Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 153791119 | . | C | A | CCDS48196.1:NM_001099856.2:c.1067gCc>gAc_NP_001093326.2:p.356A>D | Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3jsv | 3 | O88522 | 89.36 | 2e-48 |
X-RAY |
2009-10-27 | ALA | C:32 | C:281 | 36.0 | 0.313 | H | -61.4 | -24.0 | 13.0 | 0.113 | 0.2 |
D:O88522:0.2 |
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ALA | D:32 | D:281 | 34.0 | 0.296 | H | -70.2 | -31.6 | 22.0 | 0.191 | 0.105 |
C:O88522:0.104 |
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3fx0 | 1 | Q9Y6K9 | 97.53 | 3e-46 |
X-RAY |
2009-04-07 | ALA | A:47 | A:288 | 48.0 | 0.417 | H | -96.6 | -20.1 | 18.0 | 0.157 | 0.26 |
B:Q9Y6K9:0.261 |
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ALA | B:47 | B:1288 | 46.0 | 0.4 | T | -116.0 | -25.5 | 30.0 | 0.261 | 0.139 |
A:Q9Y6K9:0.139 |
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4owf | 1 | O88522 | 90.0 | 5e-46 |
X-RAY |
2014-02-12 | ALA | A:32 | A:281 | 38.0 | 0.33 | H | -55.7 | -39.5 | 13.0 | 0.113 | 0.217 |
B:O88522:0.217 |
HOH |
3.340 |
CB |
O |
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ALA | B:32 | B:281 | 50.0 | 0.435 | H | -67.9 | -31.7 | 32.0 | 0.278 | 0.157 |
A:O88522:0.157 |
HOH |
2.862 |
O |
O |
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3f89 | 1 | O88522 | 88.89 | 1e-45 |
X-RAY |
2009-03-24 | ALA | A:34 | A:281 | 38.0 | 0.33 | H | -50.0 | -31.3 | 29.0 | 0.252 | 0.078 |
B:O88522:0.078 |
HOH |
3.399 |
CB |
O |
|
ALA | B:34 | B:281 | 50.0 | 0.435 | H | -69.5 | -32.7 | 18.0 | 0.157 | 0.278 |
A:O88522:0.278 |
HOH |
3.501 |
C |
O |
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2v4h | 1 | O88522 | 90.91 | 1e-44 |
X-RAY |
2009-11-03 | ALA | A:54 | A:281 | 47.0 | 0.409 | H | -44.3 | -24.3 | 16.0 | 0.139 | 0.27 |
B:O88522:0.27 |
HOH |
3.483 |
N |
O |
|
ALA | B:54 | B:281 | 54.0 | 0.47 | H | -55.6 | -33.4 | 21.0 | 0.183 | 0.287 |
A:O88522:0.287 |
HOH |
3.398 |
CB |
O |
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2zvo | 2 | O88522 | 87.78 | 2e-44 |
X-RAY |
2009-03-24 | ALA | C:34 | B:281 | 60.0 | 0.522 | H | -70.3 | -30.2 | 34.0 | 0.296 | 0.226 |
D:O88522:0.226 |
HOH |
2.391 |
O |
O |
|
ALA | D:34 | D:281 | 54.0 | 0.47 | H | -56.7 | -40.9 | 38.0 | 0.33 | 0.14 |
C:O88522:0.139 |
HOH |
3.245 |
CB |
O |
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2zvn | 2 | O88522 | 91.76 | 4e-43 |
X-RAY |
2009-03-24 | ALA | C:31 | B:281 | 50.0 | 0.435 | H | -64.4 | -41.9 | 23.0 | 0.2 | 0.235 |
D:O88522:0.235 |
HOH |
4.540 |
N |
O |
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ALA | D:31 | D:281 | 31.0 | 0.27 | H | -49.5 | -43.2 | 18.0 | 0.157 | 0.113 |
C:O88522:0.113 |
HOH |
7.317 |
CB |
O |
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ALA | G:31 | F:281 | 50.0 | 0.435 | H | -76.0 | -36.2 | NA | NA | NA | |||||||||||||
ALA | H:31 | H:281 | 22.0 | 0.191 | H | -66.3 | -29.6 | NA | NA | NA | |||||||||||||
4bwn | 1 | Q9Y6K9 | 94.68 | 2e-37 |
X-RAY |
2014-07-23 | ALA | A:54 | A:288 | 45.0 | 0.391 | H | -55.4 | -40.7 | 23.0 | 0.2 | 0.191 |
B:Q9Y6K9:0.191 |
HOH |
3.854 |
CA |
O |
|
ALA | B:54 | B:288 | 39.0 | 0.339 | H | -57.1 | -38.8 | 26.0 | 0.226 | 0.113 |
A:Q9Y6K9:0.113 |
HOH |
3.989 |
CA |
O |
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6xx0 | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-02-03 | ALA | A:33 | A:288 | 51.0 | 0.443 | H | -66.6 | -28.2 | 33.0 | 0.287 | 0.156 |
B:D3DWY0:0.157 |
HOH |
3.170 |
CB |
O |
|
ALA | B:33 | B:288 | 54.0 | 0.47 | H | -79.9 | -25.4 | 20.0 | 0.174 | 0.296 |
A:D3DWY0:0.296 |
HOH |
3.329 |
CB |
O |
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6yek | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-03-03 | ALA | A:33 | A:288 | 50.0 | 0.435 | H | -51.4 | -34.1 | 32.0 | 0.278 | 0.157 |
B:D3DWY0:0.157 |
HOH |
2.509 |
O |
O |
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ALA | B:33 | B:288 | 58.0 | 0.504 | H | -53.5 | -29.0 | 26.0 | 0.226 | 0.278 |
A:D3DWY0:0.278 |
HOH |
6.260 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9y6k9-f1 | 1 | Q9Y6K9 | 100.0 | 0.0 | ALA | A:288 | A:288 | 56.0 | 0.487 | H | -64.5 | -39.9 |