Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609309 . T A CCDS14641.1:NM_000194.2:c.233cTg>cAg_NP_000185.1:p.78L>Q Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 LEU A:77 A:77 0.0 0.0 H -62.4 -40.8 0.0 0.0 0.0 HOH
 6.106
 C
 O
LEU B:77 B:77 0.0 0.0 H -60.8 -41.6 0.0 0.0 0.0 HOH
 5.985
 N
 O
LEU C:77 C:77 1.0 0.006 H -62.1 -43.9 1.0 0.006 0.0 HOH
 5.994
 N
 O
LEU D:77 D:77 0.0 0.0 H -66.2 -41.4 0.0 0.0 0.0 HOH
 5.768
 N
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 LEU A:77 A:77 1.0 0.006 H -55.1 -51.0 1.0 0.006 0.0 HOH
 7.668
 CB
 O
LEU B:77 B:77 1.0 0.006 H -80.3 -33.5 1.0 0.006 0.0 HOH
 9.931
 C
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 LEU A:77 A:77 1.0 0.006 H -59.6 -49.1 1.0 0.006 0.0 HOH
 5.825
 N
 O
LEU B:77 B:77 0.0 0.0 H -59.7 -50.9 0.0 0.0 0.0 HOH
 5.894
 N
 O
LEU C:77 C:77 1.0 0.006 H -62.7 -48.9 NA NA NA
LEU D:77 D:77 1.0 0.006 H -62.1 -48.3 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:77 A:77 0.0 0.0 H -62.2 -43.1 0.0 0.0 0.0 HOH
 4.860
 N
 O
LEU B:77 B:77 0.0 0.0 H -57.3 -42.8 0.0 0.0 0.0 HOH
 6.828
 O
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:77 A:77 0.0 0.0 H -57.0 -41.5 0.0 0.0 0.0 HOH
 7.972
 O
 O
LEU B:77 B:77 1.0 0.006 H -53.1 -42.8 1.0 0.006 0.0
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 LEU A:77 A:77 0.0 0.0 H -61.2 -42.2 0.0 0.0 0.0 HOH
 7.823
 O
 O
LEU B:77 B:77 0.0 0.0 H -57.0 -44.3 0.0 0.0 0.0 HOH
 8.452
 CD2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 0.0 0.0 H -64.7 -43.2 0.0 0.0 0.0 HOH
 5.854
 N
 O
LEU B:77 B:77 0.0 0.0 H -61.5 -40.4 0.0 0.0 0.0 HOH
 7.599
 O
 O
LEU C:77 C:77 0.0 0.0 H -60.8 -40.1 0.0 0.0 0.0 HOH
 6.287
 C
 O
LEU D:77 D:77 0.0 0.0 H -63.6 -45.5 0.0 0.0 0.0 HOH
 6.085
 C
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 1.0 0.006 H -62.4 -47.7 1.0 0.006 0.0 HOH
 5.944
 C
 O
LEU B:77 B:77 0.0 0.0 H -63.5 -46.0 0.0 0.0 0.0 HOH
 6.072
 N
 O
LEU C:77 C:77 0.0 0.0 H -54.4 -48.1 0.0 0.0 0.0 HOH
 5.932
 C
 O
LEU D:77 D:77 0.0 0.0 H -58.6 -43.7 0.0 0.0 0.0 HOH
 5.920
 C
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 1.0 0.006 H -58.5 -43.9 1.0 0.006 0.0 HOH
 6.064
 N
 O
LEU B:77 B:77 1.0 0.006 H -56.5 -48.5 1.0 0.006 0.0 HOH
 5.841
 C
 O
LEU C:77 C:77 1.0 0.006 H -55.5 -53.0 1.0 0.006 0.0 HOH
 5.886
 N
 O
LEU D:77 D:77 0.0 0.0 H -58.2 -42.7 0.0 0.0 0.0 HOH
 6.145
 C
 O
LEU E:77 E:77 0.0 0.0 H -59.8 -44.8 NA NA NA
LEU F:77 F:77 1.0 0.006 H -58.1 -45.0 NA NA NA
LEU G:77 G:77 1.0 0.006 H -60.5 -50.0 NA NA NA
LEU H:77 H:77 0.0 0.0 H -59.1 -47.7 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 0.0 0.0 H -62.5 -41.3 0.0 0.0 0.0 HOH
 8.030
 N
 O
LEU B:77 B:77 0.0 0.0 H -62.5 -43.9 0.0 0.0 0.0 HOH
 9.978
 CD1
 O
LEU C:77 C:77 0.0 0.0 H -62.2 -45.0 0.0 0.0 0.0 HOH
 7.974
 O
 O
LEU D:77 D:77 1.0 0.006 H -60.0 -39.4 1.0 0.006 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 0.0 0.0 H -58.9 -43.4 0.0 0.0 0.0 HOH
 5.999
 C
 O
LEU B:77 B:77 0.0 0.0 H -61.8 -44.9 0.0 0.0 0.0 HOH
