wupsivus

Variant

Genome	Chromosome	Position	VCF ID	Ref	Alt	mRNA Change	mRNA Info
GRCh37	chrX	133627538	.	G	A	CCDS14641.1:NM_000194.2:c.403Gat>Aat_NP_000185.1:p.135D>N	Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.

pdb_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

alphafold_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

PDB

Entity							Residue			Monomer					BioUnit				Ligand				View
PDB	Entity	Uniprot	Identity	Evalue	ExpMethod	Date	Name	Label	Auth	ASA	rASA	SS	φ	ψ	ASA	rASA	ΔASA	Interaction	Name	Distance	Atom(p)	Atom(l)	View
1bzy	1	P00492	100.0	3e-161	X-RAY	1999-06-22	ASP	A:134	A:134	22.0	0.147	E	-80.3	-48.6	22.0	0.147	0.0		MG MG IMU POP HOH	3.774 5.661 2.457 4.221 3.449	OD2 OD2 OD2 OD2 OD2	MG MG O2' O2 O
							ASP	B:134	B:134	21.0	0.14	E	-76.7	-50.5	21.0	0.14	0.0		MG MG IMU POP HOH	3.959 5.610 2.426 4.182 3.586	OD2 OD2 OD2 OD2 OD1	MG MG O2' O2 O
							ASP	C:134	C:134	22.0	0.147	E	-77.3	-51.7	22.0	0.147	0.0		MG MG IMU POP HOH	3.922 5.561 2.482 4.119 3.430	OD2 OD2 OD2 OD2 OD1	MG MG O2' O2 O
							ASP	D:134	D:134	21.0	0.14	E	-77.6	-46.8	21.0	0.14	0.0		MG MG IMU POP HOH	4.047 5.781 2.533 4.380 3.354	OD2 OD2 OD2 OD2 OD1	MG MG O2' O2 O
1hmp	1	P00492	100.0	3e-161	X-RAY	1995-06-03	ASP	A:134	A:134	24.0	0.16	E	-94.2	-51.3	24.0	0.16	0.0		5GP HOH	3.692 3.734	OD1 N	O3' O
1hmp	1	P00492	100.0	3e-161	X-RAY	1995-06-03	ASP	B:134	B:134	6.0	0.04	E	-91.4	-57.9	6.0	0.04	0.0		5GP HOH	4.751 7.577	OD1 OD2	O3' O
1z7g	1	P00492	100.0	3e-161	X-RAY	2005-08-02	ASP	A:134	A:134	3.0	0.02	E	-78.0	-42.0	3.0	0.02	0.0		HOH	2.641	OD2	O
							ASP	B:134	B:134	3.0	0.02	E	-78.5	-45.4	3.0	0.02	0.0		HOH	2.567	OD1	O
							ASP	C:134	C:134	2.0	0.013	E	-76.0	-41.1	NA	NA	NA
							ASP	D:134	D:134	4.0	0.027	E	-81.5	-40.3	NA	NA	NA
3gep	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	A:134	A:134	24.0	0.16	E	-91.3	-39.5	24.0	0.16	0.0		24H HOH	5.420 3.175	OD1 OD2	CAH O
3gep	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	B:134	B:134	22.0	0.147	E	-96.3	-42.8	22.0	0.147	0.0		24H HOH	6.943 2.548	CB OD2	CAH O
3ggc	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	A:134	A:134	11.0	0.073	E	-90.2	-39.5	11.0	0.073	0.0		H26 HOH	6.095 3.028	OD1 OD2	CAG O
3ggc	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	B:134	B:134	25.0	0.167	E	-84.5	-49.1	25.0	0.167	0.0		H26 HOH	6.697 2.805	CB OD1	OAN O
3ggj	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	A:134	A:134	11.0	0.073	E	-95.9	-43.0	11.0	0.073	0.0		25H HOH	6.001 2.894	OD1 OD2	OAN O
3ggj	1	P00492	100.0	3e-161	X-RAY	2009-08-18	ASP	B:134	B:134	23.0	0.153	E	-96.4	-46.8	23.0	0.153	0.0		25H HOH	6.952 2.843	CB OD1	OAN O
