Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609227 . C A CCDS14641.1:NM_000194.2:c.151Cga>Aga_NP_000185.1:p.51R>R Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ARG A:50 A:50 133.0 0.591 H -72.0 -30.9 60.0 0.267 0.324 C:P00492:0.182
D:P00492:0.231
 HOH
 3.057
 NH2
 O
ARG B:50 B:50 139.0 0.618 H -70.5 -29.7 64.0 0.284 0.334 C:P00492:0.227
D:P00492:0.191
 HOH
 2.849
 NH2
 O
ARG C:50 C:50 136.0 0.604 H -75.1 -32.4 66.0 0.293 0.311 A:P00492:0.2
B:P00492:0.196
 HOH
 2.828
 NE
 O
ARG D:50 D:50 132.0 0.587 H -68.3 -37.0 61.0 0.271 0.316 A:P00492:0.222
B:P00492:0.178
 HOH
 2.960
 NH1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ARG A:50 A:50 147.0 0.653 H -66.6 -39.5 140.0 0.622 0.031 B:P00492:0.031
 HOH
 3.720
 NE
 O
ARG B:50 B:50 115.0 0.511 H -57.0 -55.3 86.0 0.382 0.129 A:P00492:0.129
 HOH
 2.530
 NH2
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ARG A:50 A:50 94.0 0.418 H -64.0 -41.3 70.0 0.311 0.107 A:P00492:0.031
B:P00492:0.076
 HOH
 2.530
 NE
 O
ARG B:50 B:50 111.0 0.493 H -61.7 -47.3 75.0 0.333 0.16 B:P00492:0.076
A:P00492:0.084
 HOH
 2.668
 NE
 O
ARG C:50 C:50 119.0 0.529 H -67.4 -39.0 NA NA NA
ARG D:50 D:50 128.0 0.569 H -60.2 -47.7 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:50 A:50 126.0 0.56 H -69.9 -37.2 119.0 0.529 0.031 B:P00492:0.031
 HOH
 3.681
 CD
 O
ARG B:50 B:50 136.0 0.604 H -60.8 -46.1 84.0 0.373 0.231 A:P00492:0.231
 HOH
 3.742
 NH2
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:50 A:50 107.0 0.476 H -72.3 -41.1 99.0 0.44 0.036 B:P00492:0.036
 HOH
 2.980
 NH1
 O
ARG B:50 B:50 137.0 0.609 H -61.4 -48.2 83.0 0.369 0.24 A:P00492:0.24
 HOH
 2.497
 CD
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ARG A:50 A:50 104.0 0.462 H -62.8 -47.2 99.0 0.44 0.022 B:P00492:0.022
 HOH
 3.157
 CD
 O
ARG B:50 B:50 135.0 0.6 H -63.0 -44.9 80.0 0.356 0.244 A:P00492:0.244
 HOH
 2.757
 CD
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 134.0 0.596 H -67.9 -38.7 63.0 0.28 0.316 D:P00492:0.236
B:P00492:0.16
 HOH
 2.018
 NH2
 O
ARG B:50 B:50 135.0 0.6 H -68.4 -36.1 62.0 0.276 0.324 C:P00492:0.253
A:P00492:0.156
 HOH
 2.621
 NH2
 O
ARG C:50 C:50 132.0 0.587 H -70.7 -39.0 68.0 0.302 0.285 D:P00492:0.133
B:P00492:0.227
 HOH
 3.468
 NH2
 O
ARG D:50 D:50 134.0 0.596 H -70.2 -40.5 64.0 0.284 0.312 C:P00492:0.156
A:P00492:0.231
 HOH
 3.204
 NH2
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 135.0 0.6 H -65.5 -38.9 50.0 0.222 0.378 D:P00492:0.267
B:P00492:0.196
 HOH
 3.814
 N
 O
ARG B:50 B:50 136.0 0.604 H -67.3 -33.2 65.0 0.289 0.315 C:P00492:0.227
A:P00492:0.164
 HOH
 2.662
 NH2
 O
ARG C:50 C:50 138.0 0.613 H -65.8 -36.8 67.0 0.298 0.315 D:P00492:0.156
B:P00492:0.204
 HOH
 3.837
 N
 O
ARG D:50 D:50 134.0 0.596 H -70.9 -34.0 73.0 0.324 0.272 C:P00492:0.116
A:P00492:0.213
