Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133594354 . A C CCDS14641.1:NM_000194.2:c.13Agc>Cgc_NP_000185.1:p.5S>R Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 SER A:4 A:4 117.0 1.0 360.0 138.3 106.0 0.922 0.078 C:P00492:0.096
 HOH
 2.697
 O
 O
SER B:4 B:4 145.0 1.0 360.0 147.7 136.0 1.0 0.0 D:P00492:0.078
 HOH
 2.808
 OG
 O
SER C:4 C:4 144.0 1.0 360.0 142.9 137.0 1.0 0.0 A:P00492:0.061
 HOH
 2.724
 O
 O
SER D:4 D:4 130.0 1.0 360.0 160.0 120.0 1.0 0.0 B:P00492:0.087
 HOH
 2.586
 OG
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 SER A:4 A:4 116.0 1.0 360.0 135.4 103.0 0.896 0.104 B:P00492:0.113
 HOH
 5.966
 N
 O
SER B:4 B:4 146.0 1.0 360.0 125.7 131.0 1.0 0.0 A:P00492:0.13
 HOH
 3.194
 O
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 SER A:4 A:4 130.0 1.0 360.0 116.8 130.0 1.0 0.0 HOH
 2.715
 N
 O
SER B:4 B:4 131.0 1.0 360.0 135.2 118.0 1.0 0.0 A:P00492:0.113
 HOH
 3.050
 O
 O
SER C:4 C:4 118.0 1.0 360.0 137.6 NA NA NA
SER D:4 D:4 132.0 1.0 360.0 157.7 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:4 A:4 102.0 0.887 -69.6 121.9 78.0 0.678 0.209 B:P00492:0.209
 HOH
 2.788
 OG
 O
SER B:4 B:4 52.0 NA -107.4 147.6 44.0 NA NA A:P00492:NA
 HOH
 3.130
 CB
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:4 A:4 143.0 1.0 360.0 131.6 123.0 1.0 0.0 B:P00492:0.174
 HOH
 3.836
 OG
 O
SER B:4 B:4 57.0 NA 123.5 81.5 57.0 NA NA HOH
 2.711
 O
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:4 A:4 140.0 1.0 360.0 130.8 119.0 1.0 0.0 B:P00492:0.183
 HOH
 2.619
 OG
 O
SER B:4 B:4 61.0 NA 95.9 87.5 58.0 NA NA A:P00492:NA
 HOH
 2.740
 CA
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 NA:NA DO NA DO DO DO NA NA NA
SER B:4 B:4 125.0 1.0 360.0 126.9 116.0 1.0 0.0 A:P00492:0.078
 HOH
 7.953
 OG
 O
SER C:4 NA:NA DO NA DO DO DO NA NA NA
SER D:4 D:4 135.0 1.0 360.0 118.6 123.0 1.0 0.0 C:P00492:0.104
 HOH
 3.806
 O
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 A:4 117.0 1.0 360.0 150.3 107.0 0.93 0.07 B:P00492:0.087
 HOH
 3.271
 O
 O
SER B:4 B:4 148.0 1.0 360.0 -51.3 141.0 1.0 0.0 A:P00492:0.061
 HOH
 2.396
 N
 O
SER C:4 NA:NA DO NA DO DO DO NA NA NA
SER D:4 D:4 116.0 1.0 360.0 137.2 104.0 0.904 0.096 C:P00492:0.104
 HOH
 8.043
 OG
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 NA:NA DO NA DO DO DO NA NA NA
SER B:4 B:4 110.0 0.957 360.0 140.8 97.0 0.843 0.114 A:P00492:0.113
 HOH
 2.536
 HB3
 O
SER C:4 C:4 95.0 NA 360.0 78.5 95.0 NA NA HOH
 2.485
 HA
 O
SER D:4 D:4 118.0 1.0 360.0 144.5 103.0 0.896 0.104 C:P00492:0.13
 HOH
 3.125
 O
 O
SER E:4 E:4 58.0 0.504 -87.5 119.5 NA NA NA
SER F:4 F:4 113.0 0.983 360.0 115.1 NA NA NA
SER G:4 NA:NA DO NA DO DO DO NA NA NA
SER H:4 H:4 52.0 0.452 -63.5 156.3 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 A:4 57.0 0.496 -80.2 128.6 48.0 0.417 0.079 B:P00492:0.078
 HOH
 3.789
 O
 O
SER B:4 B:4 70.0 0.609 -75.3 140.5 58.0 0.504 0.105 A:P00492:0.104
 HOH
 3.647
 O
 O
SER C:4 C:4 132.0 1.0 360.0 112.1 122.0 1.0 0.0 D:P00492:0.087
SER D:4 D:4 127.0 1.0 360.0 114.9 116.0 1.0 0.0 C:P00492:0.096
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 A:4 4.0 0.035 B -149.5 75.9 4.0 0.035 0.0 HOH
