Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chrX 133627565 . C A CCDS14641.1:NM_000194.2:c.430Cag>Aag_NP_000185.1:p.144Q>K Homo sapiens hypoxanthine phosphoribosyltransferase 1 (HPRT1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1bzy 1 P00492 100.0 3e-161 X-RAY
 1999-06-22 GLN A:143 A:143 100.0 0.556 H -64.6 -47.3 100.0 0.556 0.0 IMU
HOH
 6.633
4.618
 N
OE1
 O2P
O
GLN B:143 B:143 92.0 0.511 H -59.9 -43.4 92.0 0.511 0.0 IMU
HOH
 6.491
2.524
 N
O
 O2P
O
GLN C:143 C:143 95.0 0.528 H -56.9 -51.7 95.0 0.528 0.0 IMU
HOH
 6.609
4.965
 N
N
 O2P
O
GLN D:143 D:143 96.0 0.533 H -64.9 -42.0 96.0 0.533 0.0 IMU
HOH
 6.853
2.703
 N
O
 O3P
O
1hmp 1 P00492 100.0 3e-161 X-RAY
 1995-06-03 GLN A:143 A:143 96.0 0.533 H -59.6 -38.0 96.0 0.533 0.0 5GP
HOH
 6.789
4.878
 N
N
 O3P
O
GLN B:143 B:143 90.0 0.5 H -61.5 -40.5 90.0 0.5 0.0 5GP
HOH
 7.192
7.311
 N
NE2
 O1P
O
1z7g 1 P00492 100.0 3e-161 X-RAY
 2005-08-02 GLN A:143 A:143 111.0 0.617 H -60.3 -36.8 111.0 0.617 0.0 HOH
 3.102
 OE1
 O
GLN B:143 B:143 142.0 0.789 H -63.9 -44.6 142.0 0.789 0.0 HOH
 2.875
 CG
 O
GLN C:143 C:143 85.0 0.472 H -59.4 -39.9 NA NA NA
GLN D:143 D:143 141.0 0.783 H -60.5 -39.6 NA NA NA
3gep 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:143 A:143 84.0 0.467 H -63.0 -35.4 84.0 0.467 0.0 24H
HOH
 7.038
2.500
 N
O
 OAC
O
GLN B:143 B:143 110.0 0.611 H -61.1 -38.1 110.0 0.611 0.0 24H
HOH
 6.985
5.113
 N
N
 OAF
O
3ggc 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:143 A:143 87.0 0.483 H -60.0 -29.3 87.0 0.483 0.0 H26
HOH
 6.982
4.864
 N
N
 OAE
O
GLN B:143 B:143 105.0 0.583 H -56.9 -44.1 105.0 0.583 0.0 H26
HOH
 7.018
4.478
 N
N
 OAC
O
3ggj 1 P00492 100.0 3e-161 X-RAY
 2009-08-18 GLN A:143 A:143 86.0 0.478 H -62.3 -31.8 86.0 0.478 0.0 25H
HOH
 6.876
4.806
 N
N
 OAE
O
GLN B:143 B:143 107.0 0.594 H -64.7 -36.5 107.0 0.594 0.0 25H
HOH
 6.991
5.002
 N
N
 OAE
O
4rab 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 91.0 0.506 H -60.5 -39.8 91.0 0.506 0.0 3L3
MG
HOH
 6.799
9.987
5.066
 N
N
N
 OAF
MG
O
GLN B:143 B:143 79.0 0.439 H -59.2 -39.2 79.0 0.439 0.0 3L3
HOH
 6.787
5.104
 N
N
 OAF
O
GLN C:143 C:143 95.0 0.528 H -52.1 -49.3 95.0 0.528 0.0 3L3
HOH
 6.757
5.288
 N
N
 OAE
O
GLN D:143 D:143 89.0 0.494 H -56.7 -45.4 89.0 0.494 0.0 3L3
HOH
 6.858
3.098
 N
CG
 OAE
O
4rac 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 67.0 0.372 H -58.7 -44.4 67.0 0.372 0.0 3L4
HOH
 6.897
5.106
 N
N
 OAE
O
GLN B:143 B:143 82.0 0.456 H -69.1 -44.6 82.0 0.456 0.0 3L4
HOH
 6.858
2.920
 N
O
 OAE
O
GLN C:143 C:143 82.0 0.456 H -71.5 -40.6 82.0 0.456 0.0 3L4
