Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 90344527 . A C CCDS6675.1:NM_001257971.1:c.661Aat>Cat_NP_001244900.1:p.221N>H Homo sapiens cathepsin L (CTSL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1cs8 1 P07711 99.37 0.0 X-RAY
 1999-08-23 ASN A:204 A:108 73.0 0.456 -159.0 159.9 73.0 0.456 0.0 HOH
 5.641
 H
 H2
6jd8 1 P07711 98.42 0.0 X-RAY
 2020-02-05 ASN A:248 A:204 65.0 0.406 -159.8 168.0 65.0 0.406 0.0 PEG
HOH
 2.298
2.551
 HB2
HA
 H32
O
6jd0 1 P07711 97.47 0.0 X-RAY
 2020-02-05 ASN A:248 A:204 62.0 0.388 -146.7 163.3 62.0 0.388 0.0 GOL
GOL
HOH
 3.697
2.198
2.583
 HD21
HD22
HA
 O1
O2
O
1cjl 1 P07711 98.4 0.0 X-RAY
 1997-08-12 ASN A:200 A:108 111.0 0.694 -78.3 -18.9 111.0 0.694 0.0 HOH
 2.473
 O
 H1
3hwn 1 P07711 99.61 0.0 X-RAY
 2009-09-15 ASN A:146 A:108 70.0 0.438 -157.9 166.0 70.0 0.438 0.0 HOH
 7.066
 ND2
 O
ASN B:146 B:108 80.0 0.5 -151.0 166.9 NA NA NA
ASN C:146 C:108 71.0 0.444 -177.2 162.7 NA NA NA
ASN D:146 D:108 82.0 0.512 -148.1 169.4 NA NA NA
3of8 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 ASN A:109 A:109 66.0 0.412 -166.3 163.8 66.0 0.412 0.0 HOH
 7.334
 N
 O
3of9 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 ASN A:109 A:109 69.0 0.431 -147.7 166.0 69.0 0.431 0.0
2xu3 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 ASN A:108 A:108 56.0 0.35 -147.2 165.2 56.0 0.35 0.0 HOH
 1.371
 OD1
 O
2xu4 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 ASN A:108 A:108 83.0 0.519 -149.4 161.7 83.0 0.519 0.0 HOH
 2.526
 HB3
 O
2xu5 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 ASN A:108 A:108 62.0 0.388 -154.0 165.3 62.0 0.388 0.0 HOH
 2.716
 OD1
 O
2yj2 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 ASN A:108 A:108 76.0 0.475 -148.5 160.9 76.0 0.475 0.0 HOH
 2.212
 OD1
 O
2yj8 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 ASN A:108 A:108 77.0 0.481 -144.9 166.3 77.0 0.481 0.0 HOH
 2.102
 HB2
 O
2yj9 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 ASN A:108 A:108 71.0 0.444 -147.8 165.6 71.0 0.444 0.0 HOH
 0.765
 ND2
 O
2yjb 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 ASN A:108 A:108 80.0 0.5 -152.0 161.6 80.0 0.5 0.0 HOH
 2.506
 HB2
 O
2yjc 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 ASN A:108 A:108 74.0 0.463 -147.8 163.8 74.0 0.463 0.0 HOH
 2.113
 HB2
 O
3bc3 1 P07711 100.0 3e-166 X-RAY
 2008-03-18 ASN A:108 A:108 61.0 0.381 -172.2 157.0 61.0 0.381 0.0 HOH
 2.688
 O
 O
ASN B:108 B:108 61.0 0.381 -160.2 170.7 NA NA NA
3h89 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 ASN A:108 A:108 69.0 0.431 -170.0 164.4 69.0 0.431 0.0 HOH
 5.411
 OD1
 O
ASN B:108 B:108 67.0 0.419 -170.8 165.4 NA NA NA
ASN C:108 C:108 62.0 0.388 -175.0 -177.4 NA NA NA
ASN D:108 D:108 72.0 0.45 -154.3 167.8 NA NA NA
ASN E:108 E:108 68.0 0.425 -177.5 160.6 NA NA NA
ASN F:108 F:108 75.0 0.469 -164.3 141.1 NA NA NA
3h8b 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 ASN A:108 A:108 71.0 0.444 -159.0 177.7 71.0 0.444 0.0 HOH
 3.479
 N
 O
ASN B:108 B:108 70.0 0.438 -158.7 178.2 NA NA NA
ASN C:108 C:108 73.0 0.456 -157.4 159.3 NA NA NA
ASN D:108 D:108 71.0 0.444 -157.3 163.2 NA NA NA
ASN E:108 E:108 66.0 0.412 -171.0 164.3 NA NA NA
ASN F:108 F:108 70.0 0.438 -165.2 168.1 NA NA NA
3h8c 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 ASN A:108 A:108 60.0 0.375 -174.8 153.9 60.0 0.375 0.0 HOH
 2.925
 O
 O
ASN B:108 B:108 56.0 0.35 -171.4 162.2 NA NA NA
4axl 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 ASN A:108 A:108 59.0 0.369 -145.6 151.4 59.0 0.369 0.0 HOH
 6.119
