Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 135741449 | . | C | A | CCDS14659.1:NM_000074.2:c.661Caa>Aaa_NP_000065.1:p.221Q>K | Homo sapiens CD40 ligand (CD40LG), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1aly | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
1997-09-17 | GLN | A:106 | A:221 | 49.0 | 0.272 | E | -131.3 | 149.8 | 23.0 | 0.128 | 0.144 |
A:P29965:0.122 A:P29965:0.022 |
HOH |
2.208 |
HE22 |
H2 |
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1i9r | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2002-03-20 | GLN | A:106 | A:221 | 51.0 | 0.283 | E | -160.7 | 142.2 | 9.0 | 0.05 | 0.233 |
C:P29965:0.056 B:P29965:0.194 |
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GLN | B:106 | B:221 | 51.0 | 0.283 | E | -163.4 | 138.5 | 10.0 | 0.056 | 0.227 |
C:P29965:0.189 A:P29965:0.056 |
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GLN | C:106 | C:221 | 52.0 | 0.289 | E | -157.8 | 140.4 | 10.0 | 0.056 | 0.233 |
A:P29965:0.194 B:P29965:0.056 |
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6w9g | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2020-12-23 | GLN | A:106 | A:221 | 58.0 | 0.322 | E | -142.5 | 154.0 | 8.0 | 0.044 | 0.278 |
C:P29965:0.017 B:P29965:0.261 |
TRS TMO HOH |
3.540 8.159 2.964 |
NE2 N NE2 |
N OAE O |
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GLN | B:106 | B:221 | 86.0 | 0.478 | E | -142.4 | 153.0 | 12.0 | 0.067 | 0.411 |
C:P29965:0.378 A:P29965:0.056 |
TMO HOH |
7.887 5.902 |
N N |
CAA O |
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GLN | C:106 | C:221 | 60.0 | 0.333 | E | -142.4 | 153.4 | 5.0 | 0.028 | 0.305 |
A:P29965:0.306 B:P29965:0.006 |
TRS TMO HOH |
3.519 8.106 3.021 |
NE2 N NE2 |
N CAD O |
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7sgm | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2022-02-02 | GLN | A:106 | A:221 | 66.0 | 0.367 | E | -141.1 | 155.6 | 8.0 | 0.044 | 0.323 |
C:P29965:0.011 B:P29965:0.311 |
HOH |
2.891 |
NE2 |
O |
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GLN | B:106 | B:221 | 63.0 | 0.35 | E | -132.2 | 154.4 | 7.0 | 0.039 | 0.311 |
C:P29965:0.267 A:P29965:0.039 |
HOH |
3.009 |
OE1 |
O |
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GLN | C:106 | C:221 | 70.0 | 0.389 | E | -145.3 | 150.3 | 7.0 | 0.039 | 0.35 |
A:P29965:0.35 |
HOH |
3.591 |
CG |
O |
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3qd6 | 1 | P29965 | 100.0 | 1e-106 |
X-RAY |
2011-02-02 | GLN | A:109 | A:221 | 50.0 | 0.278 | E | -141.5 | 140.2 | 12.0 | 0.067 | 0.211 |
C:P29965:0.006 B:P29965:0.206 |
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GLN | B:109 | B:221 | 54.0 | 0.3 | E | -149.7 | 137.7 | 10.0 | 0.056 | 0.244 |
C:P29965:0.228 A:P29965:0.017 |
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GLN | C:109 | C:221 | 55.0 | 0.306 | E | -166.1 | 138.3 | 8.0 | 0.044 | 0.262 |
A:P29965:0.244 B:P29965:0.017 |
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GLN | D:109 | D:221 | 58.0 | 0.322 | -180.0 | 135.2 | NA | NA | NA | ||||||||||||||
GLN | E:109 | E:221 | 55.0 | 0.306 | E | -146.5 | 138.0 | NA | NA | NA | |||||||||||||
GLN | F:109 | F:221 | 62.0 | 0.344 | E | -168.9 | 142.8 | NA | NA | NA | |||||||||||||
6brb | 1 | P29965 | 100.0 | 5e-103 |
X-RAY |
2018-12-05 | GLN | A:102 | A:221 | 53.0 | 0.294 | E | -154.8 | 154.9 | 21.0 | 0.117 | 0.177 |
A:P29965:0.028 A:P29965:0.15 |
HOH |
7.479 |
NE2 |
O |
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3lkj | 1 | P29965 | 100.0 | 6e-102 |
X-RAY |
2011-02-02 | GLN | A:101 | A:221 | 96.0 | 0.533 | E | -136.2 | 144.6 | 26.0 | 0.144 | 0.389 |
B:P29965:0.389 |
HOH |
4.829 |
OE1 |
O |
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GLN | B:101 | B:221 | 88.0 | 0.489 | E | -141.3 | 140.3 | 17.0 | 0.094 | 0.395 |
C:P29965:0.394 |
HOH |
6.469 |
NE2 |
O |
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GLN | C:101 | C:221 | 70.0 | 0.389 | E | -137.9 | 179.3 | 66.0 | 0.367 | 0.022 |
A:P29965:0.022 |
HOH |
5.522 |
CA |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29965-f1 | 1 | P29965 | 100.0 | 0.0 | GLN | A:221 | A:221 | 46.0 | 0.256 | E | -141.5 | 151.5 |