Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133609315 . A C CCDS14641.1:NM_000194.2:c.239gAt>gCt_NP_000185.1:p.80D>A Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 ASP A:79 A:79 81.0 0.54 H -64.0 -40.1 38.0 0.253 0.287 B:P00492:0.287
 HOH
 2.718
 O
 O
ASP B:79 B:79 76.0 0.507 H -67.7 -42.0 37.0 0.247 0.26 A:P00492:0.26
 HOH
 2.513
 OD2
 O
ASP C:79 C:79 76.0 0.507 H -67.3 -37.0 37.0 0.247 0.26 D:P00492:0.26
 HOH
 2.613
 O
 O
ASP D:79 D:79 78.0 0.52 H -60.2 -45.8 37.0 0.247 0.273 C:P00492:0.273
 HOH
 2.676
 O
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 ASP A:79 A:79 86.0 0.573 H -64.3 -33.4 46.0 0.307 0.266 B:P00492:0.267
 HOH
 5.936
 OD1
 O
ASP B:79 B:79 87.0 0.58 H -59.0 -36.4 46.0 0.307 0.273 A:P00492:0.273
 HOH
 4.403
 OD2
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 ASP A:79 A:79 77.0 0.513 H -62.2 -44.8 36.0 0.24 0.273 B:P00492:0.273
 HOH
 2.578
 OD2
 O
ASP B:79 B:79 82.0 0.547 H -64.1 -43.1 44.0 0.293 0.254 A:P00492:0.253
 HOH
 2.614
 OD2
 O
ASP C:79 C:79 86.0 0.573 H -60.1 -45.1 NA NA NA
ASP D:79 D:79 82.0 0.547 H -59.1 -48.6 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:79 A:79 91.0 0.607 H -54.9 -44.0 52.0 0.347 0.26 B:P00492:0.26
 HOH
 4.176
 OD1
 O
ASP B:79 B:79 79.0 0.527 H -55.3 -49.6 43.0 0.287 0.24 A:P00492:0.24
 HOH
 5.223
 OD1
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:79 A:79 90.0 0.6 H -61.8 -47.7 52.0 0.347 0.253 B:P00492:0.253
 HOH
 5.584
 OD1
 O
ASP B:79 B:79 88.0 0.587 H -60.6 -42.7 54.0 0.36 0.227 A:P00492:0.227
 HOH
 4.560
 OD2
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 ASP A:79 A:79 91.0 0.607 H -68.2 -42.3 52.0 0.347 0.26 B:P00492:0.26
 HOH
 5.829
 OD1
 O
ASP B:79 B:79 87.0 0.58 H -60.7 -43.0 52.0 0.347 0.233 A:P00492:0.233
 HOH
 4.346
 OD2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 82.0 0.547 H -63.1 -43.9 43.0 0.287 0.26 C:P00492:0.26
 HOH
 2.623
 OD2
 O
ASP B:79 B:79 76.0 0.507 H -64.8 -39.8 39.0 0.26 0.247 D:P00492:0.247
 HOH
 2.496
 O
 O
ASP C:79 C:79 79.0 0.527 H -68.3 -37.8 34.0 0.227 0.3 A:P00492:0.3
 HOH
 2.433
 O
 O
ASP D:79 D:79 80.0 0.533 H -62.2 -41.9 41.0 0.273 0.26 B:P00492:0.26
 HOH
 2.530
 OD1
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 77.0 0.513 H -62.5 -38.8 35.0 0.233 0.28 C:P00492:0.28
 HOH
 2.600
 O
 O
ASP B:79 B:79 81.0 0.54 H -63.7 -39.5 38.0 0.253 0.287 D:P00492:0.287
 HOH
 2.618
 O
 O
ASP C:79 C:79 76.0 0.507 H -58.4 -42.8 37.0 0.247 0.26 A:P00492:0.26
 HOH
 2.609
 O
