Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chrX | 133607408 | . | G | A | CCDS14641.1:NM_000194.2:c.47gGt>gAt_NP_000185.1:p.16G>D | Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1bzy | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
1999-06-22 | GLY | A:15 | A:15 | 6.0 | 0.08 | 73.3 | -163.2 | 6.0 | 0.08 | 0.0 |
HOH |
4.203 |
O |
O |
|||
GLY | B:15 | B:15 | 9.0 | 0.12 | 75.5 | -164.6 | 9.0 | 0.12 | 0.0 |
HOH |
3.074 |
O |
O |
||||||||||
GLY | C:15 | C:15 | 19.0 | 0.253 | 97.8 | -166.5 | 19.0 | 0.253 | 0.0 |
HOH |
3.009 |
CA |
O |
||||||||||
GLY | D:15 | D:15 | 7.0 | 0.093 | 74.0 | -141.9 | 7.0 | 0.093 | 0.0 |
HOH |
6.199 |
O |
O |
||||||||||
1hmp | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
1995-06-03 | GLY | A:15 | A:15 | 9.0 | 0.12 | 79.0 | -136.7 | 9.0 | 0.12 | 0.0 |
HOH |
4.561 |
O |
O |
|||
GLY | B:15 | B:15 | 18.0 | 0.24 | 71.3 | -155.2 | 18.0 | 0.24 | 0.0 |
HOH |
7.184 |
CA |
O |
||||||||||
1z7g | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2005-08-02 | GLY | A:15 | A:15 | 10.0 | 0.133 | 109.5 | -178.5 | 10.0 | 0.133 | 0.0 |
HOH |
5.129 |
N |
O |
|||
GLY | B:15 | B:15 | 6.0 | 0.08 | 110.8 | 170.2 | 6.0 | 0.08 | 0.0 |
HOH |
3.883 |
O |
O |
||||||||||
GLY | C:15 | C:15 | 7.0 | 0.093 | 77.8 | -167.8 | NA | NA | NA | ||||||||||||||
GLY | D:15 | D:15 | 8.0 | 0.107 | 66.0 | -176.3 | NA | NA | NA | ||||||||||||||
3gep | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:15 | A:15 | 11.0 | 0.147 | -73.5 | 175.0 | 11.0 | 0.147 | 0.0 |
HOH |
3.958 |
O |
O |
|||
GLY | B:15 | B:15 | 22.0 | 0.293 | S | 71.1 | -147.4 | 22.0 | 0.293 | 0.0 |
HOH |
3.225 |
N |
O |
|||||||||
3ggc | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:15 | A:15 | 18.0 | 0.24 | S | -131.7 | -106.5 | 18.0 | 0.24 | 0.0 |
HOH |
4.213 |
O |
O |
||
GLY | B:15 | B:15 | 24.0 | 0.32 | S | 78.0 | -150.6 | 24.0 | 0.32 | 0.0 |
HOH |
2.944 |
O |
O |
|||||||||
3ggj | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2009-08-18 | GLY | A:15 | A:15 | 20.0 | 0.267 | S | -133.1 | -111.7 | 20.0 | 0.267 | 0.0 |
HOH |
3.957 |
O |
O |
||
GLY | B:15 | B:15 | 22.0 | 0.293 | S | 77.5 | -149.6 | 22.0 | 0.293 | 0.0 |
HOH |
3.187 |
O |
O |
|||||||||
4rab | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 6.0 | 0.08 | 73.0 | -162.5 | 6.0 | 0.08 | 0.0 |
HOH |
5.723 |
CA |
O |
|||
GLY | B:15 | B:15 | 5.0 | 0.067 | 70.7 | -169.6 | 5.0 | 0.067 | 0.0 |
HOH |
4.180 |
O |
O |
||||||||||
GLY | C:15 | C:15 | 5.0 | 0.067 | 83.9 | -165.0 | 5.0 | 0.067 | 0.0 |
HOH |
5.785 |
O |
O |
||||||||||
GLY | D:15 | D:15 | 6.0 | 0.08 | 75.2 | -159.9 | 6.0 | 0.08 | 0.0 |
HOH |
6.329 |
O |
O |
||||||||||
4rac | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 5.0 | 0.067 | 67.3 | -166.2 | 5.0 | 0.067 | 0.0 |
HOH |
2.658 |
O |
O |
|||
GLY | B:15 | B:15 | 6.0 | 0.08 | 70.8 | -165.5 | 6.0 | 0.08 | 0.0 |
HOH |
5.981 |
CA |
O |
||||||||||
GLY | C:15 | C:15 | 6.0 | 0.08 | 64.5 | -168.2 | 6.0 | 0.08 | 0.0 |
HOH |
6.122 |
O |
O |
||||||||||
