Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 15468828 . T A CCDS6479.1:NM_001128217.1:c.1220aAa>aTa_NP_001121689.1:p.407K>I Homo sapiens PC4 and SFRS1 interacting protein 1 (PSIP1), transcript variant 2, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6s01 7 O75475 100.0 0.0 EM
 2019-12-18 LYS K:407 NA:NA DO NA DO DO DO NA NA NA
6tvm 1 O75475 100.0 4e-84 NMR
 2020-09-09 LYS A:68 A:407 149.0 0.745 -176.2 135.7 80.0 0.4 0.345 B:O75475:0.345
LYS B:68 B:407 154.0 0.77 -176.7 134.4 77.0 0.385 0.385 A:O75475:0.385
2mtn 1 Q03164,O75475 100.0 1e-68 NMR
 2014-12-03 LYS A:129 A:407 146.0 0.73 -119.2 -14.0 146.0 0.73 0.0
6emq 1 O75475,Q03164 100.0 2e-65 NMR
 2018-08-01 LYS A:69 A:407 131.0 0.655 T -60.3 -25.2 131.0 0.655 0.0
6emr 1 O75475,Q96ST2 93.46 4e-65 NMR
 2018-07-25 LYS A:69 A:407 39.0 0.195 T -55.3 -22.2 39.0 0.195 0.0
5yi9 1 O75475,Q96GN5 100.0 1e-64 NMR
 2018-08-15 LYS A:69 A:407 127.0 0.635 T -71.9 -15.6 127.0 0.635 0.0
6emp 1 O75475,Q7Z3K3 100.0 6e-64 NMR
 2018-07-25 LYS A:69 A:407 91.0 0.455 T -71.3 -19.2 91.0 0.455 0.0
6emo 1 O75475,Q96GN5 95.28 6e-64 NMR
 2018-07-25 LYS A:69 A:407 122.0 0.61 T -71.6 -17.5 122.0 0.61 0.0
2b4j 2 O75475 98.97 2e-63 X-RAY
 2005-10-25 LYS C:63 C:407 153.0 0.765 T -69.1 -12.4 138.0 0.69 0.075 B:P12497:0.075
 HOH
 4.659
 O
 O
LYS D:63 D:407 165.0 0.825 T -67.5 -17.4 151.0 0.755 0.07 A:P12497:0.07
 HOH
 2.298
 O
 O
3f9k 2 O75475 98.89 2e-58 X-RAY
 2009-01-20 LYS C:61 C:407 152.0 0.76 T -59.5 -17.8 140.0 0.7 0.06 B:P04584:0.06
LYS F:61 G:407 146.0 0.73 T -58.2 -18.1 NA NA NA
LYS I:61 K:407 156.0 0.78 T -58.3 -18.4 NA NA NA
LYS L:61 O:407 154.0 0.77 T -59.0 -17.7 NA NA NA
LYS O:61 S:407 147.0 0.735 T -58.2 -18.8 NA NA NA
LYS R:61 W:407 144.0 0.72 T -58.8 -18.1 NA NA NA
LYS U:61 a:407 155.0 0.775 T -58.9 -17.6 NA NA NA
LYS X:61 e:407 148.0 0.74 T -58.3 -18.1 NA NA NA
LYS AA:61 i:407 153.0 0.765 T -59.0 -17.4 NA NA NA
LYS DA:61 m:407 148.0 0.74 T -58.2 -18.0 NA NA NA
LYS GA:61 q:407 149.0 0.745 T -58.6 -17.9 NA NA NA
LYS JA:61 u:407 150.0 0.75 T -57.5 -18.7 NA NA NA
3hpg 2 O75475 98.89 2e-58 X-RAY
 2009-07-28 LYS G:61 G:407 147.0 0.735 T -59.8 -24.5 144.0 0.72 0.015 F:P35956:0.015
LYS H:61 H:407 146.0 0.73 T -60.7 -23.4 146.0 0.73 0.0
LYS I:61 I:407 150.0 0.75 T -60.2 -24.5 NA NA NA
