Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133620544 . C A CCDS14641.1:NM_000194.2:c.368tCa>tAa_NP_000185.1:p.123S>* Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 SER A:122 A:122 67.0 0.583 G -70.3 -25.1 67.0 0.583 0.0 HOH
 2.552
 OG
 O
SER B:122 B:122 67.0 0.583 G -66.6 -20.1 67.0 0.583 0.0 HOH
 7.088
 C
 O
SER C:122 C:122 63.0 0.548 G -68.1 -16.0 63.0 0.548 0.0 HOH
 3.121
 O
 O
SER D:122 D:122 68.0 0.591 G -63.6 -26.7 68.0 0.591 0.0 HOH
 8.817
 C
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 SER A:122 A:122 67.0 0.583 T -75.9 -12.0 67.0 0.583 0.0
SER B:122 B:122 67.0 NA T -68.4 -23.6 67.0 NA NA HOH
 6.591
 CB
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 SER A:122 A:122 69.0 0.6 G -57.8 -29.3 69.0 0.6 0.0 HOH
 6.213
 O
 O
SER B:122 B:122 52.0 0.452 -68.7 88.2 52.0 0.452 0.0 HOH
 8.222
 C
 O
SER C:122 C:122 63.0 0.548 G -68.6 -17.3 NA NA NA
SER D:122 D:122 94.0 0.817 G -69.1 -8.5 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:122 A:122 67.0 0.583 G -74.4 3.8 67.0 0.583 0.0 HOH
 4.475
 O
 O
SER B:122 B:122 79.0 NA -72.7 -21.0 79.0 NA NA HOH
 4.292
 N
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:122 A:122 63.0 0.548 G -86.6 0.3 63.0 0.548 0.0 HOH
 4.815
 O
 O
SER B:122 B:122 67.0 NA -67.5 -29.7 65.0 NA NA A:P00492:NA
 HOH
 6.293
 N
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 SER A:122 A:122 68.0 0.591 G -79.5 9.7 68.0 0.591 0.0 HOH
 5.054
 O
 O
SER B:122 B:122 65.0 NA -72.5 -34.9 65.0 NA NA HOH
 6.183
 N
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 74.0 0.643 G -75.4 -19.7 74.0 0.643 0.0 HOH
 7.506
 CA
 O
SER B:122 B:122 66.0 NA G -65.4 -21.2 66.0 NA NA
SER C:122 C:122 61.0 0.53 G -71.4 -11.8 61.0 0.53 0.0
SER D:122 D:122 65.0 0.565 G -65.6 -17.6 65.0 0.565 0.0 HOH
 3.047
 O
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 58.0 0.504 G -63.0 -32.3 58.0 0.504 0.0 HOH
 5.950
 N
 O
SER B:122 B:122 60.0 0.522 G -59.0 -32.0 60.0 0.522 0.0 HOH
 6.024
 N
 O
SER C:122 C:122 83.0 0.722 G -82.2 -8.3 83.0 0.722 0.0 HOH
 7.949
 C
 O
SER D:122 D:122 75.0 0.652 G -75.4 -8.5 75.0 0.652 0.0
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 75.0 0.652 G -65.3 -16.6 75.0 0.652 0.0
SER B:122 B:122 65.0 0.565 G -73.1 -16.4 65.0 0.565 0.0 HOH
 7.132
 H
 O
SER C:122 C:122 73.0 0.635 G -67.3 -15.8 73.0 0.635 0.0 HOH
 4.603
 H
 O
SER D:122 D:122 70.0 0.609 G -70.3 -16.6 70.0 0.609 0.0 HOH
 2.585
 OG
 O
SER E:122 E:122 79.0 0.687 G -66.6 -16.3 NA NA NA
SER F:122 NA:NA DO NA DO DO DO NA NA NA
SER G:122 G:122 78.0 0.678 G -68.7 -8.9 NA NA NA
SER H:122 H:122 59.0 0.513 G -73.1 -16.8 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 80.0 0.696 360.0 -5.4 80.0 0.696 0.0
SER B:122 B:122 77.0 0.67 G -73.3 -19.5 77.0 0.67 0.0
SER C:122 C:122 64.0 0.557 G -68.9 -23.7 64.0 0.557 0.0
SER D:122 NA:NA DO NA DO DO DO NA NA NA
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 90.0 0.783 G -63.3 -9.0 90.0 0.783 0.0 HOH
 6.259
 N
 O
SER B:122 NA:NA DO NA DO DO DO NA NA NA