HOH
 6.566
5.115
 N
N
 OAC
O
GLN D:143 D:143 87.0 0.483 H -57.5 -39.9 87.0 0.483 0.0 3L4
HOH
 7.407
9.763
 N
CG
 OAF
O
4rad 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 138.0 0.767 H -61.1 -46.0 138.0 0.767 0.0 3L5
MG
HOH
 6.039
7.472
4.456
 H
H
H
 OAG
MG
O
GLN B:143 B:143 58.0 0.322 H -69.1 -43.3 58.0 0.322 0.0 3L5
MG
HOH
 5.971
7.250
3.310
 H
H
HE22
 OAG
MG
O
GLN C:143 C:143 89.0 0.494 H -66.4 -41.8 89.0 0.494 0.0 3L5
HOH
 6.022
2.361
 H
OE1
 OAG
O
GLN D:143 D:143 87.0 0.483 H -65.0 -36.0 87.0 0.483 0.0 3L5
HOH
 6.326
4.321
 H
H
 OAH
O
GLN E:143 E:143 73.0 0.406 H -66.2 -36.1 NA NA NA
GLN F:143 F:143 96.0 0.533 H -63.4 -42.0 NA NA NA
GLN G:143 G:143 80.0 0.444 H -68.7 -46.6 NA NA NA
GLN H:143 H:143 97.0 0.539 H -62.6 -42.5 NA NA NA
4ran 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 85.0 0.472 H -57.8 -46.8 85.0 0.472 0.0 3L6
HOH
 6.902
5.258
 N
N
 OAF
O
GLN B:143 B:143 87.0 0.483 H -62.7 -45.6 87.0 0.483 0.0 3L6
HOH
 6.977
8.124
 N
N
 OAD
O
GLN C:143 C:143 77.0 0.428 H -60.6 -38.7 77.0 0.428 0.0 3L6
HOH
 6.528
6.804
 N
O
 OAD
O
GLN D:143 D:143 100.0 0.556 H -59.8 -51.0 100.0 0.556 0.0 3L6
 6.889
 N
 OAD
4rao 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 88.0 0.489 H -59.1 -38.6 88.0 0.489 0.0 3L7
HOH
 6.700
2.426
 N
O
 OAG
O
GLN B:143 B:143 113.0 0.628 H -56.4 -40.4 113.0 0.628 0.0 3L7
HOH
 6.816
5.167
 N
N
 OAG
O
GLN C:143 C:143 98.0 0.544 H -49.9 -48.9 98.0 0.544 0.0 3L7
HOH
 6.829
2.359
 N
O
 OAG
O
GLN D:143 D:143 91.0 0.506 H -60.3 -37.7 91.0 0.506 0.0 3L7
HOH
 6.884
2.574
 N
O
 OAF
O
4raq 1 P00492 100.0 3e-161 X-RAY
 2015-01-07 GLN A:143 A:143 83.0 0.461 H -67.1 -27.9 83.0 0.461 0.0 3L8
HOH
 6.854
7.591
 N
CG
 OAD
O
GLN B:143 B:143 79.0 0.439 H -64.3 -43.3 79.0 0.439 0.0 3L8
HOH
 6.773
2.511
 N
O
 OAD
O
GLN C:143 C:143 98.0 0.544 H -50.9 -45.4 98.0 0.544 0.0 3L8
MG
HOH
 7.071
9.586
2.854
 N
N
NE2
 OAD
MG
O
GLN D:143 D:143 95.0 0.528 H -56.9 -46.2 95.0 0.528 0.0 3L8
HOH
 7.084
5.018
 N
N
 OAE
O
4ijq 1 P00492 100.0 4e-161 X-RAY
 2013-03-27 GLN A:149 A:143 89.0 0.494 H -58.9 -42.2 89.0 0.494 0.0 SV2
HOH
 6.876
2.784
 N
OE1
 OAH
O
GLN B:149 B:143 86.0 0.478 H -56.6 -47.6 86.0 0.478 0.0 SV2
HOH
 6.685
2.700
 N
O
 OAH
O
GLN C:149 C:143 90.0 0.5 H -56.4 -36.6 90.0 0.5 0.0 SV2
HOH
 6.778
2.782
 N
O
 OAH
O
GLN D:149 D:143 79.0 0.439 H -53.4 -46.5 79.0 0.439 0.0 SV2
HOH
 6.809
2.600
 N
OE1
 OAD
O
4kn6 1 P00492 100.0 1e-160 X-RAY
 2013-08-14 GLN A:142 A:143 94.0 0.522 H -55.2 -47.5 94.0 0.522 0.0 1RP
HOH
 6.143
7.170
 H
H
 OAG
O
6bnj 1 P00492 99.08 6e-160 X-RAY