GLY | D:15 | D:15 | 6.0 | 0.08 | 73.6 | -165.2 | 6.0 | 0.08 | 0.0 |
HOH |
6.386 |
O |
O |
||||||||||
4rad | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 6.0 | 0.08 | 73.6 | -158.8 | 6.0 | 0.08 | 0.0 |
HOH |
2.524 |
O |
O |
|||
GLY | B:15 | B:15 | 4.0 | 0.053 | 72.1 | -164.3 | 4.0 | 0.053 | 0.0 |
HOH |
4.280 |
H |
O |
||||||||||
GLY | C:15 | C:15 | 8.0 | 0.107 | 71.6 | -152.4 | 8.0 | 0.107 | 0.0 |
HOH |
2.766 |
O |
O |
||||||||||
GLY | D:15 | D:15 | 6.0 | 0.08 | 72.0 | -154.9 | 6.0 | 0.08 | 0.0 |
HOH |
3.783 |
O |
O |
||||||||||
GLY | E:15 | E:15 | 6.0 | 0.08 | 75.4 | -160.4 | NA | NA | NA | ||||||||||||||
GLY | F:15 | F:15 | 5.0 | 0.067 | 73.4 | -159.7 | NA | NA | NA | ||||||||||||||
GLY | G:15 | G:15 | 7.0 | 0.093 | 70.2 | -147.3 | NA | NA | NA | ||||||||||||||
GLY | H:15 | H:15 | 6.0 | 0.08 | 79.5 | -157.0 | NA | NA | NA | ||||||||||||||
4ran | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 5.0 | 0.067 | 74.6 | -167.7 | 5.0 | 0.067 | 0.0 |
HOH |
6.705 |
N |
O |
|||
GLY | B:15 | B:15 | 7.0 | 0.093 | 72.0 | -164.3 | 7.0 | 0.093 | 0.0 |
HOH |
6.773 |
N |
O |
||||||||||
GLY | C:15 | C:15 | 7.0 | 0.093 | 75.5 | -165.5 | 7.0 | 0.093 | 0.0 | ||||||||||||||
GLY | D:15 | D:15 | 6.0 | 0.08 | 69.7 | -157.7 | 6.0 | 0.08 | 0.0 | ||||||||||||||
4rao | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 6.0 | 0.08 | 67.6 | -165.3 | 6.0 | 0.08 | 0.0 |
HOH |
5.946 |
N |
O |
|||
GLY | B:15 | B:15 | 5.0 | 0.067 | 68.9 | -166.7 | 5.0 | 0.067 | 0.0 |
HOH |
4.315 |
O |
O |
||||||||||
GLY | C:15 | C:15 | 7.0 | 0.093 | 58.9 | -151.0 | 7.0 | 0.093 | 0.0 |
HOH |
6.476 |
O |
O |
||||||||||
GLY | D:15 | D:15 | 5.0 | 0.067 | 69.2 | -159.9 | 5.0 | 0.067 | 0.0 |
HOH |
5.735 |
O |
O |
||||||||||
4raq | 1 | P00492 | 100.0 | 3e-161 |
X-RAY |
2015-01-07 | GLY | A:15 | A:15 | 6.0 | 0.08 | 58.0 | -145.8 | 6.0 | 0.08 | 0.0 |
HOH |
7.165 |
N |
O |
|||
GLY | B:15 | B:15 | 9.0 | 0.12 | 62.8 | -157.8 | 9.0 | 0.12 | 0.0 |
HOH |
6.160 |
N |
O |
||||||||||
GLY | C:15 | C:15 | 6.0 | 0.08 | 91.7 | -159.1 | 6.0 | 0.08 | 0.0 |
HOH |
5.278 |
O |
O |
||||||||||
GLY | D:15 | D:15 | 8.0 | 0.107 | 78.2 | -164.7 | 8.0 | 0.107 | 0.0 |
HOH |
6.699 |
O |
O |
||||||||||
4ijq | 1 | P00492 | 100.0 | 4e-161 |
X-RAY |
2013-03-27 | GLY | A:21 | A:15 | 6.0 | 0.08 | 72.7 | -167.4 | 6.0 | 0.08 | 0.0 |
HOH |
4.069 |
O |
O |
|||
GLY | B:21 | B:15 | 13.0 | 0.173 | 60.7 | -167.0 | 13.0 | 0.173 | 0.0 |
HOH |
4.059 |
O |
O |
||||||||||
GLY | C:21 | C:15 | 6.0 | 0.08 | 64.4 | -165.2 | 6.0 | 0.08 | 0.0 |
HOH |
3.993 |
O |
O |
||||||||||
GLY | D:21 | D:15 | 6.0 | 0.08 | 58.1 | -158.5 | 6.0 | 0.08 | 0.0 |
HOH |
4.143 |
O |
O |
||||||||||
4kn6 | 1 | P00492 | 100.0 | 1e-160 |
X-RAY |
2013-08-14 | GLY | A:14 | A:15 | 12.0 | 0.16 | S | 72.9 | 108.6 | 12.0 | 0.16 | 0.0 |
HOH |
4.291 |
H |
O |
||
6bnj | 1 | P00492 | 99.08 | 6e-160 |
X-RAY |
2017-12-06 | GLY | A:16 | A:15 | 6.0 | 0.08 | 69.4 | -165.1 | 6.0 | 0.08 | 0.0 |
HOH |
4.300 |
O |
O |
|||
GLY | B:16 | B:15 | 14.0 | 0.187 | 72.6 | -164.2 | 14.0 | 0.187 | 0.0 |