SER C:122 C:122 59.0 0.513 G -69.1 -14.8 59.0 0.513 0.0 HOH
 9.739
 O
 O
SER D:122 D:122 67.0 0.583 G -67.1 -12.9 67.0 0.583 0.0 HOH
 7.916
 N
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 SER A:122 A:122 87.0 0.757 G -65.8 -10.3 87.0 0.757 0.0
SER B:122 B:122 90.0 0.783 G -77.9 -7.4 90.0 0.783 0.0
SER C:122 C:122 66.0 0.574 G -68.3 -23.7 66.0 0.574 0.0
SER D:122 D:122 71.0 0.617 G -72.6 -16.6 71.0 0.617 0.0 HOH
 5.829
 N
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 SER A:128 A:122 52.0 0.452 G -59.9 -25.4 52.0 0.452 0.0 HOH
 3.453
 O
 O
SER B:128 B:122 57.0 0.496 G -66.1 -20.6 57.0 0.496 0.0 HOH
 6.694
 OG
 O
SER C:128 C:122 64.0 0.557 G -68.2 -21.7 64.0 0.557 0.0 HOH
 2.864
 OG
 O
SER D:128 D:122 63.0 0.548 G -58.0 -21.2 63.0 0.548 0.0 HOH
 3.295
 O
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 SER A:121 NA:NA DO NA DO DO DO NA NA NA
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 SER A:123 A:122 76.0 0.661 T -54.7 -22.8 76.0 0.661 0.0 HOH
 5.923
 O
 O
SER B:123 B:122 60.0 0.522 G -62.7 -20.0 60.0 0.522 0.0 HOH
 3.238
 O
 O
SER C:123 C:122 67.0 0.583 G -59.2 -19.8 67.0 0.583 0.0 HOH
 2.989
 O
 O
SER D:123 D:122 63.0 0.548 G -63.2 -19.5 63.0 0.548 0.0 HOH
 8.102
 C
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 SER A:129 A:122 67.0 0.583 G -63.3 -18.6 67.0 0.583 0.0 HOH
 3.187
 O
 O
SER B:129 B:122 65.0 0.565 G -60.1 -16.4 65.0 0.565 0.0 HOH
 2.834
 O
 O
SER C:129 C:122 67.0 0.583 G -61.5 -19.6 67.0 0.583 0.0 HOH
 3.081
 O
 O
SER D:129 D:122 66.0 0.574 G -64.4 -16.2 66.0 0.574 0.0 HOH
 3.613
 CB
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 SER A:123 A:122 87.0 0.757 G -74.3 -0.2 87.0 0.757 0.0 HOH
 7.041
 O
 O
SER B:123 B:122 82.0 0.713 G -63.9 -10.9 82.0 0.713 0.0 HOH
 3.667
 N
 O
SER C:123 C:122 92.0 NA 360.0 -0.5 92.0 NA NA HOH
 3.543
 CB
 O
SER D:123 D:122 56.0 0.487 G -76.6 -7.4 56.0 0.487 0.0 HOH
 3.319
 O
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 SER A:123 A:122 95.0 0.826 G -76.7 3.7 95.0 0.826 0.0
SER B:123 NA:NA DO NA DO DO DO NA NA NA
SER C:123 C:122 108.0 0.939 360.0 -46.0 108.0 0.939 0.0
SER D:123 D:122 97.0 0.843 G -71.1 -12.7 97.0 0.843 0.0
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 SER A:120 A:122 73.0 0.635 G -66.8 -17.7 73.0 0.635 0.0 HOH
 3.546
 CA
 O
SER B:120 B:122 55.0 NA G -66.8 -14.5 55.0 NA NA HOH
 4.896
 N
 O
SER C:120 C:122 56.0 0.487 G -66.0 -14.3 56.0 0.487 0.0 HOH
 3.517
 O
 O
SER D:120 D:122 62.0 0.539 G -66.0 -14.1 62.0 0.539 0.0 HOH
 3.399
 O
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 SER A:119 A:122 79.0 0.687 S -90.4 19.0 79.0 0.687 0.0 HOH
 7.690
 O
 O
SER B:119 B:122 80.0 0.696 T -47.5 -39.4 80.0 0.696 0.0 HOH
 7.043
 OG
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 SER A:131 A:131 58.0 0.504 G -65.3 -21.9 58.0 0.504 0.0 HOH
 7.740
 O
 O
SER B:131 B:131 67.0 0.583 G -65.6 -30.1 67.0 0.583 0.0 HOH
 2.556
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 SER A:123 A:123 52.0 0.452 G -55.5 -26.9