Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133607495 . G A CCDS14641.1:NM_000194.2:c.134aGg>aAg_NP_000185.1:p.45R>K Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ARG A:44 A:44 34.0 0.151 H -68.5 -41.0 2.0 0.009 0.142 C:P00492:0.142
 HOH
 2.927
 NH1
 O
ARG B:44 B:44 41.0 0.182 H -67.8 -39.1 7.0 0.031 0.151 D:P00492:0.151
 HOH
 2.841
 NH2
 O
ARG C:44 C:44 35.0 0.156 H -67.2 -42.3 5.0 0.022 0.134 A:P00492:0.133
 HOH
 2.808
 NH1
 O
ARG D:44 D:44 38.0 0.169 H -72.7 -34.6 7.0 0.031 0.138 B:P00492:0.138
 HOH
 2.852
 NH1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ARG A:44 A:44 32.0 0.142 H -66.9 -47.1 1.0 0.004 0.138 B:P00492:0.138
 HOH
 4.553
 N
 O
ARG B:44 B:44 41.0 0.182 H -58.1 -33.4 5.0 0.022 0.16 A:P00492:0.16
 HOH
 2.735
 NH1
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ARG A:44 A:44 43.0 0.191 H -65.5 -42.3 7.0 0.031 0.16 B:P00492:0.16
 HOH
 2.536
 NH2
 O
ARG B:44 B:44 39.0 0.173 H -65.3 -44.2 4.0 0.018 0.155 A:P00492:0.156
 HOH
 3.003
 NH1
 O
ARG C:44 C:44 39.0 0.173 H -67.2 -40.6 NA NA NA
ARG D:44 D:44 46.0 0.204 H -66.6 -41.4 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:44 A:44 42.0 0.187 H -66.4 -41.5 9.0 0.04 0.147 B:P00492:0.147
 HOH
 2.713
 NH2
 O
ARG B:44 B:44 34.0 0.151 H -69.3 -39.0 3.0 0.013 0.138 A:P00492:0.138
 HOH
 2.810
 NH1
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:44 A:44 40.0 0.178 H -63.2 -48.8 8.0 0.036 0.142 B:P00492:0.142
 HOH
 4.441
 NH2
 O
ARG B:44 B:44 42.0 0.187 H -61.8 -48.8 8.0 0.036 0.151 A:P00492:0.151
 HOH
 3.989
 NH2
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:44 A:44 44.0 0.196 H -60.8 -41.7 9.0 0.04 0.156 B:P00492:0.156
 HOH
 2.736
 NH2
 O
ARG B:44 B:44 39.0 0.173 H -58.8 -44.0 5.0 0.022 0.151 A:P00492:0.151
 HOH
 3.776
 NH2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 43.0 0.191 H -66.0 -41.8 8.0 0.036 0.155 B:P00492:0.156
 HOH
 3.062
 NH2
 O
ARG B:44 B:44 33.0 0.147 H -71.6 -40.6 3.0 0.013 0.134 A:P00492:0.133
 HOH
 4.688
 N
 O
ARG C:44 C:44 48.0 0.213 H -65.0 -40.1 13.0 0.058 0.155 D:P00492:0.156
 HOH
 2.833
 NH1
 O
ARG D:44 D:44 36.0 0.16 H -66.4 -42.0 6.0 0.027 0.133 C:P00492:0.133
 HOH
 2.767
 NH1
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 29.0 0.129 H -65.9 -41.1 1.0 0.004 0.125 B:P00492:0.124
 HOH
 2.770
 NH1
 O
ARG B:44 B:44 41.0 0.182 H -63.1 -40.6 8.0 0.036 0.146 A:P00492:0.147
 HOH
 2.550
 NH2
 O
ARG C:44 C:44 46.0 0.204 H -67.6 -40.0 13.0 0.058 0.146 D:P00492:0.147
 HOH
 2.631
 NH1
 O