 2017-12-06 GLN A:144 A:143 81.0 0.45 H -62.5 -39.3 81.0 0.45 0.0 WPG
HOH
 6.529
2.675
 N
NE2
 OAI
O
GLN B:144 B:143 89.0 0.494 H -56.7 -42.1 89.0 0.494 0.0 WPG
HOH
 6.646
2.594
 N
NE2
 OAI
O
GLN C:144 C:143 71.0 0.394 H -56.9 -41.8 71.0 0.394 0.0 WPG
HOH
 6.760
3.565
 N
O
 OAI
O
GLN D:144 D:143 82.0 0.456 H -64.1 -42.0 82.0 0.456 0.0 WPG
HOH
 6.711
2.355
 N
O
 OAE
O
5hia 1 P00492 99.08 8e-160 X-RAY
 2017-01-18 GLN A:150 A:143 93.0 0.517 H -62.4 -37.1 93.0 0.517 0.0 YPG
HOH
 6.663
5.047
 N
N
 OAI
O
GLN B:150 B:143 91.0 0.506 H -59.3 -38.9 91.0 0.506 0.0 YPG
HOH
 6.748
2.675
 N
NE2
 OAI
O
GLN C:150 C:143 79.0 0.439 H -57.9 -44.5 79.0 0.439 0.0 YPG
HOH
 6.685
4.015
 N
O
 OAI
O
GLN D:150 D:143 89.0 0.494 H -56.7 -42.9 89.0 0.494 0.0 YPG
HOH
 6.702
2.853
 N
O
 OAI
O
5brn 1 P00492 98.62 3e-159 X-RAY
 2015-10-14 GLN A:144 A:143 91.0 0.506 H -68.4 -27.3 91.0 0.506 0.0 4X2
HOH
 7.247
5.262
 N
N
 O01
O
GLN B:144 B:143 54.0 NA H -61.8 -45.0 54.0 NA NA 4X2
HOH
 6.918
6.437
 N
N
 O04
O
GLN C:144 C:143 89.0 0.494 H -59.5 -40.9 89.0 0.494 0.0 4X2
HOH
 7.214
5.109
 N
N
 O04
O
GLN D:144 D:143 80.0 0.444 H -61.9 -47.0 80.0 0.444 0.0 4X2
HOH
 6.896
5.073
 N
N
 O04
O
5bsk 1 P00492 98.62 3e-159 X-RAY
 2015-09-23 GLN A:144 A:143 108.0 0.6 H -69.3 -40.9 108.0 0.6 0.0 4X7
HOH
 6.911
6.805
 N
N
 OAC
O
GLN B:144 B:143 84.0 0.467 H -59.9 -41.2 84.0 0.467 0.0 4X7
HOH
 6.940
5.084
 N
N
 OAC
O
GLN C:144 C:143 94.0 0.522 H -59.9 -34.9 94.0 0.522 0.0 4X7
HOH
 7.210
7.040
 N
O
 OAF
O
GLN D:144 D:143 89.0 0.494 H -60.4 -43.2 89.0 0.494 0.0 4X7
HOH
 7.553
5.425
 N
N
 OAC
O
5w8v 1 P00492 100.0 7e-159 X-RAY
 2017-08-30 GLN A:141 A:143 87.0 0.483 H -57.0 -40.7 87.0 0.483 0.0 9YP
HOH
 7.006
2.791
 N
OE1
 OAH
O
GLN B:141 B:143 84.0 0.467 H -59.5 -42.5 84.0 0.467 0.0 9YP
HOH
 6.842
2.620
 N
OE1
 OAG
O
GLN C:141 C:143 86.0 0.478 H -56.9 -42.2 86.0 0.478 0.0 9YP
HOH
 6.804
2.282
 N
OE1
 OAG
O
GLN D:141 D:143 77.0 0.428 H -56.4 -47.2 77.0 0.428 0.0 9YP
HOH
 6.769
2.505
 N
OE1
 OAH
O
1d6n 1 P00492 99.07 6e-157 X-RAY
 1999-12-30 GLN A:140 A:143 106.0 0.589 H -50.0 -65.4 106.0 0.589 0.0 PRP
HOH
 6.252
3.210
 N
NE2
 O3P
O
GLN B:140 B:143 65.0 0.361 H -44.9 -53.1 65.0 0.361 0.0 MG
PRP
HOH
 9.465
5.494
3.830
 N
N
NE2
 MG
O2P
O
2vfa 1 P20035,P00492 80.48 3e-122 X-RAY
 2008-06-17 GLN A:152 A:152 84.0 0.467 H -59.8 -33.3 84.0 0.467 0.0 SO4
HOH
 6.530
6.581
 N
NE2
 O3
O
GLN B:152 B:152 96.0 0.533 H -61.9 -43.3 96.0 0.533 0.0 SO4
HOH
 5.320
5.791
 N
NE2
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00492-f1 1 P00492 100.0 2e-162 GLN A:144 A:144 93.0 0.517 H -60.1 -44.5