 HOH
 3.189
 NH1
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 118.0 0.524 H -69.9 -37.3 25.0 0.111 0.413 D:P00492:0.267
B:P00492:0.231
 HOH
 1.942
 HH22
 O
ARG B:50 B:50 120.0 0.533 H -70.4 -38.3 31.0 0.138 0.395 C:P00492:0.378
A:P00492:0.058
 HOH
 3.124
 HB2
 O
ARG C:50 C:50 105.0 0.467 H -72.2 -36.6 17.0 0.076 0.391 D:P00492:0.187
B:P00492:0.284
 HOH
 2.040
 HH22
 O
ARG D:50 D:50 128.0 0.569 H -68.5 -39.4 47.0 0.209 0.36 C:P00492:0.173
A:P00492:0.236
 HOH
 1.936
 HH22
 O
ARG E:50 E:50 124.0 0.551 H -72.4 -39.7 NA NA NA
ARG F:50 F:50 134.0 0.596 H -70.9 -37.4 NA NA NA
ARG G:50 G:50 139.0 0.618 H -67.1 -39.4 NA NA NA
ARG H:50 H:50 112.0 0.498 H -71.3 -36.8 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 146.0 0.649 H -67.2 -39.9 48.0 0.213 0.436 D:P00492:0.24
B:P00492:0.253
 HOH
 9.460
 C
 O
ARG B:50 B:50 137.0 0.609 H -73.2 -31.9 57.0 0.253 0.356 C:P00492:0.249
A:P00492:0.191
 HOH
 9.529
 NH1
 O
ARG C:50 C:50 133.0 0.591 H -66.0 -43.0 62.0 0.276 0.315 D:P00492:0.173
B:P00492:0.218
 HOH
 9.482
 NH1
 O
ARG D:50 D:50 103.0 0.458 H -72.2 -25.4 41.0 0.182 0.276 C:P00492:0.111
A:P00492:0.204
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 133.0 0.591 H -67.1 -40.4 59.0 0.262 0.329 D:P00492:0.24
B:P00492:0.16
 HOH
 2.714
 NH2
 O
ARG B:50 B:50 133.0 0.591 H -66.6 -38.5 62.0 0.276 0.315 C:P00492:0.24
A:P00492:0.147
 HOH
 2.813
 NH2
 O
ARG C:50 C:50 137.0 0.609 H -68.2 -41.9 64.0 0.284 0.325 D:P00492:0.178
B:P00492:0.227
 HOH
 2.770
 NH2
 O
ARG D:50 D:50 142.0 0.631 H -69.0 -40.8 65.0 0.289 0.342 A:P00492:0.244
C:P00492:0.173
 HOH
 2.621
 NH2
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ARG A:50 A:50 139.0 0.618 H -73.1 -37.3 59.0 0.262 0.356 D:P00492:0.253
B:P00492:0.169
 HOH
 2.748
 NH2
 O
ARG B:50 B:50 136.0 0.604 H -66.3 -46.0 54.0 0.24 0.364 A:P00492:0.196
C:P00492:0.249
 HOH
 2.313
 NH2
 O
ARG C:50 C:50 135.0 0.6 H -68.0 -33.2 65.0 0.289 0.311 D:P00492:0.156
B:P00492:0.218
 HOH
 2.953
 NH2
 O
ARG D:50 D:50 135.0 0.6 H -74.9 -32.6 58.0 0.258 0.342 C:P00492:0.16
A:P00492:0.244
 HOH
 4.224
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ARG A:56 A:50 128.0 0.569 H -69.8 -33.7 41.0 0.182 0.387 D:P00492:0.289
B:P00492:0.164
 HOH
 2.678
 NH2
 O
ARG B:56 B:50 133.0 0.591 H -68.4 -36.1 58.0 0.258 0.333 C:P00492:0.236
A:P00492:0.173
 HOH
 2.725
 NH2
 O
ARG C:56 C:50 136.0 0.604 H -67.6 -42.3 67.0 0.298 0.306 D:P00492:0.156
B:P00492:0.222
 HOH
 2.784
 NH2
 O
ARG D:56 D:50 139.0 0.618 H -63.6 -42.3 64.0 0.284 0.334 A:P00492:0.24
C:P00492:0.187
 HOH
 2.950
 NH2
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ARG A:49 A:50 126.0 0.56 H -72.4 -47.5 126.0 0.56 0.0 HOH
 5.805
 HH21
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ARG A:51 A:50 106.0 0.471 H -68.7 -39.9 29.0 0.129 0.342 D:P00492:0.231
