Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133607483 . T A CCDS14641.1:NM_000194.2:c.122cTa>cAa_NP_000185.1:p.41L>Q Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 LEU A:40 A:40 68.0 0.4 H -69.5 -37.0 8.0 0.047 0.353 C:P00492:0.353
 HOH
 3.727
 CD1
 O
LEU B:40 B:40 64.0 0.376 H -68.0 -42.0 2.0 0.012 0.364 D:P00492:0.365
 HOH
 5.629
 CD1
 O
LEU C:40 C:40 66.0 0.388 H -67.8 -37.7 6.0 0.035 0.353 A:P00492:0.353
 HOH
 3.353
 CD1
 O
LEU D:40 D:40 62.0 0.365 H -65.9 -37.1 5.0 0.029 0.336 B:P00492:0.335
 HOH
 5.275
 CD1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 LEU A:40 A:40 79.0 0.465 H -57.4 -49.1 9.0 0.053 0.412 B:P00492:0.412
 HOH
 5.077
 CD2
 O
LEU B:40 B:40 74.0 0.435 H -62.7 -36.3 6.0 0.035 0.4 A:P00492:0.4
 HOH
 3.107
 CD1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 LEU A:40 A:40 70.0 0.412 H -68.0 -38.2 3.0 0.018 0.394 B:P00492:0.394
 HOH
 3.551
 CD2
 O
LEU B:40 B:40 74.0 0.435 H -70.7 -36.1 5.0 0.029 0.406 A:P00492:0.406
 HOH
 3.561
 CD2
 O
LEU C:40 C:40 74.0 0.435 H -70.2 -36.9 NA NA NA
LEU D:40 D:40 73.0 0.429 H -71.2 -38.3 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:40 A:40 60.0 0.353 H -58.4 -45.8 2.0 0.012 0.341 B:P00492:0.341
 HOH
 3.680
 CD1
 O
LEU B:40 B:40 59.0 0.347 H -71.8 -39.2 3.0 0.018 0.329 A:P00492:0.329
 HOH
 6.791
 CD1
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:40 A:40 59.0 0.347 H -70.4 -36.7 4.0 0.024 0.323 B:P00492:0.324
 HOH
 6.020
 N
 O
LEU B:40 B:40 54.0 0.318 H -77.1 -38.2 1.0 0.006 0.312 A:P00492:0.312
 HOH
 5.455
 N
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:40 A:40 57.0 0.335 H -67.8 -39.1 4.0 0.024 0.311 B:P00492:0.312
 HOH
 6.484
 N
 O
LEU B:40 B:40 57.0 0.335 H -69.7 -38.0 2.0 0.012 0.323 A:P00492:0.324
 HOH
 5.890
 N
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 69.0 0.406 H -65.9 -37.9 4.0 0.024 0.382 B:P00492:0.382
 HOH
 4.039
 CD2
 O
LEU B:40 B:40 67.0 0.394 H -65.8 -36.8 4.0 0.024 0.37 A:P00492:0.371
 HOH
 6.807
 O
 O
LEU C:40 C:40 71.0 0.418 H -66.8 -36.4 6.0 0.035 0.383 D:P00492:0.382
 HOH
 6.336
 N
 O
LEU D:40 D:40 71.0 0.418 H -64.9 -38.5 5.0 0.029 0.389 C:P00492:0.388
 HOH
 5.872
 N
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 64.0 0.376 H -65.8 -41.6 5.0 0.029 0.347 B:P00492:0.347
 HOH
 6.301
 N
 O
LEU B:40 B:40 64.0 0.376 H -66.9 -38.8 4.0 0.024 0.352 A:P00492:0.353
 HOH
 3.476
 CD1
 O
LEU C:40 C:40 66.0 0.388 H -63.3 -49.1 5.0 0.029 0.359 D:P00492:0.359
 HOH
 6.537
 N
 O