HOH |
2.630 |
O |
O |
||||||||||
GLY | C:16 | C:15 | 6.0 | 0.08 | 71.9 | -167.7 | 6.0 | 0.08 | 0.0 |
HOH |
4.131 |
O |
O |
||||||||||
GLY | D:16 | D:15 | 5.0 | 0.067 | 65.7 | -160.4 | 5.0 | 0.067 | 0.0 |
HOH |
2.908 |
O |
O |
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5hia | 1 | P00492 | 99.08 | 8e-160 |
X-RAY |
2017-01-18 | GLY | A:22 | A:15 | 7.0 | 0.093 | 71.9 | -160.6 | 7.0 | 0.093 | 0.0 |
HOH |
4.350 |
O |
O |
|||
GLY | B:22 | B:15 | 7.0 | 0.093 | 70.2 | -169.2 | 7.0 | 0.093 | 0.0 |
HOH |
3.083 |
O |
O |
||||||||||
GLY | C:22 | C:15 | 15.0 | 0.2 | 70.1 | -166.5 | 15.0 | 0.2 | 0.0 |
HOH |
2.662 |
O |
O |
||||||||||
GLY | D:22 | D:15 | 7.0 | 0.093 | 66.2 | -164.6 | 7.0 | 0.093 | 0.0 |
HOH |
3.985 |
O |
O |
||||||||||
5brn | 1 | P00492 | 98.62 | 3e-159 |
X-RAY |
2015-10-14 | GLY | A:16 | A:15 | 5.0 | 0.067 | 83.1 | -162.7 | 5.0 | 0.067 | 0.0 |
HOH |
6.051 |
O |
O |
|||
GLY | B:16 | B:15 | 18.0 | 0.24 | 80.7 | -145.5 | 18.0 | 0.24 | 0.0 |
HOH |
4.547 |
O |
O |
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GLY | C:16 | C:15 | 8.0 | 0.107 | 82.1 | -159.8 | 8.0 | 0.107 | 0.0 |
HOH |
3.516 |
O |
O |
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GLY | D:16 | D:15 | 7.0 | 0.093 | 78.6 | -160.1 | 7.0 | 0.093 | 0.0 |
HOH |
5.670 |
N |
O |
||||||||||
5bsk | 1 | P00492 | 98.62 | 3e-159 |
X-RAY |
2015-09-23 | GLY | A:16 | A:15 | 45.0 | 0.6 | 360.0 | -147.7 | 45.0 | 0.6 | 0.0 |
HOH |
6.647 |
O |
O |
|||
GLY | B:16 | B:15 | 41.0 | 0.547 | 360.0 | -159.4 | 41.0 | 0.547 | 0.0 |
HOH |
6.064 |
O |
O |
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GLY | C:16 | C:15 | 54.0 | 0.72 | 360.0 | -156.7 | 54.0 | 0.72 | 0.0 | ||||||||||||||
GLY | D:16 | D:15 | 25.0 | 0.333 | 100.9 | -134.5 | 25.0 | 0.333 | 0.0 |
HOH |
2.433 |
O |
O |
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5w8v | 1 | P00492 | 100.0 | 7e-159 |
X-RAY |
2017-08-30 | GLY | A:13 | A:15 | 8.0 | 0.107 | 91.4 | -163.1 | 8.0 | 0.107 | 0.0 |
HOH |
4.750 |
O |
O |
|||
GLY | B:13 | B:15 | 7.0 | 0.093 | 76.2 | -155.9 | 7.0 | 0.093 | 0.0 |
HOH |
3.773 |
O |
O |
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GLY | C:13 | C:15 | 6.0 | 0.08 | 82.9 | -145.0 | 6.0 | 0.08 | 0.0 |
HOH |
6.149 |
O |
O |
||||||||||
GLY | D:13 | D:15 | 7.0 | 0.093 | 79.4 | -149.2 | 7.0 | 0.093 | 0.0 |
HOH |
4.176 |
O |
O |
||||||||||
1d6n | 1 | P00492 | 99.07 | 6e-157 |
X-RAY |
1999-12-30 | GLY | A:12 | A:15 | 4.0 | 0.053 | 56.1 | -154.8 | 4.0 | 0.053 | 0.0 | |||||||
GLY | B:12 | B:15 | 9.0 | 0.12 | 91.4 | -147.6 | 9.0 | 0.12 | 0.0 |
HOH |
8.752 |
N |
O |
||||||||||
2vfa | 1 | P20035,P00492 | 80.48 | 3e-122 |
X-RAY |
2008-06-17 | GLY | A:24 | A:24 | 33.0 | 0.44 | 155.5 | -173.5 | 33.0 | 0.44 | 0.0 |
HOH |
2.989 |
O |
O |
|||
GLY | B:24 | B:24 | 27.0 | 0.36 | 144.3 | -179.7 | 27.0 | 0.36 | 0.0 |
HOH |
2.653 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00492-f1 | 1 | P00492 | 100.0 | 2e-162 | GLY | A:16 | A:16 | 12.0 | 0.16 | 67.6 | -159.7 |