Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 135738541 | . | C | A | CCDS14659.1:NM_000074.2:c.373Cat>Aat_NP_000065.1:p.125H>N | Homo sapiens CD40 ligand (CD40LG), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1aly | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
1997-09-17 | HIS | A:10 | A:125 | 43.0 | 0.221 | E | -154.5 | 124.4 | 2.0 | 0.01 | 0.211 |
A:P29965:0.21 |
HOH |
1.995 |
NE2 |
H2 |
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1i9r | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2002-03-20 | HIS | A:10 | A:125 | 46.0 | 0.236 | E | -124.2 | 122.3 | 4.0 | 0.021 | 0.215 |
B:P29965:0.215 |
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HIS | B:10 | B:125 | 47.0 | 0.241 | E | -121.4 | 120.0 | 3.0 | 0.015 | 0.226 |
C:P29965:0.226 |
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HIS | C:10 | C:125 | 46.0 | 0.236 | E | -121.1 | 121.1 | 4.0 | 0.021 | 0.215 |
A:P29965:0.215 |
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6w9g | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2020-12-23 | HIS | A:10 | A:125 | 42.0 | 0.215 | E | -147.5 | 117.5 | 2.0 | 0.01 | 0.205 |
B:P29965:0.205 |
HOH |
2.917 |
NE2 |
O |
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HIS | B:10 | B:125 | 42.0 | 0.215 | E | -150.1 | 117.4 | 3.0 | 0.015 | 0.2 |
C:P29965:0.2 |
HOH |
2.872 |
NE2 |
O |
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HIS | C:10 | C:125 | 43.0 | 0.221 | E | -148.3 | 118.1 | 2.0 | 0.01 | 0.211 |
A:P29965:0.21 |
PEG HOH |
7.839 2.959 |
O NE2 |
C3 O |
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7sgm | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2022-02-02 | HIS | A:10 | A:125 | 41.0 | 0.21 | E | -146.6 | 118.1 | 3.0 | 0.015 | 0.195 |
B:P29965:0.195 |
HOH |
3.032 |
NE2 |
O |
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HIS | B:10 | B:125 | 42.0 | 0.215 | E | -148.8 | 117.4 | 2.0 | 0.01 | 0.205 |
C:P29965:0.205 |
HOH |
2.969 |
NE2 |
O |
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HIS | C:10 | C:125 | 43.0 | 0.221 | E | -145.0 | 118.1 | 3.0 | 0.015 | 0.206 |
A:P29965:0.205 |
HOH |
2.808 |
NE2 |
O |
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3qd6 | 1 | P29965 | 100.0 | 1e-106 |
X-RAY |
2011-02-02 | HIS | A:13 | A:125 | 45.0 | 0.231 | E | -138.8 | 114.0 | 0.0 | 0.0 | 0.231 |
B:P29965:0.231 |
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HIS | B:13 | B:125 | 46.0 | 0.236 | E | -137.4 | 115.2 | 1.0 | 0.005 | 0.231 |
C:P29965:0.231 |
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HIS | C:13 | C:125 | 46.0 | 0.236 | E | -138.0 | 118.1 | 0.0 | 0.0 | 0.236 |
A:P29965:0.236 |
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HIS | D:13 | D:125 | 46.0 | 0.236 | E | -139.0 | 113.6 | NA | NA | NA | |||||||||||||
HIS | E:13 | E:125 | 45.0 | 0.231 | E | -134.8 | 118.5 | NA | NA | NA | |||||||||||||
HIS | F:13 | F:125 | 45.0 | 0.231 | E | -136.2 | 117.4 | NA | NA | NA | |||||||||||||
6brb | 1 | P29965 | 100.0 | 5e-103 |
X-RAY |
2018-12-05 | HIS | A:6 | A:125 | 50.0 | 0.256 | E | -162.8 | 116.7 | 1.0 | 0.005 | 0.251 |
A:P29965:0.251 |
HOH |
5.365 |
NE2 |
O |
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3lkj | 1 | P29965 | 100.0 | 6e-102 |
X-RAY |
2011-02-02 | HIS | A:5 | A:125 | 49.0 | 0.251 | E | -144.9 | 120.4 | 1.0 | 0.005 | 0.246 |
B:P29965:0.246 |
HOH |
4.255 |
CE1 |
O |
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HIS | B:5 | B:125 | 49.0 | 0.251 | E | -140.8 | 123.9 | 1.0 | 0.005 | 0.246 |
C:P29965:0.246 |
LKJ HOH |
7.466 5.682 |
CE1 CE1 |
C28 O |
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HIS | C:5 | C:125 | 75.0 | 0.385 | E | -132.2 | 123.0 | 75.0 | 0.385 | 0.0 |
LKJ HOH |
2.766 2.824 |
CE1 O |
O6 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29965-f1 | 1 | P29965 | 100.0 | 0.0 | HIS | A:125 | A:125 | 39.0 | 0.2 | E | -143.7 | 119.2 |