Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609248 . G A CCDS14641.1:NM_000194.2:c.172Gga>Aga_NP_000185.1:p.58G>R Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 GLY A:57 A:57 9.0 0.12 T -57.6 -26.5 9.0 0.12 0.0 HOH
 6.037
 CA
 O
GLY B:57 B:57 3.0 0.04 T -31.5 -63.9 3.0 0.04 0.0 HOH
 6.638
 N
 O
GLY C:57 C:57 4.0 0.053 T -44.0 -39.1 4.0 0.053 0.0 HOH
 9.805
 N
 O
GLY D:57 D:57 1.0 0.013 T -54.6 -12.9 1.0 0.013 0.0 HOH
 9.668
 CA
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 GLY A:57 A:57 25.0 0.333 T -56.4 151.5 25.0 0.333 0.0 HOH
 6.323
 CA
 O
GLY B:57 B:57 33.0 0.44 T -66.9 165.0 33.0 0.44 0.0 HOH
 4.108
 O
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 GLY A:57 A:57 18.0 0.24 T -67.1 173.9 18.0 0.24 0.0 HOH
 5.758
 CA
 O
GLY B:57 B:57 42.0 0.56 T -68.2 -7.8 42.0 0.56 0.0 HOH
 2.517
 O
 O
GLY C:57 C:57 11.0 0.147 T -63.9 -10.9 NA NA NA
GLY D:57 D:57 34.0 0.453 T -65.4 -3.8 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:57 A:57 25.0 0.333 T -62.8 158.9 25.0 0.333 0.0 HOH
 7.148
 O
 O
GLY B:57 NA:NA DO NA DO DO DO NA NA NA
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:57 A:57 24.0 0.32 -57.6 163.6 24.0 0.32 0.0 HOH
 8.337
 O
 O
GLY B:57 B:57 46.0 0.613 98.4 79.3 46.0 0.613 0.0 HOH
 8.937
 CA
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLY A:57 A:57 28.0 0.373 -52.1 157.5 28.0 0.373 0.0 HOH
 8.152
 O
 O
GLY B:57 B:57 45.0 0.6 92.4 83.7 45.0 0.6 0.0 HOH
 7.354
 C
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 21.0 0.28 T -76.9 -2.9 21.0 0.28 0.0 HOH
 3.298
 N
 O
GLY B:57 B:57 31.0 0.413 T -102.8 140.5 31.0 0.413 0.0 HOH
 9.778
 O
 O
GLY C:57 C:57 25.0 0.333 T -75.2 -4.3 25.0 0.333 0.0 HOH
 3.148
 N
 O
GLY D:57 D:57 19.0 0.253 T -76.1 3.7 19.0 0.253 0.0 HOH
 3.563
 N
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 31.0 0.413 -57.8 151.6 31.0 0.413 0.0 HOH
 7.553
 O
 O
GLY B:57 B:57 26.0 0.347 T -58.6 145.9 26.0 0.347 0.0 HOH
 8.069
 O
 O
GLY C:57 C:57 7.0 0.093 T -59.5 -22.0 7.0 0.093 0.0 HOH
 8.160
 O
 O
GLY D:57 D:57 19.0 0.253 T -72.7 3.1 19.0 0.253 0.0
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 18.0 0.24 T -70.1 -5.6 18.0 0.24 0.0 HOH
 3.431
 N
 O
GLY B:57 B:57 24.0 0.32 T -64.7 168.0 24.0 0.32 0.0 HOH
 2.349
 O
 O
GLY C:57 C:57 17.0 0.227 T -76.6 3.6 17.0 0.227 0.0 HOH
 3.576
 N
 O
GLY D:57 D:57 18.0 0.24 T -80.4 25.8 18.0 0.24 0.0 HOH
 2.853
 O
 O
GLY E:57 E:57 18.0 0.24 T -72.8 -4.1 NA NA NA
GLY F:57 F:57 27.0 0.36 T -56.2 150.8 NA NA NA
GLY G:57 G:57 27.0 0.36 T -84.3 21.1 NA NA NA
GLY H:57 H:57 18.0 0.24 T -70.8 -4.2 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 30.0 0.4 T -77.6 26.0 30.0 0.4 0.0
GLY B:57 B:57 22.0 0.293 T -80.6 26.0 22.0 0.293 0.0
GLY C:57 C:57 25.0 0.333 T -72.0 -3.6 25.0 0.333 0.0
GLY D:57 D:57 12.0 0.16 T -81.2 23.1 12.0 0.16 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 19.0 0.253 T -78.8 4.5 19.0 0.253 0.0 HOH
 3.670
 N
 O
GLY B:57 B:57 28.0 0.373 T -116.2 133.2 28.0 0.373 0.0
