Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133624222 . T A CCDS14641.1:NM_000194.2:c.389gTc>gAc_NP_000185.1:p.130V>D Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 VAL A:129 A:129 2.0 0.013 E -106.4 131.9 2.0 0.013 0.0 HOH
 7.362
 CG2
 O
VAL B:129 B:129 1.0 0.006 E -110.4 131.0 1.0 0.006 0.0 HOH
 5.886
 N
 O
VAL C:129 C:129 1.0 0.006 E -111.2 139.3 1.0 0.006 0.0 HOH
 7.590
 N
 O
VAL D:129 D:129 0.0 0.0 E -102.2 135.0 0.0 0.0 0.0 HOH
 7.924
 CB
 O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 VAL A:129 A:129 0.0 0.0 E -103.2 147.1 0.0 0.0 0.0 HOH
 8.853
 N
 O
VAL B:129 B:129 0.0 0.0 E -106.1 143.2 0.0 0.0 0.0 HOH
 7.712
 N
 O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 VAL A:129 A:129 0.0 0.0 E -89.8 125.0 0.0 0.0 0.0 HOH
 7.382
 CG2
 O
VAL B:129 B:129 0.0 0.0 E -95.9 124.2 0.0 0.0 0.0 HOH
 6.932
 O
 O
VAL C:129 C:129 0.0 0.0 E -89.9 126.6 NA NA NA
VAL D:129 D:129 0.0 0.0 E -95.7 124.5 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 VAL A:129 A:129 0.0 0.0 E -106.1 128.8 0.0 0.0 0.0 HOH
 5.729
 N
 O
VAL B:129 B:129 0.0 0.0 E -102.9 130.8 0.0 0.0 0.0 HOH
 8.180
 CG2
 O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 VAL A:129 A:129 0.0 0.0 E -101.5 125.3 0.0 0.0 0.0 HOH
 7.062
 O
 O
VAL B:129 B:129 0.0 0.0 E -110.6 129.0 0.0 0.0 0.0 HOH
 8.875
 O
 O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 VAL A:129 A:129 0.0 0.0 E -101.4 124.5 0.0 0.0 0.0 HOH
 7.017
 O
 O
VAL B:129 B:129 0.0 0.0 E -105.7 129.7 0.0 0.0 0.0 HOH
 8.495
 O
 O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -92.0 121.9 0.0 0.0 0.0 HOH
 6.974
 O
 O
VAL B:129 B:129 0.0 0.0 E -99.4 118.0 0.0 0.0 0.0
VAL C:129 C:129 0.0 0.0 E -93.1 122.7 0.0 0.0 0.0 HOH
 8.349
 N
 O
VAL D:129 D:129 0.0 0.0 E -86.0 120.5 0.0 0.0 0.0 HOH
 7.112
 O
 O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -118.7 126.7 0.0 0.0 0.0 HOH
 5.308
 N
 O
VAL B:129 B:129 0.0 0.0 E -113.6 133.1 0.0 0.0 0.0 HOH
 7.011
 O
 O
VAL C:129 C:129 0.0 0.0 E -104.4 130.8 0.0 0.0 0.0 HOH
 5.623
 N
 O
VAL D:129 D:129 0.0 0.0 E -95.6 125.0 0.0 0.0 0.0
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -96.7 127.0 0.0 0.0 0.0 HOH
 6.904
 H
 O
VAL B:129 B:129 0.0 0.0 E -98.6 125.4 0.0 0.0 0.0 HOH
 6.821
 H
 O
VAL C:129 C:129 0.0 0.0 E -94.2 121.7 0.0 0.0 0.0 HOH
 6.573
 H
 O
VAL D:129 D:129 0.0 0.0 E -90.9 121.9 0.0 0.0 0.0 HOH
 5.556
 HG13
 O
VAL E:129 E:129 0.0 0.0 E -93.2 128.5 NA NA NA
VAL F:129 F:129 0.0 0.0 E -127.0 129.3 NA NA NA
VAL G:129 G:129 0.0 0.0 E -85.0 134.2 NA NA NA
VAL H:129 H:129 0.0 0.0 E -94.9 123.9 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -107.1 126.3 0.0 0.0 0.0
VAL B:129 B:129 0.0 0.0 E -101.2 122.7 0.0 0.0 0.0 HOH
 8.596
 O
 O
VAL C:129 C:129 0.0 0.0 E -88.0 129.2 0.0 0.0 0.0
VAL D:129 D:129 0.0 0.0 E -107.6 125.3 0.0 0.0 0.0
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -87.8 122.4 0.0 0.0 0.0 HOH
 8.584
 O
 O
VAL B:129 B:129 0.0 0.0 E -105.0 129.4 0.0 0.0 0.0