 6.027
 C
 O
LEU C:77 C:77 1.0 0.006 H -57.5 -46.5 1.0 0.006 0.0 HOH
 6.070
 C
 O
LEU D:77 D:77 0.0 0.0 H -58.3 -45.6 0.0 0.0 0.0 HOH
 5.997
 C
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 LEU A:77 A:77 0.0 0.0 H -54.6 -40.0 0.0 0.0 0.0 HOH
 6.120
 C
 O
LEU B:77 B:77 0.0 0.0 H -52.2 -48.0 0.0 0.0 0.0 HOH
 5.835
 C
 O
LEU C:77 C:77 0.0 0.0 H -59.3 -49.7 0.0 0.0 0.0 HOH
 5.908
 N
 O
LEU D:77 D:77 0.0 0.0 H -57.9 -44.4 0.0 0.0 0.0 HOH
 7.312
 O
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 LEU A:83 A:77 0.0 0.0 H -60.2 -42.6 0.0 0.0 0.0 HOH
 6.105
 C
 O
LEU B:83 B:77 0.0 0.0 H -58.4 -44.7 0.0 0.0 0.0 HOH
 6.033
 C
 O
LEU C:83 C:77 0.0 0.0 H -57.4 -43.0 0.0 0.0 0.0 HOH
 6.011
 C
 O
LEU D:83 D:77 0.0 0.0 H -56.8 -47.1 0.0 0.0 0.0 HOH
 6.038
 C
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 LEU A:76 A:77 0.0 0.0 H -49.9 -52.1 0.0 0.0 0.0 HOH
 7.124
 H
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 LEU A:78 A:77 1.0 0.006 H -63.8 -44.2 1.0 0.006 0.0 HOH
 6.005
 N
 O
LEU B:78 B:77 0.0 0.0 H -62.4 -44.3 0.0 0.0 0.0 HOH
 5.928
 O
 O
LEU C:78 C:77 0.0 0.0 H -58.0 -46.9 0.0 0.0 0.0 HOH
 5.554
 O
 O
LEU D:78 D:77 0.0 0.0 H -57.1 -50.7 0.0 0.0 0.0 HOH
 5.867
 N
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 LEU A:84 A:77 0.0 0.0 H -58.5 -44.1 0.0 0.0 0.0 HOH
 5.975
 N
 O
LEU B:84 B:77 0.0 0.0 H -58.8 -46.7 0.0 0.0 0.0 HOH
 5.878
 N
 O
LEU C:84 C:77 0.0 0.0 H -59.7 -46.3 0.0 0.0 0.0 HOH
 5.745
 N
 O
LEU D:84 D:77 0.0 0.0 H -57.4 -47.4 0.0 0.0 0.0 HOH
 5.957
 C
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 LEU A:78 A:77 0.0 0.0 H -65.3 -44.1 0.0 0.0 0.0 HOH
 6.111
 C
 O
LEU B:78 B:77 3.0 0.018 H -61.5 -38.1 3.0 0.018 0.0 HOH
 5.948
 C
 O
LEU C:78 C:77 1.0 0.006 H -62.3 -36.1 1.0 0.006 0.0 HOH
 5.756
 C
 O
LEU D:78 D:77 1.0 0.006 H -64.0 -43.8 1.0 0.006 0.0 HOH
 5.946
 N
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 LEU A:78 A:77 1.0 0.006 H -61.5 -40.3 1.0 0.006 0.0 HOH
 7.810
 O
 O
LEU B:78 B:77 0.0 0.0 H -62.0 -41.1 0.0 0.0 0.0 HOH
 6.099
 C
 O
LEU C:78 C:77 0.0 0.0 H -61.5 -41.6 0.0 0.0 0.0 HOH
 9.754
 C
 O
LEU D:78 D:77 0.0 0.0 H -62.7 -42.6 0.0 0.0 0.0 HOH
 6.988
 O
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 LEU A:75 A:77 0.0 0.0 H -58.6 -49.3 0.0 0.0 0.0 HOH
 5.690
 N
 O
LEU B:75 B:77 0.0 0.0 H -58.8 -44.2 0.0 0.0 0.0 HOH
 5.597
 O
 O
LEU C:75 C:77 0.0 0.0 H -63.9 -41.7 0.0 0.0 0.0 HOH
 5.779
 N
 O
LEU D:75 D:77 1.0 0.006 H -63.2 -43.3 1.0 0.006 0.0 HOH
 5.735
 O
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 LEU A:74 A:77 1.0 0.006 H -54.4 -22.2 1.0 0.006 0.0 HOH
 8.149
 O
 O
LEU B:74 B:77 3.0 0.018 H -39.2 -40.7 3.0 0.018 0.0 HOH
 8.213
 N
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 LEU A:86 A:86 1.0 0.006 H -59.5 -51.6 1.0 0.006 0.0 HOH
 6.923
 N
 O
LEU B:86 B:86 1.0 0.006 H -49.7 -49.7 1.0 0.006 0.0 HOH
 8.293
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 LEU A:78 A:78 0.0 0.0 H -58.7 -44.8