LEU D:40 D:40 65.0 0.382 H -61.6 -48.7 7.0 0.041 0.341 C:P00492:0.341
 HOH
 6.115
 N
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 65.0 0.382 H -64.6 -42.7 6.0 0.035 0.347 B:P00492:0.347
 HOH
 3.448
 HD12
 O
LEU B:40 B:40 63.0 0.371 H -64.4 -36.5 5.0 0.029 0.342 A:P00492:0.341
 HOH
 3.533
 HD12
 O
LEU C:40 C:40 67.0 0.394 H -62.8 -39.4 7.0 0.041 0.353 D:P00492:0.353
 HOH
 5.757
 H
 O
LEU D:40 D:40 67.0 0.394 H -61.6 -40.3 6.0 0.035 0.359 C:P00492:0.359
 HOH
 5.585
 HD11
 O
LEU E:40 E:40 62.0 0.365 H -61.6 -43.5 NA NA NA
LEU F:40 F:40 61.0 0.359 H -65.8 -40.1 NA NA NA
LEU G:40 G:40 62.0 0.365 H -64.2 -42.4 NA NA NA
LEU H:40 H:40 64.0 0.376 H -64.2 -38.2 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 69.0 0.406 H -63.0 -41.5 6.0 0.035 0.371 B:P00492:0.371
 HOH
 6.180
 N
 O
LEU B:40 B:40 69.0 0.406 H -64.3 -39.9 4.0 0.024 0.382 A:P00492:0.382
 HOH
 6.486
 N
 O
LEU C:40 C:40 69.0 0.406 H -63.6 -40.0 8.0 0.047 0.359 D:P00492:0.359
 HOH
 6.293
 N
 O
LEU D:40 D:40 74.0 0.435 H -61.9 -40.0 9.0 0.053 0.382 C:P00492:0.382
 HOH
 6.517
 N
 O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 64.0 0.376 H -65.9 -37.0 3.0 0.018 0.358 B:P00492:0.359
 HOH
 5.995
 N
 O
LEU B:40 B:40 67.0 0.394 H -69.9 -36.5 5.0 0.029 0.365 A:P00492:0.365
 HOH
 4.089
 CD2
 O
LEU C:40 C:40 69.0 0.406 H -65.6 -39.3 5.0 0.029 0.377 D:P00492:0.376
 HOH
 5.769
 N
 O
LEU D:40 D:40 68.0 0.4 H -66.5 -39.8 5.0 0.029 0.371 C:P00492:0.371
 HOH
 6.090
 N
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:40 A:40 67.0 0.394 H -72.4 -39.5 5.0 0.029 0.365 B:P00492:0.365
 HOH
 7.151
 O
 O
LEU B:40 B:40 61.0 0.359 H -62.7 -36.6 2.0 0.012 0.347 A:P00492:0.347
 HOH
 6.858
 O
 O
LEU C:40 C:40 67.0 0.394 H -58.7 -38.0 3.0 0.018 0.376 D:P00492:0.376
 HOH
 6.119
 N
 O
LEU D:40 D:40 63.0 0.371 H -63.0 -39.9 3.0 0.018 0.353 C:P00492:0.353
 HOH
 6.627
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 LEU A:46 A:40 62.0 0.365 H -67.4 -39.5 5.0 0.029 0.336 B:P00492:0.335
 HOH
 4.015
 CD1
 O
LEU B:46 B:40 68.0 0.4 H -67.9 -39.5 6.0 0.035 0.365 A:P00492:0.365
 HOH
 3.664
 CD1
 O
LEU C:46 C:40 69.0 0.406 H -63.1 -45.1 7.0 0.041 0.365 D:P00492:0.365
 HOH
 3.952
 CD1
 O
LEU D:46 D:40 68.0 0.4 H -61.0 -44.1 8.0 0.047 0.353 C:P00492:0.353
 HOH
 5.900
 N
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 LEU A:39 A:40 63.0 0.371 H -73.3 -41.0 63.0 0.371 0.0 HOH
 6.598
 O
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 LEU A:41 A:40 67.0 0.394 H -67.8 -39.9 5.0 0.029 0.365 B:P00492:0.365
