Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 90344492 . A C CCDS6675.1:NM_001257971.1:c.626gAa>gCa_NP_001244900.1:p.209E>A Homo sapiens cathepsin L (CTSL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1cs8 1 P07711 99.37 0.0 X-RAY
 1999-08-23 GLU A:192 A:96 104.0 0.547 -136.2 -176.2 104.0 0.547 0.0 HOH
 2.173
 O
 H1
6jd8 1 P07711 98.42 0.0 X-RAY
 2020-02-05 GLU A:236 A:192 84.0 0.442 -130.0 177.9 84.0 0.442 0.0 EOH
EOH
EDO
HOH
 6.570
8.930
8.779
2.430
 O
O
HG2
O
 HO
H21
H22
O
6jd0 1 P07711 97.47 0.0 X-RAY
 2020-02-05 GLU A:236 A:192 88.0 0.463 -140.2 -176.9 88.0 0.463 0.0 PGE
PGE
EOH
HOH
 6.271
7.729
4.025
2.689
 OE1
OE2
O
HB2
 H1
H6
HO
O
1cjl 1 P07711 98.4 0.0 X-RAY
 1997-08-12 GLU A:188 A:96 87.0 0.458 -121.4 -174.1 87.0 0.458 0.0 HOH
 2.547
 OE1
 H1
3hwn 1 P07711 99.61 0.0 X-RAY
 2009-09-15 GLU A:134 A:96 95.0 0.5 -142.1 179.1 95.0 0.5 0.0 HOH
 2.416
 OE2
 O
GLU B:134 B:96 113.0 0.595 -128.4 177.4 NA NA NA
GLU C:134 C:96 97.0 0.511 -132.0 -151.8 NA NA NA
GLU D:134 D:96 96.0 0.505 -91.9 -175.9 NA NA NA
3of8 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 GLU A:97 A:97 78.0 0.411 -118.0 168.7 78.0 0.411 0.0 HOH
 6.031
 CG
 O
3of9 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 GLU A:97 A:97 92.0 0.484 -139.4 174.3 92.0 0.484 0.0
2xu3 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLU A:96 A:96 74.0 0.389 -130.8 173.7 74.0 0.389 0.0 HOH
 2.667
 HB3
 O
2xu4 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLU A:96 A:96 55.0 0.289 -154.3 174.4 55.0 0.289 0.0 HOH
 2.659
 O
 O
2xu5 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLU A:96 A:96 78.0 0.411 -128.6 -179.9 78.0 0.411 0.0 GOL
HOH
 7.475
2.889
 OE2
O
 O1
O
2yj2 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLU A:96 A:96 75.0 0.395 -133.0 173.6 75.0 0.395 0.0 HOH
 2.770
 HB2
 O
2yj8 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLU A:96 A:96 77.0 0.405 -134.0 174.1 77.0 0.405 0.0 HOH
 2.531
 HB2
 O
2yj9 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLU A:96 A:96 74.0 0.389 -132.8 173.3 74.0 0.389 0.0 HOH
 2.604
 HB2
 O
2yjb 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLU A:96 A:96 89.0 0.468 -133.5 174.0 89.0 0.468 0.0 HOH
 2.425
 HB3
 O
2yjc 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLU A:96 A:96 78.0 0.411 -129.7 175.2 78.0 0.411 0.0 HOH
 2.597
 HB2
 O
3bc3 1 P07711 100.0 3e-166 X-RAY
 2008-03-18 GLU A:96 A:96 76.0 0.4 -127.5 -177.6 76.0 0.4 0.0 HOH
 2.697
 O
 O
GLU B:96 B:96 70.0 0.368 -131.4 -178.2 NA NA NA
3h89 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLU A:96 A:96 82.0 0.432 -129.6 171.9 82.0 0.432 0.0 HOH
 4.870
 O
 O
GLU B:96 B:96 83.0 0.437 -128.6 172.8 NA NA NA
GLU C:96 C:96 85.0 0.447 -119.1 -179.4 NA NA NA
GLU D:96 D:96 85.0 0.447 -129.8 169.9 NA NA NA
GLU E:96 E:96 80.0 0.421 -130.5 162.5 NA NA NA
GLU F:96 F:96 77.0 0.405 -124.0 -178.5 NA NA NA
3h8b 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLU A:96 A:96 91.0 0.479 -136.3 -179.8 91.0 0.479 0.0 HOH
 2.587
 O
 O
GLU B:96 B:96 89.0 0.468 -135.9 179.5 NA NA NA
GLU C:96 C:96 92.0 0.484 -137.0 178.5 NA NA NA
GLU D:96 D:96 92.0 0.484 -133.4 179.6 NA NA NA
GLU E:96 E:96 74.0 0.389 -130.6 -177.8 NA NA NA
GLU F:96 F:96 92.0 0.484 -140.3 -175.7 NA NA NA
3h8c 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLU A:96 A:96 72.0 0.379 -116.1 -173.2 72.0 0.379 0.0 HOH
 2.878
 CG
 O
GLU B:96 B:96 80.0 0.421 -108.5 -173.6 NA NA NA
4axl 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 GLU A:96 A:96 83.0 0.437 -136.7 178.0 83.0 0.437 0.0 HOH
 2.750
 O
 O
