Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr9 90345928 . G A CCDS6675.1:NM_001257971.1:c.908gGt>gAt_NP_001244900.1:p.303G>D Homo sapiens cathepsin L (CTSL), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1cs8 1 P07711 99.37 0.0 X-RAY
 1999-08-23 GLY A:286 A:190 7.0 0.093 81.7 171.0 7.0 0.093 0.0 HOH
 2.020
 O
 H1
6jd8 1 P07711 98.42 0.0 X-RAY
 2020-02-05 GLY A:330 A:286 9.0 0.12 83.9 169.0 9.0 0.12 0.0 EOH
EOH
EOH
EDO
PGE
HOH
 9.143
9.198
7.285
9.269
9.748
2.526
 HA3
HA2
HA2
HA2
H
HA3
 H23
H12
H23
H11
H12
O
6jd0 1 P07711 97.47 0.0 X-RAY
 2020-02-05 GLY A:330 A:286 8.0 0.107 T 73.7 173.3 8.0 0.107 0.0 GOL
GOL
NA
PO4
POL
POL
PGE
HOH
 9.464
9.838
2.693
2.683
4.942
9.946
6.022
2.794
 C
O
HA2
HA3
HA2
HA2
HA3
O
 O3
HO3
NA
O2
O
H12
H12
O
1cjl 1 P07711 98.4 0.0 X-RAY
 1997-08-12 GLY A:282 A:190 9.0 0.12 84.0 169.8 9.0 0.12 0.0 HOH
 2.721
 O
 O
3hwn 1 P07711 99.61 0.0 X-RAY
 2009-09-15 GLY A:228 A:190 5.0 0.067 81.4 160.1 5.0 0.067 0.0 HOH
 3.152
 O
 O
GLY B:228 B:190 11.0 0.147 61.1 153.1 NA NA NA
GLY C:228 C:190 9.0 0.12 T 67.6 170.0 NA NA NA
GLY D:228 D:190 13.0 0.173 84.0 163.9 NA NA NA
3of8 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 GLY A:191 A:191 5.0 0.067 79.8 169.7 5.0 0.067 0.0 I0Y
HOH
 9.990
2.631
 N
O
 C25
O
3of9 1 P07711 100.0 7e-167 X-RAY
 2010-12-08 GLY A:191 A:191 5.0 0.067 80.5 167.7 5.0 0.067 0.0
2xu3 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLY A:190 A:190 4.0 0.053 77.1 170.7 4.0 0.053 0.0 BTB
HOH
 4.824
2.106
 N
HA3
 O1
O
2xu4 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLY A:190 A:190 7.0 0.093 77.4 173.1 7.0 0.093 0.0 GOL
HOH
 6.614
2.689
 HA3
HA2
 O2
O
2xu5 1 P07711 100.0 3e-166 X-RAY
 2011-01-12 GLY A:190 A:190 7.0 0.093 69.0 170.7 7.0 0.093 0.0 FLC
HOH
 5.377
2.954
 N
O
 OA1
O
2yj2 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLY A:190 A:190 4.0 0.053 80.7 168.7 4.0 0.053 0.0 GOL
HOH
 4.855
2.729
 N
HA2
 O3
O
2yj8 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLY A:190 A:190 4.0 0.053 84.2 164.7 4.0 0.053 0.0 GOL
HOH
 5.149
2.589
 N
HA2
 H31
O
2yj9 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLY A:190 A:190 4.0 0.053 84.0 166.9 4.0 0.053 0.0 GOL
HOH
 4.931
2.657
 N
HA2
 O3
O
2yjb 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLY A:190 A:190 8.0 0.107 87.5 163.9 8.0 0.107 0.0 GOL
HOH
 5.612
2.778
 N
O
 HO1
O
2yjc 1 P07711 100.0 3e-166 X-RAY
 2011-11-23 GLY A:190 A:190 8.0 0.107 83.6 170.1 8.0 0.107 0.0 HOH