ARG D:44 D:44 31.0 0.138 H -61.3 -43.5 3.0 0.013 0.125 C:P00492:0.124
 HOH
 4.611
 N
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 45.0 0.2 H -65.6 -37.3 11.0 0.049 0.151 B:P00492:0.151
 HOH
 1.824
 HH12
 O
ARG B:44 B:44 32.0 0.142 H -70.2 -39.3 3.0 0.013 0.129 A:P00492:0.129
 HOH
 1.932
 HH12
 O
ARG C:44 C:44 39.0 0.173 H -69.0 -41.3 3.0 0.013 0.16 D:P00492:0.16
 HOH
 1.852
 HH12
 O
ARG D:44 D:44 33.0 0.147 H -65.2 -43.2 3.0 0.013 0.134 C:P00492:0.133
 HOH
 2.128
 HH12
 O
ARG E:44 E:44 31.0 0.138 H -64.1 -45.4 NA NA NA
ARG F:44 F:44 29.0 0.129 H -67.7 -45.3 NA NA NA
ARG G:44 G:44 49.0 0.218 H -69.3 -38.1 NA NA NA
ARG H:44 H:44 30.0 0.133 H -67.7 -40.0 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 34.0 0.151 H -62.1 -42.1 3.0 0.013 0.138 B:P00492:0.138
 HOH
 3.854
 NH2
 O
ARG B:44 B:44 35.0 0.156 H -70.0 -39.4 5.0 0.022 0.134 A:P00492:0.133
 HOH
 3.638
 NH2
 O
ARG C:44 C:44 32.0 0.142 H -59.6 -40.2 2.0 0.009 0.133 D:P00492:0.133
ARG D:44 D:44 33.0 0.147 H -67.8 -38.8 2.0 0.009 0.138 C:P00492:0.138
 HOH
 7.614
 N
 O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 30.0 0.133 H -67.8 -42.0 1.0 0.004 0.129 B:P00492:0.129
 HOH
 2.737
 NH1
 O
ARG B:44 B:44 36.0 0.16 H -69.8 -40.8 4.0 0.018 0.142 A:P00492:0.142
 HOH
 2.769
 NH1
 O
ARG C:44 C:44 28.0 0.124 H -67.3 -39.8 0.0 0.0 0.124 D:P00492:0.124
 HOH
 2.721
 NH1
 O
ARG D:44 D:44 33.0 0.147 H -65.5 -39.9 4.0 0.018 0.129 C:P00492:0.129
 HOH
 2.567
 NH1
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:44 A:44 32.0 0.142 H -69.0 -37.3 3.0 0.013 0.129 B:P00492:0.129
 HOH
 3.759
 NH2
 O
ARG B:44 B:44 30.0 0.133 H -66.5 -41.4 2.0 0.009 0.124 A:P00492:0.124
 HOH
 2.829
 NH1
 O
ARG C:44 C:44 49.0 0.218 H -74.6 -28.6 11.0 0.049 0.169 D:P00492:0.169
 HOH
 2.920
 NH1
 O
ARG D:44 D:44 28.0 0.124 H -65.1 -44.2 0.0 0.0 0.124 C:P00492:0.124
 HOH
 4.713
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ARG A:50 A:44 32.0 0.142 H -69.1 -41.4 1.0 0.004 0.138 B:P00492:0.138
 HOH
 2.874
 NH1
 O
ARG B:50 B:44 32.0 0.142 H -70.6 -42.0 2.0 0.009 0.133 A:P00492:0.133
 HOH
 3.016
 NH1
 O
ARG C:50 C:44 24.0 0.107 H -69.1 -39.4 1.0 0.004 0.103 D:P00492:0.102
 HOH
 2.901
 NH1
 O
ARG D:50 D:44 34.0 0.151 H -67.5 -38.7 3.0 0.013 0.138 C:P00492:0.138
 HOH
 2.935
 NH1
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ARG A:43 A:44 42.0 0.187 H -71.4 -42.2 42.0 0.187 0.0 HOH
 4.323
 N
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ARG A:45 A:44 28.0 0.124 H -67.7 -40.6 1.0 0.004 0.12 B:P00492:0.12
