Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609269 . C A CCDS14641.1:NM_000194.2:c.193Ctc>Atc_NP_000185.1:p.65L>I Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 LEU A:64 A:64 2.0 0.012 E -109.9 110.3 2.0 0.012 0.0 HOH
 5.780
 CD1
 O
LEU B:64 B:64 1.0 0.006 E -105.2 110.6 1.0 0.006 0.0 HOH
 6.475
 CD1
 O
LEU C:64 C:64 0.0 0.0 E -109.1 115.7 0.0 0.0 0.0 HOH
 5.625
 CD1
 O
LEU D:64 D:64 0.0 0.0 E -104.4 114.2 0.0 0.0 0.0 HOH
 8.719
 CD1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 LEU A:64 A:64 9.0 0.053 E -108.4 131.6 9.0 0.053 0.0 HOH
 7.109
 O
 O
LEU B:64 B:64 7.0 0.041 E -113.8 138.1 7.0 0.041 0.0
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 LEU A:64 A:64 9.0 0.053 E -96.6 102.9 9.0 0.053 0.0 HOH
 4.202
 CD1
 O
LEU B:64 B:64 10.0 0.059 E -98.5 94.7 10.0 0.059 0.0 HOH
 7.996
 O
 O
LEU C:64 C:64 11.0 0.065 E -97.7 100.2 NA NA NA
LEU D:64 D:64 3.0 0.018 E -97.6 102.4 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:64 A:64 4.0 0.024 E -112.1 111.5 4.0 0.024 0.0 HOH
 6.263
 O
 O
LEU B:64 B:64 0.0 0.0 E -103.3 115.6 0.0 0.0 0.0 HOH
 4.397
 O
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:64 A:64 7.0 0.041 E -104.9 111.9 7.0 0.041 0.0 HOH
 5.950
 O
 O
LEU B:64 B:64 0.0 0.0 E -105.8 116.9 0.0 0.0 0.0 HOH
 8.677
 CD1
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:64 A:64 5.0 0.029 E -107.1 117.5 5.0 0.029 0.0 HOH
 5.883
 O
 O
LEU B:64 B:64 0.0 0.0 E -110.2 110.3 0.0 0.0 0.0 HOH
 5.129
 O
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 4.0 0.024 E -112.6 109.4 4.0 0.024 0.0 MG
HOH
 9.937
6.930
 O
CD1
 MG
O
LEU B:64 B:64 2.0 0.012 E -114.0 112.3 2.0 0.012 0.0 MG
HOH
 9.636
7.979
 O
CD1
 MG
O
LEU C:64 C:64 2.0 0.012 E -108.6 112.3 2.0 0.012 0.0 HOH
 8.982
 O
 O
LEU D:64 D:64 5.0 0.029 E -106.3 113.8 5.0 0.029 0.0 MG
HOH
 9.904
7.883
 O
CD1
 MG
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 1.0 0.006 E -103.4 111.2 1.0 0.006 0.0 MG
HOH
 9.630
4.165
 O
CD1
 MG
O
LEU B:64 B:64 0.0 0.0 E -106.3 107.9 0.0 0.0 0.0 MG
HOH
 9.588
6.822
 O
CD1
 MG
O
LEU C:64 C:64 1.0 0.006 E -106.3 110.4 1.0 0.006 0.0 MG
HOH
 9.463
5.426
 O
CD1
 MG
O
LEU D:64 D:64 5.0 0.029 E -104.9 117.3 5.0 0.029 0.0 MG
HOH
 9.938
8.613
 O
CD1
 MG
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 0.0 0.0 E -110.2 110.9 0.0 0.0 0.0 MG
HOH
 9.580
8.880
 O
HA
 MG
O
LEU B:64 B:64 6.0 0.035 E -98.4 115.9 6.0 0.035 0.0 HOH
 7.489
 O
 O
LEU C:64 C:64 4.0 0.024 E -108.0 112.0 4.0 0.024 0.0 MG
HOH
 9.804
7.684
 O
HD11
 MG
O
LEU D:64 D:64 4.0 0.024 E -109.0 114.4 4.0 0.024 0.0 HOH
 2.795
 HD13
 O
LEU E:64 E:64 1.0 0.006 E -105.4 111.5 NA NA NA
LEU F:64 F:64 11.0 0.065 E -101.1 110.1 NA NA NA
LEU G:64 G:64 4.0 0.024 E -110.2 115.7 NA NA NA
LEU H:64 H:64 0.0 0.0 E -99.9 110.3 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 8.0 0.047 E -105.8 118.0 8.0 0.047 0.0 MG
HOH
 9.842
9.199
 O
O
 MG
O
LEU B:64 B:64 1.0 0.006 E -106.7 109.6 1.0 0.006 0.0 MG
HOH
 9.666
8.717
 O
O
 MG
O
LEU C:64 C:64 2.0 0.012 E -114.9 110.4 2.0 0.012 0.0 MG
 9.907
 O
 MG
LEU D:64 D:64 10.0 0.059 E -101.8 110.4 10.0 0.059 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 0.0 0.0 E -106.7 112.6 0.0 0.0 0.0 MG
HOH
 9.696
6.915
 O
CD1
 MG
O
LEU B:64 B:64 8.0 0.047 E -108.8 115.2 8.0 0.047 0.0 MG
 9.570
 O
 MG
LEU C:64 C:64 1.0 0.006 E -107.7 110.5 1.0 0.006 0.0 MG
HOH
 9.728
8.202
 O
CD1