 3.137
 OG
 O
SER B:4 B:4 125.0 1.0 360.0 131.3 116.0 1.0 0.0 A:P00492:0.078
 HOH
 3.292
 O
 O
SER C:4 C:4 102.0 0.887 360.0 156.1 90.0 0.783 0.104 D:P00492:0.104
 HOH
 3.108
 O
 O
SER D:4 D:4 134.0 1.0 360.0 115.2 124.0 1.0 0.0 C:P00492:0.087
 HOH
 3.757
 O
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:4 A:4 131.0 1.0 360.0 136.2 122.0 1.0 0.0 B:P00492:0.078
 HOH
 2.330
 N
 O
SER B:4 B:4 118.0 1.0 360.0 142.4 105.0 0.913 0.087 A:P00492:0.113
 HOH
 3.716
 OG
 O
SER C:4 NA:NA DO NA DO DO DO NA NA NA
SER D:4 D:4 53.0 0.461 -48.0 139.3 41.0 0.357 0.104 C:P00492:0.104
 HOH
 7.771
 OG
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 SER A:10 A:4 121.0 1.0 360.0 158.5 110.0 0.957 0.043 B:P00492:0.096
 HOH
 2.639
 O
 O
SER B:10 B:4 119.0 1.0 360.0 159.5 110.0 0.957 0.043 A:P00492:0.078
 HOH
 3.131
 OG
 O
SER C:10 NA:NA DO NA DO DO DO NA NA NA
SER D:10 D:4 115.0 1.0 360.0 134.6 106.0 0.922 0.078 C:P00492:0.078
 HOH
 3.202
 O
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 SER A:3 A:4 151.0 1.0 360.0 -51.6 151.0 1.0 0.0 HOH
 6.947
 HG
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 SER A:5 A:4 63.0 0.548 -66.9 128.9 50.0 0.435 0.113 B:P00492:0.113
 HOH
 2.315
 O
 O
SER B:5 B:4 63.0 0.548 -74.6 127.3 50.0 0.435 0.113 A:P00492:0.113
 HOH
 2.261
 O
 O
SER C:5 C:4 90.0 NA 360.0 -43.7 90.0 NA NA HOH
 3.101
 O
 O
SER D:5 D:4 36.0 0.313 -161.3 144.4 25.0 0.217 0.096 C:P00492:0.096
 HOH
 2.956
 O
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 SER A:11 A:4 66.0 0.574 -64.2 128.1 52.0 0.452 0.122 B:P00492:0.122
 HOH
 2.844
 O
 O
SER B:11 B:4 56.0 0.487 -102.3 175.7 43.0 0.374 0.113 A:P00492:0.113
 HOH
 3.125
 O
 O
SER C:11 C:4 137.0 1.0 360.0 114.2 129.0 1.0 0.0 D:P00492:0.07
 HOH
 2.719
 O
 O
SER D:11 D:4 125.0 1.0 360.0 158.7 107.0 0.93 0.07 C:P00492:0.157
 HOH
 3.839
 OG
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 SER A:5 A:4 114.0 0.991 360.0 114.8 107.0 0.93 0.061 C:P00492:0.061
 HOH
 3.171
 O
 O
SER B:5 B:4 113.0 0.983 360.0 129.3 103.0 0.896 0.087 D:P00492:0.087
 HOH
 3.400
 CB
 O
SER C:5 NA:NA DO NA DO DO DO NA NA NA
SER D:5 D:4 150.0 1.0 360.0 143.3 135.0 1.0 0.0 B:P00492:0.13
 HOH
 3.433
 CB
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 SER A:5 A:4 144.0 1.0 360.0 136.8 132.0 1.0 0.0 D:P00492:0.104
 HOH
 3.826
 O
 O
SER B:5 NA:NA DO NA DO DO DO NA NA NA
SER C:5 C:4 140.0 1.0 360.0 138.3 127.0 1.0 0.0 B:P00492:0.113
 HOH
 4.992
 O
 O
SER D:5 NA:NA DO NA DO DO DO NA NA NA
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 SER A:2 A:4 67.0 0.583 -81.9 151.2 51.0 0.443 0.14 B:P00492:0.139
 HOH
 3.697
 O
 O
SER B:2 B:4 138.0 1.0 360.0 132.3 125.0 1.0 0.0 A:P00492:0.113
 HOH
 2.434
 O
 O
SER C:2 NA:NA DO NA DO DO DO NA NA NA
SER D:2 D:4 136.0 1.0 360.0 143.8 107.0 0.93 0.07 C:P00492:0.252
 HOH
 2.378
 O
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 SER A:1 A:4 120.0 1.0 360.0 153.2 120.0 1.0 0.0 HOH
 2.487
 OG
 O
SER B:1 B:4 164.0 1.0 360.0 73.5 164.0 1.0 0.0 HOH
 5.527
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 SER A:5 A:5 68.0 0.591 -64.8 133.8