4axm 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 GLU A:96 A:96 86.0 0.453 -108.7 -167.4 86.0 0.453 0.0
GLU B:96 B:96 85.0 0.447 -149.7 -172.0 NA NA NA
GLU C:96 F:96 87.0 0.458 -132.0 -174.5 NA NA NA
GLU D:96 I:96 78.0 0.411 -98.5 176.2 NA NA NA
GLU E:96 L:96 87.0 0.458 -131.4 -156.9 NA NA NA
GLU F:96 O:96 84.0 0.442 -107.0 -164.8 NA NA NA
5f02 1 P07711 100.0 3e-166 X-RAY
 2016-02-24 GLU A:96 A:96 76.0 0.4 -133.0 174.1 76.0 0.4 0.0 HOH
 2.578
 HB3
 O
5mae 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 GLU A:96 A:96 79.0 0.416 -135.2 178.5 79.0 0.416 0.0 HOH
 2.739
 OE1
 O
5maj 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 GLU A:96 A:96 79.0 0.416 -133.1 171.7 79.0 0.416 0.0 HOH
 2.518
 O
 O
5mqy 1 P07711 100.0 3e-166 X-RAY
 2017-03-22 GLU A:96 A:96 77.0 0.405 -132.8 176.8 77.0 0.405 0.0 EDO
HOH
 5.391
2.735
 O
O
 O2
O
6ezp 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLU A:96 A:96 110.0 0.579 -134.0 -167.7 110.0 0.579 0.0 GOL
HOH
 9.826
2.715
 OE1
OE2
 O3
O
6ezx 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLU A:96 A:96 74.0 0.389 -120.9 -161.6 74.0 0.389 0.0 HOH
 7.976
 O
 O
GLU B:96 B:96 92.0 0.484 -131.1 176.5 92.0 0.484 0.0 HOH
 4.079
 CB
 O
6f06 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLU A:96 A:96 81.0 0.426 -145.1 173.1 81.0 0.426 0.0 ZN
HOH
 2.054
2.380
 OE1
OE1
 ZN
O
GLU B:96 B:96 84.0 0.442 -132.2 -176.6 NA NA NA
2nqd 2 P07711 99.55 1e-165 X-RAY
 2007-07-24 GLU B:97 B:96 78.0 0.411 -134.8 174.7 78.0 0.411 0.0 HOH
 2.502
 OE1
 O
2xu1 1 P07711 99.55 2e-165 X-RAY
 2011-01-12 GLU A:96 A:96 83.0 0.437 -134.5 170.6 83.0 0.437 0.0 HOH
 2.980
 OE1
 O
GLU B:96 B:96 63.0 0.332 -147.6 177.5 NA NA NA
GLU C:96 C:96 56.0 0.295 -146.6 170.5 NA NA NA
GLU D:96 D:96 49.0 0.258 -138.9 178.3 NA NA NA
3hha 1 P07711 99.55 2e-165 X-RAY
 2009-06-23 GLU A:96 A:96 83.0 0.437 -134.3 172.0 83.0 0.437 0.0 HOH
 2.729
 O
 O
GLU B:96 B:96 78.0 0.411 -136.6 173.8 NA NA NA
GLU C:96 C:96 105.0 0.553 -136.4 -176.8 NA NA NA
GLU D:96 D:96 95.0 0.5 -129.4 175.7 NA NA NA
3iv2 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 GLU A:96 A:96 101.0 0.532 -125.8 -175.3 101.0 0.532 0.0 HOH
 3.355
 OE1
 O
GLU B:96 B:96 102.0 0.537 -121.4 -175.6 102.0 0.537 0.0 NA
HOH
 6.098
7.753
 O
O
 NA
O
3k24 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 GLU A:96 A:96 73.0 0.384 -124.7 172.5 73.0 0.384 0.0 HOH
 2.982
 OE2
 O
GLU B:96 B:96 64.0 0.337 -129.3 175.8 NA NA NA
3kse 1 P07711 99.09 8e-165 X-RAY
 2010-12-01 GLU A:96 A:96 76.0 0.4 -120.6 178.2 76.0 0.4 0.0 HOH
 2.550
 OE1
 O
GLU B:96 B:96 77.0 0.405 -125.5 176.2 NA NA NA
GLU C:96 C:96 78.0 0.411 -119.5 177.0 NA NA NA
2vhs 1 P07711 91.82 1e-145 X-RAY
 2008-03-11 GLU A:96 A:96 79.0 0.416 -130.5 176.2 79.0 0.416 0.0 HOH
 2.616
 O
 O
GLU B:96 B:96 81.0 0.426 -142.9 177.6 81.0 0.426 0.0 HOH
 2.470
 OE1
 O
GLU C:96 C:96 76.0 0.4 -128.5 175.6 76.0 0.4 0.0 HOH
 2.828
 O
 O
GLU D:96 D:96 87.0 0.458 -123.0 175.8 87.0 0.458 0.0 HOH
 2.653
 OE1
 O
1icf 1 P07711 100.0 1e-129 X-RAY
 2000-01-12 GLU A:96 A:96 79.0 0.416 -127.5 -169.4 79.0 0.416 0.0 HOH
 3.124
 CA
 O
GLU C:96 C:96 74.0 0.389 -126.2 -165.8 NA NA NA
1mhw 1 P07711 100.0 1e-129 X-RAY
 2002-12-11 GLU A:96 A:96 68.0 0.358 -134.4 173.8 68.0 0.358 0.0 HOH
 2.788
 O
 O
GLU C:96 B:96 94.0 0.495 -133.2 178.4 NA NA NA
5i4h 1 P07711 99.06 5e-73 X-RAY
 2016-04-13 GLU A:97 A:96 90.0 0.474 -122.5 178.9 90.0 0.474 0.0 SO4
SO4
HOH
 5.926
4.282
1.701
 N
O
OE1
 O2
O4
H2

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07711-f1 1 P07711 100.0 0.0 GLU A:209 A:209 74.0 0.389 -128.4 -177.1