 HOH
 3.468
 CD2
 O
LEU B:41 B:40 66.0 0.388 H -67.4 -38.6 4.0 0.024 0.364 A:P00492:0.365
 HOH
 3.640
 CD2
 O
LEU C:41 C:40 71.0 0.418 H -68.5 -41.5 8.0 0.047 0.371 D:P00492:0.371
 HOH
 3.512
 CD2
 O
LEU D:41 D:40 66.0 0.388 H -65.7 -42.0 3.0 0.018 0.37 C:P00492:0.371
 HOH
 3.560
 CD2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 LEU A:47 A:40 66.0 0.388 H -67.0 -38.8 4.0 0.024 0.364 B:P00492:0.365
 HOH
 3.673
 CD2
 O
LEU B:47 B:40 70.0 0.412 H -68.3 -38.8 4.0 0.024 0.388 A:P00492:0.388
 HOH
 3.929
 CD2
 O
LEU C:47 C:40 70.0 0.412 H -69.0 -39.1 5.0 0.029 0.383 D:P00492:0.382
 HOH
 3.867
 CD2
 O
LEU D:47 D:40 71.0 0.418 H -67.9 -39.1 5.0 0.029 0.389 C:P00492:0.388
 HOH
 3.618
 CD2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 LEU A:41 A:40 66.0 0.388 H -66.5 -35.7 3.0 0.018 0.37 C:P00492:0.371
 HOH
 4.664
 CD2
 O
LEU B:41 B:40 65.0 0.382 H -66.7 -36.0 6.0 0.035 0.347 D:P00492:0.347
 HOH
 6.211
 CD2
 O
LEU C:41 C:40 64.0 0.376 H -67.9 -34.1 4.0 0.024 0.352 A:P00492:0.353
 HOH
 6.471
 CD2
 O
LEU D:41 D:40 68.0 0.4 H -71.2 -35.2 6.0 0.035 0.365 B:P00492:0.365
 HOH
 5.826
 N
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 LEU A:41 A:40 64.0 0.376 H -67.3 -33.6 3.0 0.018 0.358 D:P00492:0.359
 HOH
 6.331
 N
 O
LEU B:41 B:40 63.0 0.371 H -66.6 -32.6 2.0 0.012 0.359 C:P00492:0.359
 HOH
 6.422
 N
 O
LEU C:41 C:40 64.0 0.376 H -65.4 -36.4 4.0 0.024 0.352 B:P00492:0.353
 HOH
 5.958
 N
 O
LEU D:41 D:40 65.0 0.382 H -61.8 -39.7 4.0 0.024 0.358 A:P00492:0.359
 HOH
 6.731
 N
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 LEU A:38 A:40 63.0 0.371 H -66.8 -36.9 5.0 0.029 0.342 B:P00492:0.341
 HOH
 6.030
 N
 O
LEU B:38 B:40 65.0 0.382 H -68.1 -36.2 5.0 0.029 0.353 A:P00492:0.353
 HOH
 5.865
 N
 O
LEU C:38 C:40 61.0 0.359 H -65.1 -41.2 3.0 0.018 0.341 D:P00492:0.341
 HOH
 3.237
 CD1
 O
LEU D:38 D:40 65.0 0.382 H -64.8 -39.9 4.0 0.024 0.358 C:P00492:0.359
 HOH
 4.668
 CD2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 LEU A:37 A:40 86.0 0.506 H -36.0 -19.8 86.0 0.506 0.0 HOH
 8.144
 O
 O
LEU B:37 B:40 65.0 0.382 H -72.9 -52.4 65.0 0.382 0.0 HOH
 9.721
 N
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 VAL A:49 A:49 53.0 0.342 H -66.4 -47.9 1.0 0.006 0.336 B:P20035+P00492:0.335
 HOH
 6.109
 N
 O
VAL B:49 B:49 54.0 0.348 H -74.5 -40.3 1.0 0.006 0.342 A:P20035+P00492:0.342
 HOH
 6.262
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 LEU A:41 A:41 69.0 0.406 H -65.8 -34.3