 O
ASP D:79 D:79 79.0 0.527 H -65.6 -44.7 41.0 0.273 0.254 B:P00492:0.253
 HOH
 2.638
 OD1
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 80.0 0.533 H -64.7 -37.4 42.0 0.28 0.253 C:P00492:0.253
 HOH
 2.541
 OD2
 O
ASP B:79 B:79 77.0 0.513 H -64.9 -38.7 40.0 0.267 0.246 D:P00492:0.247
 HOH
 2.726
 O
 O
ASP C:79 C:79 80.0 0.533 H -60.6 -43.1 41.0 0.273 0.26 A:P00492:0.26
 HOH
 2.631
 OD2
 O
ASP D:79 D:79 78.0 0.52 H -63.0 -38.4 43.0 0.287 0.233 B:P00492:0.233
 HOH
 2.703
 O
 O
ASP E:79 E:79 77.0 0.513 H -62.8 -43.3 NA NA NA
ASP F:79 F:79 80.0 0.533 H -62.3 -38.3 NA NA NA
ASP G:79 G:79 78.0 0.52 H -62.8 -41.4 NA NA NA
ASP H:79 H:79 80.0 0.533 H -60.7 -39.7 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 76.0 0.507 H -58.0 -41.3 38.0 0.253 0.254 C:P00492:0.253
 HOH
 7.076
 OD2
 O
ASP B:79 B:79 78.0 0.52 H -64.7 -37.0 36.0 0.24 0.28 D:P00492:0.28
 HOH
 7.114
 O
 O
ASP C:79 C:79 83.0 0.553 H -63.2 -45.7 40.0 0.267 0.286 A:P00492:0.287
 HOH
 3.063
 O
 O
ASP D:79 D:79 77.0 0.513 H -60.5 -39.8 39.0 0.26 0.253 B:P00492:0.253
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 82.0 0.547 H -63.2 -39.2 44.0 0.293 0.254 C:P00492:0.253
 HOH
 2.835
 O
 O
ASP B:79 B:79 78.0 0.52 H -65.6 -39.4 34.0 0.227 0.293 D:P00492:0.293
 HOH
 2.885
 O
 O
ASP C:79 C:79 80.0 0.533 H -62.0 -39.8 36.0 0.24 0.293 A:P00492:0.293
 HOH
 2.721
 O
 O
ASP D:79 D:79 82.0 0.547 H -65.1 -38.2 43.0 0.287 0.26 B:P00492:0.26
 HOH
 2.743
 OD1
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 ASP A:79 A:79 85.0 0.567 H -71.6 -40.5 42.0 0.28 0.287 C:P00492:0.287
 HOH
 2.566
 OD1
 O
ASP B:79 B:79 81.0 0.54 H -64.8 -43.3 38.0 0.253 0.287 D:P00492:0.287
 HOH
 2.890
 OD1
 O
ASP C:79 C:79 81.0 0.54 H -63.5 -43.5 42.0 0.28 0.26 A:P00492:0.26
 HOH
 2.887
 OD1
 O
ASP D:79 D:79 83.0 0.553 H -56.7 -41.3 45.0 0.3 0.253 B:P00492:0.253
 HOH
 2.611
 O
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 ASP A:85 A:79 80.0 0.533 H -65.4 -40.3 37.0 0.247 0.286 C:P00492:0.287
 HOH
 2.802
 O
 O
ASP B:85 B:79 83.0 0.553 H -59.4 -39.6 39.0 0.26 0.293 D:P00492:0.293
 HOH
 2.712
 OD1
 O
ASP C:85 C:79 83.0 0.553 H -58.2 -43.8 39.0 0.26 0.293 A:P00492:0.293
 HOH
 2.768
 O
 O
ASP D:85 D:79 86.0 0.573 H -58.3 -42.0 45.0 0.3 0.273 B:P00492:0.273
 HOH
 2.628
 O
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 ASP A:78 A:79 85.0 0.567 H -67.4 -41.5 85.0 0.567 0.0 HOH
 3.023
 OD2
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 ASP A:80 A:79 83.0 0.553 H -60.0 -42.3 45.0 0.3 0.253 C:P00492:0.253
