Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609246 . T A CCDS14641.1:NM_000194.2:c.170aTg>aAg_NP_000185.1:p.57M>K Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 MET A:56 A:56 6.0 0.032 H -128.5 11.1 6.0 0.032 0.0 HOH
 7.349
 N
 O
MET B:56 B:56 2.0 0.011 H -116.9 3.9 2.0 0.011 0.0 HOH
 6.002
 CA
 O
MET C:56 C:56 5.0 0.027 H -121.1 -3.9 5.0 0.027 0.0 HOH
 8.092
 CA
 O
MET D:56 D:56 9.0 0.049 H -119.5 -4.0 9.0 0.049 0.0 HOH
 9.227
 CE
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 MET A:56 A:56 0.0 0.0 H -88.2 -25.2 0.0 0.0 0.0 HOH
 5.621
 O
 O
MET B:56 B:56 10.0 0.054 H -129.0 -8.0 10.0 0.054 0.0 HOH
 5.183
 O
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 MET A:56 A:56 0.0 0.0 H -117.5 -7.4 0.0 0.0 0.0 HOH
 5.378
 O
 O
MET B:56 B:56 0.0 0.0 H -119.6 2.0 0.0 0.0 0.0 HOH
 3.394
 C
 O
MET C:56 C:56 1.0 0.005 H -123.4 -13.1 NA NA NA
MET D:56 D:56 0.0 0.0 H -109.1 -4.3 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 MET A:56 A:56 3.0 0.016 H -130.0 -5.9 3.0 0.016 0.0 HOH
 5.294
 O
 O
MET B:56 B:56 37.0 0.2 -98.6 360.0 37.0 0.2 0.0 HOH
 7.031
 O
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 MET A:56 A:56 5.0 0.027 H -127.1 -7.8 5.0 0.027 0.0 HOH
 7.975
 CE
 O
MET B:56 B:56 6.0 0.032 -59.5 178.4 6.0 0.032 0.0 HOH
 8.611
 N
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 MET A:56 A:56 5.0 0.027 H -125.4 -6.6 5.0 0.027 0.0 HOH
 7.772
 O
 O
MET B:56 B:56 3.0 0.016 -61.5 177.7 3.0 0.016 0.0 HOH
 8.749
 N
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 0.0 0.0 H -117.6 4.2 0.0 0.0 0.0 HOH
 3.069
 C
 O
MET B:56 B:56 1.0 0.005 H -113.5 -9.2 1.0 0.005 0.0
MET C:56 C:56 0.0 0.0 H -122.0 1.9 0.0 0.0 0.0 HOH
 2.993
 C
 O
MET D:56 D:56 0.0 0.0 H -117.2 -3.3 0.0 0.0 0.0 HOH
 3.233
 C
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 5.0 0.027 H -122.9 -3.3 5.0 0.027 0.0 HOH
 6.841
 O
 O
MET B:56 B:56 7.0 0.038 H -115.1 1.0 7.0 0.038 0.0 HOH
 7.245
 O
 O
MET C:56 C:56 0.0 0.0 H -106.8 10.8 0.0 0.0 0.0 HOH
 7.883
 CE
 O
MET D:56 D:56 0.0 0.0 H -107.7 -7.5 0.0 0.0 0.0
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 0.0 0.0 H -116.0 -7.8 0.0 0.0 0.0 HOH
 2.951
 HA
 O
MET B:56 B:56 0.0 0.0 H -112.0 -8.6 0.0 0.0 0.0 HOH
 2.948
 HA
 O
MET C:56 C:56 0.0 0.0 H -120.1 -2.5 0.0 0.0 0.0 HOH
 3.213
 HA
 O
MET D:56 D:56 0.0 0.0 H -112.3 -7.4 0.0 0.0 0.0 HOH
 2.960
 HA
 O
MET E:56 E:56 0.0 0.0 H -122.0 -0.8 NA NA NA
MET F:56 F:56 1.0 0.005 H -112.5 1.6 NA NA NA
MET G:56 G:56 2.0 0.011 H -128.8 10.1 NA NA NA
MET H:56 H:56 0.0 0.0 H -117.5 -6.3 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 2.0 0.011 H -125.2 1.3 2.0 0.011 0.0
MET B:56 B:56 1.0 0.005 H -126.0 0.4 1.0 0.005 0.0 HOH
 9.960
 SD
 O
MET C:56 C:56 0.0 0.0 H -117.8 2.4 0.0 0.0 0.0
MET D:56 D:56 0.0 0.0 H -121.0 -1.7 0.0 0.0 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 0.0 0.0 H -119.3 -0.0 0.0 0.0 0.0 HOH
 3.402
 C
 O
MET B:56 B:56 4.0 0.022 H -112.0 -4.9 4.0 0.022 0.0 HOH