4rab	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	21.0	0.14	E	-76.2	-49.0	21.0	0.14	0.0		3L3 MG PO4 HOH	5.262 2.228 3.902 2.721	OD1 OD1 OD2 OD2	OAU MG O1 O
							ASP	B:134	B:134	22.0	0.147	E	-79.9	-44.8	22.0	0.147	0.0		3L3 MG PO4 HOH	5.046 2.203 4.101 4.529	OD1 OD1 OD2 CB	OAU MG O4 O
							ASP	C:134	C:134	23.0	0.153	E	-83.4	-41.9	23.0	0.153	0.0		3L3 MG MG PO4 HOH	5.246 2.142 6.348 4.193 2.824	OD1 OD1 OD2 OD2 OD1	CAJ MG MG O2 O
							ASP	D:134	D:134	22.0	0.147	E	-83.0	-45.1	22.0	0.147	0.0		3L3 MG MG PO4 HOH	5.416 2.055 6.667 4.516 2.884	OD1 OD1 OD2 OD2 OD1	OAU MG MG O2 O
4rac	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	22.0	0.147	E	-75.3	-49.0	22.0	0.147	0.0		3L4 MG MG HOH	3.807 6.084 2.136 2.645	OD2 OD2 OD1 OD2	OAD MG MG O
							ASP	B:134	B:134	22.0	0.147	E	-80.5	-43.9	22.0	0.147	0.0		3L4 MG MG HOH	3.779 6.164 2.096 2.713	OD2 OD2 OD1 OD2	OAD MG MG O
							ASP	C:134	C:134	23.0	0.153	E	-79.8	-44.2	23.0	0.153	0.0		3L4 MG MG HOH	3.722 2.245 6.366 2.596	OD2 OD1 OD2 OD2	OAG MG MG O
							ASP	D:134	D:134	24.0	0.16	E	-77.6	-46.8	24.0	0.16	0.0		3L4 MG HOH	4.074 2.115 2.454	OD2 OD1 OD2	OAH MG O
4rad	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	31.0	0.207	E	-83.8	-43.5	31.0	0.207	0.0		3L5 MG HOH	3.445 3.756 2.773	OD1 OD1 OD2	H9 MG O
							ASP	B:134	B:134	35.0	0.233	E	-83.1	-50.9	35.0	0.233	0.0		3L5 MG MG HOH	3.406 3.667 6.008 2.368	OD1 OD1 OD2 H	H10 MG MG O
							ASP	C:134	C:134	25.0	0.167	E	-89.4	-46.9	25.0	0.167	0.0		3L5 MG HOH	2.565 2.375 2.739	OD2 OD1 OD1	OAC MG O
							ASP	D:134	D:134	23.0	0.153	E	-84.8	-39.5	23.0	0.153	0.0		3L5 MG HOH	2.312 2.289 2.714	OD2 OD1 OD1	H6 MG O
							ASP	E:134	E:134	31.0	0.207	E	-85.2	-48.0	NA	NA	NA
							ASP	F:134	F:134	30.0	0.2	E	-87.6	-51.7	NA	NA	NA
							ASP	G:134	G:134	22.0	0.147	E	-79.8	-47.6	NA	NA	NA
							ASP	H:134	H:134	25.0	0.167	E	-87.6	-43.1	NA	NA	NA
4ran	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	24.0	0.16	E	-79.4	-45.9	24.0	0.16	0.0		3L6 MG HOH	5.647 2.936 2.795	OD2 OD1 OD1	N2 MG O
							ASP	B:134	B:134	22.0	0.147	E	-78.3	-43.7	22.0	0.147	0.0		3L6 MG HOH	5.313 2.930 2.956	OD2 OD1 OD1	N2 MG O
							ASP	C:134	C:134	20.0	0.133	E	-76.0	-49.1	20.0	0.133	0.0		3L6 MG HOH	5.509 2.860 2.729	OD2 OD1 OD1	N2 MG O
							ASP	D:134	D:134	19.0	0.127	E	-72.6	-46.0	19.0	0.127	0.0		3L6 MG	5.615 2.504	OD1 OD1	CAL MG
4rao	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	22.0	0.147	E	-83.0	-48.0	22.0	0.147	0.0		3L7 MG MG HOH	4.206 2.353 6.327 2.745	OD2 OD1 OD2 OD2	OAE MG MG O
