Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 135741206 . T A CCDS14659.1:NM_000074.2:c.418Tgg>Agg_NP_000065.1:p.140W>R Homo sapiens CD40 ligand (CD40LG), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aly 1 P29965 100.0 9e-107 X-RAY
 1997-09-17 TRP A:25 A:140 0.0 0.0 E -134.9 161.1 0.0 0.0 0.0 HOH
 3.545
 CZ2
 H2
1i9r 1 P29965 100.0 9e-107 X-RAY
 2002-03-20 TRP A:25 A:140 7.0 0.027 E -151.6 146.8 7.0 0.027 0.0
TRP B:25 B:140 7.0 0.027 E -151.9 149.2 7.0 0.027 0.0
TRP C:25 C:140 6.0 0.024 E -153.6 150.8 6.0 0.024 0.0
6w9g 1 P29965 100.0 9e-107 X-RAY
 2020-12-23 TRP A:25 A:140 2.0 0.008 E -139.2 164.8 2.0 0.008 0.0 PEG
TMO
HOH
 9.511
6.643
2.695
 NE1
O
O
 C3
CAB
O
TRP B:25 B:140 8.0 0.031 E -142.3 165.8 8.0 0.031 0.0 PEG
TMO
HOH
 9.590
7.013
2.760
 NE1
O
O
 O4
OAE
O
TRP C:25 C:140 3.0 0.012 E -138.8 162.8 3.0 0.012 0.0 PEG
TMO
HOH
 9.759
6.885
2.699
 NE1
O
O
 O2
CAD
O
7sgm 1 P29965 100.0 9e-107 X-RAY
 2022-02-02 TRP A:25 A:140 5.0 0.02 E -140.5 162.3 5.0 0.02 0.0 PEG
HOH
 8.049
2.684
 O
O
 O4
O
TRP B:25 B:140 6.0 0.024 E -140.8 162.2 6.0 0.024 0.0 HOH
 3.020
 NE1
 O
TRP C:25 C:140 6.0 0.024 E -145.8 158.7 6.0 0.024 0.0 HOH
 2.902
 NE1
 O
3qd6 1 P29965 100.0 1e-106 X-RAY
 2011-02-02 TRP A:28 A:140 4.0 0.016 E -133.7 144.5 4.0 0.016 0.0
TRP B:28 B:140 4.0 0.016 E -134.0 137.6 4.0 0.016 0.0
TRP C:28 C:140 4.0 0.016 E -133.7 134.2 4.0 0.016 0.0
TRP D:28 D:140 5.0 0.02 E -134.8 138.3 NA NA NA
TRP E:28 E:140 4.0 0.016 E -129.3 131.8 NA NA NA
TRP F:28 F:140 4.0 0.016 E -136.5 148.0 NA NA NA
6brb 1 P29965 100.0 5e-103 X-RAY
 2018-12-05 TRP A:21 A:140 3.0 0.012 E -137.1 168.6 3.0 0.012 0.0 HOH
 5.116
 O
 O
3lkj 1 P29965 100.0 6e-102 X-RAY
 2011-02-02 TRP A:20 A:140 3.0 0.012 E -137.4 153.7 3.0 0.012 0.0 HOH
 2.919
 NE1
 O
TRP B:20 B:140 3.0 0.012 E -138.2 153.2 3.0 0.012 0.0 LKJ
HOH
 9.593
2.783
 CH2
NE1
 C27
O
TRP C:20 C:140 5.0 0.02 E -128.4 158.2 5.0 0.02 0.0 HOH
 4.791
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p29965-f1 1 P29965 100.0 0.0 TRP A:140 A:140 2.0 0.008 E -136.7 153.2