Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 90343723 . C A CCDS6675.1:NM_001257971.1:c.620aCa>aAa_NP_001244900.1:p.207T>K Homo sapiens cathepsin L (CTSL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1cs8 1 P07711 99.37 0.0 X-RAY
 1999-08-23 THR A:190 A:94 63.0 0.45 S -167.8 147.1 63.0 0.45 0.0 HOH
 2.305
 OG1
 H1
6jd8 1 P07711 98.42 0.0 X-RAY
 2020-02-05 THR A:234 A:190 73.0 0.521 S -145.1 151.3 73.0 0.521 0.0 EOH
HOH
 9.090
5.740
 C
O
 HO
O
6jd0 1 P07711 97.47 0.0 X-RAY
 2020-02-05 THR A:234 A:190 67.0 0.479 S -157.9 156.6 67.0 0.479 0.0 PO4
POL
PGE
PGE
EOH
HOH
 7.066
9.476
9.403
5.071
7.410
3.125
 HA
H
HG22
HG22
O
HA
 O4
H31
H1
H6
HO
O
1cjl 1 P07711 98.4 0.0 X-RAY
 1997-08-12 THR A:186 A:94 58.0 0.414 S -158.6 167.9 58.0 0.414 0.0 HOH
 4.992
 O
 H2
3hwn 1 P07711 99.61 0.0 X-RAY
 2009-09-15 THR A:132 A:94 57.0 0.407 S -147.8 143.9 57.0 0.407 0.0 HOH
 3.765
 OG1
 O
THR B:132 B:94 65.0 0.464 S -149.1 147.8 NA NA NA
THR C:132 C:94 59.0 0.421 S -125.3 159.7 NA NA NA
THR D:132 D:94 50.0 0.357 S -164.7 152.6 NA NA NA
3of8 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 THR A:95 A:95 75.0 0.536 S -142.5 168.3 75.0 0.536 0.0 HOH
 6.915
 N
 O
3of9 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 THR A:95 A:95 67.0 0.479 S -148.6 179.2 67.0 0.479 0.0
2xu3 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 THR A:94 A:94 66.0 0.471 S -153.4 146.9 66.0 0.471 0.0 HOH
 2.882
 HA
 O
2xu4 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 THR A:94 A:94 79.0 0.564 S -154.9 161.7 79.0 0.564 0.0 GOL
HOH
 6.687
3.058
 N
HA
 H12
O
2xu5 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 THR A:94 A:94 63.0 0.45 S -154.4 148.7 63.0 0.45 0.0 HOH
 5.304
 O
 O
2yj2 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 THR A:94 A:94 66.0 0.471 S -142.2 149.7 66.0 0.471 0.0 HOH
 2.881
 HA
 O
2yj8 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 THR A:94 A:94 66.0 0.471 S -145.0 145.3 66.0 0.471 0.0 HOH
 2.956
 HA
 O
2yj9 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 THR A:94 A:94 65.0 0.464 S -141.3 151.8 65.0 0.464 0.0 HOH
 2.891
 HA
 O
2yjb 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 THR A:94 A:94 54.0 0.386 S -140.9 173.2 54.0 0.386 0.0 HOH
 5.974
 O
 O
2yjc 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 THR A:94 A:94 66.0 0.471 S -145.8 151.4 66.0 0.471 0.0 HOH
 2.795
 HA
 O
3bc3 1 P07711 100.0 3e-166 X-RAY
 2008-03-18 THR A:94 A:94 64.0 0.457 S -160.7 143.2 64.0 0.457 0.0 HOH
 3.781
 OG1
 O
THR B:94 B:94 65.0 0.464 S -163.1 139.0 NA NA NA
3h89 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 THR A:94 A:94 67.0 0.479 S -154.0 146.0 67.0 0.479 0.0 HOH
 5.467
 C
 O
THR B:94 B:94 68.0 0.486 S -153.6 144.5 NA NA NA
THR C:94 C:94 66.0 0.471 S -163.8 134.4 NA NA NA
THR D:94 D:94 64.0 0.457 S -151.8 151.7 NA NA NA
THR E:94 E:94 64.0 0.457 S -167.6 145.9 NA NA NA
THR F:94 F:94 67.0 0.479 S -167.2 150.9 NA NA NA
3h8b 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 THR A:94 A:94 66.0 0.471 S -160.8 144.2 66.0 0.471 0.0 NSY
HOH
 9.982
3.475
 N
OG1
 C6
O
THR B:94 B:94 68.0 0.486 S -161.0 143.6 NA NA NA
THR C:94 C:94 66.0 0.471 S -164.0 146.9 NA NA NA
THR D:94 D:94 62.0 0.443 S -159.7 149.8 NA NA NA
THR E:94 E:94 68.0 0.486 S -173.7 142.1 NA NA NA
THR F:94 F:94 66.0 0.471 S -171.6 145.4 NA NA NA
3h8c 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 THR A:94 A:94 64.0 0.457 S -168.9 151.2 64.0 0.457 0.0 HOH
 2.635
 OG1
 O
THR B:94 B:94 68.0 0.486 S -152.6 151.0 NA NA NA
4axl 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 THR A:94 A:94 68.0 0.486 S -159.6 144.0 68.0 0.486 0.0 HOH
 3.820
 OG1
 O
