Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 135741462 | . | T | A | CCDS14659.1:NM_000074.2:c.674tTg>tAg_NP_000065.1:p.225L>* | Homo sapiens CD40 ligand (CD40LG), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1aly | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
1997-09-17 | LEU | A:110 | A:225 | 8.0 | 0.047 | E | -113.7 | 136.1 | 0.0 | 0.0 | 0.047 |
A:P29965:0.047 |
HOH |
4.790 |
N |
H2 |
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1i9r | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2002-03-20 | LEU | A:110 | A:225 | 13.0 | 0.076 | E | -143.9 | 124.7 | 1.0 | 0.006 | 0.07 |
C:P29965:0.071 |
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LEU | B:110 | B:225 | 12.0 | 0.071 | E | -139.7 | 122.0 | 2.0 | 0.012 | 0.059 |
A:P29965:0.059 |
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LEU | C:110 | C:225 | 11.0 | 0.065 | E | -139.0 | 124.7 | 2.0 | 0.012 | 0.053 |
B:P29965:0.053 |
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6w9g | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2020-12-23 | LEU | A:110 | A:225 | 17.0 | 0.1 | E | -129.7 | 141.1 | 3.0 | 0.018 | 0.082 |
C:P29965:0.082 |
HOH |
3.356 |
CA |
O |
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LEU | B:110 | B:225 | 13.0 | 0.076 | E | -123.6 | 144.8 | 2.0 | 0.012 | 0.064 |
A:P29965:0.065 |
NAG HOH |
9.107 4.188 |
CD1 CD2 |
O7 O |
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LEU | C:110 | C:225 | 15.0 | 0.088 | E | -126.5 | 144.0 | 2.0 | 0.012 | 0.076 |
B:P29965:0.076 |
HOH |
4.855 |
O |
O |
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7sgm | 1 | P29965 | 100.0 | 9e-107 |
X-RAY |
2022-02-02 | LEU | A:110 | A:225 | 18.0 | 0.106 | E | -127.4 | 143.7 | 2.0 | 0.012 | 0.094 |
C:P29965:0.094 |
HOH |
3.753 |
CD2 |
O |
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LEU | B:110 | B:225 | 15.0 | 0.088 | E | -123.5 | 145.5 | 4.0 | 0.024 | 0.064 |
A:P29965:0.065 |
HOH |
4.113 |
CD2 |
O |
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LEU | C:110 | C:225 | 13.0 | 0.076 | E | -121.6 | 143.1 | 1.0 | 0.006 | 0.07 |
B:P29965:0.071 |
HOH |
4.110 |
CD1 |
O |
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3qd6 | 1 | P29965 | 100.0 | 1e-106 |
X-RAY |
2011-02-02 | LEU | A:113 | A:225 | 8.0 | 0.047 | E | -122.3 | 145.9 | 1.0 | 0.006 | 0.041 |
C:P29965:0.041 |
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LEU | B:113 | B:225 | 7.0 | 0.041 | E | -124.5 | 145.5 | 1.0 | 0.006 | 0.035 |
A:P29965:0.035 |
NAG |
9.691 |
CD2 |
O7 |
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LEU | C:113 | C:225 | 6.0 | 0.035 | E | -125.5 | 145.0 | 1.0 | 0.006 | 0.029 |
B:P29965:0.029 |
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LEU | D:113 | D:225 | 7.0 | 0.041 | E | -124.3 | 143.8 | NA | NA | NA | |||||||||||||
LEU | E:113 | E:225 | 8.0 | 0.047 | E | -125.3 | 145.7 | NA | NA | NA | |||||||||||||
LEU | F:113 | F:225 | 7.0 | 0.041 | E | -119.6 | 145.5 | NA | NA | NA | |||||||||||||
6brb | 1 | P29965 | 100.0 | 5e-103 |
X-RAY |
2018-12-05 | LEU | A:106 | A:225 | 11.0 | 0.065 | E | -109.5 | 140.1 | 2.0 | 0.012 | 0.053 |
A:P29965:0.053 |
NAG HOH |
9.526 9.251 |
CD1 CD2 |
C8 O |
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3lkj | 1 | P29965 | 100.0 | 6e-102 |
X-RAY |
2011-02-02 | LEU | A:105 | A:225 | 9.0 | 0.053 | E | -128.9 | 141.5 | 9.0 | 0.053 | 0.0 |
NAG LKJ HOH |
9.961 6.802 4.619 |
CD1 O N |
C1 C21 O |
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LEU | B:105 | B:225 | 13.0 | 0.076 | E | -125.8 | 131.7 | 8.0 | 0.047 | 0.029 |
A:P29965:0.029 |
NAG LKJ HOH |
8.167 3.478 6.131 |
CD1 N C |
C8 C26 O |
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LEU | C:105 | C:225 | 13.0 | 0.076 | E | -118.7 | 142.2 | 6.0 | 0.035 | 0.041 |
B:P29965:0.041 |
LKJ NAG HOH |
3.199 8.557 4.809 |
O CD1 N |
C18 C8 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29965-f1 | 1 | P29965 | 100.0 | 0.0 | LEU | A:225 | A:225 | 12.0 | 0.071 | E | -117.9 | 135.3 |