Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609221 . C A CCDS14641.1:NM_000194.2:c.145Ctt>Att_NP_000185.1:p.49L>I Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 LEU A:48 A:48 2.0 0.012 H -59.8 -39.4 2.0 0.012 0.0 HOH
 3.716
 CD1
 O
LEU B:48 B:48 2.0 0.012 H -57.8 -36.4 2.0 0.012 0.0 HOH
 3.776
 CD1
 O
LEU C:48 C:48 2.0 0.012 H -59.0 -39.1 2.0 0.012 0.0 HOH
 3.828
 CD1
 O
LEU D:48 D:48 2.0 0.012 H -62.0 -38.2 2.0 0.012 0.0 HOH
 3.642
 CD1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 LEU A:48 A:48 3.0 0.018 H -44.7 -49.4 3.0 0.018 0.0 HOH
 6.853
 N
 O
LEU B:48 B:48 2.0 0.012 H -52.1 -51.2 2.0 0.012 0.0 HOH
 4.052
 CD2
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 LEU A:48 A:48 1.0 0.006 H -60.2 -37.3 1.0 0.006 0.0 HOH
 3.764
 CD2
 O
LEU B:48 B:48 1.0 0.006 H -61.2 -40.2 1.0 0.006 0.0 HOH
 3.732
 CD2
 O
LEU C:48 C:48 0.0 0.0 H -62.0 -36.8 NA NA NA
LEU D:48 D:48 1.0 0.006 H -59.1 -36.5 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:48 A:48 1.0 0.006 H -50.4 -46.2 1.0 0.006 0.0 HOH
 3.928
 CD2
 O
LEU B:48 B:48 1.0 0.006 H -58.6 -41.4 1.0 0.006 0.0 HOH
 3.835
 CD2
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:48 A:48 2.0 0.012 H -50.1 -44.2 2.0 0.012 0.0 HOH
 4.453
 CD2
 O
LEU B:48 B:48 2.0 0.012 H -60.4 -36.2 2.0 0.012 0.0 HOH
 5.063
 CD2
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:48 A:48 2.0 0.012 H -49.9 -48.7 2.0 0.012 0.0 HOH
 4.426
 CD2
 O
LEU B:48 B:48 1.0 0.006 H -55.2 -44.0 1.0 0.006 0.0 HOH
 4.938
 CD2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 2.0 0.012 H -62.9 -38.8 2.0 0.012 0.0 HOH
 3.284
 CD2
 O
LEU B:48 B:48 3.0 0.018 H -64.8 -34.9 3.0 0.018 0.0 HOH
 6.272
 N
 O
LEU C:48 C:48 3.0 0.018 H -62.9 -37.8 3.0 0.018 0.0 HOH
 3.668
 CD2
 O
LEU D:48 D:48 2.0 0.012 H -59.9 -38.9 2.0 0.012 0.0 HOH
 4.188
 CD2
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 1.0 0.006 H -60.2 -36.6 1.0 0.006 0.0 HOH
 4.045
 CD1
 O
LEU B:48 B:48 2.0 0.012 H -57.6 -43.7 2.0 0.012 0.0 HOH
 3.852
 CD1
 O
LEU C:48 C:48 1.0 0.006 H -53.7 -42.8 1.0 0.006 0.0 HOH
 4.280
 CD1
 O
LEU D:48 D:48 1.0 0.006 H -54.3 -41.0 1.0 0.006 0.0 HOH
 6.109
 C
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 2.0 0.012 H -58.7 -36.5 2.0 0.012 0.0 HOH
 3.075
 HD12
 O
LEU B:48 B:48 2.0 0.012 H -58.3 -40.5 2.0 0.012 0.0 HOH
 2.998
 HD12
 O
LEU C:48 C:48 1.0 0.006 H -59.4 -37.8 1.0 0.006 0.0 HOH
 4.060
 HD12
 O
LEU D:48 D:48 2.0 0.012 H -63.2 -36.3 2.0 0.012 0.0 HOH
 2.997
 HD12
 O
LEU E:48 E:48 1.0 0.006 H -60.4 -38.9 NA NA NA
LEU F:48 F:48 2.0 0.012 H -57.3 -41.3 NA NA NA
LEU G:48 G:48 3.0 0.018 H -57.0 -45.4 NA NA NA
LEU H:48 H:48 2.0 0.012 H -57.6 -41.2 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 1.0 0.006 H -56.7 -40.1 1.0 0.006 0.0 HOH
 4.210
 CD1
 O
LEU B:48 B:48 2.0 0.012 H -54.6 -42.0 2.0 0.012 0.0 HOH
 3.986
 CD2
 O
LEU C:48 C:48 2.0 0.012 H -61.3 -38.7 2.0 0.012 0.0
LEU D:48 D:48 2.0 0.012 H -66.9 -33.7 2.0 0.012 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 1.0 0.006 H -57.2 -41.3 1.0 0.006 0.0 HOH
 4.973
 CD2
 O
LEU B:48 B:48 2.0 0.012 H -63.3 -37.5 2.0 0.012 0.0 HOH