							ASP	B:134	B:134	23.0	0.153	E	-76.7	-45.9	23.0	0.153	0.0		3L7 MG MG HOH	3.775 2.102 6.377 2.627	OD1 OD1 OD2 OD2	CAL MG MG O
							ASP	C:134	C:134	21.0	0.14	E	-80.8	-43.0	21.0	0.14	0.0		3L7 MG MG HOH	4.187 2.259 5.929 2.550	OD2 OD1 OD2 OD2	OAD MG MG O
							ASP	D:134	D:134	22.0	0.147	E	-77.3	-47.6	22.0	0.147	0.0		3L7 MG MG HOH	4.129 2.364 6.079 2.538	OD2 OD1 OD2 OD2	OAB MG MG O
4raq	1	P00492	100.0	3e-161	X-RAY	2015-01-07	ASP	A:134	A:134	24.0	0.16	E	-76.4	-56.4	24.0	0.16	0.0		3L8 MG MG HOH	3.817 6.267 2.459 3.323	OD2 OD2 OD1 OD2	OAC MG MG O
							ASP	B:134	B:134	18.0	0.12	E	-77.7	-43.8	18.0	0.12	0.0		3L8 MG MG HOH	3.577 7.436 2.423 2.857	OD2 OD2 OD1 OD1	OAC MG MG O
							ASP	C:134	C:134	29.0	0.193	E	-69.6	-59.3	29.0	0.193	0.0		3L8 MG MG HOH	3.654 7.735 2.538 2.925	OD2 OD2 OD1 OD1	OAC MG MG O
							ASP	D:134	D:134	18.0	0.12	E	-77.6	-53.9	18.0	0.12	0.0		3L8 MG MG HOH	2.895 2.365 6.175 3.585	OD2 OD1 OD2 OD2	OAC MG MG O
4ijq	1	P00492	100.0	4e-161	X-RAY	2013-03-27	ASP	A:140	A:134	22.0	0.147	E	-74.2	-49.6	22.0	0.147	0.0		SV2 SO4 MG MG HOH	5.157 3.841 2.117 6.164 2.769	OD2 OD2 OD1 OD2 OD2	CAJ O1 MG MG O
							ASP	B:140	B:134	24.0	0.16	E	-80.2	-47.2	24.0	0.16	0.0		SV2 MG SO4 MG HOH	5.202 2.127 3.825 6.121 2.798	OD2 OD1 OD2 OD2 OD2	CAJ MG O4 MG O
							ASP	C:140	C:134	25.0	0.167	E	-81.7	-48.0	25.0	0.167	0.0		SV2 MG MG SO4 HOH	5.396 2.073 8.305 3.806 2.698	OD1 OD1 OD2 OD2 OD2	CAK MG MG O4 O
							ASP	D:140	D:134	23.0	0.153	E	-79.7	-45.6	23.0	0.153	0.0		MG SV2 MG SO4 HOH	6.170 5.290 2.164 3.898 2.784	OD2 OD1 OD1 OD2 OD2	MG CAJ MG O1 O
4kn6	1	P00492	100.0	1e-160	X-RAY	2013-08-14	ASP	A:133	A:134	27.0	0.18	E	-82.5	-49.5	27.0	0.18	0.0		1RP HOH	3.419 2.598	OD1 H	O2' O
6bnj	1	P00492	99.08	6e-160	X-RAY	2017-12-06	ASP	A:135	A:134	24.0	0.16	E	-73.3	-46.2	24.0	0.16	0.0		WPG MG MG HOH	4.113 2.197 5.725 2.667	OD2 OD1 OD2 OD2	OAD MG MG O
							ASP	B:135	B:134	25.0	0.167	E	-76.8	-48.2	25.0	0.167	0.0		WPG MG MG HOH	4.041 2.406 5.839 2.673	OD2 OD1 OD2 OD2	OAG MG MG O
							ASP	C:135	C:134	24.0	0.16	E	-75.7	-43.9	24.0	0.16	0.0		WPG MG MG HOH	3.954 2.061 5.767 2.642	OD2 OD1 OD2 OD2	OAH MG MG O
							ASP	D:135	D:134	24.0	0.16	E	-79.2	-44.9	24.0	0.16	0.0		WPG MG MG HOH	4.078 1.956 5.699 2.535	OD2 OD1 OD2 OD2	OAG MG MG O
5hia	1	P00492	99.08	8e-160	X-RAY	2017-01-18	ASP	A:141	A:134	22.0	0.147	E	-80.4	-46.9	22.0	0.147	0.0		YPG MG MG HOH	4.279 5.824 2.024 2.679	OD2 OD2 OD1 OD2	OAH MG MG O
							ASP	B:141	B:134	22.0	0.147	E	-75.9	-43.1	22.0	0.147	0.0		YPG MG MG HOH	4.227 5.800 2.067 2.594	OD2 OD2 OD1 OD2	OAH MG MG O