VAL C:129 C:129 0.0 0.0 E -105.6 129.2 0.0 0.0 0.0 HOH
 9.461
 CG2
 O
VAL D:129 D:129 0.0 0.0 E -93.6 123.1 0.0 0.0 0.0 HOH
 6.918
 O
 O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 VAL A:129 A:129 0.0 0.0 E -90.9 131.8 0.0 0.0 0.0 HOH
 6.748
 O
 O
VAL B:129 B:129 0.0 0.0 E -109.7 134.1 0.0 0.0 0.0
VAL C:129 C:129 0.0 0.0 E -121.0 131.5 0.0 0.0 0.0
VAL D:129 D:129 0.0 0.0 E -103.6 127.4 0.0 0.0 0.0 HOH
 6.955
 O
 O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 VAL A:135 A:129 0.0 0.0 E -114.0 131.4 0.0 0.0 0.0 HOH
 5.608
 N
 O
VAL B:135 B:129 1.0 0.006 E -110.4 134.3 1.0 0.006 0.0 HOH
 5.675
 N
 O
VAL C:135 C:129 0.0 0.0 E -102.3 124.5 0.0 0.0 0.0 HOH
 8.017
 O
 O
VAL D:135 D:129 0.0 0.0 E -99.4 128.2 0.0 0.0 0.0 HOH
 6.899
 O
 O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 VAL A:128 A:129 0.0 0.0 E -100.0 147.7 0.0 0.0 0.0 HOH
 6.973
 HG23
 O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 VAL A:130 A:129 0.0 0.0 E -90.0 121.7 0.0 0.0 0.0 HOH
 6.908
 O
 O
VAL B:130 B:129 0.0 0.0 E -102.9 123.7 0.0 0.0 0.0 HOH
 6.695
 O
 O
VAL C:130 C:129 0.0 0.0 E -100.8 124.9 0.0 0.0 0.0 HOH
 7.137
 O
 O
VAL D:130 D:129 0.0 0.0 E -102.8 125.3 0.0 0.0 0.0 HOH
 8.533
 CG2
 O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 VAL A:136 A:129 0.0 0.0 E -92.0 122.5 0.0 0.0 0.0 HOH
 6.972
 O
 O
VAL B:136 B:129 0.0 0.0 E -100.6 123.4 0.0 0.0 0.0 HOH
 6.986
 O
 O
VAL C:136 C:129 0.0 0.0 E -96.1 123.6 0.0 0.0 0.0 HOH
 7.118
 CG1
 O
VAL D:136 D:129 0.0 0.0 E -93.8 122.9 0.0 0.0 0.0 HOH
 6.990
 O
 O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 VAL A:130 A:129 0.0 0.0 E -90.3 123.0 0.0 0.0 0.0 HOH
 9.646
 O
 O
VAL B:130 B:129 0.0 0.0 E -95.5 119.7 0.0 0.0 0.0 HOH
 9.372
 CG2
 O
VAL C:130 C:129 0.0 0.0 E -93.9 122.4 0.0 0.0 0.0 HOH
 8.430
 O
 O
VAL D:130 D:129 0.0 0.0 E -94.3 126.2 0.0 0.0 0.0 HOH
 8.154
 CG2
 O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 VAL A:130 A:129 0.0 0.0 E -89.2 131.2 0.0 0.0 0.0
VAL B:130 B:129 0.0 0.0 E -93.2 129.2 0.0 0.0 0.0 HOH
 6.654
 N
 O
VAL C:130 C:129 0.0 0.0 E -88.7 124.2 0.0 0.0 0.0 HOH
 7.303
 N
 O
VAL D:130 D:129 0.0 0.0 E -97.1 120.1 0.0 0.0 0.0 HOH
 9.015
 N
 O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 VAL A:127 A:129 0.0 0.0 E -97.6 122.9 0.0 0.0 0.0 HOH
 6.672
 O
 O
VAL B:127 B:129 0.0 0.0 E -92.7 119.6 0.0 0.0 0.0 HOH
 7.168
 O
 O
VAL C:127 C:129 0.0 0.0 E -97.8 128.2 0.0 0.0 0.0 HOH
 7.212
 O
 O
VAL D:127 D:129 0.0 0.0 E -90.4 123.3 0.0 0.0 0.0 HOH
 6.876
 CG1
 O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 VAL A:126 A:129 0.0 0.0 E -66.6 -168.5 0.0 0.0 0.0 HOH
 6.549
 O
 O
VAL B:126 B:129 2.0 0.013 E -119.6 139.6 2.0 0.013 0.0 HOH
 8.909
 CG2
 O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 VAL A:138 A:138 0.0 0.0 E -96.5 130.7 0.0 0.0 0.0 HOH
 8.134
 O
 O
VAL B:138 B:138 0.0 0.0 E -98.2 126.1 0.0 0.0 0.0 HOH
 9.826
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 VAL A:130 A:130 0.0 0.0 E -99.3 124.5