 HOH
 2.773
 O
 O
ASP B:80 B:79 84.0 0.56 H -65.5 -40.0 45.0 0.3 0.26 D:P00492:0.26
 HOH
 2.784
 O
 O
ASP C:80 C:79 83.0 0.553 H -60.4 -40.1 45.0 0.3 0.253 A:P00492:0.253
 HOH
 2.723
 OD2
 O
ASP D:80 D:79 82.0 0.547 H -61.1 -40.1 44.0 0.293 0.254 B:P00492:0.253
 HOH
 2.702
 O
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 ASP A:86 A:79 79.0 0.527 H -62.2 -38.1 43.0 0.287 0.24 C:P00492:0.24
 HOH
 2.678
 O
 O
ASP B:86 B:79 82.0 0.547 H -64.3 -42.4 42.0 0.28 0.267 D:P00492:0.267
 HOH
 2.734
 O
 O
ASP C:86 C:79 80.0 0.533 H -63.7 -39.8 44.0 0.293 0.24 A:P00492:0.24
 HOH
 2.763
 O
 O
ASP D:86 D:79 80.0 0.533 H -65.9 -38.7 45.0 0.3 0.233 B:P00492:0.233
 HOH
 2.746
 O
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 ASP A:80 A:79 82.0 0.547 H -63.7 -48.3 42.0 0.28 0.267 D:P00492:0.267
 HOH
 2.502
 O
 O
ASP B:80 B:79 81.0 0.54 H -60.4 -41.1 44.0 0.293 0.247 C:P00492:0.247
 HOH
 2.823
 OD1
 O
ASP C:80 C:79 81.0 0.54 H -64.7 -42.1 36.0 0.24 0.3 B:P00492:0.3
 HOH
 2.434
 OD2
 O
ASP D:80 D:79 83.0 0.553 H -62.3 -49.0 44.0 0.293 0.26 A:P00492:0.26
 HOH
 2.580
 O
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 ASP A:80 A:79 85.0 0.567 H -62.3 -44.2 41.0 0.273 0.294 C:P00492:0.293
 HOH
 2.959
 O
 O
ASP B:80 B:79 79.0 0.527 H -64.0 -42.7 41.0 0.273 0.254 D:P00492:0.253
 HOH
 2.690
 OD1
 O
ASP C:80 C:79 81.0 0.54 H -62.4 -40.2 39.0 0.26 0.28 A:P00492:0.28
 HOH
 6.980
 OD1
 O
ASP D:80 D:79 80.0 0.533 H -61.9 -42.1 41.0 0.273 0.26 B:P00492:0.26
 HOH
 5.421
 O
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 ASP A:77 A:79 81.0 0.54 H -63.4 -40.8 34.0 0.227 0.313 C:P00492:0.313
 HOH
 2.723
 OD2
 O
ASP B:77 B:79 81.0 0.54 H -63.8 -41.0 42.0 0.28 0.26 D:P00492:0.26
 HOH
 2.660
 O
 O
ASP C:77 C:79 79.0 0.527 H -60.4 -45.0 36.0 0.24 0.287 A:P00492:0.287
 HOH
 2.487
 OD2
 O
ASP D:77 D:79 81.0 0.54 H -65.5 -47.4 43.0 0.287 0.253 B:P00492:0.253
 HOH
 2.814
 O
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 ASP A:76 A:79 64.0 0.427 H -39.6 -66.7 40.0 0.267 0.16 B:P00492:0.16
 HOH
 4.411
 OD2
 O
ASP B:76 B:79 83.0 0.553 H -64.9 -29.4 32.0 0.213 0.34 A:P00492:0.34
 HOH
 8.067
 OD2
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 ASP A:88 A:88 98.0 0.653 H -56.7 -48.2 98.0 0.653 0.0 HOH
 4.601
 OD2
 O
ASP B:88 B:88 90.0 0.6 H -60.6 -42.2 90.0 0.6 0.0 HOH
 7.722
 OD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 ASP A:80 A:80 79.0 0.527 H -61.4 -43.2