							ASP	C:141	C:134	23.0	0.153	E	-75.5	-45.0	23.0	0.153	0.0		YPG MG MG HOH	4.032 5.762 2.054 2.568	OD2 OD2 OD1 OD2	OAH MG MG O
							ASP	D:141	D:134	22.0	0.147	E	-78.5	-44.0	22.0	0.147	0.0		YPG MG MG HOH	4.175 5.807 2.073 2.597	OD2 OD2 OD1 OD2	OAH MG MG O
5brn	1	P00492	98.62	3e-159	X-RAY	2015-10-14	ASP	A:135	A:134	21.0	0.14	E	-79.2	-45.7	21.0	0.14	0.0		MG 4X2 HOH	2.530 4.449 2.663	OD1 OD2 OD2	MG O10 O
							ASP	B:135	B:134	22.0	0.147	E	-79.0	-49.1	22.0	0.147	0.0		MG 4X2 HOH	2.418 3.848 2.645	OD1 OD2 OD2	MG O10 O
							ASP	C:135	C:134	21.0	0.14	E	-74.2	-50.4	21.0	0.14	0.0		MG 4X2 HOH	2.423 3.398 3.060	OD1 OD1 OD1	MG O10 O
							ASP	D:135	D:134	23.0	0.153	E	-78.8	-49.7	23.0	0.153	0.0		MG 4X2 HOH	2.522 3.697 2.694	OD1 OD1 OD2	MG O10 O
5bsk	1	P00492	98.62	3e-159	X-RAY	2015-09-23	ASP	A:135	A:134	8.0	0.053	E	-79.3	-51.4	8.0	0.053	0.0		4X7 MG HOH	4.078 2.186 2.416	OD2 OD1 OD2	OAD MG O
							ASP	B:135	B:134	7.0	0.047	E	-90.0	-38.1	7.0	0.047	0.0		4X7 MG HOH	5.012 2.290 2.781	OD2 OD1 OD2	OAD MG O
							ASP	C:135	C:134	12.0	0.08	E	-85.7	-44.3	12.0	0.08	0.0		4X7 MG HOH	4.634 2.294 2.766	OD2 OD1 OD2	OAD MG O
							ASP	D:135	D:134	11.0	0.073	E	-87.7	-44.4	11.0	0.073	0.0		4X7 MG HOH	3.522 2.398 2.527	OD2 OD1 OD2	OAD MG O
5w8v	1	P00492	100.0	7e-159	X-RAY	2017-08-30	ASP	A:132	A:134	22.0	0.147	E	-85.5	-43.8	22.0	0.147	0.0		9YP MG HOH	5.352 2.142 2.652	OD2 OD1 OD2	OAE MG O
							ASP	B:132	B:134	25.0	0.167	E	-87.3	-45.0	25.0	0.167	0.0		9YP MG HOH	4.939 2.093 2.525	OD2 OD1 OD2	CAM MG O
							ASP	C:132	C:134	28.0	0.187	E	-84.4	-45.2	28.0	0.187	0.0		9YP MG HOH	4.757 2.141 2.709	OD2 OD1 OD2	OAC MG O
							ASP	D:132	D:134	25.0	0.167	E	-89.2	-39.4	25.0	0.167	0.0		9YP MG HOH	5.487 2.128 2.876	OD2 OD1 OD2	NAA MG O
1d6n	1	P00492	99.07	6e-157	X-RAY	1999-12-30	ASP	A:131	A:134	32.0	0.213	E	-62.4	-26.5	32.0	0.213	0.0		MG PPO PRP HOH	2.732 6.249 2.378 2.664	OD2 OD1 OD2 OD2	MG N3 O2B O
1d6n	1	P00492	99.07	6e-157	X-RAY	1999-12-30	ASP	B:131	B:134	21.0	0.14	S	-28.4	-82.6	21.0	0.14	0.0		MG PPO PRP HOH	2.838 6.397 3.022 3.217	OD2 OD1 OD2 OD2	MG N3 O2 O
2vfa	1	P20035,P00492	80.48	3e-122	X-RAY	2008-06-17	ASP	A:143	A:143	3.0	0.02	E	-84.1	-31.2	3.0	0.02	0.0		5GP SO4 HOH	6.445 7.309 2.777	OD1 OD1 OD1	O2' O1 O
2vfa	1	P20035,P00492	80.48	3e-122	X-RAY	2008-06-17	ASP	B:143	B:143	4.0	0.027	E	-63.6	-58.8	4.0	0.027	0.0		5GP SO4 HOH	5.856 7.896 8.594	OD1 N OD1	O2' O4 O

AlphaFold DB

Entity					Residue			Monomer					View
ID	Entity	Uniprot	Identity	Evalue	Name	Label	Auth	ASA	rASA	SS	φ	ψ	View
af-p00492-f1	1	P00492	100.0	2e-162	ASP	A:135	A:135	21.0	0.14	E	-72.4	-49.4

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