 3.548
 CD2
 O
LEU C:48 C:48 2.0 0.012 H -64.1 -36.5 2.0 0.012 0.0 HOH
 3.657
 CD2
 O
LEU D:48 D:48 1.0 0.006 H -59.3 -39.9 1.0 0.006 0.0 HOH
 3.600
 CD2
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:48 A:48 2.0 0.012 H -45.3 -46.1 2.0 0.012 0.0 HOH
 3.611
 CD1
 O
LEU B:48 B:48 2.0 0.012 H -61.1 -43.1 2.0 0.012 0.0 HOH
 4.923
 CD1
 O
LEU C:48 C:48 1.0 0.006 H -61.6 -40.0 1.0 0.006 0.0 HOH
 4.751
 CD1
 O
LEU D:48 D:48 0.0 0.0 H -50.6 -40.7 0.0 0.0 0.0 HOH
 6.293
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 LEU A:54 A:48 2.0 0.012 H -63.0 -38.8 2.0 0.012 0.0 HOH
 4.065
 CD1
 O
LEU B:54 B:48 2.0 0.012 H -58.5 -42.2 2.0 0.012 0.0 HOH
 4.226
 CD1
 O
LEU C:54 C:48 1.0 0.006 H -59.0 -44.4 1.0 0.006 0.0 HOH
 4.779
 CD1
 O
LEU D:54 D:48 1.0 0.006 H -55.4 -44.3 1.0 0.006 0.0 HOH
 4.099
 CD1
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 LEU A:47 A:48 1.0 0.006 H -66.3 -32.8 1.0 0.006 0.0 HOH
 6.657
 H
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 LEU A:49 A:48 1.0 0.006 H -59.0 -38.6 1.0 0.006 0.0 HOH
 3.664
 CD2
 O
LEU B:49 B:48 1.0 0.006 H -58.9 -41.9 1.0 0.006 0.0 HOH
 3.561
 CD2
 O
LEU C:49 C:48 1.0 0.006 H -55.8 -40.5 1.0 0.006 0.0 HOH
 3.753
 CD2
 O
LEU D:49 D:48 1.0 0.006 H -57.4 -40.0 1.0 0.006 0.0 HOH
 3.821
 CD2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 LEU A:55 A:48 2.0 0.012 H -59.8 -35.7 2.0 0.012 0.0 HOH
 3.743
 CD2
 O
LEU B:55 B:48 2.0 0.012 H -60.7 -37.8 2.0 0.012 0.0 HOH
 4.061
 CD2
 O
LEU C:55 C:48 1.0 0.006 H -61.0 -36.6 1.0 0.006 0.0 HOH
 3.919
 CD2
 O
LEU D:55 D:48 2.0 0.012 H -55.8 -40.2 2.0 0.012 0.0 HOH
 3.890
 CD2
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 LEU A:49 A:48 2.0 0.012 H -65.3 -32.0 2.0 0.012 0.0 HOH
 3.694
 CD2
 O
LEU B:49 B:48 1.0 0.006 H -55.3 -44.0 1.0 0.006 0.0 HOH
 4.276
 CD2
 O
LEU C:49 C:48 2.0 0.012 H -59.9 -32.7 2.0 0.012 0.0 HOH
 4.885
 CD2
 O
LEU D:49 D:48 3.0 0.018 H -60.0 -37.7 3.0 0.018 0.0 HOH
 3.995
 CD2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 LEU A:49 A:48 2.0 0.012 H -60.1 -42.9 2.0 0.012 0.0 HOH
 4.646
 CD2
 O
LEU B:49 B:48 2.0 0.012 H -59.3 -43.6 2.0 0.012 0.0 HOH
 5.468
 CD2
 O
LEU C:49 C:48 1.0 0.006 H -60.2 -44.3 1.0 0.006 0.0 HOH
 7.274
 N
 O
LEU D:49 D:48 1.0 0.006 H -59.3 -34.7 1.0 0.006 0.0 HOH
 7.300
 N
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 LEU A:46 A:48 2.0 0.012 H -62.2 -37.9 2.0 0.012 0.0 HOH
 3.390
 CD2
 O
LEU B:46 B:48 3.0 0.018 H -63.0 -34.6 3.0 0.018 0.0 HOH
 3.984
 CD2
 O
LEU C:46 C:48 3.0 0.018 H -60.1 -37.5 3.0 0.018 0.0 HOH
 3.240
 CD2
 O
LEU D:46 D:48 3.0 0.018 H -59.7 -39.6 3.0 0.018 0.0 HOH
 3.703
 CD2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 LEU A:45 A:48 5.0 0.029 H -37.8 -44.0 5.0 0.029 0.0 HOH
 6.178
 N
 O
LEU B:45 B:48 5.0 0.029 H -52.3 -22.9 5.0 0.029 0.0
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 LEU A:57 A:57 2.0 0.012 H -55.8 -47.2 2.0 0.012 0.0 HOH
 3.483
 CD2
 O
LEU B:57 B:57 0.0 0.0 H -56.6 -38.7 0.0 0.0 0.0 HOH
 5.345
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 LEU A:49 A:49 1.0 0.006 H -60.7 -40.9