 2.791
 HA3
 O
3bc3 1 P07711 100.0 3e-166 X-RAY
 2008-03-18 GLY A:190 A:190 7.0 0.093 94.1 167.2 7.0 0.093 0.0 OPT
HOH
 6.659
2.821
 N
O
 C11
O
GLY B:190 B:190 8.0 0.107 89.8 158.8 NA NA NA
3h89 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLY A:190 A:190 9.0 0.12 80.4 165.9 9.0 0.12 0.0 NSX
HOH
 9.277
2.949
 N
O
 O3
O
GLY B:190 B:190 9.0 0.12 79.3 165.5 NA NA NA
GLY C:190 C:190 9.0 0.12 81.5 174.8 NA NA NA
GLY D:190 D:190 8.0 0.107 83.9 168.9 NA NA NA
GLY E:190 E:190 7.0 0.093 86.7 169.3 NA NA NA
GLY F:190 F:190 7.0 0.093 81.1 170.5 NA NA NA
3h8b 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLY A:190 A:190 7.0 0.093 83.8 168.1 7.0 0.093 0.0 NSY
HOH
 9.530
2.780
 N
O
 O3
O
GLY B:190 B:190 8.0 0.107 84.0 167.7 NA NA NA
GLY C:190 C:190 9.0 0.12 80.8 172.5 NA NA NA
GLY D:190 D:190 7.0 0.093 81.9 171.9 NA NA NA
GLY E:190 E:190 7.0 0.093 81.4 173.6 NA NA NA
GLY F:190 F:190 8.0 0.107 81.0 173.7 NA NA NA
3h8c 1 P07711 100.0 3e-166 X-RAY
 2009-10-20 GLY A:190 A:190 6.0 0.08 99.0 168.2 6.0 0.08 0.0 NSZ
HOH
 5.611
2.786
 N
O
 C13
O
GLY B:190 B:190 5.0 0.067 94.0 175.5 NA NA NA
4axl 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 GLY A:190 A:190 4.0 0.053 83.2 163.8 4.0 0.053 0.0 GOL
HOH
 3.696
2.798
 CA
O
 O3
O
4axm 1 P07711 100.0 3e-166 X-RAY
 2013-05-08 GLY A:190 A:190 4.0 0.053 84.4 165.6 4.0 0.053 0.0 GOL
HOH
 6.115
3.144
 N
O
 O3
O
GLY B:190 B:190 7.0 0.093 T 69.2 178.1 NA NA NA
GLY C:190 F:190 3.0 0.04 82.9 166.7 NA NA NA
GLY D:190 I:190 3.0 0.04 T 64.2 162.4 NA NA NA
GLY E:190 L:190 2.0 0.027 82.3 164.1 NA NA NA
GLY F:190 O:190 4.0 0.053 T 75.6 169.2 NA NA NA
5f02 1 P07711 100.0 3e-166 X-RAY
 2016-02-24 GLY A:190 A:190 8.0 0.107 81.9 170.5 8.0 0.107 0.0 GOL
HOH
 4.851
2.727
 N
HA2
 H11
O
5mae 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 GLY A:190 A:190 8.0 0.107 84.1 167.8 8.0 0.107 0.0 HOH
 2.865
 O
 O
5maj 1 P07711 100.0 3e-166 X-RAY
 2017-01-11 GLY A:190 A:190 8.0 0.107 79.2 165.9 8.0 0.107 0.0 HOH
 2.837
 O
 O
5mqy 1 P07711 100.0 3e-166 X-RAY
 2017-03-22 GLY A:190 A:190 8.0 0.107 76.2 168.0 8.0 0.107 0.0 EDO
HOH
 7.018
2.789
 CA
O
 O1
O
6ezp 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLY A:190 A:190 8.0 0.107 81.6 173.9 8.0 0.107 0.0 GOL
GOL
HOH
 5.726
7.782
2.847
 N
N
O
 C1
O1
O
6ezx 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLY A:190 A:190 5.0 0.067 77.1 177.4 5.0 0.067 0.0 HOH