GLY C:57 C:57 28.0 0.373 T -65.5 -8.7 28.0 0.373 0.0 HOH
 6.098
 O
 O
GLY D:57 D:57 19.0 0.253 T -71.9 4.7 19.0 0.253 0.0 HOH
 3.630
 N
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLY A:57 A:57 28.0 0.373 T -64.5 173.7 28.0 0.373 0.0
GLY B:57 B:57 8.0 0.107 T -119.1 63.4 8.0 0.107 0.0
GLY C:57 C:57 27.0 0.36 T -78.4 64.0 27.0 0.36 0.0 HOH
 7.903
 O
 O
GLY D:57 D:57 23.0 0.307 T -79.8 2.2 23.0 0.307 0.0 HOH
 7.110
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 GLY A:63 A:57 14.0 0.187 T -45.9 -37.7 14.0 0.187 0.0 HOH
 4.202
 O
 O
GLY B:63 B:57 29.0 0.387 T -61.1 137.9 29.0 0.387 0.0 HOH
 8.341
 O
 O
GLY C:63 C:57 20.0 0.267 T -64.3 -6.5 20.0 0.267 0.0 HOH
 3.662
 N
 O
GLY D:63 D:57 19.0 0.253 T -77.6 5.0 19.0 0.253 0.0 HOH
 3.431
 N
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 GLY A:56 A:57 85.0 1.0 -103.1 13.6 85.0 1.0 0.0 HOH
 7.718
 HA2
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 GLY A:58 A:57 20.0 0.267 T -79.7 9.7 20.0 0.267 0.0 HOH
 2.766
 O
 O
GLY B:58 B:57 23.0 0.307 T -76.0 1.1 23.0 0.307 0.0 HOH
 3.462
 N
 O
GLY C:58 C:57 11.0 0.147 T -78.5 10.7 11.0 0.147 0.0 HOH
 3.317
 N
 O
GLY D:58 D:57 0.0 0.0 T -69.3 0.5 0.0 0.0 0.0 HOH
 3.498
 N
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 GLY A:64 A:57 5.0 0.067 T -71.6 3.1 5.0 0.067 0.0 HOH
 3.522
 N
 O
GLY B:64 B:57 12.0 0.16 T -80.0 2.1 12.0 0.16 0.0 HOH
 3.475
 N
 O
GLY C:64 C:57 16.0 0.213 T -76.9 7.8 16.0 0.213 0.0 HOH
 3.513
 N
 O
GLY D:64 D:57 18.0 0.24 T -75.5 5.6 18.0 0.24 0.0 HOH
 3.672
 N
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 GLY A:58 A:57 23.0 0.307 T -70.7 3.1 23.0 0.307 0.0 HOH
 3.617
 CA
 O
GLY B:58 B:57 20.0 0.267 T -72.2 10.5 20.0 0.267 0.0 HOH
 6.044
 O
 O
GLY C:58 C:57 20.0 0.267 T -79.3 -8.8 20.0 0.267 0.0 HOH
 7.381
 CA
 O
GLY D:58 D:57 22.0 0.293 T -76.5 -3.9 22.0 0.293 0.0 HOH
 3.644
 N
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 GLY A:58 A:57 11.0 0.147 T -69.8 22.1 11.0 0.147 0.0 HOH
 8.213
 N
 O
GLY B:58 B:57 50.0 0.667 T -78.0 20.8 50.0 0.667 0.0 HOH
 6.573
 CA
 O
GLY C:58 C:57 15.0 0.2 -74.3 -152.7 15.0 0.2 0.0 HOH
 3.436
 O
 O
GLY D:58 D:57 35.0 0.467 93.9 -11.1 35.0 0.467 0.0 HOH
 5.343
 CA
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 GLY A:55 A:57 22.0 0.293 T -75.0 0.4 22.0 0.293 0.0 HOH
 3.910
 N
 O
GLY B:55 B:57 35.0 0.467 -94.0 159.7 35.0 0.467 0.0 HOH
 4.486
 O
 O
GLY C:55 C:57 20.0 0.267 T -72.1 0.3 20.0 0.267 0.0 HOH
 3.608
 CA
 O
GLY D:55 D:57 18.0 0.24 T -77.5 1.8 18.0 0.24 0.0 HOH
 3.409
 N
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 GLY A:54 A:57 5.0 0.067 -105.7 -123.6 5.0 0.067 0.0 HOH
 8.566
 C
 O
GLY B:54 B:57 4.0 0.053 T -38.0 -71.7 4.0 0.053 0.0 HOH
 9.691
 O
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 GLY A:66 A:66 13.0 0.173 T -65.7 -3.1 13.0 0.173 0.0 HOH
 4.225
 N
 O
GLY B:66 B:66 21.0 0.28 T -66.4 2.1 21.0 0.28 0.0 HOH
 3.887
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 GLY A:58 A:58 21.0 0.28 T -69.5 6.9