LYS J:61 J:407 149.0 0.745 T -60.9 -24.3 NA NA NA
LYS K:61 K:407 150.0 0.75 T -60.6 -23.5 150.0 0.75 0.0
LYS L:61 L:407 148.0 0.74 T -60.5 -24.6 146.0 0.73 0.01 A:P35956:0.01
3u88 3 O75475 100.0 3e-58 X-RAY
 2012-02-15 LYS D:61 C:407 137.0 0.685 T -72.2 22.7 137.0 0.685 0.0 GGB
GGB
 3.789
6.952
 CG
N
 OA2
OA2
LYS F:61 NA:NA DO NA DO DO DO NA NA NA
3hph 2 O75475 98.88 9e-58 X-RAY
 2009-07-28 LYS E:60 E:407 167.0 0.835 T -64.2 -4.7 128.0 0.64 0.195 A:P35956:0.195
LYS F:60 F:407 178.0 0.89 T -58.6 -3.4 131.0 0.655 0.235 C:P35956:0.235
 HOH
 9.561
 CB
 O
LYS G:60 G:407 182.0 0.91 T -58.9 -3.5 135.0 0.675 0.235 B:P35956:0.235
 HOH
 9.788
 CB
 O
LYS H:60 H:407 169.0 0.845 T -67.7 -9.0 133.0 0.665 0.18 D:P35956:0.18
5oym 1 O75475 100.0 2e-57 X-RAY
 2018-03-07 LYS A:87 H:407 161.0 0.805 -120.8 139.5 123.0 0.615 0.19 B:O75475:0.19
 HOH
 3.669
 CA
 O
LYS B:87 G:407 165.0 0.825 -152.0 118.8 149.0 0.745 0.08 A:O75475:0.08
 HOH
 2.952
 N
 O
LYS C:87 A:407 161.0 0.805 -163.8 143.1 142.0 0.71 0.095 D:O75475:0.095
 HOH
 3.346
 N
 O
LYS D:87 B:407 163.0 0.815 -113.0 123.5 130.0 0.65 0.165 C:O75475:0.165
 HOH
 3.879
 CG
 O
LYS E:87 C:407 170.0 0.85 -140.0 115.8 153.0 0.765 0.085 F:O75475:0.085
 HOH
 5.090
 N
 O
LYS F:87 D:407 167.0 0.835 -117.6 130.0 142.0 0.71 0.125 E:O75475:0.125
 HOH
 2.416
 O
 O
LYS G:87 E:407 160.0 0.8 -116.3 125.4 124.0 0.62 0.18 H:O75475:0.18
 HOH
 5.506
 O
 O
LYS H:87 F:407 175.0 0.875 -149.6 133.7 155.0 0.775 0.1 G:O75475:0.1
 HOH
 6.831
 O
 O
6zv0 1 O75475 100.0 8e-57 NMR
 2021-12-01 LYS A:68 A:407 187.0 0.935 T -64.9 5.6 187.0 0.935 0.0
6trj 1 O75475 100.0 3e-56 X-RAY
 2020-09-09 LYS A:68 A:68 83.0 NA -147.8 127.1 64.0 NA NA A:O75475:NA
 HOH
 2.759
 O
 O
2msr 2 O75475 100.0 1e-53 NMR
 2014-08-20 LYS B:69 B:407 190.0 0.95 T -70.9 -13.8 185.0 0.925 0.025 A:Q03164:0.025
2n3a 2 O75475 100.0 2e-50 NMR
 2015-08-19 LYS B:60 B:407 177.0 0.885 -106.7 -31.1 167.0 0.835 0.05 A:Q7Z3K3:0.05
5n88 2 O75475 100.0 4e-50 X-RAY
 2017-12-20 LYS B:61 D:407 164.0 0.82 T -71.7 -23.8 NA NA NA
5n88 3 O75475 98.73 3e-49 X-RAY
 2017-12-20 LYS D:63 E:407 169.0 0.845 T -64.6 -18.0 105.0 0.525 0.32 A:None:0.32
 HOH
 3.506
 NZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o75475-f1 1 O75475 100.0 0.0 LYS A:407 A:407 192.0 0.96 T -57.0 -17.8