 3.079
 O
 O
GLY B:190 B:190 4.0 0.053 73.5 172.3 4.0 0.053 0.0 HOH
 3.060
 O
 O
6f06 1 P07711 100.0 3e-166 X-RAY
 2018-04-11 GLY A:190 A:190 3.0 0.04 98.6 161.1 3.0 0.04 0.0 HOH
 2.983
 O
 O
GLY B:190 B:190 6.0 0.08 86.5 165.5 NA NA NA
2nqd 2 P07711 99.55 1e-165 X-RAY
 2007-07-24 GLY B:191 B:190 5.0 0.067 78.7 167.7 5.0 0.067 0.0 HOH
 2.804
 O
 O
2xu1 1 P07711 99.55 2e-165 X-RAY
 2011-01-12 GLY A:190 A:190 4.0 0.053 81.5 167.0 4.0 0.053 0.0 HOH
 2.832
 O
 O
GLY B:190 B:190 4.0 0.053 84.4 163.2 NA NA NA
GLY C:190 C:190 10.0 0.133 81.8 165.6 NA NA NA
GLY D:190 D:190 7.0 0.093 82.6 176.4 NA NA NA
3hha 1 P07711 99.55 2e-165 X-RAY
 2009-06-23 GLY A:190 A:190 4.0 0.053 79.7 168.0 4.0 0.053 0.0 PG4
HOH
 7.775
3.094
 N
O
 C5
O
GLY B:190 B:190 8.0 0.107 82.2 168.5 NA NA NA
GLY C:190 C:190 5.0 0.067 79.8 173.3 NA NA NA
GLY D:190 D:190 10.0 0.133 79.9 174.0 NA NA NA
3iv2 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 GLY A:190 A:190 6.0 0.08 76.2 173.5 6.0 0.08 0.0 GOL
SO4
HOH
 7.529
3.322
3.049
 N
CA
O
 O2
O2
O
GLY B:190 B:190 6.0 0.08 78.7 170.8 6.0 0.08 0.0 GOL
GOL
HOH
 8.877
3.336
3.528
 N
C
CA
 O3
O3
O
3k24 1 P07711 99.55 5e-165 X-RAY
 2010-03-23 GLY A:190 A:190 5.0 0.067 78.2 163.0 5.0 0.067 0.0 HOH
 7.876
 CA
 O
GLY B:190 B:190 4.0 0.053 68.5 169.5 NA NA NA
3kse 1 P07711 99.09 8e-165 X-RAY
 2010-12-01 GLY A:190 A:190 10.0 0.133 81.7 162.1 10.0 0.133 0.0 HOH
 2.838
 O
 O
GLY B:190 B:190 10.0 0.133 83.6 162.2 NA NA NA
GLY C:190 C:190 9.0 0.12 83.2 161.8 NA NA NA
2vhs 1 P07711 91.82 1e-145 X-RAY
 2008-03-11 GLY A:187 A:190 9.0 0.12 83.4 166.2 9.0 0.12 0.0 HOH
 2.795
 O
 O
GLY B:187 B:190 5.0 0.067 83.0 166.5 5.0 0.067 0.0 HOH
 2.808
 O
 O
GLY C:187 C:190 5.0 0.067 85.7 167.9 5.0 0.067 0.0 HOH
 2.832
 O
 O
GLY D:187 D:190 9.0 0.12 87.3 165.3 9.0 0.12 0.0 HOH
 2.838
 O
 O
5i4h 2 P07711 99.11 9e-78 X-RAY
 2016-04-13 GLY B:82 B:190 47.0 0.627 78.9 170.5 7.0 0.093 0.534 A:P07711:0.533
 SO4
HOH
 2.659
2.106
 HA3
O
 O4
H1
1icf 2 P07711 100.0 1e-23 X-RAY
 2000-01-12 GLY B:12 B:190 46.0 0.613 80.9 168.6 8.0 0.107 0.506 A:P07711:0.507
 HOH
 2.782
 O
 O
GLY D:12 D:190 47.0 0.627 80.9 165.5 NA NA NA
1mhw 2 P07711 100.0 1e-23 X-RAY
 2002-12-11 GLY B:12 C:190 50.0 0.667 88.1 164.7 9.0 0.12 0.547 A:P07711:0.547
 HOH
 2.809
 O
 O
GLY D:12 D:190 49.0 0.653 82.0 166.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07711-f1 1 P07711 100.0 0.0 GLY A:303 A:303 10.0 0.133 80.8 165.2