Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 153791797 . C A CCDS48196.1:NM_001099856.2:c.1140ttC>ttA_NP_001093326.2:p.380F>L Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3jsv 3 O88522 89.36 2e-48 X-RAY
 2009-10-27 PHE C:56 C:305 123.0 0.586 H -62.0 -56.5 40.0 0.19 0.396 D:O88522:0.395
PHE D:56 D:305 109.0 0.519 H -51.0 -63.0 4.0 0.019 0.5 A:P62988:0.305
C:O88522:0.338
 HOH
 6.572
 CZ
 O
3fx0 1 Q9Y6K9 97.53 3e-46 X-RAY
 2009-04-07 PHE A:71 A:312 108.0 0.514 H -66.9 -42.8 25.0 0.119 0.395 B:Q9Y6K9:0.395
PHE B:71 B:1312 111.0 0.529 H -63.6 -48.3 24.0 0.114 0.415 A:Q9Y6K9:0.414
4owf 1 O88522 90.0 5e-46 X-RAY
 2014-02-12 PHE A:56 A:305 124.0 0.59 H -66.6 -42.3 35.0 0.167 0.423 B:O88522:0.424
 HOH
 4.163
 CE2
 O
PHE B:56 B:305 110.0 0.524 H -54.4 -49.5 22.0 0.105 0.419 A:O88522:0.419
 HOH
 3.819
 CE1
 O
3f89 1 O88522 88.89 1e-45 X-RAY
 2009-03-24 PHE A:58 A:305 117.0 0.557 H -66.8 -40.0 30.0 0.143 0.414 B:O88522:0.414
 HOH
 3.351
 CE1
 O
PHE B:58 B:305 121.0 0.576 H -58.4 -40.3 25.0 0.119 0.457 A:O88522:0.457
 HOH
 3.503
 CZ
 O
2v4h 1 O88522 90.91 1e-44 X-RAY
 2009-11-03 PHE A:78 A:305 111.0 0.529 H -61.9 -52.8 10.0 0.048 0.481 A:O88522:0.257
C:None:0.005
B:O88522:0.305
 HOH
 6.070
 N
 O
PHE B:78 B:305 118.0 0.562 H -42.8 -60.8 27.0 0.129 0.433 A:O88522:0.433
 HOH
 7.109
 O
 O
2zvo 2 O88522 87.78 2e-44 X-RAY
 2009-03-24 PHE C:58 B:305 110.0 0.524 H -68.0 -41.1 10.0 0.048 0.476 D:O88522:0.286
A:Q96C32:0.314
B:Q96C32:0.014
 HOH
 6.470
 CE1
 O
PHE D:58 D:305 118.0 0.562 H -64.0 -40.0 12.0 0.057 0.505 A:Q96C32:0.01
C:O88522:0.324
B:Q96C32:0.324
 HOH
 6.953
 CZ
 O
2zvn 2 O88522 91.76 4e-43 X-RAY
 2009-03-24 PHE C:55 B:305 118.0 0.562 H -50.1 -51.6 12.0 0.057 0.505 D:O88522:0.343
A:Q96C32:0.305
B:Q96C32:0.005
 HOH
 8.316
 O
 O
PHE D:55 D:305 114.0 0.543 H -66.3 -49.4 12.0 0.057 0.486 A:Q96C32:0.005
C:O88522:0.314
B:Q96C32:0.305
 HOH
 8.889
 CE1
 O
PHE G:55 F:305 111.0 0.529 H -47.4 -58.5 NA NA NA
PHE H:55 H:305 107.0 0.51 H -73.7 -53.8 NA NA NA
4bwn 1 Q9Y6K9 94.68 2e-37 X-RAY
 2014-07-23 PHE A:78 A:312 120.0 0.571 H -58.4 -47.6 35.0 0.167 0.404 B:Q9Y6K9:0.405
 HOH
 3.806
 CE1
 O
PHE B:78 B:312 122.0 0.581 H -60.6 -49.6 27.0 0.129 0.452 A:Q9Y6K9:0.452
 HOH
 4.014
 CZ
 O
6xx0 1 D3DWY0 97.7 4e-36 X-RAY
 2021-02-03 PHE A:57 A:312 117.0 0.557 H -50.2 -51.3 3.0 0.014 0.543 D:None:0.305
B:D3DWY0:0.371
 HOH
 3.934
 CZ
 O
PHE B:57 B:312 113.0 0.538 H -56.8 -58.5 0.0 0.0 0.538 A:D3DWY0:0.429
C:None:0.186
 HOH
 3.668
 CD2
 O
6yek 1 D3DWY0 97.7 4e-36 X-RAY
 2021-03-03 PHE A:57 A:312 119.0 0.567 H -67.4 -39.3 32.0 0.152 0.415 B:D3DWY0:0.414
 HOH
 4.001
 CE2
 O
PHE B:57 B:312 121.0 0.576 H -65.9 -38.9 21.0 0.1 0.476 A:D3DWY0:0.476
 HOH
 4.651
 CE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9y6k9-f1 1 Q9Y6K9 100.0 0.0 PHE A:312 A:312 122.0 0.581 H -60.9 -40.3