Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 153791792 | . | G | A | CCDS48196.1:NM_001099856.2:c.1135Gac>Aac_NP_001093326.2:p.379D>N | Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3jsv | 3 | O88522 | 89.36 | 2e-48 |
X-RAY |
2009-10-27 | ASP | C:55 | C:304 | 92.0 | 0.613 | H | -63.7 | -36.6 | 1.0 | 0.007 | 0.606 |
A:P62988:0.58 D:O88522:0.113 |
HOH |
7.274 |
OD1 |
O |
|
ASP | D:55 | D:304 | 95.0 | 0.633 | H | -47.7 | -48.0 | 73.0 | 0.487 | 0.146 |
C:O88522:0.147 |
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3fx0 | 1 | Q9Y6K9 | 97.53 | 3e-46 |
X-RAY |
2009-04-07 | ASP | A:70 | A:311 | 91.0 | 0.607 | H | -63.5 | -38.5 | 66.0 | 0.44 | 0.167 |
B:Q9Y6K9:0.167 |
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ASP | B:70 | B:1311 | 93.0 | 0.62 | H | -63.2 | -40.5 | 67.0 | 0.447 | 0.173 |
A:Q9Y6K9:0.173 |
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4owf | 1 | O88522 | 90.0 | 5e-46 |
X-RAY |
2014-02-12 | ASP | A:55 | A:304 | 92.0 | 0.613 | H | -60.9 | -40.9 | 65.0 | 0.433 | 0.18 |
B:O88522:0.18 |
HOH |
2.767 |
O |
O |
|
ASP | B:55 | B:304 | 95.0 | 0.633 | H | -60.9 | -41.2 | 69.0 | 0.46 | 0.173 |
A:O88522:0.173 |
HOH |
6.362 |
N |
O |
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3f89 | 1 | O88522 | 88.89 | 1e-45 |
X-RAY |
2009-03-24 | ASP | A:57 | A:304 | 80.0 | 0.533 | H | -65.8 | -34.2 | 59.0 | 0.393 | 0.14 |
B:O88522:0.14 |
HOH |
2.920 |
OD1 |
O |
|
ASP | B:57 | B:304 | 84.0 | 0.56 | H | -60.7 | -45.0 | 59.0 | 0.393 | 0.167 |
A:O88522:0.167 |
HOH |
2.415 |
OD2 |
O |
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2v4h | 1 | O88522 | 90.91 | 1e-44 |
X-RAY |
2009-11-03 | ASP | A:77 | A:304 | 88.0 | 0.587 | H | -58.2 | -38.0 | 49.0 | 0.327 | 0.26 |
D:None:0.133 B:O88522:0.127 |
HOH |
4.091 |
N |
O |
|
ASP | B:77 | B:304 | 94.0 | 0.627 | H | -67.7 | -59.6 | 0.0 | 0.0 | 0.627 |
A:O88522:0.593 A:O88522:0.12 C:None:0.107 |
HOH |
6.671 |
O |
O |
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2zvo | 2 | O88522 | 87.78 | 2e-44 |
X-RAY |
2009-03-24 | ASP | C:57 | B:304 | 99.0 | 0.66 | H | -59.6 | -36.0 | 2.0 | 0.013 | 0.647 |
D:O88522:0.107 B:Q96C32:0.64 |
HOH |
3.353 |
OD2 |
O |
|
ASP | D:57 | D:304 | 98.0 | 0.653 | H | -58.3 | -39.3 | 1.0 | 0.007 | 0.646 |
A:Q96C32:0.633 C:O88522:0.107 |
HOH |
6.753 |
OD1 |
O |
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2zvn | 2 | O88522 | 91.76 | 4e-43 |
X-RAY |
2009-03-24 | ASP | C:54 | B:304 | 87.0 | 0.58 | H | -54.6 | -44.2 | 4.0 | 0.027 | 0.553 |
D:O88522:0.1 B:Q96C32:0.54 |
HOH |
6.770 |
OD2 |
O |
|
ASP | D:54 | D:304 | 97.0 | 0.647 | H | -67.3 | -33.0 | 0.0 | 0.0 | 0.647 |
A:Q96C32:0.633 C:O88522:0.127 |
HOH |
7.126 |
N |
O |
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ASP | G:54 | F:304 | 93.0 | 0.62 | H | -54.0 | -48.6 | NA | NA | NA | |||||||||||||
ASP | H:54 | H:304 | 97.0 | 0.647 | H | -65.1 | -24.3 | NA | NA | NA | |||||||||||||
4bwn | 1 | Q9Y6K9 | 94.68 | 2e-37 |
X-RAY |
2014-07-23 | ASP | A:77 | A:311 | 91.0 | 0.607 | H | -63.2 | -43.1 | 65.0 | 0.433 | 0.174 |
B:Q9Y6K9:0.173 |
HOH |
3.232 |
OD2 |
O |
|
ASP | B:77 | B:311 | 93.0 | 0.62 | H | -52.6 | -49.6 | 67.0 | 0.447 | 0.173 |
A:Q9Y6K9:0.173 |
HOH |
2.769 |
O |
O |
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6xx0 | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-02-03 | ASP | A:56 | A:311 | 90.0 | 0.6 | H | -61.8 | -52.5 | 25.0 | 0.167 | 0.433 |
C:None:0.347 B:D3DWY0:0.16 |
HOH |
2.610 |
OD2 |
O |
|
ASP | B:56 | B:311 | 86.0 | 0.573 | H | -68.0 | -49.1 | 0.0 | 0.0 | 0.573 |
D:None:0.533 A:D3DWY0:0.16 |
HOH |
4.995 |
N |
O |
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6yek | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-03-03 | ASP | A:56 | A:311 | 77.0 | 0.513 | H | -65.8 | -33.7 | 57.0 | 0.38 | 0.133 |
B:D3DWY0:0.133 |
HOH |
2.624 |
OD1 |
O |
|
ASP | B:56 | B:311 | 100.0 | 0.667 | H | -68.5 | -34.7 | 77.0 | 0.513 | 0.154 |
A:D3DWY0:0.153 |
HOH |
3.243 |
OD1 |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9y6k9-f1 | 1 | Q9Y6K9 | 100.0 | 0.0 | ASP | A:311 | A:311 | 93.0 | 0.62 | H | -60.7 | -44.7 |