 HOH
 2.823
 NH1
 O
ARG B:45 B:44 31.0 0.138 H -66.5 -43.1 2.0 0.009 0.129 A:P00492:0.129
 HOH
 2.788
 NH1
 O
ARG C:45 C:44 39.0 0.173 H -71.3 -41.3 9.0 0.04 0.133 D:P00492:0.133
 HOH
 2.697
 NH1
 O
ARG D:45 D:44 31.0 0.138 H -67.5 -39.7 2.0 0.009 0.129 C:P00492:0.129
 HOH
 2.758
 NH1
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ARG A:51 A:44 33.0 0.147 H -68.9 -38.2 3.0 0.013 0.134 B:P00492:0.133
 HOH
 2.943
 NH1
 O
ARG B:51 B:44 31.0 0.138 H -69.5 -41.1 2.0 0.009 0.129 A:P00492:0.129
 HOH
 3.071
 NH1
 O
ARG C:51 C:44 36.0 0.16 H -70.4 -40.7 5.0 0.022 0.138 D:P00492:0.138
 HOH
 3.060
 NH1
 O
ARG D:51 D:44 35.0 0.156 H -72.6 -37.7 3.0 0.013 0.143 C:P00492:0.142
 HOH
 3.615
 NH2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ARG A:45 A:44 29.0 0.129 H -69.3 -34.2 1.0 0.004 0.125 C:P00492:0.124
 HOH
 2.881
 NH1
 O
ARG B:45 B:44 28.0 0.124 H -69.7 -44.4 2.0 0.009 0.115 D:P00492:0.116
 HOH
 2.839
 NH1
 O
ARG C:45 C:44 49.0 0.218 H -63.5 -44.1 13.0 0.058 0.16 A:P00492:0.16
 HOH
 2.900
 NH1
 O
ARG D:45 D:44 45.0 0.2 H -71.9 -34.4 10.0 0.044 0.156 B:P00492:0.156
 HOH
 2.915
 NH2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ARG A:45 A:44 43.0 0.191 H -71.0 -37.7 6.0 0.027 0.164 D:P00492:0.164
 HOH
 2.844
 NH1
 O
ARG B:45 B:44 45.0 0.2 H -71.1 -37.5 10.0 0.044 0.156 C:P00492:0.156
 HOH
 2.770
 NH1
 O
ARG C:45 C:44 43.0 0.191 H -75.3 -42.7 7.0 0.031 0.16 B:P00492:0.16
 HOH
 4.495
 N
 O
ARG D:45 D:44 50.0 0.222 H -67.4 -38.5 12.0 0.053 0.169 A:P00492:0.169
 HOH
 4.551
 N
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ARG A:42 A:44 32.0 0.142 H -66.7 -43.0 2.0 0.009 0.133 B:P00492:0.133
 HOH
 3.039
 NH1
 O
ARG B:42 B:44 39.0 0.173 H -68.0 -41.8 8.0 0.036 0.137 A:P00492:0.138
 HOH
 3.093
 NH2
 O
ARG C:42 C:44 44.0 0.196 H -67.0 -41.4 12.0 0.053 0.143 D:P00492:0.142
 HOH
 3.297
 NH2
 O
ARG D:42 D:44 39.0 0.173 H -62.9 -43.6 9.0 0.04 0.133 C:P00492:0.133
 HOH
 3.044
 NH2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ARG A:41 A:44 48.0 0.213 H -59.9 -60.5 48.0 0.213 0.0 HOH
 3.463
 NH2
 O
ARG B:41 B:44 57.0 0.253 H -57.6 -55.8 57.0 0.253 0.0 HOH
 8.990
 NH1
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ARG A:53 A:53 35.0 0.156 H -71.6 -39.2 4.0 0.018 0.138 B:P20035+P00492:0.138
 HOH
 3.916
 NH2
 O
ARG B:53 B:53 22.0 0.098 H -68.8 -47.1 0.0 0.0 0.098 A:P20035+P00492:0.098
 HOH
 4.771
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ARG A:45 A:45 27.0 0.12 H -66.4 -40.5