Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609219 . G A CCDS14641.1:NM_000194.2:c.143cGt>cAt_NP_000185.1:p.48R>H Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ARG A:47 A:47 119.0 0.529 H -67.2 -38.1 37.0 0.164 0.365 C:P00492:0.364
D:P00492:0.004
 HOH
 3.007
 NH2
 O
ARG B:47 B:47 114.0 0.507 H -72.3 -43.8 41.0 0.182 0.325 C:P00492:0.004
D:P00492:0.324
 HOH
 3.353
 CG
 O
ARG C:47 C:47 113.0 0.502 H -74.1 -37.6 41.0 0.182 0.32 A:P00492:0.32
 HOH
 2.925
 NH2
 O
ARG D:47 D:47 111.0 0.493 H -70.7 -36.9 24.0 0.107 0.386 B:P00492:0.387
 HOH
 3.022
 NH2
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ARG A:47 A:47 124.0 0.551 H -53.6 -57.4 35.0 0.156 0.395 B:P00492:0.396
 HOH
 3.252
 NH2
 O
ARG B:47 B:47 113.0 0.502 H -68.1 -38.2 36.0 0.16 0.342 A:P00492:0.342
 HOH
 2.745
 NH2
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ARG A:47 A:47 132.0 0.587 H -71.9 -37.3 49.0 0.218 0.369 B:P00492:0.369
 HOH
 2.946
 NH1
 O
ARG B:47 B:47 135.0 0.6 H -67.9 -38.0 53.0 0.236 0.364 A:P00492:0.364
 HOH
 3.051
 NH1
 O
ARG C:47 C:47 143.0 0.636 H -70.3 -38.2 NA NA NA
ARG D:47 D:47 120.0 0.533 H -68.1 -40.1 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:47 A:47 147.0 0.653 H -64.9 -45.6 56.0 0.249 0.404 B:P00492:0.404
 HOH
 2.664
 NH2
 O
ARG B:47 B:47 95.0 0.422 H -68.9 -39.6 20.0 0.089 0.333 A:P00492:0.333
 HOH
 2.767
 NH2
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:47 A:47 130.0 0.578 H -71.7 -47.7 48.0 0.213 0.365 B:P00492:0.364
 HOH
 2.439
 NH2
 O
ARG B:47 B:47 96.0 0.427 H -57.6 -36.8 21.0 0.093 0.334 A:P00492:0.333
 HOH
 4.501
 CD
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:47 A:47 136.0 0.604 H -68.3 -45.8 53.0 0.236 0.368 B:P00492:0.369
 HOH
 2.419
 NH2
 O
ARG B:47 B:47 99.0 0.44 H -56.6 -39.6 24.0 0.107 0.333 A:P00492:0.333
 HOH
 4.567
 N
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 116.0 0.516 H -69.1 -38.7 44.0 0.196 0.32 B:P00492:0.32
 HOH
 3.021
 NH1
 O
ARG B:47 B:47 119.0 0.529 H -65.0 -37.2 43.0 0.191 0.338 C:P00492:0.004
A:P00492:0.338
 HOH
 3.484
 NH1
 O
ARG C:47 C:47 115.0 0.511 H -70.7 -36.8 40.0 0.178 0.333 D:P00492:0.333
 HOH
 3.019
 NH2
 O
ARG D:47 D:47 108.0 0.48 H -67.7 -40.1 25.0 0.111 0.369 C:P00492:0.369
 HOH
 2.547
 NH2
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 115.0 0.511 H -65.9 -40.6 37.0 0.164 0.347 D:P00492:0.004
B:P00492:0.347
 HOH
 2.953
 NH2
 O
ARG B:47 B:47 123.0 0.547 H -64.4 -40.9 40.0 0.178 0.369 C:P00492:0.004
A:P00492:0.369
 HOH
 3.046
 NH1
 O
ARG C:47 C:47 114.0 0.507 H -63.6 -45.0 34.0 0.151 0.356 D:P00492:0.356
 HOH
 3.578
 CG
 O
ARG D:47 D:47 112.0 0.498 H -62.9 -46.8 30.0 0.133 0.365 C:P00492:0.364
A:P00492:0.004
 HOH
