Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 140711929 . G A CCDS7050.2:NM_024757.4:c.3413tGg>tAg_NP_079033.4:p.1138W>* Homo sapiens euchromatic histone lysine methyltransferase 1 (EHMT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2igq 1 Q9H9B1 100.0 0.0 X-RAY
 2006-10-24 TRP A:157 A:1107 13.0 0.051 E -77.5 147.1 13.0 0.051 0.0 SAH
HOH
 2.667
3.991
 O
CD1
 N
O
TRP B:157 B:1107 18.0 0.071 S 65.3 119.8 18.0 0.071 0.0 SAH
HOH
 2.827
2.918
 O
NE1
 N
O
2rfi 1 Q9H9B1 100.0 0.0 X-RAY
 2007-10-23 TRP A:157 A:1107 17.0 0.067 E -81.9 147.3 17.0 0.067 0.0 SAH
HOH
 2.802
2.881
 O
NE1
 N
O
TRP B:157 B:1107 31.0 0.122 E -83.8 145.1 NA NA NA
3mo0 1 Q9H9B1 100.0 0.0 X-RAY
 2010-06-30 TRP A:157 A:1107 4.0 0.016 E -114.4 148.9 4.0 0.016 0.0 SAH
HOH
 2.797
4.900
 N
O
 O
O
TRP B:157 B:1107 5.0 0.02 E -75.5 156.6 NA NA NA
3mo2 1 Q9H9B1 100.0 0.0 X-RAY
 2010-06-30 TRP A:157 A:1107 39.0 0.153 E -111.6 154.5 39.0 0.153 0.0 HOH
 3.367
 NE1
 O
TRP B:157 B:1107 34.0 0.133 E -110.6 150.0 NA NA NA
TRP C:157 C:1107 11.0 0.043 E -95.9 147.3 NA NA NA
TRP D:157 D:1107 14.0 0.055 E -88.9 160.2 NA NA NA
3mo5 1 Q9H9B1 100.0 0.0 X-RAY
 2010-06-30 TRP A:157 A:1107 42.0 0.165 E -129.4 146.2 42.0 0.165 0.0 HOH
 2.728
 N
 O
TRP B:157 B:1107 35.0 0.137 E -112.0 150.6 NA NA NA
TRP C:157 C:1107 15.0 0.059 E -91.4 154.2 NA NA NA
TRP D:157 D:1107 14.0 0.055 E -87.7 159.4 NA NA NA
3sw9 1 Q9H9B1 100.0 0.0 X-RAY
 2011-12-07 TRP A:157 A:1107 18.0 0.071 E -82.0 150.5 18.0 0.071 0.0 SFG
 3.047
 N
 O
TRP C:157 B:1107 12.0 0.047 E -74.6 149.5 NA NA NA
3swc 1 Q9H9B1 100.0 0.0 X-RAY
 2011-11-30 TRP A:157 A:1107 13.0 0.051 E -80.4 156.6 13.0 0.051 0.0 SAH
HOH
 2.754
5.310
 N
O
 O
O
TRP C:157 B:1107 13.0 0.051 E -88.5 157.1 NA NA NA
3hna 1 Q9H9B1 100.0 0.0 X-RAY
 2009-06-09 TRP A:159 A:1107 23.0 0.09 E -91.3 150.8 23.0 0.09 0.0 SAH
HOH
 2.743
3.565
 O
CD1
 N
O
TRP B:159 B:1107 16.0 0.063 E -86.4 150.5 NA NA NA
5ttg 1 Q9H9B1 100.0 0.0 X-RAY
 2017-02-01 TRP A:159 A:1138 14.0 0.055 E -79.8 151.5 14.0 0.055 0.0 SAM
UNX
HOH
 2.805
6.082
2.917
 N
N
NE1
 O
UNK
O
