Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 137300137 . G A CCDS35172.1:NM_002957.4:c.422cGc>cAc_NP_002948.1:p.141R>H Homo sapiens retinoid X receptor, alpha (RXRA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3dzu 1 P19793 100.0 0.0 X-RAY
 2008-10-28 ARG A:146 A:141 143.0 0.636 E -79.6 109.1 143.0 0.636 0.0 DG
DA
DC
ZN
 8.232
6.298
9.422
6.484
 O
O
O
N
 O3'
OP2
OP2
ZN
3dzy 1 P19793 100.0 0.0 X-RAY
 2008-10-28 ARG A:146 A:141 209.0 0.929 E -81.1 126.4 209.0 0.929 0.0 DG
DA
ZN
 8.791
6.461
6.269
 O
O
O
 O3'
OP2
ZN
3e00 1 P19793 100.0 0.0 X-RAY
 2008-10-28 ARG A:146 A:141 159.0 0.707 B -80.5 130.1 159.0 0.707 0.0 DG
DA
DC
ZN
 8.605
6.351
9.611
6.113
 O
O
NH1
O
 O3'
OP2
OP2
ZN
4nqa 1 P19793 100.0 0.0 X-RAY
 2014-02-26 ARG A:44 A:141 206.0 0.916 B -74.3 129.3 202.0 0.898 0.018 B:F1D8P7:0.018
 DG
DA
DC
ZN
 8.439
6.014
8.113
6.316
 O
O
NH1
O
 O3'
OP2
OP2
ZN
ARG G:44 H:141 209.0 0.929 B -76.2 121.4 NA NA NA
5uan 1 P19793 100.0 0.0 X-RAY
 2017-10-18 ARG A:44 A:141 211.0 0.938 B -65.2 145.2 211.0 0.938 0.0 DG
DA
DC
ZN
 8.575
6.082
7.284
6.360
 O
O
NH2
O
 O3'
OP2
OP2
ZN
1ynw 4 P19793 100.0 3e-73 X-RAY
 2005-02-15 ARG D:12 B:241 190.0 0.844 -48.6 145.3 190.0 0.844 0.0 DG
DA
DC
ZN
 8.711
6.226
9.587
5.904
 O
O
NH2
O
 O3'
OP2
OP2
ZN
1dsz 4 P19793 98.82 2e-62 X-RAY
 2000-07-10 ARG D:14 B:1241 149.0 0.662 E -61.7 148.6 149.0 0.662 0.0 DG
DA
DC
ZN
HOH
 8.308
6.365
6.502
6.101
2.764
 NH2
O
NH2
O
O
 O3'
OP2
OP2
ZN
O
4cn2 3 P19793 100.0 1e-61 X-RAY
 2015-02-18 ARG C:16 C:141 141.0 0.627 E -59.6 147.0 141.0 0.627 0.0 DG
DA
DA
ZN
MG
MG
HOH
 7.310
5.226
5.332
6.210
5.271
6.279
2.923
 NH1
NH1
NH1
O
O
CD
O
 O3'
OP2
OP2
ZN
MG
MG
O
ARG D:16 D:141 155.0 0.689 B -84.4 134.1 155.0 0.689 0.0 DG
DA
DC
ZN
HOH
 8.281
5.879
9.698
6.494
5.241
 O
O
CD
O
O
 O3'
OP2
OP2
ZN
O
4cn3 1 P19793 100.0 1e-61 X-RAY
 2015-02-18 ARG A:16 A:141 200.0 0.889 B -51.1 127.8 NA NA NA
ARG B:16 B:141 220.0 0.978 B -67.5 131.2 220.0 0.978 0.0 DG
DA
DA
ZN
HOH
 8.478
6.079
7.771
6.131
3.640
 O
O
NH1
O
N
 O3'
OP2
OP2
ZN
O
ARG C:16 C:141 142.0 0.631 B -62.9 129.8 142.0 0.631 0.0 DG
DA
DA
ZN
HOH
 8.497
6.185
9.907
6.337
2.741
 O
O
CD
O
NH2
 O3'
OP2
OP2
ZN
O
4cn5 1 P19793 100.0 1e-61 X-RAY
 2015-02-18 ARG A:16 A:141 147.0 0.653 E -67.6 151.7 147.0 0.653 0.0 DG
DA
DC
DC
ZN
CL
HOH
 6.835
4.763
4.131
9.679
6.117
9.672
2.674
 NH2
NH2
NH2
NH2
O
N
O
 O3'
O5'
OP2
OP2
ZN
CL
O
ARG B:16 B:141 211.0 0.938 B -53.1 140.6 211.0 0.938 0.0 DG
DA
DA
ZN
HOH
 8.441
6.062
9.555
6.076
3.363
 O
O
NH2
O
O
 O3'
OP2
OP2
ZN
O
4cn7 1 P19793 100.0 1e-61 X-RAY
 2015-02-18 ARG A:16 A:141 188.0 0.836 B -64.8 120.3 NA NA NA
ARG B:16 B:141 122.0 NA E -57.3 131.3 NA NA NA
ARG E:16 E:141 94.0 NA B -62.9 119.6 94.0 NA NA DG
DA
DC
ZN
HOH
 8.396
6.095
9.492
6.492
5.008
 O
O
CG
O
O
 O3'
OP2
OP2
ZN
O
ARG F:16 F:141 73.0 NA B -61.2 117.7 73.0 NA NA DG
DA