B:P00492:0.187
 HOH
 2.535
 NH2
 O
ARG B:51 B:50 134.0 0.596 H -69.4 -41.0 65.0 0.289 0.307 C:P00492:0.231
A:P00492:0.151
 HOH
 2.993
 NH2
 O
ARG C:51 C:50 136.0 0.604 H -68.1 -39.7 63.0 0.28 0.324 D:P00492:0.16
B:P00492:0.249
 HOH
 2.728
 O
 O
ARG D:51 D:50 126.0 0.56 H -63.5 -41.7 48.0 0.213 0.347 A:P00492:0.24
C:P00492:0.187
 HOH
 2.886
 NH2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ARG A:57 A:50 132.0 0.587 H -64.2 -44.5 58.0 0.258 0.329 D:P00492:0.24
B:P00492:0.156
 HOH
 3.047
 NH2
 O
ARG B:57 B:50 139.0 0.618 H -67.4 -40.1 66.0 0.293 0.325 A:P00492:0.156
C:P00492:0.244
 HOH
 2.694
 NE
 O
ARG C:57 C:50 135.0 0.6 H -67.9 -44.7 60.0 0.267 0.333 D:P00492:0.16
B:P00492:0.244
 HOH
 3.924
 N
 O
ARG D:57 D:50 136.0 0.604 H -61.9 -44.8 59.0 0.262 0.342 A:P00492:0.249
C:P00492:0.164
 HOH
 2.723
 O
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ARG A:51 A:50 104.0 0.462 H -67.3 -37.2 36.0 0.16 0.302 C:P00492:0.182
B:P00492:0.124
 HOH
 2.674
 NH1
 O
ARG B:51 B:50 134.0 0.596 H -77.6 -35.6 62.0 0.276 0.32 D:P00492:0.147
A:P00492:0.227
 HOH
 2.511
 NE
 O
ARG C:51 C:50 146.0 0.649 H -73.0 -36.2 67.0 0.298 0.351 A:P00492:0.196
D:P00492:0.213
 HOH
 2.734
 NH2
 O
ARG D:51 D:50 107.0 0.476 H -75.4 -34.9 37.0 0.164 0.312 C:P00492:0.231
B:P00492:0.151
 HOH
 2.565
 NH2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ARG A:51 A:50 123.0 0.547 H -69.5 -40.5 91.0 0.404 0.143 D:P00492:0.062
B:P00492:0.084
 HOH
 3.378
 CD
 O
ARG B:51 B:50 104.0 0.462 H -76.5 -34.9 77.0 0.342 0.12 C:P00492:0.071
A:P00492:0.049
 HOH
 3.069
 CZ
 O
ARG C:51 C:50 107.0 0.476 H -73.7 -38.5 77.0 0.342 0.134 D:P00492:0.022
B:P00492:0.111
 HOH
 3.154
 NH1
 O
ARG D:51 D:50 149.0 0.662 H -68.4 -34.0 91.0 0.404 0.258 C:P00492:0.076
A:P00492:0.182
 HOH
 5.710
 NE
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ARG A:48 A:50 116.0 0.516 H -69.1 -34.8 36.0 0.16 0.356 D:P00492:0.271
B:P00492:0.169
 HOH
 3.098
 CD
 O
ARG B:48 B:50 117.0 0.52 H -73.7 -33.5 42.0 0.187 0.333 C:P00492:0.262
A:P00492:0.151
 HOH
 2.794
 NH2
 O
ARG C:48 C:50 133.0 0.591 H -78.2 -31.8 60.0 0.267 0.324 D:P00492:0.142
B:P00492:0.271
 HOH
 2.731
 NH2
 O
ARG D:48 D:50 136.0 0.604 H -67.0 -41.2 65.0 0.289 0.315 C:P00492:0.147
A:P00492:0.244
 HOH
 2.789
 NH2
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ARG A:47 A:50 153.0 0.68 H -71.7 -22.5 153.0 0.68 0.0 HOH
 3.358
 NH2
 O
ARG B:47 B:50 152.0 0.676 T -86.7 28.2 152.0 0.676 0.0 HOH
 2.703
 NH1
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ARG A:59 A:59 133.0 0.591 H -63.3 -41.4 107.0 0.476 0.115 B:P20035+P00492:0.116
 HOH
 4.899
 NH2
 O
ARG B:59 B:59 41.0 NA H -60.4 -46.7 25.0 NA NA A:P20035+P00492:NA
 HOH
 7.429
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ARG A:51 A:51 134.0 0.596 H -65.7 -42.9