 9.937
 CG
 O
MET C:56 C:56 2.0 0.011 H -116.5 -0.6 2.0 0.011 0.0 HOH
 9.042
 C
 O
MET D:56 D:56 0.0 0.0 H -118.2 -7.5 0.0 0.0 0.0 HOH
 3.326
 C
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 MET A:56 A:56 0.0 0.0 H -118.0 -9.0 0.0 0.0 0.0 HOH
 7.172
 CE
 O
MET B:56 B:56 2.0 0.011 H -122.9 -13.3 2.0 0.011 0.0
MET C:56 C:56 3.0 0.016 H -126.6 -0.3 3.0 0.016 0.0 HOH
 9.337
 O
 O
MET D:56 D:56 0.0 0.0 H -118.2 0.3 0.0 0.0 0.0 HOH
 6.461
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 MET A:62 A:56 4.0 0.022 H -118.4 2.4 4.0 0.022 0.0 HOH
 7.684
 O
 O
MET B:62 B:56 6.0 0.032 H -126.5 4.3 6.0 0.032 0.0 HOH
 7.381
 O
 O
MET C:62 C:56 0.0 0.0 H -117.3 -5.0 0.0 0.0 0.0 HOH
 3.298
 C
 O
MET D:62 D:56 0.0 0.0 H -112.6 -1.3 0.0 0.0 0.0 HOH
 3.116
 C
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 MET A:55 A:56 5.0 0.027 -150.8 102.2 5.0 0.027 0.0 HOH
 6.978
 O
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 MET A:57 A:56 0.0 0.0 H -118.3 -5.9 0.0 0.0 0.0 HOH
 2.998
 C
 O
MET B:57 B:56 0.0 0.0 H -118.9 -5.6 0.0 0.0 0.0 HOH
 3.160
 C
 O
MET C:57 C:56 0.0 0.0 H -116.0 -7.7 0.0 0.0 0.0 HOH
 3.053
 C
 O
MET D:57 D:56 0.0 0.0 H -117.9 -4.1 0.0 0.0 0.0 HOH
 3.239
 C
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 MET A:63 A:56 0.0 0.0 H -119.8 -9.1 0.0 0.0 0.0 HOH
 3.168
 C
 O
MET B:63 B:56 0.0 0.0 H -117.5 -0.6 0.0 0.0 0.0 HOH
 3.247
 C
 O
MET C:63 C:56 0.0 0.0 H -116.3 -4.4 0.0 0.0 0.0 HOH
 3.235
 C
 O
MET D:63 D:56 0.0 0.0 H -118.7 -5.3 0.0 0.0 0.0 HOH
 3.419
 C
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 MET A:57 A:56 0.0 0.0 H -125.9 -7.6 0.0 0.0 0.0 HOH
 5.262
 C
 O
MET B:57 B:56 0.0 0.0 T -104.2 -10.8 0.0 0.0 0.0 HOH
 5.874
 N
 O
MET C:57 C:56 0.0 0.0 S -117.9 12.9 0.0 0.0 0.0 HOH
 7.896
 N
 O
MET D:57 D:56 0.0 0.0 H -121.2 2.4 0.0 0.0 0.0 HOH
 3.519
 C
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 MET A:57 A:56 0.0 0.0 T -82.8 -33.6 0.0 0.0 0.0 HOH
 6.344
 N
 O
MET B:57 B:56 2.0 0.011 H -131.4 -1.9 2.0 0.011 0.0 HOH
 6.225
 O
 O
MET C:57 C:56 1.0 0.005 T -122.8 -4.5 1.0 0.005 0.0 HOH
 2.796
 O
 O
MET D:57 D:56 4.0 0.022 S -113.1 -178.3 4.0 0.022 0.0 HOH
 4.241
 N
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 MET A:54 A:56 0.0 0.0 H -115.1 -1.7 0.0 0.0 0.0 HOH
 3.538
 C
 O
MET B:54 B:56 0.0 0.0 H -96.2 20.1 0.0 0.0 0.0 HOH
 5.211
 N
 O
MET C:54 C:56 0.0 0.0 H -121.4 -8.5 0.0 0.0 0.0 HOH
 3.363
 C
 O
MET D:54 D:56 0.0 0.0 H -118.5 -1.9 0.0 0.0 0.0 HOH
 3.193
 C
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 MET A:53 A:56 4.0 0.022 S -100.2 91.9 4.0 0.022 0.0 HOH
 7.882
 CE
 O
MET B:53 B:56 3.0 0.016 S -74.7 -9.6 3.0 0.016 0.0 HOH
 9.446
 O
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 MET A:65 A:65 0.0 0.0 H -117.2 -12.0 0.0 0.0 0.0 HOH
 3.548
 O
 O
MET B:65 B:65 0.0 0.0 H -118.7 -5.2 0.0 0.0 0.0 HOH
 3.604
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 MET A:57 A:57 1.0 0.005 H -113.5 -13.8