 2.881
 NH2
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 119.0 0.529 H -63.1 -47.9 46.0 0.204 0.325 D:P00492:0.009
B:P00492:0.324
 HOH
 2.235
 HH11
 O
ARG B:47 B:47 147.0 0.653 H -66.2 -42.8 63.0 0.28 0.373 C:P00492:0.013
A:P00492:0.369
 HOH
 2.357
 HH21
 O
ARG C:47 C:47 118.0 0.524 H -63.6 -40.4 35.0 0.156 0.368 D:P00492:0.369
B:P00492:0.004
 HOH
 1.976
 HH21
 O
ARG D:47 D:47 113.0 0.502 H -63.8 -40.9 36.0 0.16 0.342 C:P00492:0.342
 HOH
 1.759
 HH22
 O
ARG E:47 E:47 118.0 0.524 H -69.3 -37.6 NA NA NA
ARG F:47 F:47 119.0 0.529 H -66.9 -41.3 NA NA NA
ARG G:47 G:47 107.0 0.476 H -60.5 -43.9 NA NA NA
ARG H:47 H:47 106.0 0.471 H -65.0 -44.4 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 120.0 0.533 H -65.6 -41.8 48.0 0.213 0.32 B:P00492:0.32
 HOH
 7.582
 CG
 O
ARG B:47 B:47 117.0 0.52 H -67.3 -44.7 42.0 0.187 0.333 C:P00492:0.004
A:P00492:0.333
 HOH
 7.845
 CG
 O
ARG C:47 C:47 121.0 0.538 H -64.6 -38.3 37.0 0.164 0.374 D:P00492:0.373
B:P00492:0.009
ARG D:47 D:47 109.0 0.484 H -69.4 -31.2 37.0 0.164 0.32 C:P00492:0.32
 HOH
 9.752
 N
 O
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 121.0 0.538 H -70.2 -39.3 46.0 0.204 0.334 D:P00492:0.004
B:P00492:0.333
 HOH
 2.874
 NH1
 O
ARG B:47 B:47 120.0 0.533 H -69.7 -35.3 42.0 0.187 0.346 C:P00492:0.004
A:P00492:0.347
 HOH
 2.892
 NH2
 O
ARG C:47 C:47 110.0 0.489 H -71.9 -36.6 30.0 0.133 0.356 D:P00492:0.356
B:P00492:0.004
 HOH
 2.537
 NH2
 O
ARG D:47 D:47 116.0 0.516 H -67.4 -41.6 37.0 0.164 0.352 C:P00492:0.351
 HOH
 2.840
 NH2
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:47 A:47 114.0 0.507 H -61.5 -51.0 37.0 0.164 0.343 D:P00492:0.004
B:P00492:0.342
 HOH
 2.918
 NH2
 O
ARG B:47 B:47 115.0 0.511 H -65.9 -36.3 41.0 0.182 0.329 A:P00492:0.329
 HOH
 2.791
 NH1
 O
ARG C:47 C:47 99.0 0.44 H -63.8 -42.8 33.0 0.147 0.293 D:P00492:0.293
B:P00492:0.004
 HOH
 3.112
 NH1
 O
ARG D:47 D:47 110.0 0.489 H -80.3 -45.4 39.0 0.173 0.316 C:P00492:0.316
 HOH
 2.711
 NH2
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ARG A:53 A:47 116.0 0.516 H -67.2 -35.5 38.0 0.169 0.347 D:P00492:0.004
B:P00492:0.347
 HOH
 2.700
 NH2
 O
ARG B:53 B:47 123.0 0.547 H -73.0 -35.7 42.0 0.187 0.36 C:P00492:0.004
A:P00492:0.36
 HOH
 3.040
 NH1
 O
ARG C:53 C:47 114.0 0.507 H -73.7 -36.6 26.0 0.116 0.391 D:P00492:0.391
B:P00492:0.004
 HOH
 2.966
 NH2
 O
ARG D:53 D:47 112.0 0.498 H -67.4 -40.7 36.0 0.16 0.338 C:P00492:0.338
 HOH
 2.767
 NH2
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ARG A:46 A:47 143.0 0.636 H -65.7 -28.4 143.0 0.636 0.0 HOH
 3.975
 HB2
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ARG A:48 A:47 111.0 0.493 H -65.9 -42.6 37.0 0.164 0.329 D:P00492:0.004