 ND2
 O
4axm 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 ASN A:108 A:108 77.0 0.481 -152.2 152.4 77.0 0.481 0.0 HOH
 6.591
 ND2
 O
ASN B:108 B:108 78.0 0.487 -150.4 137.7 NA NA NA
ASN C:108 F:108 80.0 0.5 -127.1 161.2 NA NA NA
ASN D:108 I:108 82.0 0.512 -135.6 155.1 NA NA NA
ASN E:108 L:108 91.0 0.569 -103.6 159.8 NA NA NA
ASN F:108 O:108 70.0 0.438 -137.2 155.6 NA NA NA
5f02 1 P07711 100.0 3e-166 X-RAY
 2016-02-24 ASN A:108 A:108 75.0 0.469 -146.0 162.4 75.0 0.469 0.0 HOH
 2.284
 HB2
 O
5mae 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 ASN A:108 A:108 74.0 0.463 -151.2 165.4 74.0 0.463 0.0 HOH
 2.979
 O
 O
5maj 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 ASN A:108 A:108 74.0 0.463 -151.4 166.1 74.0 0.463 0.0 HOH
 3.008
 O
 O
5mqy 1 P07711 100.0 3e-166 X-RAY
 2017-03-22 ASN A:108 A:108 71.0 0.444 -150.7 167.6 71.0 0.444 0.0 HOH
 6.661
 N
 O
6ezp 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 ASN A:108 A:108 55.0 0.344 -144.7 162.4 55.0 0.344 0.0 HOH
 2.021
 ND2
 O
6ezx 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 ASN A:108 A:108 59.0 0.369 -151.0 165.6 51.0 0.319 0.05 B:P07711:0.05
 HOH
 7.045
 N
 O
ASN B:108 B:108 55.0 0.344 E -155.1 156.9 44.0 0.275 0.069 A:P07711:0.069
 HOH
 6.964
 N
 O
6f06 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 ASN A:108 A:108 72.0 0.45 -153.1 155.0 72.0 0.45 0.0 HOH
 3.208
 CB
 O
ASN B:108 B:108 63.0 0.394 -151.5 155.7 NA NA NA
2nqd 2 P07711 99.55 1e-165 X-RAY
 2007-07-24 ASN B:109 B:108 84.0 0.525 -147.6 167.5 84.0 0.525 0.0 HOH
 6.518
 N
 O
2xu1 1 P07711 99.55 2e-165 X-RAY
 2011-01-12 ASN A:108 A:108 72.0 0.45 -153.6 164.7 72.0 0.45 0.0 HOH
 2.663
 ND2
 O
ASN B:108 B:108 79.0 0.494 -149.0 155.8 NA NA NA
ASN C:108 C:108 82.0 0.512 -147.9 153.5 NA NA NA
ASN D:108 D:108 72.0 0.45 -150.4 160.5 NA NA NA
3hha 1 P07711 99.55 2e-165 X-RAY
 2009-06-23 ASN A:108 A:108 74.0 0.463 -155.9 161.9 74.0 0.463 0.0 HOH
 2.823
 O
 O
ASN B:108 B:108 73.0 0.456 -154.4 164.3 NA NA NA
ASN C:108 C:108 68.0 0.425 -147.9 163.8 NA NA NA
ASN D:108 D:108 79.0 0.494 -146.1 160.6 NA NA NA
3iv2 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 ASN A:108 A:108 84.0 0.525 -120.3 166.1 84.0 0.525 0.0 NAG
HOH
 1.435
3.024
 ND2
OD1
 C1
O
ASN B:108 B:108 89.0 0.556 -123.8 167.6 89.0 0.556 0.0 HOH
 3.593
 OD1
 O
3k24 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 ASN A:108 A:108 86.0 0.537 -137.4 160.8 86.0 0.537 0.0 NAG
 1.441
 ND2
 C1
ASN B:108 B:108 84.0 0.525 -126.5 163.2 NA NA NA
3kse 1 P07711 99.09 8e-165 X-RAY
 2010-12-01 ASN A:108 A:108 82.0 0.512 -170.5 160.9 82.0 0.512 0.0 HOH
 6.545
 N
 O
ASN B:108 B:108 84.0 0.525 -157.7 161.5 NA NA NA
ASN C:108 C:108 69.0 0.431 -159.7 160.0 NA NA NA
2vhs 1 P07711 91.82 1e-145 X-RAY
 2008-03-11 ASN A:108 A:108 47.0 0.294 -146.5 170.0 47.0 0.294 0.0 HOH
 2.741
 ND2
 O
ASN B:108 B:108 49.0 0.306 -149.4 166.6 49.0 0.306 0.0 HOH
 2.702
 OD1
 O
ASN C:108 C:108 49.0 0.306 -146.0 167.9 49.0 0.306 0.0 HOH
 2.674
 ND2
 O
ASN D:108 D:108 52.0 0.325 -143.9 169.5 52.0 0.325 0.0 HOH
 2.711
 ND2
 O
1icf 1 P07711 100.0 1e-129 X-RAY
 2000-01-12 ASN A:108 A:108 94.0 0.588 -163.1 130.9 83.0 0.519 0.069 B:P07711:0.069
 HOH
 2.768
 ND2
 O
ASN C:108 C:108 87.0 0.544 -156.2 142.1 NA NA NA
1mhw 1 P07711 100.0 1e-129 X-RAY
 2002-12-11 ASN A:108 A:108 74.0 0.463 -165.0 162.5 69.0 0.431 0.032 B:P07711:0.031
 HOH
 3.013
 ND2
 O
ASN C:108 B:108 84.0 0.525 -152.0 163.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07711-f1 1 P07711 100.0 0.0 ASN A:221 A:221 51.0 0.319 -134.8 155.1