 MG
O
LEU D:64 D:64 0.0 0.0 E -107.1 113.2 0.0 0.0 0.0 MG
HOH
 9.714
8.533
 O
CD1
 MG
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:64 A:64 0.0 0.0 E -118.1 100.2 0.0 0.0 0.0 HOH
 9.024
 O
 O
LEU B:64 B:64 0.0 0.0 E -108.1 110.4 0.0 0.0 0.0 HOH
 8.928
 O
 O
LEU C:64 C:64 12.0 0.071 E -104.9 124.4 12.0 0.071 0.0 MG
HOH
 9.588
9.634
 O
O
 MG
O
LEU D:64 D:64 0.0 0.0 E -112.1 110.0 0.0 0.0 0.0 HOH
 7.195
 CD1
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 LEU A:70 A:64 3.0 0.018 E -107.2 116.9 3.0 0.018 0.0 MG
HOH
 9.768
8.227
 O
N
 MG
O
LEU B:70 B:64 1.0 0.006 E -114.2 114.2 1.0 0.006 0.0 MG
HOH
 9.719
5.627
 O
CD1
 MG
O
LEU C:70 C:64 2.0 0.012 E -103.7 110.4 2.0 0.012 0.0 MG
HOH
 9.655
4.040
 O
CD1
 MG
O
LEU D:70 D:64 3.0 0.018 E -110.5 116.7 3.0 0.018 0.0 MG
HOH
 9.780
4.659
 O
CD1
 MG
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 LEU A:63 A:64 6.0 0.035 E -85.9 94.9 6.0 0.035 0.0 HOH
 4.231
 HD11
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 LEU A:65 A:64 0.0 0.0 E -109.5 111.0 0.0 0.0 0.0 MG
HOH
 9.813
6.534
 O
CD1
 MG
O
LEU B:65 B:64 2.0 0.012 E -109.9 112.5 2.0 0.012 0.0 MG
 9.629
 O
 MG
LEU C:65 C:64 2.0 0.012 E -109.0 114.3 2.0 0.012 0.0 MG
HOH
 9.639
8.854
 O
O
 MG
O
LEU D:65 D:64 2.0 0.012 E -108.7 114.4 2.0 0.012 0.0 MG
HOH
 9.876
9.010
 O
O
 MG
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 LEU A:71 A:64 0.0 0.0 E -104.0 113.6 0.0 0.0 0.0 MG
HOH
 9.876
8.701
 O
CD1
 MG
O
LEU B:71 B:64 5.0 0.029 E -106.2 118.6 5.0 0.029 0.0 MG
HOH
 9.763
9.057
 O
O
 MG
O
LEU C:71 C:64 4.0 0.024 E -104.3 116.6 4.0 0.024 0.0 MG
HOH
 9.593
8.861
 O
O
 MG
O
LEU D:71 D:64 1.0 0.006 E -111.0 113.0 1.0 0.006 0.0 MG
HOH
 9.707
6.612
 O
CD1
 MG
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 LEU A:65 A:64 2.0 0.012 E -105.6 111.9 2.0 0.012 0.0 MG
HOH
 9.665
8.253
 O
CD1
 MG
O
LEU B:65 B:64 2.0 0.012 E -99.8 116.7 2.0 0.012 0.0 MG
HOH
 9.691
7.957
 O
CD1
 MG
O
LEU C:65 C:64 6.0 0.035 E -108.6 109.3 6.0 0.035 0.0 MG
HOH
 9.840
5.826
 O
CD1
 MG
O
LEU D:65 D:64 7.0 0.041 E -112.1 111.4 7.0 0.041 0.0 MG
HOH
 9.685
8.257
 O
CD1
 MG
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 LEU A:65 A:64 4.0 0.024 E -103.4 125.2 4.0 0.024 0.0 MG
HOH
 9.504
9.761
 O
O
 MG
O
LEU B:65 B:64 4.0 0.024 E -104.1 117.9 4.0 0.024 0.0 MG
HOH
 9.695
7.805
 O
CD2
 MG
O
LEU C:65 C:64 11.0 0.065 E -104.8 122.0 11.0 0.065 0.0 MG
HOH
 9.627
9.777
 O
O
 MG
O
LEU D:65 D:64 5.0 0.029 E -107.6 119.2 5.0 0.029 0.0 MG
HOH
 9.941
8.906
 O
O
 MG
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 LEU A:62 A:64 4.0 0.024 E -107.4 110.5 4.0 0.024 0.0 MG
HOH
 9.749
4.489
 O
CD1
 MG
O
LEU B:62 B:64 3.0 0.018 E -103.8 121.6 3.0 0.018 0.0 MG
HOH
 9.797
6.243
 O
CD2
 MG
O
LEU C:62 C:64 7.0 0.041 E -105.4 116.2 7.0 0.041 0.0 MG
HOH
 9.875
6.937
 O
CD2
 MG
O
LEU D:62 D:64 4.0 0.024 E -103.7 122.2 4.0 0.024 0.0 MG
HOH
 9.851
4.211
 O
CD1
 MG
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 LEU A:61 A:64 1.0 0.006 E -110.1 149.5 1.0 0.006 0.0 HOH
 5.837
 N
 O
LEU B:61 B:64 2.0 0.012 -139.4 131.9 2.0 0.012 0.0 MG
HOH
 9.604
8.603
 O
O
 MG
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 LEU A:73 A:73 4.0 0.024 E -109.8 105.0 4.0 0.024 0.0 HOH
 8.094
 O
 O
LEU B:73 B:73 0.0 0.0 E -95.3 104.0 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 LEU A:65 A:65 0.0 0.0 E -106.7 108.2