 X-RAY
 2011-09-07 VAL A:168 A:167 17.0 0.11 E -131.4 145.1 17.0 0.11 0.0 HOH
 3.570
 CG2
 O
VAL B:168 B:167 13.0 0.084 E -132.3 145.8 NA NA NA
VAL C:168 C:167 11.0 0.071 E -131.4 147.5 NA NA NA
6o5d 1 P80188 99.43 7e-129 X-RAY
 2019-09-11 VAL A:163 A:167 19.0 0.123 E -125.6 148.8 19.0 0.123 0.0 HOH
 8.024
 CG2
 O
VAL B:163 B:167 37.0 0.239 E -125.5 144.4 NA NA NA
VAL C:163 C:167 18.0 0.116 E -126.3 146.0 NA NA NA
5mhh 1 P80188 96.63 1e-127 X-RAY
 2017-10-11 VAL A:167 A:167 6.0 0.039 E -119.5 135.7 6.0 0.039 0.0 HOH
 3.489
 CA
 O
6qmu 1 P80188 96.63 1e-127 X-RAY
 2019-08-28 VAL A:167 A:167 4.0 0.026 E -123.4 137.4 4.0 0.026 0.0 HOH
 3.529
 CA
 O
VAL B:167 B:167 10.0 0.065 E -124.3 139.1 NA NA NA
3t1d 1 P80188 97.78 1e-120 X-RAY
 2011-08-17 VAL A:187 A:167 10.0 0.065 E -121.2 151.6 10.0 0.065 0.0 HOH
 5.966
 C
 O
VAL B:187 B:167 16.0 0.103 E -128.9 141.7 NA NA NA
VAL C:187 C:167 16.0 0.103 E -125.8 144.7 NA NA NA
3dsz 1 ? 91.57 4e-120 X-RAY
 2009-05-19 VAL A:167 A:167 45.0 0.29 E -129.8 141.9 45.0 0.29 0.0 LIZ
HOH
 7.105
3.251
 CG1
CG1
 O2
O
VAL B:167 B:167 48.0 0.31 E -140.2 144.7 NA NA NA
3dtq 1 P80188 91.57 4e-120 X-RAY
 2009-05-12 VAL A:167 A:167 53.0 0.342 E -111.0 152.3 53.0 0.342 0.0 HOH
 3.677
 CA
 O
VAL B:167 B:167 60.0 0.387 E -130.2 143.4 NA NA NA
VAL C:167 C:167 35.0 0.226 E -142.3 149.8 NA NA NA
5n47 1 P80188 90.45 6e-118 X-RAY
 2018-02-14 VAL A:167 A:167 11.0 0.071 E -131.7 142.8 11.0 0.071 0.0
VAL C:167 C:167 8.0 0.052 E -136.0 136.4 NA NA NA
VAL E:167 E:167 12.0 0.077 E -126.7 150.8 NA NA NA
1qqs 1 P80188 97.7 4e-116 X-RAY
 2000-04-21 VAL A:164 A:167 12.0 0.077 E -115.3 153.6 12.0 0.077 0.0 HOH
 3.454
 CG1
 O
5jr8 1 P80188 94.38 3e-115 X-RAY
 2016-09-28 VAL A:167 A:167 14.0 0.09 E -130.7 161.1 14.0 0.09 0.0 HOH
 6.011
 O
 O
VAL B:167 B:167 14.0 0.09 E -127.9 158.9 NA NA NA
4mvl 1 P80188 89.33 1e-114 X-RAY
 2015-08-12 VAL A:167 A:167 27.0 0.174 E -116.2 136.5 25.0 0.161 0.013 E:P05067:0.013
 HOH
 3.879
 CG1
 O
VAL B:167 B:167 43.0 0.277 E -144.8 150.9 NA NA NA
VAL C:167 C:167 36.0 0.232 E -95.7 138.1 NA NA NA
VAL D:167 D:167 33.0 0.213 E -130.7 133.8 NA NA NA
4mvi 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 VAL A:167 A:167 16.0 0.103 E -129.0 141.7 16.0 0.103 0.0 HOH
 3.684
 CA
 O
4mvk 1 P80188 89.33 9e-114 X-RAY
 2015-08-12 VAL A:167 A:167 27.0 0.174 E -129.7 137.6 27.0 0.174 0.0 HOH
 3.795
 CA
 O
5n48 1 P80188 88.2 1e-113 X-RAY
 2018-02-14 VAL A:167 A:167 74.0 0.477 E -124.6 152.5 74.0 0.477 0.0 HOH
 3.200
 CG1
 O
VAL C:167 C:167 59.0 0.381 E -135.8 141.7 NA NA NA
4gh7 1 P80188 88.2 1e-113 X-RAY
 2012-12-26 VAL A:167 A:167 34.0 0.219 E -129.0 143.3 34.0 0.219 0.0 HOH
 6.772
 N
 O
VAL C:167 C:167 30.0 0.194 E -114.1 137.7 NA NA NA
