Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133620546 . A C CCDS14641.1:NM_000194.2:c.370Act>Cct_NP_000185.1:p.124T>P Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 THR A:123 A:123 74.0 0.529 G -74.5 -6.1 74.0 0.529 0.0 HOH
 2.402
 OG1
 O
THR B:123 B:123 82.0 0.586 G -80.4 -9.2 82.0 0.586 0.0 HOH
 2.894
 OG1
 O
THR C:123 C:123 73.0 0.521 G -76.8 -5.1 73.0 0.521 0.0 HOH
 3.351
 O
 O
THR D:123 D:123 74.0 0.529 G -71.9 -4.7 74.0 0.529 0.0 HOH
 4.600
 OG1
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 THR A:123 A:123 75.0 0.536 T -50.8 -42.8 75.0 0.536 0.0 HOH
 8.312
 OG1
 O
THR B:123 B:123 84.0 0.6 T -74.0 -16.2 84.0 0.6 0.0 HOH
 7.665
 O
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 THR A:123 A:123 46.0 0.329 G -71.5 -10.6 46.0 0.329 0.0 HOH
 2.547
 OG1
 O
THR B:123 B:123 109.0 0.779 -107.7 45.9 109.0 0.779 0.0 HOH
 5.716
 OG1
 O
THR C:123 C:123 60.0 0.429 G -76.9 -8.2 NA NA NA
THR D:123 D:123 70.0 0.5 G -77.9 -23.1 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:123 A:123 70.0 0.5 G -77.4 -16.7 70.0 0.5 0.0 HOH
 3.546
 O
 O
THR B:123 B:123 58.0 0.414 T -98.1 62.4 58.0 0.414 0.0 HOH
 4.636
 OG1
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:123 A:123 61.0 0.436 G -67.7 -27.7 61.0 0.436 0.0 HOH
 2.457
 O
 O
THR B:123 B:123 57.0 0.407 T -82.5 41.0 45.0 0.321 0.086 A:P00492:0.086
 HOH
 6.723
 CG2
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 THR A:123 A:123 66.0 0.471 G -76.2 -38.0 66.0 0.471 0.0 HOH
 2.578
 O
 O
THR B:123 B:123 58.0 0.414 T -76.5 53.6 43.0 0.307 0.107 A:P00492:0.107
 HOH
 3.826
 CG2
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 61.0 0.436 G -68.2 -15.7 61.0 0.436 0.0 HOH
 7.458
 OG1
 O
THR B:123 B:123 62.0 0.443 G -66.3 -18.3 62.0 0.443 0.0 HOH
 9.034
 OG1
 O
THR C:123 C:123 54.0 0.386 G -72.5 -10.5 54.0 0.386 0.0 HOH
 9.074
 CB
 O
THR D:123 D:123 56.0 0.4 G -68.7 -15.0 56.0 0.4 0.0 HOH
 2.690
 O
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 69.0 0.493 G -72.1 -8.3 69.0 0.493 0.0 HOH
 4.317
 OG1
 O
THR B:123 B:123 60.0 0.429 G -45.5 -43.9 48.0 0.343 0.086 D:P00492:0.086
 HOH
 5.472
 OG1
 O
THR C:123 C:123 72.0 0.514 G -56.6 -24.3 56.0 0.4 0.114 A:P00492:0.114
 HOH
 3.987
 CG2
 O
THR D:123 D:123 52.0 0.371 G -75.8 -11.2 52.0 0.371 0.0 HOH
 9.255
 OG1
 O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 72.0 0.514 G -89.0 8.8 60.0 0.429 0.085 C:P00492:0.086
 HOH
 6.698
 HG1
 O
THR B:123 B:123 55.0 0.393 G -72.9 -13.9 55.0 0.393 0.0 HOH
 5.951
 O
 O
THR C:123 C:123 66.0 0.471 G -70.9 -19.2 66.0 0.471 0.0 HOH
 6.529
 H
 O
THR D:123 D:123 63.0 0.45 G -72.8 -13.5 63.0 0.45 0.0 HOH
 2.472
 O
 O
THR E:123 E:123 59.0 0.421 G -62.9 -27.1 NA NA NA
THR F:123 F:123 123.0 0.879 360.0 -59.9 NA NA NA
THR G:123 G:123 65.0 0.464 G -81.3 -16.7 NA NA NA
THR H:123 H:123 66.0 0.471 G -63.8 -17.2 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 75.0 0.536 -88.4 -7.3 75.0 0.536 0.0
THR B:123 B:123 78.0 0.557 G -75.4 -10.5 78.0 0.557 0.0
THR C:123 C:123 70.0 0.5 G -74.1 -6.3 70.0 0.5 0.0
THR D:123 NA:NA DO NA DO DO DO NA NA NA
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 56.0 0.4 G -61.2 -12.2 36.0 0.257 0.143 C:P00492:0.143
 3L7
HOH
 9.786
4.906
 CG2
CG2
 OAE
O
THR B:123 B:123 84.0 0.6 360.0 -24.7 82.0 0.586 0.014 D:P00492:0.014