4axm 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 THR A:94 A:94 71.0 0.507 S -106.2 -168.9 71.0 0.507 0.0 HOH
 6.669
 N
 O
THR B:94 B:94 66.0 0.471 S -143.5 148.4 NA NA NA
THR C:94 F:94 67.0 0.479 S -145.8 155.7 NA NA NA
THR D:94 I:94 65.0 0.464 S -139.1 162.0 NA NA NA
THR E:94 L:94 70.0 0.5 S -156.6 155.4 NA NA NA
THR F:94 O:94 81.0 0.579 S -137.7 151.3 NA NA NA
5f02 1 P07711 100.0 3e-166 X-RAY
 2016-02-24 THR A:94 A:94 67.0 0.479 S -147.2 147.2 67.0 0.479 0.0 HOH
 2.774
 HA
 O
5mae 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 THR A:94 A:94 67.0 0.479 S -140.4 151.9 67.0 0.479 0.0 HOH
 3.684
 CG2
 O
5maj 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 THR A:94 A:94 68.0 0.486 S -142.6 150.8 68.0 0.486 0.0 HOH
 3.269
 O
 O
5mqy 1 P07711 100.0 3e-166 X-RAY
 2017-03-22 THR A:94 A:94 67.0 0.479 S -147.1 146.7 67.0 0.479 0.0 EDO
HOH
 8.507
3.664
 C
CA
 O2
O
6ezp 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 THR A:94 A:94 65.0 0.464 S -151.5 154.6 65.0 0.464 0.0 GOL
HOH
 6.645
2.824
 N
O
 C3
O
6ezx 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 THR A:94 A:94 73.0 0.521 S -140.7 154.7 73.0 0.521 0.0 HOH
 4.009
 CG2
 O
THR B:94 B:94 78.0 0.557 S -152.1 155.3 78.0 0.557 0.0 HOH
 6.152
 O
 O
6f06 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 THR A:94 A:94 66.0 0.471 S -150.8 -172.1 66.0 0.471 0.0 ZN
HOH
 5.597
3.671
 OG1
CB
 ZN
O
THR B:94 B:94 68.0 0.486 S -132.3 -170.6 NA NA NA
2nqd 2 P07711 99.55 1e-165 X-RAY
 2007-07-24 THR B:95 B:94 62.0 0.443 S -143.0 155.0 62.0 0.443 0.0 HOH
 2.833
 OG1
 O
2xu1 1 P07711 99.55 2e-165 X-RAY
 2011-01-12 THR A:94 A:94 65.0 0.464 S -155.9 149.2 65.0 0.464 0.0 HOH
 3.338
 OG1
 O
THR B:94 B:94 87.0 0.621 S -156.3 153.8 NA NA NA
THR C:94 C:94 77.0 0.55 S -156.7 152.6 NA NA NA
THR D:94 D:94 81.0 0.579 S -156.2 150.4 NA NA NA
3hha 1 P07711 99.55 2e-165 X-RAY
 2009-06-23 THR A:94 A:94 75.0 0.536 S -159.5 150.4 75.0 0.536 0.0 HOH
 2.709
 OG1
 O
THR B:94 B:94 65.0 0.464 S -157.7 151.2 NA NA NA
THR C:94 C:94 72.0 0.514 S -157.9 146.4 NA NA NA
THR D:94 D:94 67.0 0.479 S -157.7 147.4 NA NA NA
3iv2 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 THR A:94 A:94 64.0 0.457 S -156.1 150.9 64.0 0.457 0.0 HOH
 5.505
 C
 O
THR B:94 B:94 68.0 0.486 S -164.8 152.6 68.0 0.486 0.0 HOH
 5.002
 N
 O
3k24 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 THR A:94 A:94 70.0 0.5 S -153.5 157.8 70.0 0.5 0.0 HOH
 5.135
 CG2
 O
THR B:94 B:94 68.0 0.486 S -132.7 159.5 NA NA NA
3kse 1 P07711 99.09 8e-165 X-RAY
 2010-12-01 THR A:94 A:94 74.0 0.529 S -153.7 147.8 73.0 0.521 0.008 D:P01040:0.007
 HOH
 5.574
 O
 O
THR B:94 B:94 73.0 0.521 S -155.4 147.9 NA NA NA
THR C:94 C:94 74.0 0.529 S -153.1 148.7 NA NA NA
2vhs 1 P07711 91.82 1e-145 X-RAY
 2008-03-11 THR A:94 A:94 62.0 0.443 S -154.0 153.6 62.0 0.443 0.0 HOH
 3.174
 OG1
 O
THR B:94 B:94 73.0 0.521 S -160.8 145.4 73.0 0.521 0.0 HOH
 2.576
 OG1
 O
THR C:94 C:94 72.0 0.514 S -153.5 151.7 72.0 0.514 0.0 HOH
 2.786
 OG1
 O
THR D:94 D:94 61.0 0.436 S -154.9 152.3 61.0 0.436 0.0 HOH
 3.643
 CA
 O
1icf 1 P07711 100.0 1e-129 X-RAY
 2000-01-12 THR A:94 A:94 71.0 0.507 S -156.4 154.8 71.0 0.507 0.0 HOH
 3.271
 OG1
 O
THR C:94 C:94 73.0 0.521 S -153.4 155.7 NA NA NA
1mhw 1 P07711 100.0 1e-129 X-RAY
 2002-12-11 THR A:94 A:94 70.0 0.5 S -159.3 145.9 70.0 0.5 0.0 HOH
 3.386
 OG1
 O
THR C:94 B:94 69.0 0.493 S -158.0 149.5 NA NA NA
5i4h 1 P07711 99.06 5e-73 X-RAY
 2016-04-13 THR A:95 A:94 69.0 0.493 S -158.5 149.1 69.0 0.493 0.0 SO4
HOH
 1.993
2.621
 HG1
HA
 O4
H1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07711-f1 1 P07711 100.0 0.0 THR A:207 A:207 69.0 0.493 S -148.1 154.2