6s8v 1 P80188 88.2 9e-113 X-RAY
 2020-03-04 VAL A:167 A:167 3.0 0.019 E -127.6 157.5 3.0 0.019 0.0 HOH
 3.546
 CA
 O
VAL C:167 C:167 4.0 0.026 E -127.9 159.4 NA NA NA
6sua 1 P80188 88.76 2e-112 X-RAY
 2020-06-17 VAL A:167 A:167 42.0 0.271 E -131.3 159.8 42.0 0.271 0.0 HOH
 9.953
 CG2
 O
VAL C:167 C:167 43.0 0.277 E -131.6 160.1 NA NA NA
4iaw 1 P80188 87.08 3e-112 X-RAY
 2013-06-19 VAL A:167 A:167 53.0 0.342 E -136.3 150.5 53.0 0.342 0.0 LIZ
HOH
 7.170
3.984
 CG2
CA
 O1
O
VAL B:167 B:167 46.0 0.297 E -118.4 156.3 NA NA NA
VAL C:167 C:167 44.0 0.284 E -167.0 136.1 NA NA NA
6z2c 1 P80188 88.2 4e-111 X-RAY
 2021-05-26 VAL A:167 A:167 56.0 0.361 E -140.5 147.2 56.0 0.361 0.0 HOH
 3.884
 CA
 O
VAL B:167 B:167 65.0 0.419 E -140.2 146.8 NA NA NA
VAL C:167 C:167 60.0 0.387 E -139.7 146.4 NA NA NA
6z6z 1 P80188 86.52 3e-110 X-RAY
 2021-06-09 VAL A:168 A:167 14.0 0.09 E -129.5 142.3 14.0 0.09 0.0 HOH
 3.544
 CG1
 O
4qae 2 P80188 85.39 3e-109 X-RAY
 2015-05-06 VAL G:167 A:167 8.0 0.052 E -126.3 141.4 8.0 0.052 0.0 HOH
 3.462
 CG2
 O
VAL H:167 B:167 9.0 0.058 E -124.3 141.6 NA NA NA
VAL I:167 C:167 8.0 0.052 E -129.8 143.0 NA NA NA
VAL J:167 D:167 7.0 0.045 E -127.3 137.9 NA NA NA
VAL K:167 E:167 8.0 0.052 E -124.1 141.9 NA NA NA
VAL L:167 F:167 8.0 0.052 E -132.2 138.1 NA NA NA
3bx7 2 ? 83.15 4e-108 X-RAY
 2009-01-20 VAL B:167 A:167 16.0 0.103 E -126.8 150.5 13.0 0.084 0.019 A:P16410:0.019
 HOH
 3.268
 CA
 O
3bx8 1 ? 83.15 4e-108 X-RAY
 2009-01-20 VAL A:167 A:167 16.0 0.103 E -129.9 155.0 16.0 0.103 0.0 1PE
HOH
 8.208
3.495
 CG2
CA
 C16
O
VAL B:167 B:167 17.0 0.11 E -131.3 153.8 NA NA NA
VAL C:167 C:167 20.0 0.129 E -129.4 154.3 NA NA NA
VAL D:167 D:167 18.0 0.116 E -130.1 154.3 NA NA NA
VAL E:167 E:167 19.0 0.123 E -131.7 153.6 NA NA NA
VAL F:167 F:167 17.0 0.11 E -131.0 153.4 NA NA NA
VAL G:167 G:167 15.0 0.097 E -130.7 154.2 NA NA NA
VAL H:167 H:167 19.0 0.123 E -131.6 154.0 NA NA NA
5nkn 1 P80188 86.21 2e-106 X-RAY
 2018-04-04 VAL A:163 A:167 15.0 0.097 E -115.4 137.0 15.0 0.097 0.0 LOC
HOH
 9.459
4.186
 O
CG1
 C4
O
6gqz 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 VAL A:163 A:167 19.0 0.123 E -128.6 137.9 19.0 0.123 0.0 HOH
 3.577
 CA
 O
VAL B:163 B:167 17.0 0.11 E -122.0 134.9 NA NA NA
6gr0 1 P80188 85.63 7e-106 X-RAY
 2018-08-15 VAL A:163 A:167 11.0 0.071 E -130.9 137.9 11.0 0.071 0.0 F8W
HOH
 7.161
3.783
 CB
CA
 CAN
O
VAL B:163 B:167 27.0 0.174 E -130.3 137.2 NA NA NA
VAL C:163 C:167 27.0 0.174 E -131.7 137.5 NA NA NA
4iax 1 P80188 81.46 3e-103 X-RAY
 2013-06-19 VAL A:167 A:167 40.0 0.258 E -140.8 157.4 40.0 0.258 0.0 LIZ
HOH
 7.084
3.362
 CG2
CA
 O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p80188-f1 1 P80188 100.0 1e-149 VAL A:187 A:187 12.0 0.077 E -132.0 134.3