TRP B:159 B:1138 14.0 0.055 E -79.9 149.2 NA NA NA
5v9j 1 Q9H9B1 100.0 0.0 X-RAY
 2018-03-21 TRP A:159 A:1138 15.0 0.059 E -79.4 151.5 15.0 0.059 0.0 SAM
UNX
UNX
HOH
 2.805
6.038
6.093
2.840
 O
N
NE1
NE1
 N
UNK
UNK
O
TRP B:159 B:1138 13.0 0.051 E -79.7 143.7 13.0 0.051 0.0 SAM
UNX
HOH
 2.832
5.865
2.636
 O
N
NE1
 N
UNK
O
4i51 1 Q9H9B1 99.65 0.0 X-RAY
 2012-12-19 TRP A:158 A:1107 15.0 0.059 E -81.3 148.2 15.0 0.059 0.0 SAH
UNX
HOH
 2.849
8.170
2.955
 N
C
NE1
 OXT
UNK
O
TRP C:158 B:1107 9.0 0.035 E -83.1 147.2 9.0 0.035 0.0 SAH
HOH
 2.824
3.872
 N
CD1
 OXT
O
3fpd 1 Q9H9B1 100.0 0.0 X-RAY
 2009-02-17 TRP A:133 A:1107 12.0 0.047 E -81.4 143.9 12.0 0.047 0.0 SAH
HOH
 2.762
5.325
 N
CD1
 O
O
TRP B:133 B:1107 15.0 0.059 E -85.3 157.8 15.0 0.059 0.0 SAH
HOH
 2.657
5.950
 N
CZ3
 O
O
5tuz 1 Q9H9B1 100.0 0.0 X-RAY
 2017-02-22 TRP A:133 A:1138 13.0 0.051 E -84.3 151.3 13.0 0.051 0.0 SAM
HOH
 2.713
2.991
 N
NE1
 O
O
TRP B:133 B:1138 13.0 0.051 E -79.4 149.1 13.0 0.051 0.0 SAM
HOH
 2.769
3.684
 O
CD1
 N
O
5vsd 1 Q9H9B1 100.0 0.0 X-RAY
 2017-07-12 TRP A:133 A:1138 13.0 0.051 E -78.0 148.8 13.0 0.051 0.0 SAM
HOH
 2.766
2.966
 O
NE1
 N
O
TRP B:133 B:1138 13.0 0.051 E -78.1 148.7 13.0 0.051 0.0 SAM
HOH
 2.777
3.567
 O
CD1
 N
O
5vsf 1 Q9H9B1 100.0 0.0 X-RAY
 2017-07-12 TRP A:133 A:1138 13.0 0.051 E -80.8 148.5 13.0 0.051 0.0 SAM
HOH
 2.807
2.830
 O
NE1
 N
O
TRP B:133 B:1138 13.0 0.051 E -80.1 148.5 13.0 0.051 0.0 SAM
HOH
 2.817
2.923
 O
NE1
 N
O
6mbo 1 Q9H9B1 100.0 0.0 X-RAY
 2019-02-27 TRP A:133 A:1107 14.0 0.055 E -84.0 148.7 14.0 0.055 0.0 SAH
EDO
EDO
HOH
 2.809
4.783
8.298
2.824
 O
N
N
NE1
 N
O1
O1
O
TRP B:133 B:1107 9.0 0.035 E -81.5 152.8 9.0 0.035 0.0 SAH
EDO
HOH
 2.905
5.702
3.084
 O
N
NE1
 N
O1
O
6mbp 1 Q9H9B1 100.0 0.0 X-RAY
 2019-02-27 TRP A:133 A:1107 16.0 0.063 E -81.8 152.1 16.0 0.063 0.0 SAH
HOH
 2.838
2.845
 N
NE1
 O
O
TRP B:133 B:1107 16.0 0.063 E -81.4 147.3 16.0 0.063 0.0 SAH
HOH
 2.767
3.812
 O
CD1
 N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9h9b1-f1 1 Q9H9B1 100.0 0.0 TRP A:1138 A:1138 28.0 0.11 E -85.0 145.4