 HOH
 8.037
 CG2
 O
THR C:123 C:123 60.0 0.429 G -67.7 -20.4 60.0 0.429 0.0 HOH
 9.032
 CB
 O
THR D:123 D:123 53.0 0.379 G -69.4 -16.8 53.0 0.379 0.0 HOH
 8.626
 CB
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 THR A:123 A:123 77.0 0.55 G -71.6 -5.0 74.0 0.529 0.021 C:P00492:0.021
THR B:123 B:123 70.0 0.5 G -61.4 -29.7 67.0 0.479 0.021 D:P00492:0.021
 HOH
 7.532
 CG2
 O
THR C:123 C:123 74.0 0.529 G -65.8 12.6 73.0 0.521 0.008 A:P00492:0.007
 HOH
 8.231
 OG1
 O
THR D:123 D:123 54.0 0.386 G -67.0 -8.7 35.0 0.25 0.136 B:P00492:0.136
 HOH
 5.117
 OG1
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 THR A:129 A:123 70.0 0.5 G -75.3 3.1 70.0 0.5 0.0 HOH
 4.021
 C
 O
THR B:129 B:123 53.0 0.379 G -67.6 -11.8 53.0 0.379 0.0 HOH
 2.898
 OG1
 O
THR C:129 C:123 60.0 0.429 G -62.7 -18.4 60.0 0.429 0.0 HOH
 3.864
 CG2
 O
THR D:129 D:123 60.0 0.429 G -71.2 -9.6 60.0 0.429 0.0 HOH
 2.998
 OG1
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 THR A:122 A:123 123.0 0.879 360.0 -60.7 123.0 0.879 0.0 HOH
 2.457
 HG22
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 THR A:124 A:123 47.0 0.336 T -56.4 -12.0 31.0 0.221 0.115 C:P00492:0.114
 WPG
HOH
 9.857
3.215
 CG2
O
 OAG
O
THR B:124 B:123 60.0 0.429 G -66.4 -14.4 60.0 0.429 0.0 HOH
 3.242
 O
 O
THR C:124 C:123 50.0 0.357 G -67.8 -15.9 50.0 0.357 0.0 HOH
 2.575
 O
 O
THR D:124 D:123 57.0 0.407 G -73.0 -8.7 57.0 0.407 0.0 HOH
 4.639
 O
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 THR A:130 A:123 48.0 0.343 G -66.8 2.4 28.0 0.2 0.143 C:P00492:0.143
 HOH
 3.895
 C
 O
THR B:130 B:123 57.0 0.407 G -71.3 -15.3 57.0 0.407 0.0 HOH
 2.707
 O
 O
THR C:130 C:123 53.0 0.379 G -64.1 -21.8 53.0 0.379 0.0 HOH
 2.774
 OG1
 O
THR D:130 D:123 56.0 0.4 G -69.0 -12.4 56.0 0.4 0.0 HOH
 2.613
 O
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 THR A:124 A:123 84.0 0.6 G -77.4 -6.8 84.0 0.6 0.0 HOH
 8.365
 OG1
 O
THR B:124 B:123 75.0 0.536 G -83.8 25.3 75.0 0.536 0.0 HOH
 2.347
 OG1
 O
THR C:124 C:123 111.0 0.793 T -86.0 33.7 111.0 0.793 0.0 HOH
 4.208
 CB
 O
THR D:124 D:123 67.0 0.479 G -77.6 -9.7 67.0 0.479 0.0 HOH
 3.258
 O
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 THR A:124 A:123 76.0 0.543 G -68.2 -21.1 76.0 0.543 0.0
THR B:124 B:123 127.0 0.907 360.0 -30.8 127.0 0.907 0.0 HOH
 6.120
 OG1
 O
THR C:124 C:123 79.0 0.564 T -70.6 -18.3 78.0 0.557 0.007 A:P00492:0.007
THR D:124 D:123 60.0 0.429 G -71.7 -14.0 60.0 0.429 0.0 HOH
 9.635
 O
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 THR A:121 A:123 54.0 0.386 G -72.1 -6.7 54.0 0.386 0.0 HOH
 3.226
 OG1
 O
THR B:121 B:123 57.0 0.407 G -69.2 -23.7 57.0 0.407 0.0 HOH
 2.498
 O
 O
THR C:121 C:123 64.0 0.457 G -76.6 -5.5 64.0 0.457 0.0 HOH
 3.358
 O
 O
THR D:121 D:123 57.0 0.407 G -75.8 -7.2 57.0 0.407 0.0 HOH
 3.165
 OG1
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 THR A:120 A:123 70.0 0.5 -131.1 -27.5 70.0 0.5 0.0 HOH
 4.522
 O
 O
THR B:120 B:123 84.0 0.6 T -63.1 -59.7 84.0 0.6 0.0 HOH
 3.922
 OG1
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 THR A:132 A:132 70.0 0.5 G -64.7 -11.2 70.0 0.5 0.0 HOH
 4.817
 OG1
 O
THR B:132 B:132 56.0 0.4 G -88.5 6.1 56.0 0.4 0.0 HOH
 4.276
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 THR A:124 A:124 70.0 0.5 G -63.6 -17.8