ZN
HOH
 8.495
6.183
6.478
3.175
 O
O
O
O
 O3'
OP2
ZN
O
6fbq 1 P19793 100.0 1e-61 X-RAY
 2018-12-05 ARG A:16 A:141 158.0 0.702 E -63.5 158.2 158.0 0.702 0.0 DA
DC
ZN
HOH
 3.014
3.170
5.989
1.934
 HH21
HH22
O
HH12
 H3'
OP2
ZN
O
ARG B:16 B:141 168.0 0.747 B -62.4 131.3 168.0 0.747 0.0 DG
DA
ZN
HOH
 7.861
6.033
6.034
2.560
 O
O
O
O
 H3'
OP2
ZN
O
6fbr 1 P19793 100.0 1e-61 X-RAY
 2018-12-05 ARG A:16 A:141 120.0 0.533 E -64.8 143.9 120.0 0.533 0.0 DG
DA
DC
ZN
HOH
 8.551
6.173
9.996
6.120
2.887
 O
O
CB
O
O
 O3'
OP2
OP2
ZN
O
ARG B:16 B:141 176.0 0.782 E -63.0 129.8 176.0 0.782 0.0 DG
DA
ZN
HOH
 8.196
5.818
6.360
2.851
 O
O
O
NH1
 O3'
OP2
ZN
O
6xwg 3 P19793 100.0 1e-61 X-RAY
 2020-09-09 ARG C:16 C:141 191.0 0.849 E -60.9 133.4 191.0 0.849 0.0 DG
DA
DA
ZN
HOH
 8.528
6.064
8.921
6.636
7.733
 O
O
CD
O
C
 O3'
OP2
OP2
ZN
O
6xwh 3 P19793 100.0 1e-61 X-RAY
 2020-09-09 ARG C:16 C:141 168.0 0.747 B -64.9 142.3 168.0 0.747 0.0 DG
DA
DC
DC
ZN
HOH
 8.698
6.391
7.056
9.018
6.052
8.450
 O
O
NH2
NH2
O
C
 O3'
OP2
OP2
N4
ZN
O
ARG D:16 D:141 193.0 0.858 E -59.2 131.3 193.0 0.858 0.0 DG
DG
DC
ZN
HOH
 8.684
6.340
9.777
6.274
7.440
 O
O
CD
O
N
 O3'
OP2
OP2
ZN
O
4cn3 2 P19793 98.8 8e-61 X-RAY
 2015-02-18 ARG D:16 D:141 164.0 0.729 B -70.9 140.9 NA NA NA
1rxr 1 P19793 98.8 3e-60 NMR
 1998-11-11 ARG A:12 A:141 159.0 0.707 B -69.9 125.9 159.0 0.707 0.0 ZN
 6.472
 O
 ZN
1by4 3 P19793 98.78 9e-60 X-RAY
 2000-01-12 ARG E:14 A:1141 202.0 0.898 B -65.2 134.2 202.0 0.898 0.0 DG
DA
DC
ZN
HOH
 8.388
6.045
9.989
6.145
3.306
 O
O
CD
O
O
 C3'
OP2
OP2
ZN
O
ARG F:14 B:1241 125.0 0.556 E -75.7 164.3 125.0 0.556 0.0 DG
DA
DC
ZN
HOH
 8.730
6.416
6.739
5.477
2.561
 O
O
NH2
O
N
 C3'
OP2
OP2
ZN
O
ARG G:14 C:2141 218.0 0.969 B -48.9 126.8 NA NA NA
ARG H:14 D:2241 90.0 0.4 E -79.9 150.7 NA NA NA
1r0n 3 P19793 100.0 1e-56 X-RAY
 2003-10-21 ARG C:12 A:107 211.0 0.938 B -71.2 150.8 205.0 0.911 0.027 D:P34021:0.027
 DG
DA
DC
ZN
HOH
 8.646
6.354
7.446
6.085
2.523
 O
O
NH1
O
NH2
 O3'
OP2
OP2
ZN
O
1r0o 3 P20153 85.37 2e-51 X-RAY
 2003-10-21 ARG C:17 A:13 204.0 0.907 B -64.9 124.9 202.0 0.898 0.009 D:P34021:0.009
 DG
DA
DC
ZN
HOH
 8.546
6.133
9.456
6.608
2.501
 O
O
CD
O
NE
 O3'
OP2
OP2
ZN
O
2han 3 P20153 81.61 3e-51 X-RAY
 2007-05-22 ARG C:19 A:13 189.0 0.84 B -69.3 129.9 188.0 0.836 0.004 D:P34021:0.004
 DG
DA
DA
ZN
HOH
 8.470
6.118
8.401
6.153
3.185
 O
O
NH2
O
O
 O3'
OP2
OP2
ZN
O
4umm 1 ? 87.18 5e-51 EM
 2014-06-25 ARG A:10 A:119 187.0 0.831 B -61.1 118.5 186.0 0.827 0.004 D:O18473:0.004
 DG
DA
DA
 8.328
5.962
8.398
 O
O
NH1
 O3'
OP2
OP2
2nll 3 P19793 100.0 5e-48 X-RAY
 1997-03-12 ARG C:7 A:141 201.0 0.893 -56.9 156.9 201.0 0.893 0.0 DG
DA
DC
ZN
HOH
 9.165
6.887
7.132
5.612
2.651
 O
O
NH1
O
NH1
 C3'
OP2
OP2
ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19793-f1 1 P19793 100.0 0.0 ARG A:141 A:141 200.0 0.889 B -62.4 125.3