B:P00492:0.329
 HOH
 2.742
 NH2
 O
ARG B:48 B:47 121.0 0.538 H -67.1 -40.3 47.0 0.209 0.329 C:P00492:0.009
A:P00492:0.329
 HOH
 3.097
 NH1
 O
ARG C:48 C:47 119.0 0.529 H -67.9 -42.1 39.0 0.173 0.356 D:P00492:0.356
B:P00492:0.004
 HOH
 2.861
 NH2
 O
ARG D:48 D:47 68.0 0.302 H -68.0 -40.3 5.0 0.022 0.28 A:P00492:0.004
C:P00492:0.28
 HOH
 3.101
 NH1
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ARG A:54 A:47 116.0 0.516 H -66.6 -41.7 41.0 0.182 0.334 D:P00492:0.009
B:P00492:0.333
 HOH
 3.213
 NH2
 O
ARG B:54 B:47 119.0 0.529 H -69.1 -39.1 43.0 0.191 0.338 A:P00492:0.338
C:P00492:0.004
 HOH
 3.153
 NH1
 O
ARG C:54 C:47 121.0 0.538 H -69.4 -41.8 46.0 0.204 0.334 D:P00492:0.333
B:P00492:0.004
 HOH
 3.176
 NH1
 O
ARG D:54 D:47 119.0 0.529 H -68.2 -43.2 42.0 0.187 0.342 A:P00492:0.004
C:P00492:0.342
 HOH
 2.741
 NH2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ARG A:48 A:47 107.0 0.476 H -74.1 -37.5 32.0 0.142 0.334 C:P00492:0.333
 HOH
 2.423
 NH2
 O
ARG B:48 B:47 106.0 0.471 H -71.7 -40.7 39.0 0.173 0.298 D:P00492:0.298
 HOH
 3.700
 CG
 O
ARG C:48 C:47 99.0 0.44 H -63.8 -45.4 36.0 0.16 0.28 A:P00492:0.28
 HOH
 3.507
 NH2
 O
ARG D:48 D:47 102.0 0.453 H -67.5 -41.7 37.0 0.164 0.289 B:P00492:0.289
 HOH
 3.837
 CG
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ARG A:48 A:47 130.0 0.578 H -69.2 -35.8 60.0 0.267 0.311 D:P00492:0.311
 HOH
 3.353
 NE
 O
ARG B:48 B:47 125.0 0.556 H -70.2 -36.1 56.0 0.249 0.307 C:P00492:0.307
 HOH
 2.411
 NH1
 O
ARG C:48 C:47 122.0 0.542 H -69.4 -37.9 40.0 0.178 0.364 B:P00492:0.364
 HOH
 3.918
 NE
 O
ARG D:48 D:47 139.0 0.618 H -69.0 -38.2 53.0 0.236 0.382 A:P00492:0.382
 HOH
 4.700
 NH1
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ARG A:45 A:47 111.0 0.493 H -66.6 -37.9 32.0 0.142 0.351 D:P00492:0.004
B:P00492:0.351
 HOH
 3.087
 NH2
 O
ARG B:45 B:47 114.0 0.507 H -66.6 -38.8 36.0 0.16 0.347 C:P00492:0.004
A:P00492:0.347
 HOH
 3.156
 NH1
 O
ARG C:45 C:47 122.0 0.542 H -65.9 -41.2 39.0 0.173 0.369 D:P00492:0.364
B:P00492:0.013
 HOH
 3.455
 NH2
 O
ARG D:45 D:47 111.0 0.493 H -66.2 -40.3 38.0 0.169 0.324 C:P00492:0.324
A:P00492:0.004
 HOH
 2.530
 NH2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ARG A:44 A:47 102.0 0.453 H -57.6 -58.6 102.0 0.453 0.0 HOH
 3.507
 CB
 O
ARG B:44 B:47 118.0 0.524 H -119.2 -42.4 118.0 0.524 0.0 HOH
 6.306
 NE
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 LYS A:56 A:56 90.0 0.45 H -74.3 -38.6 13.0 0.065 0.385 B:P20035+P00492:0.385
 HOH
 3.470
 CE
 O
LYS B:56 B:56 92.0 0.46 H -68.9 -44.0 21.0 0.105 0.355 A:P20035+P00492:0.355
 HOH
 3.611
 CE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ARG A:48 A:48 130.0 0.578 H -62.3 -42.2