Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 153791805 | . | A | C | CCDS48196.1:NM_001099856.2:c.1148gAg>gCg_NP_001093326.2:p.383E>A | Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3jsv | 3 | O88522 | 89.36 | 2e-48 |
X-RAY |
2009-10-27 | GLU | C:59 | C:308 | 140.0 | 0.737 | H | -55.5 | -44.6 | 3.0 | 0.016 | 0.721 |
A:P62988:0.179 D:O88522:0.6 |
HOH |
8.157 |
OE2 |
O |
|
GLU | D:59 | D:308 | 145.0 | 0.763 | H | -60.2 | -19.5 | 31.0 | 0.163 | 0.6 |
C:O88522:0.6 |
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3fx0 | 1 | Q9Y6K9 | 97.53 | 3e-46 |
X-RAY |
2009-04-07 | GLU | A:74 | A:315 | 126.0 | 0.663 | H | -62.1 | -42.6 | 30.0 | 0.158 | 0.505 |
B:Q9Y6K9:0.505 |
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GLU | B:74 | B:1315 | 134.0 | 0.705 | H | -90.3 | -26.5 | 13.0 | 0.068 | 0.637 |
A:Q9Y6K9:0.637 |
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4owf | 1 | O88522 | 90.0 | 5e-46 |
X-RAY |
2014-02-12 | GLU | A:59 | A:308 | 134.0 | 0.705 | H | -63.2 | -49.8 | 18.0 | 0.095 | 0.61 |
B:O88522:0.611 |
HOH |
3.336 |
CG |
O |
|
GLU | B:59 | B:308 | 139.0 | 0.732 | H | -68.1 | -43.1 | 17.0 | 0.089 | 0.643 |
A:O88522:0.642 |
HOH |
4.460 |
N |
O |
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3f89 | 1 | O88522 | 88.89 | 1e-45 |
X-RAY |
2009-03-24 | GLU | A:61 | A:308 | 137.0 | 0.721 | H | -72.6 | -38.3 | 24.0 | 0.126 | 0.595 |
B:O88522:0.595 |
HOH |
3.093 |
OE1 |
O |
|
GLU | B:61 | B:308 | 135.0 | 0.711 | H | -54.3 | -60.5 | 19.0 | 0.1 | 0.611 |
A:O88522:0.611 |
HOH |
1.928 |
OE2 |
O |
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2v4h | 1 | O88522 | 90.91 | 1e-44 |
X-RAY |
2009-11-03 | GLU | A:81 | A:308 | 129.0 | 0.679 | H | -54.3 | -57.0 | 1.0 | 0.005 | 0.674 |
D:None:0.168 B:O88522:0.642 |
HOH |
6.656 |
N |
O |
|
GLU | B:81 | B:308 | 135.0 | 0.711 | H | -51.6 | -53.2 | 0.0 | 0.0 | 0.711 |
A:O88522:0.105 A:O88522:0.642 C:None:0.2 |
HOH |
4.355 |
N |
O |
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2zvo | 2 | O88522 | 87.78 | 2e-44 |
X-RAY |
2009-03-24 | GLU | C:61 | B:308 | 139.0 | 0.732 | H | -63.4 | -37.4 | 0.0 | 0.0 | 0.732 |
D:O88522:0.679 B:Q96C32:0.232 |
HOH |
5.761 |
O |
O |
|
GLU | D:61 | D:308 | 140.0 | 0.737 | H | -66.8 | -37.8 | 0.0 | 0.0 | 0.737 |
A:Q96C32:0.253 C:O88522:0.711 |
HOH |
4.465 |
OE2 |
O |
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2zvn | 2 | O88522 | 91.76 | 4e-43 |
X-RAY |
2009-03-24 | GLU | C:58 | B:308 | 140.0 | 0.737 | H | -52.3 | -40.2 | 0.0 | 0.0 | 0.737 |
D:O88522:0.647 B:Q96C32:0.279 |
HOH |
5.341 |
N |
O |
|
GLU | D:58 | D:308 | 135.0 | 0.711 | H | -78.4 | -44.3 | 0.0 | 0.0 | 0.711 |
A:Q96C32:0.253 C:O88522:0.679 |
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GLU | G:58 | F:308 | 142.0 | 0.747 | H | -49.5 | -43.6 | NA | NA | NA | |||||||||||||
GLU | H:58 | H:308 | 133.0 | 0.7 | H | -79.9 | -39.1 | NA | NA | NA | |||||||||||||
4bwn | 1 | Q9Y6K9 | 94.68 | 2e-37 |
X-RAY |
2014-07-23 | GLU | A:81 | A:315 | 133.0 | 0.7 | H | -65.9 | -42.1 | 22.0 | 0.116 | 0.584 |
B:Q9Y6K9:0.584 |
HOH |
5.988 |
OE1 |
O |
|
GLU | B:81 | B:315 | 135.0 | 0.711 | H | -64.2 | -46.2 | 24.0 | 0.126 | 0.585 |
A:Q9Y6K9:0.584 |
HOH |
3.331 |
OE1 |
O |
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6xx0 | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-02-03 | GLU | A:60 | A:315 | 142.0 | 0.747 | H | -65.0 | -40.1 | 14.0 | 0.074 | 0.673 |
C:None:0.079 B:D3DWY0:0.626 |
HOH |
6.544 |
N |
O |
|
GLU | B:60 | B:315 | 137.0 | 0.721 | H | -84.8 | -32.4 | 12.0 | 0.063 | 0.658 |
D:None:0.084 A:D3DWY0:0.611 |
HOH |
2.298 |
OE1 |
O |
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6yek | 1 | D3DWY0 | 97.7 | 4e-36 |
X-RAY |
2021-03-03 | GLU | A:60 | A:315 | 138.0 | 0.726 | H | -70.3 | -37.4 | 14.0 | 0.074 | 0.652 |
B:D3DWY0:0.653 |
HOH |
6.225 |
N |
O |
|
GLU | B:60 | B:315 | 139.0 | 0.732 | H | -70.7 | -38.1 | 24.0 | 0.126 | 0.606 |
A:D3DWY0:0.605 |
HOH |
3.093 |
OE2 |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9y6k9-f1 | 1 | Q9Y6K9 | 100.0 | 0.0 | GLU | A:315 | A:315 | 126.0 | 0.663 | H | -63.3 | -42.5 |